Ion tolerance of Saccharomyces cerevisiae lacking the Ca2+/CaM- dependent phosphatase (calcineurin) is improved by mutations in URE2 or PMA1

Genetics

Volumn 149, Issue 2, 1998, Pages 865-878

  Withee, James L ^a   Sen, Romita ^a   Cyert, Martha S ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CALCIUM ION; GLUTATHIONE TRANSFERASE; HYGROMYCIN B; LITHIUM ION; MANGANESE; PHEROMONE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM ION; TRANSCRIPTION FACTOR;

ANTIBIOTIC RESISTANCE; ARTICLE; CATION TRANSPORT; FUNGUS GROWTH; GENE EXPRESSION; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

ADENOSINE TRIPHOSPHATASES; CALCINEURIN; CALCIUM; CATION TRANSPORT PROTEINS; DNA-BINDING PROTEINS; DRUG RESISTANCE, MICROBIAL; ENZYME ACTIVATION; FUNGAL PROTEINS; GENES, FUNGAL; HOMEOSTASIS; HYDROGEN-ION CONCENTRATION; HYGROMYCIN B; ION TRANSPORT; LITHIUM; MANGANESE; MUTATION; PRIONS; PROTON-TRANSLOCATING ATPASES; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES POMBE PROTEINS; SODIUM; TRANSCRIPTION FACTORS;

EID: 0031748055     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (58)

1. 2+-permeable slow vacuolar ion channel of stomatal guard cells. Plant Cell 7: 1473-1483.
2. 2+-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution. Mol. Biol. Cell 3: 633-654.
3. AUSUBEL, F. M., R. BRENT, R. E. KINGSTON, D. D. MOORE, J. G. SEIDMAN et al., 1987 Current Protocols in Molecular Biology. John Wiley & Sons, New York.
4. 2+ flux. Cell 83: 463-472.
5. +]ATPase involves phosphorylation during intracellular transport. J. Cell Biol. 115: 289-295.
6. COSCHIGANO, P. W., and B. MAGASANIK, 1991 The URE2 gene product of Saccharomyces cerevisiae plays an important role in the cellular response to nitrogen source and has homology to glutathione S-transferases. Mol. Cell. Biol. 11: 822-832.
7. COURCHESNE, W. E., and B. MAGASANIK, 1988 Regulation of nitrogen assimilation in Saccaromyces cerevisiae: roles of the URE2 and GLN3. J. Bacteriol. 170: 708-713.
8. 2+ ATPases. J. Cell Biol. 124: 351-363.
9. 2+-ATPases in Saccharomyces cerevisiae. Mol. Cell. Biol. 16: 2226-2237.
10. NTRelements and activating transcription in Saccharomyces cerevisiae. J. Bacteriol. 178:3470-3479.
11. 2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone. Mol. Cell. Biol. 12: 3460-3469.
12. CYERT, M. S., R. KUNISAWA, D. KAIM and J. THORNER, 1991 Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase. Proc. Nat. Acad. Sci. USA 88: 7376-7380.
13. DRILLIEN, R., M. AIGLE and F. LACROUTE, 1973 Yeast mutants pleiotropically impaired in the regulation of two glutamate dehydrogenases. Biochem. Biophys. Res. Commun. 53: 367-372.
14. 2+ by yeast vacuoles. J. Biol. Chem. 269: 7273-7278.
15. ERASO, P., and C. GANSEDO, 1987 Activation of yeast plasma membrane ATPase by acid pH during growth. FEBS Lett. 224: 187-192.
16. FARCASANU, I. C., D. HIRATA, E. TSUCHIYA, F. NISHIYAMA and T. MIYAKAWA, 1995 Protein phosphatase 2B of Saccharomyces cerevisiae is required for tolerance to manganese in blocking the entry of ions into the cell. Eur. J. Biochem. 232: 712-717.
17. FERRANDO, A., S. J. KRON, G. RIOS, G. R. FINK and R. SERRANO, 1995 Regulation of cation transport in Saccharomyces cerevisiae by the salt tolerance gene HAL3. Mol. Cell. Biol. 15: 5470-5481.
18. GARCIADEBLAS, B., F. RUBIO, F. J. QUINTERO, M. A. BANUELOS, R. HARO et al., 1993 Differential expression of two genes encoding isoforms of the ATPase involved in sodium efflux in Saccharomyces cerevisiae. Mol. Gen. Genet. 236: 363-368.
19. GOFFEAU, A., and C. W. SLAYMAN, 1981 The proton-translocating ATPase of the fungal plasma membrane. Biochim. Biophys. Acta 639: 197-223.
20. HARO, R., B. GARCIADEBLAS and A. RODRIGUEZ-NAVARRO, 1991 A novel P-type ATPase from yeast involved in sodium transport. FEBS Lett. 291: 189-191.
21. HUBBARD, M. J., and C. B. KLEE, 1989 Functional domain structure of calcineurin A: mapping by limited proteolysis. Biochemistry 28: 1868-1874.
22. i rise in maintaining viability of yeast cells late in the mating pheromone response pathway. J. Biol. Chem. 265: 13391-13399.
23. KLEE, C. B., G. F. DRAETTA and M. J. HUBBARD, 1988 Calcineurin. Adv. Enzymol. 61: 149-200.
24. KOLAROV, J., J. KULPA, M. BAIJOT and A. GOFFEAU, 1988 Characterization of a protein serine kinase from yeast plasma membrane. J. Biol. Chem. 263: 10613-10619.
25. KUNO, T., H. TANAKA, J. MUKAI, C. CHANG, K. HIRAGA et al., 1991 cDNA cloning of a calcineurin B homolog in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 180: 1159-1163.
26. 2+- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils. Nature 377: 75-79.
27. 2+-dependent phosphatase. Nature 369: 235-239.
28. LINK, A. J., and M. V. OLSON, 1991 Physical map of the Saccharomyces cerevisiae genome at 110-kilobase resolution. Genetics 127: 681-698.
29. LIU, J., 1993 FK506 and cyclosporin, molecular probes for studying intracellular signal transduction. Immunol. Today 14: 290-295.
30. LIU, J., J. J. D. FARMER, W. L. LANE, J. FRIEDMAN, I. WEISSMAN et al., 1991a Calcineurin is a common target of cyclophilin-CsA and FKBP-FK506 complexes. Cell 66: 807-815.
31. LIU, Y., S. ISHII, M. TOKAI, H. TSUTSUMI, O. OHKE et al., 1991b The Saccharomyces cerevisiae genes (CMP1 and CMP2) encoding calmodulin-binding proteins homologous to the catalytic subunit of mammalian protein phosphatase 2B. Mol. Gen. Genet. 227: 52-59.
32. + channels in guard cells. Proc. Nat. Acad. Sci. USA 90: 2202-2206.
33. MATHEOS, D. P., T. J. KINGSBURY, U. S. AHSAN and K. W. CUNNINGHAM, 1997 Tcn1p/Crz1p, a calcineurin-dependent transcription factor that differentially regulates gene expression in Saccharomyces cerevisiae. Genes Dev. 11: 3445-3458.
34. MCCUSKER, J. H., D. PERLIN and J. E. HABER, 1987 Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae. Mol. Cell. Biol. 7: 4082-4088.
35. MENDOZA, I., F. RUBIO, A. RODRIGUEZ-NAVARRO and J. M. PARDO, 1994 The protein phosphatase calcineurin is essential for NaCl tolerance of Saccharomyces cerevisiae. J. Biol. Chem. 269: 8792-8796.
36. MINEHART, P. L., and B. MAGASANIK, 1991 Sequence and expression of GLN3, a positive nitrogen regulatory gene of Saccharomyces cerevisiae encoding a protein with a putative zinc finger DNA-binding domain. Mol. Cell. Biol. 11: 6216-6228.
37. 2+-calmodulin-dependent protein kinase. Mol. Cell. Biol. 16: 4824-4831.
38. NAKAMURA, T., Y. LIU, D. HIRATA, H. NAMBA, S. HARADA et al. 1993 Protein phosphatase type 2B (calcineurin)-mediated, FK506-sensitive regulation of intracellular ions in yeast is an important determinant for adaptation to high salt stress conditions. EMBO J. 12: 4063-4071.
39. + ATPase. J. Biol. Chem. 272: 26145-26152.
40. O'KEEFE, S. J., J. TAMURA, R. L. KINCAID, M. J. TOCCI and E. A. O'NEILL, 1992 FK506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin. Nature 357: 692-694.
41. OHSUMI, Y., and Y. ANRAKU, 1983 Calcium transport driven by a proton motive force in vacuolar membrane vesicles of Saccharomyces cerevisiae. J. Biol. Chem. 258: 5614-5617.
42. +-ATPase activity. J. Biol. Chem. 266: 13971-13977.
43. PERLIN, D., C. BROWN and J. E. HABER, 1988 Membrane potential defect in hygromycin B-resistant mutants of Saccharomyces cerevisiae. J. Biol. Chem. 263: 18118-18122.
44. PORTILLO, F., and R. SERRANO, 1989 Growth control strength and active site of yeast plasma membrane ATPase studied by site-directed mutagenesis. Eur. J. Biochem. 186: 501-507.
45. 2+ exchangers. Mol. Cell. Biol. 16: 3730-3741.
46. + ATPase. Yeast 9: 1075-1084.
47. SCHWANINGER, M., R. BLUME, E. OETJEN, G. LUX and W. KNEPEL, 1993 Inhibition of cAMP-responsive element-mediated gene transcription by cyclosporin A and FK506 after membrane depolarization. J. Biol. Chem. 268: 23111-23115.
48. SERRANO, R., 1983 In vivo glucose activation of the yeast plasma membrane ATPase. FEBS Lett. 156: 11-14.
49. SERRANO, R., 1984 Plasma membrane ATPase of fungi and plants as a novel type of proton pump. Curr. Topics Cell. Regul. 23: 87-126.
50. 2+ ATPase. Nature 319: 689-693.
51. SHERMAN, F., G. R. FINK and J. B. HICKS, 1986 Methods in Yeast Genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
52. SIKORSKI, R. S., and P. HIETER, 1989 A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
53. STATHOPOULOS, A. M., and M. S. CYERT, 1997 Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast. Genes Dev. 11: 3432-3444.
54. 2+ homeostasis of yeast cells. J. Biol. Chem. 270: 10113-10119.
55. TSIEN, R. W., and R. Y. TSIEN, 1991 Calcium channels, stores and oscillations. Ann. Rev. Cell Biol. 6: 715-760.
56. +-ATPase. Yeast 5: 307-319.
57. + pump in the yeast plasma membrane. EMBO J. 14: 3870-3882.
58. 2+ signal is to activate calcineurin. Mol. Biol. Cell 8: 263-277.