IgG-secreting lymphoplasmacytoid leukaemia: A B-cell disorder with extensively mutated V(H) genes undergoing Ig isotype-switching frequently associated with trisomy 12

British Journal of Haematology

Volumn 109, Issue 1, 2000, Pages 71-80

  Garand, Richard ^a   Sahota, Surinder S ^b   Avet Loiseau, Hervé ^a   Talmant, Pascaline ^a   Robillard, Nelly ^a   Moreau, Anne ^c   Gaillard, Fanny ^c   Stevenson, Freda K ^b   Bataille, Régis ^a  

^a NANTES UNIVERSITY HOSPITAL   (France)

^b UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^c HÔTEL DIEU   (France)

Author keywords

Chronic B cell leukaemia; Cytogenetic diagnosis; Immunoglobin gene somatic mutation; Lymphoplasmacytoid lymphoma; Monoclonal gammopathy

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ADULT; AGED; ARTICLE; B CELL LEUKEMIA; CANCER SURVIVAL; CELL MATURATION; CHROMOSOME ANALYSIS; CLINICAL ARTICLE; CLINICAL FEATURE; FEMALE; GENE MUTATION; GENETIC ANALYSIS; HISTOPATHOLOGY; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; IMMUNOPHENOTYPING; LEUKEMOGENESIS; MALE; MEMORY CELL; MONOCLONAL IMMUNOGLOBULINEMIA; MULTIPLE MYELOMA; PRIORITY JOURNAL; SPLEEN DISEASE; TRISOMY 12;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; BASE SEQUENCE; CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 13; CYTOGENETIC ANALYSIS; FEMALE; GENE DELETION; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN G; IMMUNOPHENOTYPING; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, B-CELL, CHRONIC; LEUKEMIA, PLASMACYTIC; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; TRISOMY;

EID: 0034033744     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2000.01971.x     Document Type: Article

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