In vitro growth-inhibitory activity of pneumocandins L-733,560 and L-743,872 against putatively amphotericin B- and fluconazole-resistant Candida isolates: Influence of assay conditions

Medical Mycology

Volumn 35, Issue 4, 1997, Pages 285-287

  Nelson, P W ^a   Lozano Chiu, M ^a   Rex, J H ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

amphotericin B; antifungal susceptibility testing; fluconazole; pneumocandin

Indexed keywords

AMPHOTERICIN B; CASPOFUNGIN; FLUCONAZOLE; L 733560; PNEUMOCANDIN DERIVATIVE;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA; CONCENTRATION RESPONSE; CONTROLLED STUDY; FUNGUS CULTURE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN;

AMPHOTERICIN B; ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTIFUNGAL; ANTIFUNGAL AGENTS; CANDIDA; DRUG RESISTANCE, MICROBIAL; FLUCONAZOLE; HUMANS; MICROBIAL SENSITIVITY TESTS; PEPTIDES; PEPTIDES, CYCLIC;

CANDIDA; FUNGI;

EID: 80051502274     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.1080/02681219780001291     Document Type: Article

References (10)

1. Abruzzo GK, Flattery AM, Gill CJ, et al. Evaluation of water-soluble pneumocandin analogs L-733560, L-705589 and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis. Antimicrob Agents Chemother 1995; 39: 1077-81.
2. Bartizal K, Scott T, Abruzzo GK, et al. In vitro evaluation of the pneumocandin antifungal agent L-733560, a new water-soluble hybrid of L-705589 and L-731373. Antimicrob Agents Chemother 1995; 39: 1070-6.
3. Martinez-Suarez JV, Rodriguez-Tudela JL. In vitro activities of semisynthetic pneumocandin L-733,560 against fluconazole-resistant and -susceptible Candida albicans isolates. Antimicrob Agents Chemother 1996; 40: 1277-9. (Pubitemid 26136050)
4. National Committee for Clinical Laboratory Standards. Reference method for broth dilution antifungal susceptibility testing of yeasts; tentative standard. M27-T. Wayne, Pa: National Committee for Clinical Laboratory Standards, 1995.
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7. Wanger A, Mills K, Nelson PW, Rex JH. Comparison of Etest and National Committee for Clinical Laboratory Standards broth macrodilution method for antifungal susceptibility testing: enhanced ability to detect amphotericin B-resistant Candida isolates. Antimicrob Agents Chemother 1995; 39: 2520-2.
8. Rex JH, Pfaller MA, Barry AL, Nelson PW, Webb CD, the NIAID Mycoses Study Group and the Candidemia Study Group. Antifungal susceptibility testing of isolates from a randomized, multicenter trial of fluconazole versus amphotericin B as treatment of nonneutropenic patients with candidemia. Antimicrob Agents Chemother 1995; 39: 40-4.
9. Rex JH, Pfaller MA, Galgiani JN, et al. Development of interpretive breakpoints for antifungal susceptibility testing: conceptual framework and analysis of in vitro-in vivo correlation data for fluconazole, itraconazole and Candida infections. Clin Infect Dis 1997; 24: 235-49. (Pubitemid 27081549)
10. Lozano-Chiu M, Rex JH, Nelson PW. Lot-to-lot variability of Antibiotic Medium 3 (AM3) when used for susceptibility testing of Candida to amphotericin B (AmB) by M27P. In: Abstracts of the 96th General Meeting of the American Society for Microbiology, 1996, Abstract no. F84, p. 88. American Society for Microbiology, Washington, DC.