Hoxb-5 expression in the developing mouse lung suggests a role in branching morphogenesis and epithelial cell fate

Histochemistry and Cell Biology

Volumn 108, Issue 6, 1997, Pages 495-504

  Volpe, MaryAnn V ^a   Martin, Ana ^a   Vosatka, Robert J ^a   Mazzoni, Cynthia L ^a   Nielsen, Heber C ^a  

^a TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; HOMEODOMAIN PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; HOMEOBOX; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; LUNG DEVELOPMENT; MALE; MORPHOGENESIS; MOUSE; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL;

ANIMALS; BLOTTING, WESTERN; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; HOMEODOMAIN PROTEINS; IMMUNOHISTOCHEMISTRY; LUNG; MICE; PREGNANCY;

ANIMALIA; MAMMALIA; RODENTIA;

EID: 0031468415     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004180050190     Document Type: Article

References (64)

1. Adamson IYR, King GM (1984) Sex differences in development of fetal rat lung, II. Quantitative morphology of epithelial-mesenchymal interactions. Lab Invest 50:461-468
2. Beachy PA (1990) A molecular view of the Ultrabithorax homeotic gene of Dmsophila. Trends Genet 6:46-51
3. Bellusci S, Henderson R, Winnier G, Oikawa T, Hogan BLM (1996) Evidence from normal expression and targeted misexpression that bone morphogenetic protein-4 (BMP-4) plays a role in mouse embryonic lung morphogenesis. Development 122:1693-1702
4. Benson GV, Nguyen THE, Maas RL (1995) The expression pattern of the murine Hoxa-10 gene and the sequence recognition of its homeodomain reveal specific properties of abdominal b-like genes. Mol Cell Biol 15:1591-1601
5. Bogue CW, Gross I, Vasavada H, Dynia DW, Wilson CM, Jacobs HC (1994) Identification of hox genes in newborn lung and effects of gestational age and retinoic acid on their expression. Am J Physiol 266:L448-L454
6. Bogue CW, Lou LJ, Vasavada H, Wilson CM, Jacobs HC (1996) Expression of Hoxb genes in the developing mouse foregut and lung. Am J Respir Cell Mol Biol 15:163-171
7. Carrasco AE, Malacinski GM (1987) Localization of Xenopus homeo-box gene transcripts during embryogenesis and in the adult nervous system. Dev Biol 121:69-81
8. Carroll SB, Laymon RA, Mc Cutcheon MA, Riley PD, Scott MP (1986) The localization and regulation of Antennapedia protein expression in Drosophila embryos. Cell 47:113-122
9. Coletta PL, Shimeld SM, Chauldhure C, Müller U, Clarke JP, Sharpe PT (1991) Characterization of the murine Hox-3.3 gene and its promoter. Mech Dev 35:129-142
10. Desplan C, Theis J, O'Farrell PH (1985) The Dmsophila developmental gene engrailed encodes a sequence-specific DNA binding activity. Nature 318:630-635
11. Dony C, Gruss P (1987) Specific expression of the hox 1.3 homeo box gene in murine embryonic structures originating from or induced by the mesoderm. EMBO J 6:2965-2975
12. Dressier GR, Gruss P (1988) Do multigene families regulate vertebrate development? Trends Genet 4:214-219
13. De Robertis EM, Oliver G, Wright CVE (1990) Homeoboxgenes and the vertebrate bodyplan. Sci Am 263:46-52
14. Edelman GM (1992) Morphoregulation. Dev Dyn 193:2-10
15. Fainsod A, Awgulewitsch A, Ruddle FH (1987) Expression of the murine homeo box gene hox 1.5 during embryogenesis. Dev Biol 124:125-133
16. Feinberg AA, Utset MF, Bogarad LD, Hart CP, Awgulewitsch A, Ferguson-Smith A, Fainsod A, Rabin M, Ruddle FH (1987) Homeo box genes in murine development. Curr Top Mol Biol 23:232-256
17. Frohman MA, Boyle M, Martin GR (1990) Isolation of the mouse hox-2.9 gene: analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm. Development 110:589-607
18. Gaunt SJ (1988) Mouse homeobox gene transcripts occupy different but overlapping domains in embryonic germ layers and organs: a comparison of hox-3.1 and hox-1.5. Development 103:135-144
19. Gaunt SJ (1991) Expression patterns of mouse hox genes: clues to an understanding of developmental and evolutionary strategies. Bioessays 13:505-513
20. Gaunt SJ, Krumlauf R, Duboule D (1989) Mouse homeo-genes within a subfamily, hox-1.4, -2.6 and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation. Development 107:131-141
21. Gaunt SJ, Coletta PL, Pravtcheva D, Sharpe PT (1990) Mouse hox-3.4: homeobox sequence and embryonic expression patterns compared with other members of the hox gene network. Development 109:329-339
22. Gehring WJ, Affolter M, Bürglin T (1994) Homeodomain proteins. Annu Rev Biochem 63:487-526
23. Giampaolo A, Acampora D, Zappavigna V, Pannese M. D'Esposito M, Care' A, Faiella A, Stornaiuolo A, Russo G, Simeone A, Boncinelli E, Peschle C (1989) Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system. Differentiation 40:191-197
24. Graham A, Papalopulu N, Krumlauf R (1989) The murine and Drosophila homeobox gene complexes have common features of organization and expression. Cell 57:367-378
25. Graham A, Maden M, Krumlauf R (1991) The murine hox-2 genes display dynamic dorsoventral patterns of expression during central nervous system development. Development 112:255-264
26. Gutman A, Gilthorpe J, Rigby PWJ (1994) Multiple positive and negative regulatory elements in the promoter of the mouse homeobox gene Hoxb-4. Mol Cell Biol 14:8143-8154
27. Hafen E, Levine M, Gehring WJ (1984) Regulation of antennapedia transcript distribution by the bithorax complex in Drosophila. Nature 307:287-289
28. Harding K, Wedeen C, McGinnis W, Levine M (1985) Spatially regulated expression of homeotic genes in Drosophila. Science 229:1236-1242
29. Hogan BLM, Holland PWH, Lumsden A (1988) Expression of the homeobox gene, hox 2.1, during mouse embryogenesis. In: Eguchi G, Okada TS, Saxén L (eds) Regulatory mechanisms in developmental processes. Elsevier Scientific Publishers Ireland, Ltd. Dublin, Ireland, pp 39-44
30. Holland PWH, Hogan BLM (1988a) Spatially restricted patterns of expression of the homeobox-containing gene hox 2.1 during mouse embryogenesis. Development 102:159-174
31. Holland PWH, Hogan BLM (1988b) Expression of homeo box genes during mouse development: a review. Genes Dev 2:773-782
32. Jackson IJ, Schofield P, Hogan B (1985) A mouse homoeo box gene is expressed during embryogenesis and in adult kidney. Nature 317:745-748
33. Jones FS, Prediger EA, Bittner DA, DeRobertis EM, Edelman GM (1992) Cell adhesion molecules as targets for hox genes: neural cell adhesion molecule promoter activity is modulated by cotransfection with hox-2.5 and -2.4. Proc Natl Acad Sci USA 89:2086-2090
34. Kessel M, Schulze F, Fibi M, Gruss P (1987) Primary structure and nuclear localization of a murine homeodomain protein. Proc Natl Acad Sci USA 84:5306-5310
35. Krumlauf R (1994) Hox genes in vertebrate development. Cell 78:191-201
36. Krumlauf R, Holland PWH, McVey JH, Hogan BLM (1987) Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1. Development 99:603-617
37. Laemmli UK (1970) Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227:680-685
38. Levine M, Rubin GM, Tijan R (1984) Human DNA sequences homologous to a protein coding region conserved between homeotic genes of Drosophila. Cell 38:667-673
39. Lewis EB (1978) A gene complex controlling segmentation in Drosophila. Nature 276:565-570
40. Lowney P, Corral J, Detmer K, Le Beau MM, Deaven L, Lawrence HJ, Largman C (1991) A human Hox 1 homeobox gene exhibits myeloid-specific expression of alternative transcripts in human hematopoietic cells. Nucleic Acids Res 19:3443-3449
41. Lowry OH, Rosebrough NJ, Fair AL, Randall RJ (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193: 265-275
42. McGinnis W, Hart CP, Gehring WJ, Ruddle FH (1984) Molecular cloning and chromosome mapping of a mouse DNA sequence homologous to homeotic genes of Drosophila. Cell 38: 675-680
43. McGinnis W, Levine MS, Hafen E, Kuroiwa A, Gehring WJ (1993) A conserved DNA sequence in homeotic genes of Drosophila antennapedia and bithorax complexes. J Natl Inst Health Res 5:68-76
44. Nielsen HC, Martin A, Volpe MA, Hatzis D, Vosatka RJ (1997) Growth factor control of growth and epithelial differentiation in embryonic lungs. Biochem Mol Med 60:38-48
45. Oliver G, Wright CVE, Hardwicke K, DeRobertis EM (1988) Differential antero-posterior expression of two proteins encoded by a homeobox gene in Xenopus and mouse embryos. EMBO J 7:3199-3209
46. Peters K, Werner S, Liao X, Wert S, Whitsett J, Williams L (1994) Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung. EMBO J 13:3296-3301
47. Rancourt DE, Tsuzuki T, Capecchi MR (1995) Genetic interaction between hoxb-5 and hoxb-6 is revealed by non-allelic, non-complementation. Genes Dev 9:108-122
48. Ruddle FH, Bartels JL, Bentley KL, Kappen C, Murtha MT, Pendelton JW (1994) Evolution of Hox genes. Annu Rev Genet 28:423-442
49. Schughart K, Kappen C, Ruddle FH (1988) Mammalian homeobox containing genes: genome organization, structure, expression and evolution. Br J Cancer Suppl 58:9-13
50. Scott MP (1992) Vertebrate homeobox gene nomenclature. Cell 71:551-553
51. Serfling E (1989) Autoregulation - a common property of eukaryotic transcription factors? Trends Genet 5:131-133
52. Serra R, Pelton RW, Moses HL (1994) TGFβl inhibits branching morphogenesis and N-myc expression in lung bud cultures. Development 120:2153-2161
53. Shepherd JCW, McGinnis W, Carrasco AE, DeRobertis EM, Gehring WJ (1984) Fly and frog homoeo domains show homologies with yeast mating type regulatory proteins. Nature 310:70-71
54. Shiratori M, Oshika E, Ung LP, Singh G, Shinozuka H, Warburton D, Michalopoulos G, Katyal SI (1996) Keratinocyte growth factor and embryonic rat lung morphogenesis. Am J Respir Cell Mol Biol 15:328-338
55. Simeone A, Mavilio F, Acampora D, Giampaolo A, Faiella A, Zappavigna V, D'Esposito M, Pannese M, Russo G, Boncinelli E, Peschle C (1987) Two human homeobox genes, cl and c8: structure analysis and expression in embryonic development. Proc Natl Acad Sci USA 84:4914-4918
56. Souza P, Tanswell AK, Post M (1996) Different roles for PDGF-α and -β receptors in embryonic lung development. Am J Respir Cell Mol Biol 15:551-562
57. Treisman J, Harris E, Wilson D, Desplan C (1992) The homeodomain: a new face for the helix-turn-helix. Bioessays 14:145-149
58. Volpe MA, Sibilia M, Wagner EF, Nielsen HC (1996) Embryonic lung branching morphogenesis, cell proliferation, and differentiation are altered in epidermal growth factor receptor (EGF-R)-/-transgenic 129/SV × C57BL/6 mice. Pediatr Res 39:70A
59. Wakimoto BT, Kaufman TC (1981) Analysis of larval segmentation in lethal genotypes associated with the Antennapedia gene complex in Drosophila melanogaster. Dev Biol 81:51-64
60. Wall NA, Jones CM, Hogan BLM, Wright CVE (1992) Expression and modification of hox 2.1 protein in mouse embryos. Mech Dev 37:111-120
61. Warburton DW, Seth R, Shum L, Horcher PG, Hall FL, Werb Z, Slavkin HC (1992) Epigenetic role of epidermal growth factor expression and signalling in embryonic mouse lung morphogenesis. Dev Biol 149:123-133
62. Wilkinson DG, Bhatt S, Cook M, Boncinelli E, Krumlauf R (1989) Segmental expression of Hox 2 homeobox-containing genes in the developing mouse hindbrain. Nature 341:405-409
63. Zappavigna V, Renucci A, Izpisu'a-Belmonte J, Urier G, Peschle C, Duboule D (1991) Hox 4 genes encode transcription factors with potential auto- and cross-regulatory capacities. EMBO J 10:4177-4187
64. Zhao JJ, Lazzarini RA, Pick L (1993) The mouse Hox 1.3 gene is functionally equivalent to the Drosophila Sex combs reduced gene. Genes Dev 7:343-354