Absence of telomerase activity and telomerase catalytic subunit mRNA in melanocyte cultures

British Journal of Cancer

Volumn 82, Issue 5, 2000, Pages 1051-1057

  Dhaene, K ^a   Vancoillie, G ^b   Lambert, J ^b   Naeyaert, J M ^b   Van Marck, E ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

hTERT; Ki S2; Ki S5; Melanoma; Proliferation; Telomerase

Indexed keywords

MESSENGER RNA; TELOMERASE;

ARTICLE; CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBUNIT; EPIDERMIS CELL; HUMAN; HUMAN CELL; MELANOCYTE; MELANOMA; NEWBORN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; STEM CELL;

EID: 0034052278     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.1999.1041     Document Type: Article

References (59)

1. Ackerman AB (1988) What naevus is dysplastic, a syndrome and the commonest precursor of malignant melanoma? A riddle and an answer. Histopathology 13: 241-256
2. Albino AP (1995) Genes involved in melanoma susceptibility and progression. Curr Opin Oncol 7: 162-169
3. Allsopp RC, Chang E, Kashefi AM, Rogaev EI, Piatyszek MA, Shay JW and Harley CB (1995) Telomere shortening is associated with cell division in vitro and in vivo. Exp Cell Res 220: 194-200
4. Balasubramanian S, Kim KH, Ahmad N and Mukhtar H (1999) Activation of telomerase and its association with G1-phase of the cell cycle during UVB-induced skin tumorigenesis in SKH-1 hairless mouse. Oncogene 18: 1297-1302
5. Belair CD, Yeager TR, Lopez PM and Reznikoff CA (1997) Telomerase activity: a biomarker of cell proliferation, not malignant transformation. Proc Natl Acad Sci USA 94: 13677-13682
6. Bosserhoff AK, Glaessl A, Stolz W and Buettner R (1997) Detection of telomerase activity in skin, melanocytic naevi, and melanoma by telomerase PCR ELISA. Biochemica 3: 16-18
7. Boyle P, Maisonneuve P and Doré J (1995) Epidemiology of malignant melanoma. Br Med Bull 51: 523-547
8. Briggs JC (1985) Melanoma precursor lesions and borderline melanomas. Histopathology 9: 1251-1262
9. Cong YS, Wen JP and Bacchetti S (1999) The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter. Hum Mol Genet 8: 137-142
10. Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW, Harley CB and Bacchetti S (1992) Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 11: 1921-1929
11. Counter CM, Gupta J, Harley CB, Leber B and Bacchetti S (1995) Telomerase activity in normal leucocytes and in hematologic malignancies. Blood 85: 2315-2320
12. Cramer SF (1991) The origin of epidermal melanocytes. Arch Pathol Lab Med 115: 115-119
13. Cuthbert AP, Bond J, Trott DA, Gill S, Broni J, Marriott A, Khoudoli G, Parkinson EK, Cooper CS and Newbold RF (1999) Telomerase repressor sequences on chromosome 3 and induction of permanent growth arrest in human breast cancer cells. J Natl Cancer Inst 91: 37-45
14. deLange T (1998) Telomeres and senescence: ending the debate. Science 279: 334-335
15. Dhaene K, Hübner R, Kumar-Singh S, Weyn B and Van Marck E (1998) Telomerase activity in human pleural mesothelioma. Thorax 53: 915-918
16. Dhaene K, Wauters J, Weyn B, Timmermans J-P and Van Marck E (1999) Expression profile of telomerase subunits in human pleural mesothelioma. J Pathol (in press)
17. Elwood JM and Jopson J (1997) Melanoma and sun exposure: an overview of published studies. Int J Cancer 73: 198-203
18. Feng J, Funk WD, Wang SS, Weinrich SL, Avilion AA, Chiu CP, Adams RR, Chang E, Allsopp RC, Yu J, Le S, West MD, Harley CB, Andrews WH, Greider CW and Villeponteau B (1995) The RNA component of human telomerase. Science 269: 1236-1241
19. Gilchrest BA, Park H-Y, Eller M and Yaar M (1998) The photobiology of the tanning response. In: The Pigmentary System: Physiology and Pathophysiology, Nordlund JJ, Boissy RE, Hearing VJ, King RA and Ortonne J-P (eds), pp. 359-372. Oxford University Press: New York
20. Glaessl A, Bosserhoff AK, Buettner R, Hohenleutner U, Landthaler M and Stolz W (1999) Increase in telomerase activity during progression of melanocytic cells from melanocytic naevi to malignant melanomas. Arch Dermatol Res 291: 81-87
21. Greaves M (1996) Is telomerase activity in cancer due to selection of stem cells and differentiation arrest. Trends Genet 12: 127-128
22. Greider CW (1998) Telomerase activity, cell proliferation, and cancer. Proc Natl Acad Sci USA 95: 90-92
23. Harle-Bachor C and Boukamp P (1996) Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes. Proc Natl Acad Sci USA 93: 6476-6481
24. Harley CB (1991) Telomere loss: mitotic clock or genetic time bomb. Mutat Res 256: 271-282
25. Harrington L, McPhail T, Mar V, Zhou W, Oulton R, Bass MB, Arruda I and Robinson MO (1997) A mammalian telomerase-associated protein. Science 275: 973-977
26. Hastrup N, Osterlind A, Drzewiecki KT and Hou-Jensen K (1991) The presence of dysplastic nevus remnants in malignant melanomas. A population-based study of 551 malignant melanomas. Am J Dermatopathol 13: 378-385
27. Holt SE, Wright WE and Shay JW (1996) Regulation of telomerase activity in immortal cell lines. Mol Cell Biol 16: 2932-2939
28. Holt SE, Aisner DL, Shay JW and Wright WE (1997) Lack of cell cycle regulation of telomerase activity in human cells. Proc Natl Acad Sci USA 94: 10687-10692
29. International Agency for Research on Cancer (1992) IARC monographs on the Evaluation of Carcinogenic Risks to Humans: Ultraviolet Radiation, Vol. 55 IARC: Lyon
30. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL and Shay JW (1994) Specific association of human telomerase activity with immortal cells and cancer. Science 266: 2011-2015
31. Kipling D (1995) The Telomere. Oxford University Press: Oxford
32. Kipling D (1997) Telomere structure and telomerase expression during mouse development and tumorigenesis. Eur J Cancer 33: 792-800
33. Klingel R, Mincheva A, Kahn T, Gissmann L, Dippold W, Meyer zum Buschenfelde KH and zur Hausen H (1987) An amplification unit in human melanoma cells showing partial homology with sequences of human papillomavirus type 9 and with nuclear antigen 1 of the Epstein-Barr virus. Cancer Res 47: 4485-4492
34. Kolquist KA, Ellisen LW, Counter CM, Meyerson M, Tan LK, Weinberg RA, Haber DA and Gerald WL (1998) Expression of TERT in early premalignant lesions and a subset of cells in normal tissues. Nat Genet 19: 182-186
35. Kreipe H, Wacker HH, Heidebrecht H-J, Haas K, Hauberg M, Tiemann M and Parwaresch R (1993) Determination of the growth fraction in non-Hodgkin's lymphomas by monoclonal antibody Ki-S5 directed against a formalin-resistant epitope of the Ki-67 antigen. Am J Pathol 142: 1689-1694
36. Lambert J, Onderwater J, Vander Haeghen Y, Vancoillie G, Koerten HK, Mommaas AM and Naeyaert JM (1998) Myosin V colocalises with melanosomes and subcortical actin bundles not associated with stress fibers in human epidermal melanocytes. J Invest Dermatol 111: 835-840
37. Libow LF, Scheide S and DeLeo VA (1988) Ultraviolet radiation acts as an independent mitogen for normal human melanocytes in culture. Pigment Cell Res 1: 397-401
38. Mantell LL and Greider CW (1994) Telomerase activity in germline and embryonic cells of Xenopus.EMBO J 13: 3211-3217
39. Naeyaert JM, Eller M, Gordon PR, Park H-Y and Gilchrest BA (1991) Pigment content of cultured human melanocytes does not correlate with tyrosinase message level. Br J Dermatol 125: 297-303
40. Nakamura TM, Morin GB, Chapman KB, Weinrich SL, Andrews WH, Lingner J, Harley CB and Cech TR (1997) Telomerase catalytic subunit homologs from fission yeast and human. Science 277: 955-959
41. Nakayama J, Tahara H, Tahara E, Saito M, Ito K, Nakamura H, Nakanishi T, Ide T and Ishikawa F (1998) Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas. Nat Genet 18: 65-68
42. Newbold RF, Overell RW and Connell JR (1982) Induction of immortality is an early event in malignant transformation of mammalian cells by carcinogens. Nature 299: 633-635
43. Pandita TK, Hall EJ, Hei TK, Piatyszek MA, Wright WE, Piao CQ, Pandita RK, Willey JC, Geard CR, Kastan MB and Shay JW (1996) Chromosome end-to-end associations and telomerase activity during cancer progression in human cells after treatment with alpha-particles simulating radon progeny. Oncogene 13: 1423-1430
44. Parris CN, Jezzard S, Silver A, MacKie R, McGregor JM and Newbold RF (1999) Telomerase activity in melanoma and non-melanoma skin cancer. Br J Cancer 79: 47-53
45. Quevedo WC and Fleischmann RD (1980) Developmental biology of mammalian melanocytes. J Invest Dermatol 75: 116-120
46. Ramakrishnan S, Eppenberger U, Mueller H, Shinkai Y and Narayanan R (1998) Expression profile of the putative catalytic subunit of the telomerase gene. Cancer Res 58: 622-625
47. Rhyu MS (1995) Telomeres, telomerase, and immortality. J Natl Cancer Inst 87: 884-894
48. Rudolph P, Knüchel R, Endl E, Heidebrecht H-J, Hofstädter F and Parwaresch R (1998) The immunohistochemical marker Ki-S2: cell cycle kinetics and tissue distribution of a novel proliferation-specific antigen. Mod Pathol 11: 450-456
49. Scheurlen W, Gissmann L, Gross G and zur Hausen H (1986) Molecular cloning of two new HPV types (HPV 37 and HPV 38) from keratoacanthoma and a malignant melanoma. Int J Cancer 37: 505-510
50. Takamiyagi A, Asato T, Nakashima Y and Nonaka S (1998) Association of human papillomavirus type 16 with malignant melanoma. Am J Dermatopathol 20: 69-73
51. Taylor RS, Ramirez RD, Ogoshi M, Chaffins M, Piatyszek MA and Shay JW (1996) Detection of telomerase activity in malignant and nonmalignant skin conditions. J Invest Dermatol 106: 759-765
52. Ueda M, Ouhtit A, Bito T, Nakazawa K, Lübbe J, Ichihashi M, Yamasaki H, and Nakazawa H (1997) Evidence for UV-associated activation of telomerase in human skin. Cancer Res 57: 370-374
53. Ulaner GA, Hu JF, Vu TH, Giudice LC and Hoffman AR (1998) Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts. Cancer Res 58: 4168-4172
54. Weterman MA, Van Muijen GN, Bloemers HP and Ruiter DJ (1994) Molecular markers of melanocytic tumor progression. Lab Invest 70: 593-608
55. Wright WE, Pereira SO and Shay JW (1989) Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts. Mol Cell Biol 9: 3088-3092
56. Wu K, Grandori C, Amacker M, Simon-Vermot N, Polack A, Lingner J and Dallafavera R (1999) Direct activation of TERT transcription by c-Myc. Nat Genet 21: 220-224
57. Wynford-Thomas D (1999) Cellular senescence and cancer. J Pathol 187: 100-111
58. Yamada O, Motoji T and Mizoguchi H (1996) Up-regulation of telomerase activity in human lymphocytes. Biochim Blophys Acta 1314: 260-266
59. Zhu X, Kumar R, Mandal M, Sharma HW, Dhingra U, Sokoloski JA, Hsiao R and Narayanan R (1996) Cell cycle-dependent modulation of telomerase activity in tumor cells. Proc Natl Acad Sci USA 93: 6091-6095