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Volumn 38, Issue 1-2, 2000, Pages 175-181

BCR-ABL directed immunotherapy: A virtual reality?

Author keywords

BCR ABL; HLA; Junctional region peptides; T cells

Indexed keywords

HLA ANTIGEN; HYBRID PROTEIN; ONCOPROTEIN;

EID: 0034052906     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428190009060331     Document Type: Article
Times cited : (7)

References (56)
  • 4
    • 0342275939 scopus 로고    scopus 로고
    • manuscript in preparation
    • Kessler J.H. et al manuscript in preparation.
    • Kessler, J.H.1
  • 7
    • 0032005138 scopus 로고    scopus 로고
    • Dendritic cells stimulate the expansion of bcr-abl specific CD8+ T cells with cytotoxic activity against leukemia cells from patients with chronic myeloid leukemia
    • Nieda M., Nicol A., KikuchiA., Kashiwase K., Taylor K., Suzuki K., Tadokoro K. and Juji T. (1998) Dendritic cells stimulate the expansion of bcr-abl specific CD8+ T cells with cytotoxic activity against leukemia cells from patients with chronic myeloid leukemia. BLOOD, 91, 977-983.
    • (1998) BLOOD , vol.91 , pp. 977-983
    • Nieda, M.1    Nicol, A.2    Kashiwase, K.3    Taylor, K.4    Suzuki, K.5    Tadokoro, K.6    Juji, T.7
  • 8
    • 0030871348 scopus 로고    scopus 로고
    • Peptides derived from the whole sequence of BCR-ABL bind to several class I molecules allowing specific induction of human cytotoxic T lymphocytes
    • Buzyn A., Ostankovitch M., Zerbib A., Kemula M., Connan F., Varet B., Guillet J-G and Choppin J. (1997) Peptides derived from the whole sequence of BCR-ABL bind to several class I molecules allowing specific induction of human cytotoxic T lymphocytes. European Journal of Immunology, 27, 2066-2072.
    • (1997) European Journal of Immunology , vol.27 , pp. 2066-2072
    • Buzyn, A.1    Ostankovitch, M.2    Zerbib, A.3    Kemula, M.4    Connan, F.5    Varet, B.6    Guillet, J.-G.7    Choppin, J.8
  • 9
    • 0030946078 scopus 로고    scopus 로고
    • HLA-DR1-restricted bcr-abl (b3a2)-specific CD4+ T lymphocytes respond to dendritic cells pulsed with b3a2 peptide and antigen-presenting cells exposed to b3a2 containing cell lysates
    • Mannering S.I., McKenzie J.L., Fearnley D.B. and Hart D.N.J. (1997) HLA-DR1-restricted bcr-abl (b3a2)-specific CD4+ T lymphocytes respond to dendritic cells pulsed with b3a2 peptide and antigen-presenting cells exposed to b3a2 containing cell lysates. BLOOD, 90, 290-297.
    • (1997) BLOOD , vol.90 , pp. 290-297
    • Mannering, S.I.1    McKenzie, J.L.2    Fearnley, D.B.3    Hart, D.N.J.4
  • 10
    • 0343145502 scopus 로고    scopus 로고
    • unpublished observation
    • 10) Ten Bosch G.J.A. et al unpublished observation.
    • , vol.10
    • Ten Bosch, G.J.A.1
  • 11
    • 0029815159 scopus 로고    scopus 로고
    • BCR/ABL leukemia oncogene fusion peptides selectively bind to certain HLA-DR alleles and can be recognized by T cells found at low frequency in the repertoire of normal donors
    • Pawelec G., Max H., Halder Th., Bruserud Ø, Merl A., Da Silva P., and Kalbacher H. (1996) BCR/ABL leukemia oncogene fusion peptides selectively bind to certain HLA-DR alleles and can be recognized by T cells found at low frequency in the repertoire of normal donors. BLOOD, 88, 2118-212.
    • (1996) BLOOD , vol.88 , pp. 2118-2212
    • Pawelec, G.1    Max, H.2    Halder, T.3    Bruserud, Ø.4    Merl, A.5    Da Silva, P.6    Kalbacher, H.7
  • 12
    • 0029967001 scopus 로고    scopus 로고
    • Recognition of BCR-ABL positive leukemic blasts by human CD4+ T cells elicited by primary in vitro immunisation with a BCR-ABL breakpoint peptide
    • Ten Bosch G.J.A., Joosten A.M., Kessler J.H., Melief C.J.M. and Leeksma O.C. (1996) Recognition of BCR-ABL positive leukemic blasts by human CD4+ T cells elicited by primary in vitro immunisation with a BCR-ABL breakpoint peptide. BLOOD, 88, 3522-3527.
    • (1996) BLOOD , vol.88 , pp. 3522-3527
    • Ten Bosch, G.J.A.1    Joosten, A.M.2    Kessler, J.H.3    Melief, C.J.M.4    Leeksma, O.C.5
  • 13
    • 0032213388 scopus 로고    scopus 로고
    • CD4+ Cytotoxic T-cell clones specific for bcr-abl b3a2 fusion peptide augment colony formation by chronic myelogenous leukemia cells in a b3a2-specific and HLA-DR-restricted manner
    • Yasukawa M., Ohminami H., Kaneko S., Yakushijin Y., Nishimura Y., Inokuchi K., Miyakuni T., Nakao S., Kishi K., Kubonishi I., Dan K. and Fujita S. (1998) CD4+ Cytotoxic T-cell clones specific for bcr-abl b3a2 fusion peptide augment colony formation by chronic myelogenous leukemia cells in a b3a2-specific and HLA-DR-restricted manner. BLOOD, 92, 3355-3361.
    • (1998) BLOOD , vol.92 , pp. 3355-3361
    • Yasukawa, M.1    Ohminami, H.2    Kaneko, S.3    Yakushijin, Y.4    Nishimura, Y.5    Inokuchi, K.6    Miyakuni, T.7    Nakao, S.8    Kishi, K.9    Kubonishi, I.10    Dan, K.11    Fujita, S.12
  • 16
    • 0031442008 scopus 로고    scopus 로고
    • Naturally processed tissue-and differentiation stage-specific autologous peptides bound by HLA class I and II molecules of chronic myeloid leukemia blasts
    • Papadopoulos K.P., Suciu-Foca N., Hesdorffer C.S., Tugulea S., Maffei A. and Harris P.E. (1997) Naturally processed tissue-and differentiation stage-specific autologous peptides bound by HLA class I and II molecules of chronic myeloid leukemia blasts. BLOOD, 90, 4938-4946.
    • (1997) BLOOD , vol.90 , pp. 4938-4946
    • Papadopoulos, K.P.1    Suciu-Foca, N.2    Hesdorffer, C.S.3    Tugulea, S.4    Maffei, A.5    Harris, P.E.6
  • 17
    • 0032531925 scopus 로고    scopus 로고
    • A novel site for ubiquitination: The N-terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein
    • Breitschopf K., Bengal E., Ziv T., Admon A. and Ciechanover A. (1998) A novel site for ubiquitination: the N-terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein. The Embo Journal, 17, 5964-5973.
    • (1998) The Embo Journal , vol.17 , pp. 5964-5973
    • Breitschopf, K.1    Bengal, E.2    Ziv, T.3    Admon, A.4    Ciechanover, A.5
  • 18
    • 0032488846 scopus 로고    scopus 로고
    • The proteasome: Paradigm of a self-compartmentalizing protease
    • Baumeister W., Walz J., Zühl F. and Seemüller E. (1998) The proteasome: paradigm of a self-compartmentalizing protease Cell, 92, 367-380.
    • (1998) Cell , vol.92 , pp. 367-380
    • Baumeister, W.1    Walz, J.2    Zühl, F.3    Seemüller, E.4
  • 19
    • 0027980319 scopus 로고
    • Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
    • Rock K.L., Gramm C., Rothstein L., Clark K., Stein R., Dick L., Hwang D. and Goldberg A. (1994) Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell, 78, 761-771.
    • (1994) Cell , vol.78 , pp. 761-771
    • Rock, K.L.1    Gramm, C.2    Rothstein, L.3    Clark, K.4    Stein, R.5    Dick, L.6    Hwang, D.7    Goldberg, A.8
  • 20
    • 0030926777 scopus 로고    scopus 로고
    • Lactacystin and clasto-lactacystin β-lactone modify multiple proteasome β-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation
    • Craiu A., Gaczynska M., Akopian T., Gramm C.F., Fenteany G., Goldberg A.L. and Rock K.L. (1997) Lactacystin and clasto-lactacystin β-lactone modify multiple proteasome β-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation. The Journal of Biological Chemistry, 272, 13437-13445.
    • (1997) The Journal of Biological Chemistry , vol.272 , pp. 13437-13445
    • Craiu, A.1    Gaczynska, M.2    Akopian, T.3    Gramm, C.F.4    Fenteany, G.5    Goldberg, A.L.6    Rock, K.L.7
  • 24
    • 0021802841 scopus 로고
    • Fused transcript of abl and ber genes in chronic myelogenous leukemia
    • Shtivelman E., Lifshitz B., Gale R.P. and Canaani E. (1985) Fused transcript of abl and ber genes in chronic myelogenous leukemia. Nature, 315, 550-554.
    • (1985) Nature , vol.315 , pp. 550-554
    • Shtivelman, E.1    Lifshitz, B.2    Gale, R.P.3    Canaani, E.4
  • 26
    • 0022997481 scopus 로고
    • Alternative splicing of RNAs transcribed from the human abl gene and from the BCR-ABL fused gene
    • Shtivelman E., Lifshitz B., Gale R.P., Roe B.A. and Canaani E. (1986) Alternative splicing of RNAs transcribed from the human abl gene and from the BCR-ABL fused gene. Cell, 47, 277-284.
    • (1986) Cell , vol.47 , pp. 277-284
    • Shtivelman, E.1    Lifshitz, B.2    Gale, R.P.3    Roe, B.A.4    Canaani, E.5
  • 27
    • 0032899180 scopus 로고    scopus 로고
    • Two patients with novel BCR/ABL fusion transcripts (e8a2 and e13a2) resulting from translocation breakpoints within BCR exons
    • How G.F., Lim L.C., Kulkarni S., Tan L.T., Tan P. and Cross N.C.P. (1999) Two patients with novel BCR/ABL fusion transcripts (e8a2 and e13a2) resulting from translocation breakpoints within BCR exons British Journal of Haematology, 105, 434-436.
    • (1999) British Journal of Haematology , vol.105 , pp. 434-436
    • How, G.F.1    Lim, L.C.2    Kulkarni, S.3    Tan, L.T.4    Tan, P.5    Cross, N.C.P.6
  • 29
    • 0028090030 scopus 로고
    • Heterogeneity of the breakpoint in the ABL gene in cases with BCR/ABL transcript lacking ABL exon a2
    • Iwata S., Mizutani S., Nakazawa S. and Yata J-i. (1994) Heterogeneity of the breakpoint in the ABL gene in cases with BCR/ABL transcript lacking ABL exon a2. Leukemia, 8, 1696-1702.
    • (1994) Leukemia , vol.8 , pp. 1696-1702
    • Iwata, S.1    Mizutani, S.2    Nakazawa, S.3    Yata, J.-I.4
  • 30
    • 0025763664 scopus 로고
    • bcr-abl mRNA lacking abl exon A2 detected by polymerase chain reaction in a chronic myelogenous leukemia
    • Van der Plas D.C., Soekarman D., van Gent A.M., Grosveld G. and Hagemeijer A. (1991) bcr-abl mRNA lacking abl exon A2 detected by polymerase chain reaction in a chronic myelogenous leukemia. Leukemia, 5, 457-461.
    • (1991) Leukemia , vol.5 , pp. 457-461
    • Van Der Plas, D.C.1    Soekarman, D.2    Van Gent, A.M.3    Grosveld, G.4    Hagemeijer, A.5
  • 33
    • 4243970980 scopus 로고    scopus 로고
    • Translin recognition site sequences flank translocation breakpoints in a Philadelphia chromosome positive chronic myeloid leukemia patient expressing a novel type of chimaeric BCR-ABL transcript (e8-1NT-a2)
    • Martinelli G., Terragna C., Amabile M., Montefusco V., Testoni N., Ottaviani E., de Vivo A., Mianulli A., Saglio G.and Tura S. (1998) Translin recognition site sequences flank translocation breakpoints in a Philadelphia chromosome positive chronic myeloid leukemia patient expressing a novel type of chimaeric BCR-ABL transcript (e8-1NT-a2). BLOOD, 92, 93a.
    • (1998) BLOOD , vol.92
    • Martinelli, G.1    Terragna, C.2    Amabile, M.3    Montefusco, V.4    Testoni, N.5    Ottaviani, E.6    De Vivo, A.7    Mianulli, A.8    Saglio, G.9    Tura, S.10
  • 35
    • 0031729417 scopus 로고    scopus 로고
    • A novel BCR-ABL fusion gene (e2-la) in a patient with Philadelphia-positive chronic myelogenous leukemia and an aggressive clinical course
    • Byrne J.L., Carter G.I., Davies J.M., Haynes A.P., Russell N.H. and Cross N.C.P. (1998) A novel BCR-ABL fusion gene (e2-la) in a patient with Philadelphia-positive chronic myelogenous leukemia and an aggressive clinical course. British Journal of Haematology, 103, 791-794.
    • (1998) British Journal of Haematology , vol.103 , pp. 791-794
    • Byrne, J.L.1    Carter, G.I.2    Davies, J.M.3    Haynes, A.P.4    Russell, N.H.5    Cross, N.C.P.6
  • 37
    • 0028181636 scopus 로고
    • P190BCR-ABL chronic mycloid leukaemia: The missing link with chronic myelomonocytic leukaemia?
    • Melo J.V., Myint H., Galton D.A. and Goldman J.M. (1994) P190BCR-ABL chronic mycloid leukaemia: the missing link with chronic myelomonocytic leukaemia?. Leukemia, 8, 208-211.
    • (1994) Leukemia , vol.8 , pp. 208-211
    • Melo, J.V.1    Myint, H.2    Galton, D.A.3    Goldman, J.M.4
  • 39
    • 0029895899 scopus 로고    scopus 로고
    • P190BCR-ABL mRNA is expressed at low levels in p210-positive chronic myeloid and acute lymphoblastic leukemia
    • Rhee F. van. Hochhaus A., Lin F., Melo J.V., Goldman J.M. and Cross N.C.P. (1996) P190BCR-ABL mRNA is expressed at low levels in p210-positive chronic myeloid and acute lymphoblastic leukemia. BLOOD, 87, 5213-5221.
    • (1996) BLOOD , vol.87 , pp. 5213-5221
    • Rhee, F.1    Van Hochhaus, A.2    Lin, F.3    Melo, J.V.4    Goldman, J.M.5    Cross, N.C.P.6
  • 41
    • 0031954858 scopus 로고    scopus 로고
    • Regulation of KIR expression in human T lymphocytes. A safety mechanism which may impair protective T cell responses
    • Mingari M.C., Moretta A. and Moretta L. (1998) Regulation of KIR expression in human T lymphocytes. A safety mechanism which may impair protective T cell responses. Immunology Today, 19, 153-157.
    • (1998) Immunology Today , vol.19 , pp. 153-157
    • Mingari, M.C.1    Moretta, A.2    Moretta, L.3
  • 44
    • 0032521903 scopus 로고    scopus 로고
    • Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology
    • Hemmer B., Vergeli M., Gran B., Ling N., Conlon P., Pinilla C., Houghten R., McFarland H.F. and Martin R. (1998) Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology. Journal nf Immunology, 160, 3631-363.
    • (1998) Journal Nf Immunology , vol.160 , pp. 3631-4363
    • Hemmer, B.1    Vergeli, M.2    Gran, B.3    Ling, N.4    Conlon, P.5    Pinilla, C.6    Houghten, R.7    McFarland, H.F.8    Martin, R.9
  • 46
    • 25544441223 scopus 로고
    • Cross reactivity of BCR-ABL peptide specific T cells with EBV transformed B cells
    • Ten Bosch G.J.A., Joosten A.M., Melief C.J.M. and Leeksma O.C. (1994) Cross reactivity of BCR-ABL peptide specific T cells with EBV transformed B cells. BLOOD, 84, 432a.
    • (1994) BLOOD , vol.84
    • Ten Bosch, G.J.A.1    Joosten, A.M.2    Melief, C.J.M.3    Leeksma, O.C.4
  • 47
    • 0028786297 scopus 로고
    • Detection of major bcr-abl gene expression at a very low level in blood cells of some healthy individuals
    • Biernaux C., Loos. M., Sels. A., Huez G. and Stryckmans (1995) Detection of major bcr-abl gene expression at a very low level in blood cells of some healthy individuals. BLOOD, 86, 3118-3122.
    • (1995) BLOOD , vol.86 , pp. 3118-3122
    • Biernaux, C.1    Loos, M.2    Sels, A.3    Huez, G.4    Stryckmans5
  • 48
    • 0032211172 scopus 로고    scopus 로고
    • The presence of typical and atypical BCR-ABL fusion genes in leukocytes of normal individuals: Biologic significance and implications for the assessment of minimal residual disease
    • Bose S., Deininger M., Gora-Tybor M., Goldman J. and Melo J.V. (1998) The presence of typical and atypical BCR-ABL fusion genes in leukocytes of normal individuals: biologic significance and implications for the assessment of minimal residual disease. BLOOD, 92, 3362-3367.
    • (1998) BLOOD , vol.92 , pp. 3362-3367
    • Bose, S.1    Deininger, M.2    Gora-Tybor, M.3    Goldman, J.4    Melo, J.V.5
  • 52
    • 0032485487 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class-I-restricted CTLs
    • Albert M.L., Sauter B. and Bardwaj N. (1998) Dendritic cells acquire antigen from apoptotic cells and induce class-I-restricted CTLs. Nature, 392, 86-89.
    • (1998) Nature , vol.392 , pp. 86-89
    • Albert, M.L.1    Sauter, B.2    Bardwaj, N.3
  • 53
    • 0030812812 scopus 로고    scopus 로고
    • Maintenance of human T cell anergy: Blocking of 1L-2 gene transcription by activated Rap1
    • Boussiotis V.K., Freeman G.J., Berezovskaya A., Barber D.L. and Nadler L.M. (1997) Maintenance of human T cell anergy: blocking of 1L-2 gene transcription by activated Rap1. SCIENCE, 278, 124-127.
    • (1997) SCIENCE , vol.278 , pp. 124-127
    • Boussiotis, V.K.1    Freeman, G.J.2    Berezovskaya, A.3    Barber, D.L.4    Nadler, L.M.5
  • 55
    • 0037967119 scopus 로고    scopus 로고
    • A new melanoma antigen. PRAME, is identified as a BCR-ABL-inducible gene in TF-1 cells
    • Watai K., Tojo T., Nagamura -Inoue T., Tsujimura H., Nagamura F., Tani K. and Asano S. (1997) A new melanoma antigen. PRAME, is identified as a BCR-ABL-inducible gene in TF-1 cells. BLOOD, 90, 197a.
    • (1997) BLOOD , vol.90
    • Watai, K.1    Tojo, T.2    Nagamura, T.3    Tsujimura, H.4    Nagamura, F.5    Tani, K.6    Asano, S.7
  • 56
    • 0032109778 scopus 로고    scopus 로고
    • Chromosomal rearrangements occur in s. Cerevisiae rfal mutator mutants due to mutagenic lesions processed by double-strand-break repair
    • Chen C., Umezu K. and Kolodner R. (1998) Chromosomal rearrangements occur in s. cerevisiae rfal mutator mutants due to mutagenic lesions processed by double-strand-break repair. Molecular Cell, 2, 9-22.
    • (1998) Molecular Cell , vol.2 , pp. 9-22
    • Chen, C.1    Umezu, K.2    Kolodner, R.3


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