The immunosuppressant FK506 and its nonimmunosuppressive analog L- 685,818 are toxic to Cryptococcus neoformans by inhibition of a common target protein

Antimicrobial Agents and Chemotherapy

Volumn 41, Issue 1, 1997, Pages 156-161

  Odom, A ^a   Del Poeta, M ^a   Perfect, J ^a   Heitman, J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; CALCINEURIN; CYCLOSPORIN A; DRUG BINDING PROTEIN; IMMUNOSUPPRESSIVE AGENT; L 685818; TACROLIMUS; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFUNGAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DRUG RESISTANCE; DRUG TARGETING; FUNGAL MENINGITIS; FUNGUS GROWTH; FUNGUS MUTANT; IMMUNOSUPPRESSIVE TREATMENT; NONHUMAN; PRIORITY JOURNAL; RABBIT; TEMPERATURE DEPENDENCE;

EID: 0031028176     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.1.156     Document Type: Article

References (52)