메뉴 건너뛰기




Volumn 12, Issue 2, 2000, Pages 159-165

To be or not to be a pro-T?

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR; GROWTH FACTOR RECEPTOR; HELIX LOOP HELIX PROTEIN; NOTCH RECEPTOR; TRANSCRIPTION FACTOR;

EID: 0034010697     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(99)00066-7     Document Type: Review
Times cited : (26)

References (48)
  • 1
    • 0028122624 scopus 로고
    • Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization
    • Rodewald H.R., Kretzschmar K., Takeda S., Hohl C., Dessing M. Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization. EMBO J. 13:1994;4229-4240.
    • (1994) EMBO J , vol.13 , pp. 4229-4240
    • Rodewald, H.R.1    Kretzschmar, K.2    Takeda, S.3    Hohl, C.4    Dessing, M.5
  • 2
    • 0032135207 scopus 로고    scopus 로고
    • Requirement for the thymus in αβ T lymphocyte lineage commitment
    • Carlyle J.R., Zuniga-Pflucker J.C. Requirement for the thymus in αβ T lymphocyte lineage commitment. Immunity. 9:1998;187-197.
    • (1998) Immunity , vol.9 , pp. 187-197
    • Carlyle, J.R.1    Zuniga-Pflucker, J.C.2
  • 3
    • 0029962079 scopus 로고    scopus 로고
    • Early T lymphocyte progenitors
    • Shortman K., Wu L. Early T lymphocyte progenitors. Annu Rev Immunol. 14:1996;29-47.
    • (1996) Annu Rev Immunol , vol.14 , pp. 29-47
    • Shortman, K.1    Wu, L.2
  • 4
    • 0027153201 scopus 로고
    • A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
    • Godfrey D.I., Kennedy J., Suda T., Zlotnik A. A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J Immunol. 150:1993;4244-4252.
    • (1993) J Immunol , vol.150 , pp. 4244-4252
    • Godfrey, D.I.1    Kennedy, J.2    Suda, T.3    Zlotnik, A.4
  • 5
    • 0031956471 scopus 로고    scopus 로고
    • In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development
    • Di Santo J.P., Rodewald H.R. In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development. Curr Opin Immunol. 10:1998;196-207.
    • (1998) Curr Opin Immunol , vol.10 , pp. 196-207
    • Di Santo, J.P.1    Rodewald, H.R.2
  • 6
    • 0032514764 scopus 로고    scopus 로고
    • Kinetics of T cell receptor β, γ, and δ rearrangements during adult thymic development: T cell receptor rearrangements are present in CD44(+)CD25(+) pro-T thymocytes
    • Capone M., Hockett R.D. Jr., Zlotnik A. Kinetics of T cell receptor β, γ, and δ rearrangements during adult thymic development: T cell receptor rearrangements are present in CD44(+)CD25(+) pro-T thymocytes. Proc Natl Acad Sci USA. 95:1998;12522-12527.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12522-12527
    • Capone, M.1    Hockett, R.d.jr.2    Zlotnik, A.3
  • 8
    • 0032969001 scopus 로고    scopus 로고
    • Transcriptional regulation of T lymphocyte development and function
    • Kuo C.T., Leiden J.M. Transcriptional regulation of T lymphocyte development and function. Annu Rev Immunol. 17:1999;149-187.
    • (1999) Annu Rev Immunol , vol.17 , pp. 149-187
    • Kuo, C.T.1    Leiden, J.M.2
  • 9
    • 0032235397 scopus 로고    scopus 로고
    • Structural conservation of Notch receptors and ligands
    • Fleming R.J. Structural conservation of Notch receptors and ligands. Semin Cell Dev Biol. 9:1998;599-607.
    • (1998) Semin Cell Dev Biol , vol.9 , pp. 599-607
    • Fleming, R.J.1
  • 10
    • 0033561454 scopus 로고    scopus 로고
    • Notch as a mediator of cell fate determination in hematopoiesis: Evidence and speculation
    • A comprehensive review on Notch biology in hematopoiesis.
    • Milner L.A., Bigas A. Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation. Blood. 93:1999;2431-2448. A comprehensive review on Notch biology in hematopoiesis.
    • (1999) Blood , vol.93 , pp. 2431-2448
    • Milner, L.A.1    Bigas, A.2
  • 11
    • 0032695278 scopus 로고    scopus 로고
    • Arbiter of differentiation and death: Notch signaling meets apoptosis
    • Miele L., Osborne B. Arbiter of differentiation and death: Notch signaling meets apoptosis. J Cell Physiol. 181:1999;393-409.
    • (1999) J Cell Physiol , vol.181 , pp. 393-409
    • Miele, L.1    Osborne, B.2
  • 12
    • 0032798711 scopus 로고    scopus 로고
    • Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: Distinct ligand-receptor interactions in intrathymic T cell development
    • Felli M.P., Maroder M., Mitsiadis T.A., Campese A.F., Bellavia D., Vacca A., Mann R.S., Frati L., Lendahl U., Gulino A., Screpanti I. Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development. Int Immunol. 11:1999;1017-1025.
    • (1999) Int Immunol , vol.11 , pp. 1017-1025
    • Felli, M.P.1    Maroder, M.2    Mitsiadis, T.A.3    Campese, A.F.4    Bellavia, D.5    Vacca, A.6    Mann, R.S.7    Frati, L.8    Lendahl, U.9    Gulino, A.10    Screpanti, I.11
  • 13
    • 0032968707 scopus 로고    scopus 로고
    • Regulation of T cell fate by Notch
    • Robey E. Regulation of T cell fate by Notch. Annu Rev Immunol. 17:1999;283-295.
    • (1999) Annu Rev Immunol , vol.17 , pp. 283-295
    • Robey, E.1
  • 14
    • 0028989016 scopus 로고
    • Notch1 is required for the coordinate segmentation of somites
    • Conlon R.A., Reaume A.G., Rossant J. Notch1 is required for the coordinate segmentation of somites. Development. 121:1995;1533-1545.
    • (1995) Development , vol.121 , pp. 1533-1545
    • Conlon, R.A.1    Reaume, A.G.2    Rossant, J.3
  • 15
    • 0032868937 scopus 로고    scopus 로고
    • Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality
    • Hamada Y., Kadokawa Y., Okabe M., Ikawa M., Coleman J.R., Tsujimoto Y. Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. Development. 126:1999;3415-3424.
    • (1999) Development , vol.126 , pp. 3415-3424
    • Hamada, Y.1    Kadokawa, Y.2    Okabe, M.3    Ikawa, M.4    Coleman, J.R.5    Tsujimoto, Y.6
  • 17
    • 0033136717 scopus 로고    scopus 로고
    • Deficient T cell fate specification in mice with an induced inactivation of Notch1
    • ••], demonstrates the essential role of Notch1 signaling in specifying T lineage development. Remarkably, all other hematopoietic lineages appear unaffected by Notch1-deficiency.
    • ••], demonstrates the essential role of Notch1 signaling in specifying T lineage development. Remarkably, all other hematopoietic lineages appear unaffected by Notch1-deficiency.
    • (1999) Immunity , vol.10 , pp. 547-558
    • Radtke, F.1    Wilson, A.2    Stark, G.3    Bauer, M.4    Van Meerwijk, J.5    MacDonald, H.R.6    Aguet, M.7
  • 18
    • 0030831130 scopus 로고    scopus 로고
    • Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    • Kondo M., Weissman I.L., Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell. 91:1997;661-672.
    • (1997) Cell , vol.91 , pp. 661-672
    • Kondo, M.1    Weissman, I.L.2    Akashi, K.3
  • 19
    • 0029828994 scopus 로고    scopus 로고
    • Transcription factor GATA-3 is required for development of the T-cell lineage
    • Ting C.N., Olson M.C., Barton K.P., Leiden J.M. Transcription factor GATA-3 is required for development of the T-cell lineage. Nature. 384:1996;474-478.
    • (1996) Nature , vol.384 , pp. 474-478
    • Ting, C.N.1    Olson, M.C.2    Barton, K.P.3    Leiden, J.M.4
  • 20
    • 0032992351 scopus 로고    scopus 로고
    • Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus
    • Using 'knock-in' of a LacZ reporter gene into the GATA-3 locus, these authors demonstrate that GATA-3 deficiency abolishes the development of the earliest thymocyte precursors and GATA-3 expression appears to be linked to the cell cycle.
    • Hendriks R.W., Nawijn M.C., Engel J.D., van Doorninck H., Grosveld F., Karis A. Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus. Eur J Immunol. 29:1999;1912-1918. Using 'knock-in' of a LacZ reporter gene into the GATA-3 locus, these authors demonstrate that GATA-3 deficiency abolishes the development of the earliest thymocyte precursors and GATA-3 expression appears to be linked to the cell cycle.
    • (1999) Eur J Immunol , vol.29 , pp. 1912-1918
    • Hendriks, R.W.1    Nawijn, M.C.2    Engel, J.D.3    Van Doorninck, H.4    Grosveld, F.5    Karis, A.6
  • 21
    • 0031963681 scopus 로고    scopus 로고
    • Id helix-loop-helix proteins in cell growth and differentiation
    • A concise review of bHLH activators and inhibitors and their molecular mechanisms of action.
    • Norton J.D., Deed R.W., Craggs G., Sablitzky F. Id helix-loop-helix proteins in cell growth and differentiation. Trends Cell Biol. 8:1998;58-65. A concise review of bHLH activators and inhibitors and their molecular mechanisms of action.
    • (1998) Trends Cell Biol , vol.8 , pp. 58-65
    • Norton, J.D.1    Deed, R.W.2    Craggs, G.3    Sablitzky, F.4
  • 22
    • 0033193157 scopus 로고    scopus 로고
    • The Notch-Hes pathway in mammalian neural development
    • Kageyama R., Ohtsuka T. The Notch-Hes pathway in mammalian neural development. Cell Res. 9:1999;179-188.
    • (1999) Cell Res , vol.9 , pp. 179-188
    • Kageyama, R.1    Ohtsuka, T.2
  • 23
    • 0033135269 scopus 로고    scopus 로고
    • The bHLH gene Hes1 is essential for expansion of early T cell precursors
    • The first demonstration of an essential role for Hes1 in thymocyte development.
    • Tomita K., Hattori M., Nakamura E., Nakanishi S., Minato N., Kageyama R. The bHLH gene Hes1 is essential for expansion of early T cell precursors. Genes Dev. 13:1999;1203-1210. The first demonstration of an essential role for Hes1 in thymocyte development.
    • (1999) Genes Dev , vol.13 , pp. 1203-1210
    • Tomita, K.1    Hattori, M.2    Nakamura, E.3    Nakanishi, S.4    Minato, N.5    Kageyama, R.6
  • 24
    • 0032053253 scopus 로고    scopus 로고
    • The role of E-proteins in B- And T-lymphocyte development
    • Bain G., Murre C. The role of E-proteins in B- and T-lymphocyte development. Semin Immunol. 10:1998;143-153.
    • (1998) Semin Immunol , vol.10 , pp. 143-153
    • Bain, G.1    Murre, C.2
  • 26
    • 0033568023 scopus 로고    scopus 로고
    • A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during αβ thymopoiesis
    • With [25] this work defines a role for bHLH transcription factors in early thymocyte development.
    • Barndt R., Dai M.F., Zhuang Y. A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during αβ thymopoiesis. J Immunol. 163:1999;3331-3343. With [25] this work defines a role for bHLH transcription factors in early thymocyte development.
    • (1999) J Immunol , vol.163 , pp. 3331-3343
    • Barndt, R.1    Dai, M.F.2    Zhuang, Y.3
  • 27
    • 0033577695 scopus 로고    scopus 로고
    • Disruption of αβ but not of γδ T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors
    • The authors demonstrate that Id3 can modulate the development of distinct T cell lineages, which suggests that Id proteins might have a role in T cell commitment.
    • Blom B., Heemskerk M.H., Verschuren M.C., van Dongen J.J., Stegmann A.P., Bakker A.Q., Couwenberg F., Res P.C., Spits H. Disruption of αβ but not of γδ T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors. EMBO J. 18:1999;2793-2802. The authors demonstrate that Id3 can modulate the development of distinct T cell lineages, which suggests that Id proteins might have a role in T cell commitment.
    • (1999) EMBO J , vol.18 , pp. 2793-2802
    • Blom, B.1    Heemskerk, M.H.2    Verschuren, M.C.3    Van Dongen, J.J.4    Stegmann, A.P.5    Bakker, A.Q.6    Couwenberg, F.7    Res, P.C.8    Spits, H.9
  • 28
    • 0030666853 scopus 로고    scopus 로고
    • High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice
    • Yan W., Young A.Z., Soares V.C., Kelley R., Benezra R., Zhuang Y. High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice. Mol Cell Biol. 17:1997;7317-7327.
    • (1997) Mol Cell Biol , vol.17 , pp. 7317-7327
    • Yan, W.1    Young, A.Z.2    Soares, V.C.3    Kelley, R.4    Benezra, R.5    Zhuang, Y.6
  • 29
    • 0033602163 scopus 로고    scopus 로고
    • Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2
    • First demonstration of an essential role for Id proteins in lymphoid development.
    • Yokota Y., Mansouri A., Mori S., Sugawara S., Adachi S., Nishikawa S., Gruss P. Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature. 397:1999;702-706. First demonstration of an essential role for Id proteins in lymphoid development.
    • (1999) Nature , vol.397 , pp. 702-706
    • Yokota, Y.1    Mansouri, A.2    Mori, S.3    Sugawara, S.4    Adachi, S.5    Nishikawa, S.6    Gruss, P.7
  • 30
    • 0032766646 scopus 로고    scopus 로고
    • Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene
    • These authors show that different Id proteins can functionally compensate for each other within certain lymphoid lineages.
    • Pan L., Sato S., Frederick J.P., Sun X.H., Zhuang Y. Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene. Mol Cell Biol. 19:1999;5969-5980. These authors show that different Id proteins can functionally compensate for each other within certain lymphoid lineages.
    • (1999) Mol Cell Biol , vol.19 , pp. 5969-5980
    • Pan, L.1    Sato, S.2    Frederick, J.P.3    Sun, X.H.4    Zhuang, Y.5
  • 31
    • 0030665673 scopus 로고    scopus 로고
    • Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3
    • Heemskerk M.H., Blom B., Nolan G., Stegmann A.P., Bakker A.Q., Weijer K., Res P.C., Spits H. Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3. J Exp Med. 186:1997;1597-1602.
    • (1997) J Exp Med , vol.186 , pp. 1597-1602
    • Heemskerk, M.H.1    Blom, B.2    Nolan, G.3    Stegmann, A.P.4    Bakker, A.Q.5    Weijer, K.6    Res, P.C.7    Spits, H.8
  • 32
    • 0029065488 scopus 로고
    • Crucial role of the pre-T-cell receptor α gene in development of αβ but not γδ T cells
    • Fehling H.J., Krotkova A., Saint-Ruf C., von Boehmer H. Crucial role of the pre-T-cell receptor α gene in development of αβ but not γδ T cells. Nature. 375:1995;795-798.
    • (1995) Nature , vol.375 , pp. 795-798
    • Fehling, H.J.1    Krotkova, A.2    Saint-Ruf, C.3    Von Boehmer, H.4
  • 33
    • 0031985410 scopus 로고    scopus 로고
    • Natural killer cell development and function precede αβ T cell differentiation in mouse fetal thymic ontogeny
    • Carlyle J.R., Michie A.M., Cho S.K., Zuniga-Pflucker J.C. Natural killer cell development and function precede αβ T cell differentiation in mouse fetal thymic ontogeny. J Immunol. 160:1998;744-753.
    • (1998) J Immunol , vol.160 , pp. 744-753
    • Carlyle, J.R.1    Michie, A.M.2    Cho, S.K.3    Zuniga-Pflucker, J.C.4
  • 34
    • 0032211699 scopus 로고    scopus 로고
    • IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
    • First in vivo demonstration that NK cell development is uniquely dependent on IL-15 receptor signaling.
    • Lodolce J.P., Boone D.L., Chai S., Swain R.E., Dassopoulos T., Trettin S., Ma A. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity. 9:1998;669-676. First in vivo demonstration that NK cell development is uniquely dependent on IL-15 receptor signaling.
    • (1998) Immunity , vol.9 , pp. 669-676
    • Lodolce, J.P.1    Boone, D.L.2    Chai, S.3    Swain, R.E.4    Dassopoulos, T.5    Trettin, S.6    Ma, A.7
  • 35
    • 0030726968 scopus 로고    scopus 로고
    • The common cytokine receptor gamma chain controls survival of γ/δ T cells
    • Malissen M., Pereira P., Gerber D.J., Malissen B., Di Santo J.P. The common cytokine receptor gamma chain controls survival of γ/δ T cells. J Exp Med. 186:1997;1277-1285.
    • (1997) J Exp Med , vol.186 , pp. 1277-1285
    • Malissen, M.1    Pereira, P.2    Gerber, D.J.3    Malissen, B.4    Di Santo, J.P.5
  • 36
    • 0033523613 scopus 로고    scopus 로고
    • Defective development of γ/δ T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor γ genes
    • Kang J., Coles M., Raulet D.H. Defective development of γ/δ T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor γ genes. J Exp Med. 190:1999;973-982.
    • (1999) J Exp Med , vol.190 , pp. 973-982
    • Kang, J.1    Coles, M.2    Raulet, D.H.3
  • 37
    • 0030978529 scopus 로고    scopus 로고
    • Pro-thymocyte expansion by c-kit and the common cytokine receptor γ chain is essential for repertoire formation
    • Rodewald H.R., Ogawa M., Haller C., Waskow C., Di Santo J.P. Pro-thymocyte expansion by c-kit and the common cytokine receptor γ chain is essential for repertoire formation. Immunity. 6:1997;265-272.
    • (1997) Immunity , vol.6 , pp. 265-272
    • Rodewald, H.R.1    Ogawa, M.2    Haller, C.3    Waskow, C.4    Di Santo, J.P.5
  • 38
    • 0033592897 scopus 로고    scopus 로고
    • Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant mice
    • c double-mutant mice, which manifest a complete absence of all thymocyte lineages but develop thymic dendritic cells, calls into question the requirement for early thymocyte precursors in the generation of these cells.
    • c double-mutant mice, which manifest a complete absence of all thymocyte lineages but develop thymic dendritic cells, calls into question the requirement for early thymocyte precursors in the generation of these cells.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 15068-15073
    • Rodewald, H.R.1    Brocker, T.2    Haller, C.3
  • 39
    • 0033081225 scopus 로고    scopus 로고
    • The common cytokine receptor γ chain and the pre-T cell receptor provide independent but critically overlapping signals in early α/β T cell development
    • Di Santo J.P., Aifantis I., Rosmaraki E., Garcia C., Feinberg J., Fehling H.J., Fischer A., von Boehmer H., Rocha B. The common cytokine receptor γ chain and the pre-T cell receptor provide independent but critically overlapping signals in early α/β T cell development. J Exp Med. 189:1999;563-574.
    • (1999) J Exp Med , vol.189 , pp. 563-574
    • Di Santo, J.P.1    Aifantis, I.2    Rosmaraki, E.3    Garcia, C.4    Feinberg, J.5    Fehling, H.J.6    Fischer, A.7    Von Boehmer, H.8    Rocha, B.9
  • 40
    • 0032442040 scopus 로고    scopus 로고
    • Correlating notch signaling with thymocyte maturation
    • Deftos M.L., He Y.W., Ojala E.W., Bevan M.J. Correlating notch signaling with thymocyte maturation. Immunity. 9:1998;777-786.
    • (1998) Immunity , vol.9 , pp. 777-786
    • Deftos, M.L.1    He, Y.W.2    Ojala, E.W.3    Bevan, M.J.4
  • 42
    • 0032479989 scopus 로고    scopus 로고
    • PU.1 regulates both cytokine dependent proliferation and differentiation of granulocyte/ macrophage progenitors
    • Demonstration that one mechanism by which PU.1 affects myeloid differentiation is via maintenance of cytokine and growth factor receptor expression.
    • DeKoter R.P., Walsh J.C., Singh H. PU.1 regulates both cytokine dependent proliferation and differentiation of granulocyte/ macrophage progenitors. EMBO J. 17:1998;4456-4468. Demonstration that one mechanism by which PU.1 affects myeloid differentiation is via maintenance of cytokine and growth factor receptor expression.
    • (1998) EMBO J , vol.17 , pp. 4456-4468
    • Dekoter, R.P.1    Walsh, J.C.2    Singh, H.3
  • 43
    • 0342357986 scopus 로고    scopus 로고
    • PU.1 regulates proliferation and differentiation of B cell progenitors by controlling expression of the IL-7 receptor
    • B. Stillman. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory. [abstract]
    • DeKoter R.P. PU.1 regulates proliferation and differentiation of B cell progenitors by controlling expression of the IL-7 receptor. Stillman B. Signaling and Gene Expression in the Immune System. 1999;47 Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. [abstract].
    • (1999) Signaling and Gene Expression in the Immune System , pp. 47
    • Dekoter, R.P.1
  • 44
    • 0033214311 scopus 로고    scopus 로고
    • PU.1 and the granulocyte- And macrophage colony-stimulating factor receptors play distinct roles in late-stage myeloid cell differentiation
    • Anderson K.L., Smith K.A., Perkin H., Hermanson G., Anderson C.G., Jolly D.J., Maki R.A., Torbett B.E. PU.1 and the granulocyte- and macrophage colony-stimulating factor receptors play distinct roles in late-stage myeloid cell differentiation. Blood. 94:1999;2310-2318.
    • (1999) Blood , vol.94 , pp. 2310-2318
    • Anderson, K.L.1    Smith, K.A.2    Perkin, H.3    Hermanson, G.4    Anderson, C.G.5    Jolly, D.J.6    Maki, R.A.7    Torbett, B.E.8
  • 45
    • 0033197967 scopus 로고    scopus 로고
    • T cell development in PU.1-deficient mice
    • Demonstration that PU.1 deficiency affects the development of the earliest thymocyte precursors possibly through reduced expression of the c-kit receptor gene.
    • Spain L.M., Guerriero A., Kunjibettu S., Scott E.W. T cell development in PU.1-deficient mice. J Immunol. 163:1999;2681-2687. Demonstration that PU.1 deficiency affects the development of the earliest thymocyte precursors possibly through reduced expression of the c-kit receptor gene.
    • (1999) J Immunol , vol.163 , pp. 2681-2687
    • Spain, L.M.1    Guerriero, A.2    Kunjibettu, S.3    Scott, E.W.4
  • 46
    • 0028804041 scopus 로고
    • Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo
    • Rodewald H.R., Kretzschmar K., Swat W., Takeda S. Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo. Immunity. 3:1995;313-319.
    • (1995) Immunity , vol.3 , pp. 313-319
    • Rodewald, H.R.1    Kretzschmar, K.2    Swat, W.3    Takeda, S.4
  • 47
    • 0032784934 scopus 로고    scopus 로고
    • Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage
    • A comprehensive study of expression of Ets family TFs in the thymus and a stimulating discussion of their implications for T cell development.
    • Anderson M.K., Hernandez-Hoyos G., Diamond R.A., Rothenberg E.V. Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage. Development. 126:1999;3131-3148. A comprehensive study of expression of Ets family TFs in the thymus and a stimulating discussion of their implications for T cell development.
    • (1999) Development , vol.126 , pp. 3131-3148
    • Anderson, M.K.1    Hernandez-Hoyos, G.2    Diamond, R.A.3    Rothenberg, E.V.4
  • 48
    • 0033578019 scopus 로고    scopus 로고
    • Inhibition of Rho at different stages of thymocyte development gives different perspectives on Rho function
    • Cleverley S., Henning S., Cantrell D. Inhibition of Rho at different stages of thymocyte development gives different perspectives on Rho function. Curr Biol. 9:1999;657-660.
    • (1999) Curr Biol , vol.9 , pp. 657-660
    • Cleverley, S.1    Henning, S.2    Cantrell, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.