Recent advances in cardiac hypertrophy

Cardiovascular Research

Volumn 45, Issue 1, 2000, Pages 68-75

  Olivetti, Giorgio ^a   Cigola, Elena ^a   Maestri, Roberta ^a   Lagrasta, Costanza ^a   Corradi, Demenico ^a   Quaini, Federico ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

Blood pressure; Hypertension; Hypertrophy; Renal function

Indexed keywords

AGING; CELL DEATH; CONGESTIVE HEART FAILURE; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; HUMAN; HYPERTENSION; NONHUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; REVIEW; STRESS;

ANIMALS; CARDIOMEGALY; HEART; HUMANS; MYOCARDIUM;

EID: 0033991616     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(99)00298-9     Document Type: Review

References (100)

1. Sen S., Tarazi R.C., Bumpus F.M. Cardiac hypertrophy and antihypertensive therapy. Cardiovasc Res. 11:1977;427-433.
2. Olivetti G., Giordano G., Corradi D., et al. Gender differences and aging: effects on the human heart. J Am Coll Cardiol. 26:1995;1068-1079.
3. de Simone G., Devereux R., Daniels S.R., et al. Effect of growth on variability of left ventricular mass: assessment of allometric signals in adults and children and their capacity to predict cardiovascular risk. J Am Coll Cardiol. 25:1995;1056-1062.
4. Anversa P., Ricci R., Olivetti G. Quantitative structural analysis of the myocardium during physiologic growth and induced cardiac hypertrophy: a review. J Am Coll Cardiol. 7:1986;1140-1149.
5. Sonnenblick E.H., Strobeck J.E., Capasso J.M., Factor S.M. Ventricular hypertrophy: models and methods. Tarazi R.C., Dunbar J.B. Perspectives in cardiovascular research. Cardiac hypertrophy in hypertension. 8:1983;13-20 Raven Press, New York.
6. Anversa P., Beghi C., Kikkawa Y., Olivetti G. Myocardial infarction in rats. Infarct size, myocyte hypertrophy, and capillary growth. Circ Res. 58:1986;26-37.
7. Spirito P., Seidman C., McKenna W.J., Maron B.J. The management of hypertrophic cardiomyopathy. N Engl J Med. 336:1997;775-785.
8. Schmieder R.E., Messerli F.H. Is the decrease in arterial pressure the sole factor for reduction of left ventricular hypertrophy. Am J Med. 92:1992;S28-S34.
9. Ghali J.K., Kadakia S., Cooper R.S., Liao Y. Impact of left ventricular hypertrophy on ventricular arrhythmias in the absence of coronary artery disease. J Am Coll Cardiol. 17:1991;1277-1282.
10. Liao Y., Cooper R.S., Mensah G.A., McGee D.L. Left ventricular hypertrophy has a greater impact on survival in women than in men. Circulation. 92:1995;805-810.
11. Linzbach A.J. Heart failure from the point of view of quantitative anatomy. Am J Cardiol. 5:1960;370-382.
12. Meerson F.Z. Insufficiency of hypertrophied heart. Basic Res Cardiol. 71:1976;343-354.
13. Braunwald E. Cardiovascular medicine at the turn of the millennium: triumphs, concerns, and opportunities. N Engl J Med. 337:1997;1360-1369.
14. Cleland J.G.S.K., Poole-Wilson P.A. Successes and failures of current treatment of heart failure. Lancet. 352:(suppl 1):1998;19-28.
15. Anversa P., Palackal T., Sonnenblick E.H., et al. Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart. Circ Res. 67:1990;871-885.
16. Carroll J.D., Carroll E.P., Feldman T., et al. Sex-associated differences in left ventricular function in aortic stenosis of the elderly. Circulation. 86:1992;1099-1107.
17. Aurigemma G.P., Silver K.H., McLaughlin M., Mauser J., Gaasch W.H. Impact of chamber geometry and gender on left ventricular systolic function in patients>60 years of age with aortic stenosis. Am J Cardiol. 74:1994;794-798.
18. Legget M.E., Kuusisto J., Healy N.L., et al. Gender differences in left ventricular function at rest and with exercise in asymptomatic aortic stenosis. Am Heart J. 131:1996;94-100.
19. Forman D., Cittadini A A.G., Douglas P.S., Wei J.Y. Cardiac morphology and function in senescent rats: gender-related differences. J Am Coll Cardiol. 30:1997;1872-1877.
20. Douglas P., Katz S., Weinberg E.O., et al. Hypertrophic remodeling: gender differences in the early response to left ventricular pressure overload. J Am Coll Cardiol. 32:1998;1118-1125.
21. Anversa P., Li P., Sonnenblick E.H., Olivetti G. Effects of aging on the quantitative structural properties of the coronary vasculature and microvasculature in Fischer 344 rats. Am J Physiol. 267:1994;H1062-H1073.
22. Olivetti G., Abbi R., Quaini F., et al. Apoptosis in the failing human heart. N Engl J Med. 336:1997;1131-1141.
23. Kajstura J., Cheng W., Sarangarajan R., et al. Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats. Am J Physiol. 271:1996;H1215-H1228.
24. Benjamin I.J., Jalil J.E., Tan L.B., et al. Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. Circ Res. 67:1989;657-670.
25. Capasso J.M., Palackal T., Olivetti G., Anversa P. Severe myocardial dysfunction induced by ventricular remodeling in aging rat hearts. Am J Physiol. 259:1990;H1086-H1096.
26. Anversa P., Olivetti G., Loud A.V. Morphometric studies of left ventricular hypertrophy. Tarazi R.C., Dunbar J.B. Perspectives in cardiovascular research. Cardiac hypertrophy in hypertension. 8:1983;27-39 Raven Press, New York.
27. Anversa P., Melissari M., Beghi C., Olivetti G. Structural compensatory mechanisms in the rat heart in early spontaneous hypertension. Am J Physiol. 246:1984;H739-H746.
28. Teiger E., Dam T.V., Richard L., et al. Apoptosis in pressure overload induced heart hypertrophy in the rat. J Clin Invest. 97:1996;2891-2897.
29. Olivetti G., Ricci R., Lagrasta C., et al. Cellular basis of wall remodeling in long term pressure overload induced right ventricular hypertrophy in rats. Circ Res. 63:1988;648-657.
30. Olivetti G., Ricci R., Anversa P. Hyperplasia of myocyte nuclei in long-term cardiac hypertrophy in rats. J Clin Invest. 80:1987;1818-1822.
31. Olivetti G., Lagrasta C., Ricci R., et al. Long-term pressure-induced cardiac hypertrophy: capillary and mast cell proliferation. Am J Physiol. 257:1989;H1766-H1772.
32. Capasso J.M., Palackal T., Olivetti G., Anversa P. Left ventricular failure induced by long-term hypertension in rats. Circ Res. 66:1990;1400-1412.
33. Anversa P., Palackal T., Sonnenblick E.H., Olivetti G., Capasso J.M. Hypertensive cardiomyopathy: Myocyte nuclei hyperplasia in the mammalian heart. J Clin Invest. 85:1990;994-997.
34. Pahor M., Bernabei R., Sgadari A., et al. Enalapril prevents cardiac fibrosis and arrhythmias in hypertensive rats. Hypertension. 18:1991;148-157.
35. Boluyt M.O., Oneill L., Meredith A.L., et al. Alterations in cardiac gene expression during the transition from stable hypertrophy to heart failure-marked upregulation of genes encoding extracellular matrix components. Circ Res. 75:1994;23-32.
36. Levy D., Larson M.G., Vasan R.S., Kannel W.C., Ho K.K.L. The progression from hypertension to congestive heart failure. J Am Med Assoc. 275:1996;1557-1562.
37. Anversa P., Capasso J.M. Loss of intermediate-sized coronary arteries and capillary proliferation following left ventricular failure in rats. Am J Physiol. 260:1991;H1552-H1560.
38. Rakusan K., Flanagan M.F., Geva T., Southern J., Vanpraagh R. Morphometry of human coronary capillaries during normal growth and the effect of age in left ventricular pressure-overload hypertrophy. Circulation. 86:1992;38-46.
39. Olivetti G., Melissari M., Balbi T., et al. Myocyte cellular hypertrophy is responsible for ventricular remodelling in the hypertrophied heart of middle aged individuals in the absence of cardiac failure. Cardiovasc Res. 28:1994;1199-1208.
40. Olivetti G., Melissari M., Balbi T., et al. Myocyte nuclear and possible cellular hyperplasia contribute to ventricular remodeling in the hypertrophic senescent heart in humans. J Am Coll Cardiol. 24:1994;140-149.
41. Tazelaar H.D., Edwards W.D. Pathology of cardiac transplantation-recipient hearts (Chronic heart failure) and donor hearts (Acute and chronic rejection). Mayo Clin Proc. 67:1992;685-696.
42. Beltrami C.A., Finato N., Rocco M., et al. Structural basis of end-stage failure in ischemic cardiomyopathy in humans. Circulation. 89:1994;151-163.
43. Beltrami C.A., Finato N., Rocco M., et al. The cellular basis of dilated cardiomyopathy in humans. J Mol Cell Cardiol. 27:1995;291-305.
44. Dipla K., Mattiello J.A., Jeevanandam V., Houser S.R., Margulies K.B. Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure. Circulation. 97:1998;2316-2322.
45. Batista R.J., Verde J., Nery P., et al. Partial left ventriculectomy to treat end-stage heart disease. Ann Thorac Surg. 64:1997;634-638.
46. Olivetti G., Capasso J.M., Sonnenblick E.H., Anversa P. Side-to-side slippage of myocytes partecipates in ventricular wall remodeling acutely after myocardial infarction in rats. Circ Res. 67:1990;23-34.
47. Olivetti G., Capasso J.M., Meggs L.G., Sonnenblick E.H., Anversa P. Cellular basis of chronic ventricular remodeling after myocardial infarction in the rat. Circ Res. 68:1991;856-869.
48. Cheng W., Li B., Kajstura J., et al. Stretch-induced programmed myocyte cell death. J Clin Invest. 96:1995;2247-2259.
49. Liu Y., Cigola E., Cheng W., et al. Myocyte nuclear mitotic division and programmed myocyte cell death characterize the cardiac myopathy induced by rapid ventricular pacing in dogs. Lab Invest. 73:1995;771-787.
50. Bardales R.H., Shea Hailey L., Xie S.S., Schaefer R.F., Hsu S. In situ apoptosis assay for the detection of early acute myocardial infarction. Am J Pathol. 149:1996;821-829.
51. Misao J., Hayakawa Y., Ohno M., et al. Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction. Circulation. 94:1996;1506-1512.
52. Saraste A., Pulkki K., Kallajoki M., et al. Apoptosis in human acute myocardial infarction. Circulation. 95:1997;320-323.
53. Olivetti G., Quaini F., Sala R., et al. Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart. J Mol Cell Cardiol. 28:1996;2005-2016.
54. Li Z., Bing O.H.L., Long X., Robinson K., Lakatta E.G. Increased cardiomyocyte apoptosis during the transition to heart failure in the spontaneously hypertensive rat. Am J Physiol. 272:1997;H2313-H2319.
55. Weinberg E.O., Schoen F.J., George D., et al. Angiotensin-converting enzyme inhibition prolongs survival and modifies the transition to heart failure in rats with pressure overload hypertrophy due to ascending aortic stenosis. Circulation. 90:1994;1410-1422.
56. Lindpaintner K., Jin M.W., Niedermaier N., Wilhelm M.J., Ganten D. Cardiac angiotensinogen and its local activation in the isolated perfused beating heart. Circ Res. 67:1990;564-573.
57. Cigola E., Kajstura J., Li B., Meggs L.G., Anversa P. Angiotensin II activates programmed myocyte cell death in vitro. Exp Cell Res. 231:1997;363-371.
58. Kajstura J., Cigola E., Malhotra A., et al. Angiotensin II induces apoptosis in adult ventricular myocytes in vitro. J Mol Cell Cardiol. 29:1997;859-870.
59. Communal C., Singh K., Pimentel D.R., Colucci W.S. Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the beta-adrenergic pathway. Circulation. 98:1998;1329-1334.
60. Shizukuda Y., Buttrick P.M., Geenen D.L., et al. Beta-adrenergic stimulation causes cardiocyte apoptosis: influence of tachycardia and hypertrophy. Am J Physiol. 275:1998;H961-H968.
61. Wu C.F., Bishopric N.H., Pratt R.E. Atrial natriuretic peptideinduces apoptosis in neonatal rat cardiac myocytes. J Biol Chem. 272:1997;14860-14866.
62. Ing D.J., Zang J., Dzau V.J., Webster K.A., Bishopric N.H. Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide. Bak, and Bcl-x. Circ Res. 84:1999;21-33.
63. Sadoshima J., Xu Y.H., Slayter H.S., Izumo S. Autocrine release of Angiotensin-II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell. 75:1993;977-984.
64. Sadoshima J., Izumo S. Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Criticsl role of the AT1 receptor subtype. Circ Res. 73:1993;413-423.
65. Sadoshima J., Izumo S. The cellular and molecular response of cardiac myocytes to mechanical stress. Annu Rev Physiol. 59:1997;551-571.
66. Ross J. Jr. Growth hormone, cardiomyocyte contractile reserve, and heart failure. Circulation. 99:1999;15-17.
67. Frustaci A., Chimenti C., Setoguchi M., et al. Cell death in acromegalic cardiomyopathy. Circulation. 99:1999;1426-1434.
68. Gruver C.L., DeMayo F., Goldstein M.A., Means A.R. Targeted developmental overexpression of calmodulin induces proliferative and hypertrophic growth of cardiomyocytes in transgenic mice. Endocrinology. 133:1993;376-388.
69. 1-adrenergic receptor in transgenic mice induces cardiac hypertrophy. Proc Natl Acad Sci. 91:1994;10109-10113.
70. Hunter J.J., Tanaka N., Rockman H.A., Ross J. Jr., Chien K.R. Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice. J Biol Chem. 270:1995;3173-3178.
71. Vikstrom K.L., Factor S., Leinwand L.A. Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy. Mol Med. 2:1996;556-567.
72. Fentzke R.C., Korcarz C.E., Lang R.M., Lin H., Leiden J.M. Dilated cardiomyopathy in transgenic mice expressing a dominant-negative CREB transcription factor in the heart. J Clin Invest. 101:1998;2415-2426.
73. Franz W.M., Mueller O.J., Hartong R., Frey N., Katus H.A. Transgenic animal models: new avenues in cardiovascular physiology. J Mol Med. 75:1997;115-129.
74. Arber S H.J., Ross J. Jr., Hongo M., et al. MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure. Cell. 88:1997;393-403.
75. Mende U., Kagen A., Cohen A., et al. Transient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways. Proc Natl Acad Sci. 95:1998;13893-13898.
76. Kubota T., McTiernan C.F., Frye C.S., et al. Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-alpha. Circ Res. 81:1997;627-635.
77. Megeney L.A., Kablar B., Perry R.L., et al. Severe cardiomyopathy in mice lacking dystrophin and MyoD. Proc Natl Acad Sci. 96:1999;220-225.
78. Oliver P.M., Fox J.E., Kim R., et al. Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A. Proc Natl Acad Sci. 94:1997;14730-14735.
79. Astorri E., Chizzola A., Visioli O., et al. Right ventricular hypertrophy: A cytometric study on 55 human hearts. J Mol Cell Cardiol. 2:1971;99-110.
80. Astorri E., Bolognesi R., Colla B., Chizzola A., Visioli O. Left ventricular hypertrophy: a cytometric study on 42 human hearts. J Mol Cell Cardiol. 9:1977;763-775.
81. Grajek S., Lesiak M., Pyda M., et al. Hypertrophy or hyperplasia in cardiac muscle. Post-mortem human morphometric study. Eur Heart J. 14:1983;40-47.
82. Quaini F., Cigola E., Lagrasta C., et al. End-stage cardiac failure in humans is coupled with the induction of proliferating cell nuclear antigen and nuclear mitotic division in ventricular myocytes. Circ Res. 75:1994;1050-1063.
83. Reiss K., Kajstura J., Zhang X., et al. Acute myocardial infarction leads to upregulation of the IGF-1 autocrine system. DNA replication and nuclear mitotic division in the remaining viable cardiac myocytes. Exp Cell Res. 213:1994;463-472.
84. Olivetti G., Cigola E., Maestri R., et al. Aging, cardiac hypertrophy and ischemic cardiomyopathy do not affect the proportion of mononucleated and multinucleated myocytes in the human heart. J Mol Cell Cardiol. 28:1996;1463-1477.
85. Claycomb W.C., Bradshaw H.D. Acquisition of multiple nuclei and the activity of DNA polymerase alpha and reinitiation of DNA replication in terminally differentiated adult cardiac muscle cells in culture. Dev Biol. 99:1983;331-337.
86. Rumyantsev P.P., Kassem A.M. Cumulative indices of DNA synthesizing myocytes in different compartments of the working myocardium and conductive system of the rat heart muscle following extensive left ventricular infarction. Virchows Arch (B). 20:1976;329-342.
87. Oberpriller J.O., Ferrans V.J., Carroll R.J. Changes in DNA content, number of nuclei and cellular dimensions of young rat atrial myocytes in response to left coronary artery ligation. J Mol Cell Cardiol. 15:1983;31-42.
88. Kardami E. Stimulation and inhibition of cardiac myocyte proliferation in vitro. Molec Cell Biochem. 92:1990;129-135.
89. Nag A.C., Carey T.R., Cheng M. DNA synthesis in rat heart cells after injury and regeneration of myocardia. Tissue Cell. 15:1983;597-613.
90. Li R.K., Shaikh N., Weisel R.D., Williams W.G., Mickle D.A. Oxyradical-induced antioxidant and lipid changes in cultured human cardiomyocytes. Am J Physiol. 266:1994;H2204-H2211.
91. Li R.K., Mickle D.A., Weisel R.D., et al. Human pediatric and adult ventricular cardiomyocytes in culture: assessment of phenotypic changes with passaging. Cardiovasc Res. 32:1996;362-373.
92. Reiss K., Cheng W., Ferber A., et al. Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice. Proc Natl Acad Sci. 93:1996;8630-8635.
93. Soonpaa M.H., Koh G.Y., Pajak L., et al. Cyclin D1 overexpression promotes cardiomyocyte DNA synthesis and multinucleation in transgenic mice. J Clin Invest. 99:1997;2644-2654.
94. Reiss K., Cheng W., Pierzchalski P., et al. Insulin-like growth factor-1 receptor and its ligand regulate the reentry of adult ventricular myocytes into the cell cycle. Exp Cell Res. 235:1997;198-209.
95. Li J.M., Poolman R.A., Brooks G. Role of G1 phase cyclins and cyclin-dependent kinases during cardiomyocyte hypertrophic growth in rats. Am J Physiol. 275:1998;H814-H822.
96. Li RK, Mmickle DA, Weisel RD. et al. Natural history of fetal rat cardiomyocytes transplanted into adult rat myocardial scar tissue. Circulation 1997;96 (Suppl):II-179-186; discussion 186-187.
97. Leor J P.M., Quinones M.J., Kedes L.H., Kloner R.A. Transplantation of fetal myocardial tissue into the infarcted myocardium of rat. A potential method for repair of infarcted myocardium? Circulation. 94:1996;332-336.
98. Makino S., Fukuda K., Miyoshi S., et al. Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest. 103:1999;697-705.
99. Losordo D.W., Vale P.R., Symes J.F., et al. Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. Circulation. 98:1998;2800-2804.
100. Akhter S.A., Luttrell L.M., Rockman H.A., et al. Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science. 280:1998;574-577.