Increase in telomerase activity during progression of melanocytic cells from melanocytic naevi to malignant melanomas

Archives of Dermatological Research

Volumn 291, Issue 2-3, 1999, Pages 81-87

  Glaessl, Alexander ^a   Bosserhoff, Anja Katrin ^a   Buettner, Reinhard ^a   Hohenleutner, Ulrich ^a   Landthaler, Michael ^a   Stolz, Wilhelm ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Malignant melanoma; Melanocytic naevi; Skin; Telomerase activity; Tumor progression

Indexed keywords

TELOMERASE;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; JUVENILE MELANOMA; MAJOR CLINICAL STUDY; MELANOCYTE; MELANOCYTIC NEVUS; MELANOMA; PRIORITY JOURNAL; SKIN; TELOMERE; TUMOR GROWTH;

ADOLESCENT; ADULT; AGED; BIOPSY; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; HUMANS; MELANOMA; MIDDLE AGED; NEOPLASM PROTEINS; NEVUS; POLYMERASE CHAIN REACTION; SKIN; SKIN NEOPLASMS; TELOMERASE; TUMOR CELLS, CULTURED;

EID: 0033049727     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004030050387     Document Type: Article

References (48)

1. Blackburn EH (1991) Structure and function of telomerase. Nature 350:569-573
2. Burger AM, Bibby MC, Double JA (1997) Telomerase activity in normal and malignant mammalian tissues: feasibility of telomerase as a target for cancer chemotherapy. Br J Cancer 75:516-522
3. Chadeneau C, Hay K, Hirte HW, Gallinger S, Bacchetti S (1995) Telomerase activity associated with acquisition of malignancy in human colorectal cancer. Cancer Res 55:2533-2536
4. Clark WH Jr, Elder DE, Guerry D 4th, Epstein MN, Greene MH, Van Horn M (1984) A study of tumor progression: the precursor lesions of superficial spreading and nodular melanoma. Hum Pathol 15:1147-1165
5. Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW, Harley CB, Bacchetti S (1992) Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 11:1921-1929
6. De Wit PE, Van Muijen GN, De Waal RM, Ruiter DJ (1996) Pathology of malignant melanoma, including new markers and techniques in diagnosis and prognosis. Curr Opin Oncol 8:143-151
7. Duggan BD, Wan M, Yu MC, Roman LD, Muderspach LI, Delgadillo E, Li WZ, Martin SE, Dubeau L (1998) Detection of ovarian cancer cells: comparison of a telomerase assay and cytologic examination. J Natl Cancer Inst 90:238-242
8. Elder DE, Clark WH Jr, Elenitsas R, Guerry D 4th, Halpern AC (1993) The early and intermediate precursor lesions of tumor progression in the melanocytic system: common acquired nevi and atypical (dysplastic) nevi. Semin Diagn Pathol 10:18-35
9. Greider CW (1998) Telomerase activity, cell proliferation, and cancer. Proc Natl Acad Sci USA 95:90-92
10. Greider CW, Blackburn EH (1985) Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43:405-413
11. Greider CW, Blackburn EH (1987) The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell 51:887-898
12. Harle-Bachor C, Boukamp P (1996) Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma derived skin keratinocytes. Proc Natl Acad Sci USA 93:6476-6481
13. Harley CB, Kim MW (1996) Important advances in oncology. In: De Vita VT, Hellmann S, Rosenberg SA (eds) Lippincott-Raven Publisher, Philadelphia, pp 57-65
14. Harley CB, Futcher AB, Greider CW (1990) Telomeres shorten during ageing of human fibroblasts. Nature 343:458-460
15. Hastie ND, Dempster M, Dunlop MG, Thompson AM, Green DK, Allshire RC (1990) Telomere reduction in human colorectal carcinoma and ageing. Nature 346:866-868
16. Heine B, Hummel M, Müller M, Heicapell R, Miller K, Stein H (1998) Non-radioactive measurement of telomerase activity in human bladder cancer, bladder washings, and in urine. J Pathol 184:71-76
17. Hiyama E, Yokoyama T, Tatsumoto N, Hiyama K, Imamura Y, Murakami Y, Kodama T, Piatyszek MA, Shay JW, Matsuura Y (1995a) Telomerase activity in gastric cancer. Cancer Res 55:3258-262
18. Hiyama E, Hiyama K, Yokohama T, Matsuura Y, Piatyszek MA, Shay JW (1995b) Correlating telomerase activity levels with human neuroblastoma outcomes. Nat Med 1:249-255
19. Hiyama E, Gollahon L, Kataoka T, Kuroi K, Yokohama T, Gazdar AF, Hiyama K, Piatyszek MA, Shay JW (1996) Telomerase activity in human breast tumors. J Natl Cancer Inst 88:116-122
20. Holt SE, Wright SE, Shay JW (1996) Regulation of telomerase activity in immortal cell lines. Mol Cell Biol 16:2932-2939
21. Hoos A, Hepp HH, Kaul S, Ahlert T, Bastert G, Wallwiener D (1998) Telomerase activity correlates with tumor aggressiveness and reflects therapy effect in breast cancer. Int J Cancer (Pred Oncol) 79:8-12
22. Jacob K, Bosserhoff AK, Wach F, Knüchel R, Klein E, Hein R, Buettner R (1995) Characterization of selected strongly and weakly invasive sublines of a primary human melanoma cell line and isolation of subtractive cDNA clones. Int J Cancer 60:668-675
23. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PLC, Coviello GM, Wright WE, Weinrich SL, Shay JW (1994) Specific association of human telomerase activity with immortal cells and cancer. Science 266:2011-2014
24. Kyo S, Takakura M, Ishikawa H, Sasagawa T, Satake S, Tateno M, Inoue M (1997) Application of telomerase assay for the screening of cervical lesions. Cancer Res 57:1863-1867
25. Lange T de (1995) Telomere dynamics and genomic instability in human cancer. In: Blackburn EH, Greider CW (eds) Telomeres. Cold Spring Harbor Laboratory, Cold Spring Harbor, pp 265-293
26. Lange T de, Shiue L, Myers R, Cox DR, Naylor SL, Killery AM, Varmus HE (1990) Structure and variability of human chromo-some ends. Mol Cell Biol 10:518-527
27. Li ZH, Salovaara R, Aaltonen LA, Shibata D (1996) Telomerase activity is commonly detected in hereditary nonpolyposis colorectal cancers. Am J Pathol 148:1075-1079
28. Morin GB (1995) Is telomerase a universal cancer target? J Natl Cancer Inst 87:859-861
29. Müller M, Heine B, Heicapell R, Emrich T, Hummel M, Stein H, Miller K (1996) Telomerase activity in bladder cancer, bladder washings and in urine. Int J Oncol 9:1169-1173
30. Mutirangura A, Supiyaphun P, Trirekapan S, Sriuranpong V, Sakuntabhai A, Yenrudi S, Voravud N (1996) Telomerase activity in oral leukoplakia and head and neck squamous cell carcinoma. Cancer Res 56:3530-3533
31. Nouso K, Urabe Y, Higashi T, Nakatsukasa H, Hino N, Ashida K, Kinugasa N, Yoshida K, Uematsu S, Tsuji T (1996) Telomerase as a tool for the differential diagnosis of human hepatocellular carcinoma. Cancer 78:232-236
32. Ogoshi M, Takashima A, Taylor RS (1997) Mechanisms regulating telomerase activity in murine T cells. J Immunol 158:622-628
33. Ogoshi M, Le T, Shay JW, Taylor RS (1998) In situ hybridization analysis of the expression of human telomerase RNA in normal and pathologic conditions of the skin. J Invest Dermatol 110:818-823
34. Parkinson EK (1996) Do telomerase antagonists represent a novel anti-cancer strategy? Br J Cancer 73:1-4
35. Poremba C, Yandell DW, Metze D, Kamanabrou D, Bocker W, Dockhorn-Dworniczak B (1995) Immunohistochemical detection of p53 in melanomas with rare p53 gene mutations is associated with mdm-2 overexpression. Oncol Res 7:331-339
36. Pritchard ML, Woosley JT (1995) Comparison of two prognostic models predicting survival in patients with malignant melanoma. Hum Pathol 26:1028-1031
37. Rhyu MS (1995) Telomeres, telomerase, and immortality. J Natl Cancer Inst 87:884-894
38. Shay JW, Wright WE (1996) Telomerase activity in human cancer. Curr Opin Oncol 8:66-71
39. Sommerfeld HJ, Meeker AK, Piatyszek MA, Bova GS, Shay JW, Coffey DS (1996) Telomerase activity: a prevalent marker of malignant human prostate tissue. Cancer Res 56:218-222
40. Stolz W, Riemann A, Cognetta AB, Pillet L, Abmayr W, Hölzel D, Bilek P, Nachbar F, Landthaler M, Braun-Falco O (1994) ABCD rule of dermatoscopy: a new practical method for early recognition of malignant melanoma. Eur J Dermatol 7:521-528
41. Tahara H, Kuniyasu H, Yokozaki H, Yasui W, Shay JW, Ide T, Tahara E (1995) Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions. Clin Cancer Res 1:1245-1251
42. Taylor RS, Ramirez RD, Ogoshi M, Chaffins M, Piatyszek MA, Shay JW (1996) Detection of telomerase activity in malignant and nonmalignant skin conditions. J Invest Dermatol 106:759-765
43. Ueda M, Ouhtit A, Bito T, Nakazawa K, Lübbe J, Ichihashi M, Yamasaki H, Nakazawa H (1997) Evidence for UV-associated activation of telomerase in human skin. Cancer Res 57:370-374
44. Wright WE, Piatyszek MA, Rainey WE, Byrd W, Shay JW (1996) Telomerase activity in human germline and embryonic tissues and cells. Dev Genet 18:173-179
45. Yashima K, Milchgrub S, Gollahon LS, Maitra A, Saboorian MH, Shay JW, Gazdar AF (1998) Telomerase enzyme activity and RNA expression during the multistage pathogenesis of breast carcinoma. Clin Cancer Res 4:229-234
46. Yasumoto S, Kunimura C, Kikuchi K, Tahara H, Ohji H, Yamamoto H, Ide T, Utakoji T (1996) Telomerase activity in normal human epithelial cells. Oncogene 13:433-439
47. Yoshida K, Sugino T, Tahara H, Woodman A, Bolodeoku J, Nargund V, Fellows G, Goodison S, Tahara E, Tarin D (1997) Telomerase activity in bladder carcinoma and its implication for noninvasive diagnosis by detection of exfoliated cancer cells in urine. Cancer 79:362-369
48. Zakian VA (1995) Telomeres: beginning to understand the end. Science 270:1601-1607