Angiotensin II induces apoptosis of adult ventricular myocytes in vitro

Journal of Molecular and Cellular Cardiology

Volumn 29, Issue 3, 1997, Pages 859-870

  Kajstura, Jan ^a   Cigola, Elena ^a   Malhotra, Ashwani ^b   Li, Peng ^a   Cheng, Wei ^a   Meggs, Leonard G ^a   Anversa, Piero ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Ang II; Apoptosis; AT1 receptor subtype; Intracellular Ca2+; PKC

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN; CALCIUM ION; CHELERYTHRINE; DNA FRAGMENT; DNA NUCLEOTIDYLEXOTRANSFERASE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; LOSARTAN; PROTEIN KINASE C;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; DNA STRAND BREAKAGE; HEART MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0031105576     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1996.0333     Document Type: Article

References (52)

1. ABDELLATIF MM, NEUBAUER CF, LEDERER WJ, ROGERS TB, 1991. Angiotensin-induced desensitization of the phosphoinositide pathway in cardiac cells occurs at the level of the receptor. Circ Res 69: 800-809.
2. ANVERSA P, KAJSTURA J, OLIVETTI G, 1996. Myocyte cell death in heart failure. Curr Opin Cardiol 11: 245-251.
3. BAKER KM, ACETO JF, 1990. Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells. Am J Physiol 259: H610-H618.
4. BAKER KM, SINGER HA, ACETO JF, 1989. Angiotensin II receptor-mediated stimulation of cytosolic-free calcium and inositol phosphates in chick myocytes. J Pharmacol Exp Ther 251: 578-585.
5. BOURINET E, FOURNIER F, LORY P, CHARNET P, NARGEOT J, 1992. Protein kinase C regulation of cardiac calcium channels expressed in Xenopus oocytes. Pfluger's Arch 421: 247-255.
6. CAPASSO JM, LI P, ANVERSA P, 1993. Cytosolic calcium transients in myocytes isolated from rats with ischemic heart failure. Am J Physiol 265: H1953-H1964.
7. CHENG W, LI B, KAJSTURA J, LI P, WOLIN MS, SONNENBLICK EH, HINTZE TH, OLIVETTI G, ANVERSA P, 1995. Stretch-induced programmed myocyte cell death. J Clin Invest 96: 2247-2259.
8. CLERK A, BOGOYEVITCH MA, FULLER SJ, LAZOU A, PARKER PJ, SUGDEN PH, 1995. Expression of protein kinase C isoforms during cardiac ventricular development. Am J Physiol 269: H1087-H1097.
9. DISATNIK M-H, BURAGGI B, MOCHLY-ROSEN D, 1994. Localization of protein kinase C isozymes in cardiac myocytes. Exp Cell Res 210: 287-297.
10. DISATNIK M-H, NASHONE-JONES S, MOCHLY-ROSEN D, 1995. Stimulus-dependent subcellular localization of activated protein kinase C; a study with acidic fibroblast growth factor and transforming growth factor-β1 in cardiac myocytes. J Mol Cell Cardiol 27: 2473-2481.
11. DOSEMECI RS, DHALLAN RS, COHEN NM, LEDERER WJ, ROGERS TB, 1988. Phorbol ester increases calcium current and simulates the effects of angiotensin II on cultured neonatal rat heart myocytes. Circ Res 62: 347-357.
12. DOSTAL DE, ROTHBLUM KN, CHERNIN MI, COOPER GR, BAKER KM, 1992. Intracardiac detection of angiotensinogen and renin: a localized renin-angiotensin system in neonatal rat heart. Am J Physiol 263: C838-C850.
13. GERSCHENSON LE, ROTELLO RJ, 1992. Apoptosis: A different type of cell death. FASEB J 6: 2450-2455.
14. GIBBONS WR, 1986. Cellular control of cardiac contraction. In: Fozzard HA, Haber E, Jennings RB, Katz AM, Morgan EH (eds). The Heart and Cardiovascular System. New York:, Raven Press, 747-778.
15. GONG J, TRAGANOS F, DARZYNKIEWICZ Z, 1994. A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. Anal Biochem 218: 314-319.
16. GOTTLIEB RA, BURLESON KO, KLONER RA, BABLOR BM, ENGLER RL, 1994. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest 94: 1621-1628.
17. 2+ indicators with greatly improved fluorescent properties. J Biol Chem 260: 3440-3450.
18. HERBERT JM, AUGEREAU JM, GLEYE J, MAFFRAND JP, 1990. Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem Biophys Res Commun 172: 993-999.
19. ICHIKI T, LABOSKY PA, SHLOTA C, OKUYAMA S, IMAGAWA Y, FOGO A, NIIMURA AF, ICHIKAWA I, HOGAN BLM, INAGAMI T, 1995. Effects of blood pressure and exploratory behavior of mice lacking angiotensin II type-2 receptor. Nature 377: 748-750.
20. KAJSTURA J, CHENG W, SARANGARAJAN R, LI P, LI B, NITAHARA JA, CHAPNICK S, REISS K, OLIVETTI G, ANVERSA P, 1996a. Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats. Am J Physiol 271: H1215-H1228.
21. KAJSTURA J, CHENG W, REISS K, CLARK WA, SONNENBLICK EH, KRAJEWSKI S, REED JC, OLIVETTI G, ANVERSA P, 1996b. Apoptotic and necrotic myocyte cell death are independent contributing variables of infarct size in rats. Lab Invest 74: 86-107.
22. KAJSTURA J, MANSUKHANI M, CHENG W, REISS K, KRAJEWSKI S, REED JC, QUAINI F, SONNENBLICK EH, ANVERSA P, 1995. Programmed cell death and expression of the protooncogene bcl-2 in myocytes during postnatal maturation of the heart. Exp Cell Res 219: 110-121.
23. KAJSTURA J, ZHANG X, REISS K, SZOKE E, LI P, LAGRASTA C, CHENG W, DARZYNKIEWICZ Z, OLIVETTI G, ANVERSA P, 1994. Myocyte cellular hyperplasia and myocyte cellular hypertrophy contribute to chronic ventricular remodeling in coronary artery narrowing-induced cardiomyopathy in rats. Circ Res 74: 383-400.
24. KEM DC, JOHNSON EIM, CAPPONI AM, CHARDONNENS D, LANG U, BLONDEL B, KOSHIDA H, VALLOTTON MD, 1991. Effects of angiotensin II on cytosolic free calcium in neonatal rat cardiomyocytes. Am J Physiol 261: C77-C85.
25. LACKS SA, 1981. Deoxyribonuclease I in mammalian tissue. Specificity of inhibition by actin. J Biol Chem 256: 2644-2648.
26. LAM M, DUBYAK G, DISTELHORST CW, 1993. Effect of glucocorticosteroid treatment on intracellular calcium homeostasis in mouse lymphoma cells. Molec Endocrinol 7: 686-693.
27. 2+ content in single myocytes of guinea pig heart: effect of ryanodine. Am J Physiol 259: H1222-H1229.
28. LI P, SONNENBLICK EH, ANVERSA P, CAPASSO JM, 1994. Length-dependent modulation of ANG II inotropism in rat myocardium: effects of myocardial infarction. Am J Physiol 266: H779-H786.
29. LIU Y, CIGOLA E, CHENG W, KAJSTURA J, OLIVETTI G, HINTZE TH, ANVERSA P, 1995. Myocyte nuclear mitotic division and programmed myocyte cell death characterize the cardiac myopathy induced by rapid ventricular pacing in dogs. Lab Invest 73: 771-787.
30. 2-receptor subtypes in hypertrophied rat hearts. Am J Physiol 267: H844-H852.
31. MEGGS LG, COUPET J, HUANG H, CHENG W, LI P, CAPASSO JM, HOMCY CJ, ANVERSA P, 1993. Regulation of angiotensin II receptors on ventricular myocytes after myocardial infarction in rats. Circ Res 72: 1149-1162.
32. NISHIZUKA Y, 1986. Studies and perspectives of protein kinase C. Science 233: 305-312.
33. PEITSCH MC, POLZAS B, STEPHAN H, CROMPTON T, MCDONALD HR, MANNHERZ HG, TSCHOPP J, 1993. Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). EMBO J 12: 371-377.
34. 2+ antagonists inhibit DNA fragmentation and toxic cell death induced by acetaminophen. FASEB J 7: 453-463.
35. REISS K, CAPASSO JM, HUANG H, MEGGS LG, LI P, ANVERSA P, 1993. ANG II receptors, c-myc, and c-jun in myocytes after myocardial infarction and ventricular failure. Am J Physiol 264: H760-H769.
36. RYBIN VO, STEINBERG SF, 1994. Protein kinase C isoform expression and regulation in the developing rat heart. Circ Res 74: 299-309.
37. 1 receptor subtype. Circ Res 73: 413-423.
38. SADOSHIMA J, XU J, SLAYTER HS, ISUMO S, 1993. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 75: 977-984.
39. SCHUNKERT H, DZAU VJ, TANG SS, HIRSCH AT, APSTEIN C, LORELL BH, 1990. Increased rat cardiac angiotensin converting enzyme activity and mRNA levels in pressure overload left ventricular hypertrophy: effects on coronary resistance, contractility and relaxation. J Clin Invest 86: 1913-1920.
40. SECHI LA, GRIFFIN CA, GRADY EF, KALINYAK JE, SCHAMBELAN M, 1992. Characterization of angiotensin II receptor subtypes in rat heart. Circ Res 71: 1482-1489.
41. 2+ channels in Xenopus oocytes by protein kinase C. FEBS Lett 306: 113-118.
42. SVEDBERG K, HELD P, KJEKSHUS J, RASMUSSEN K, RYDEN L, WEDEL H, 1992. Effects of the early administration of enalapril on mortality in patients with acute myocardial infarction: results of the Cooperative New Scandinavian Enalapril Survival Study II (CONSENSUS II). N Engl J Med 327: 678-684.
43. TAN LB, JALIL JE, PICK R, JANICKI JS, WEBER KT, 1991. Cardiac myocyte necrosis induced by angiotensin II. Circ Res 69: 1185-1195.
44. The CONSENSUS Trial Study Group, 1987. Effects of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Study Group. N Engl J Med 316: 1429-1435.
45. The SOLVD Investigators. 1992. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. N Engl J Med 327: 685-691.
46. TIMMERMANS PBMWM, WONG PC, CHIU AT, HERBLIN WF, 1991. Nonpeptide angiotensin II receptor antagonists. Trends Pharmacol Sci 12: 55-62.
47. TIMMERMANS PBMWM, WONG PC, CHIU AT, HERBLIN WF, BENFIELD P, CARINI DJ, LEE RJ, WEXLER RR, SAYRE JM, SMITH RD, 1993. Angiotensin II receptors and angiotensin II antagonists. Pharmacol Rev 45: 205-251.
48. WALLENSTEIN S, ZUCKER CL, FLEISS JL, 1980. Some statistical methods useful in circulation research. Circ Res 47: 1-9.
49. WEINBERG EO, SCHOEN FJ, GEORGE D, KAGAYA Y, DOUGLAS PS, LITWIN SE, SCHUNKERT H, BENEDICT CR, LORELL BH, 1994. Angiotensin-converting enzyme inhibition prolongs survival and modifies the transition to heart failure in rats with pressure overload hypertrophy due to ascending aortic stenosis. Circulation 90: 1410-1422.
50. WYLLIE AH, ARENDS MJ, MORRIS RG, WALKER SW, EVAN G, 1992. The apoptosis endonuclease and its regulation. Semin Immunol 4: 381-387.
51. ZHAN Q, FAN S, BAI I, GUILLOUE C, LIEBERMANN DA, O'CONNOR PM, FORNACE AJ, 1994. Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis. Oncogene 9: 3743-7351.
52. ZHANG X, DOSTAL DE, REISS K, CHENG W, KAJSTURA J, LI P, HUANG H, SONNENBLICK EH, MEGGS LG, BAKER KM, ANVERSA P, 1995. Identification and activation of autocrine renin-angiotensin system in adult ventricular myocytes. Am J Physiol 269: H1791-H1802.