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Volumn 74, Issue 2, 2000, Pages 490-500

Complex regulation of tau exon 10, whose missplicing causes frontotemporal dementia

Author keywords

Expression pattern of regulated isoforms; Frontotemporal dementia; Microtubule binding domain; Microtubule associated protein tau; Regulation of alternative splicing

Indexed keywords

DNA; RNA; TAU PROTEIN;

EID: 0033978622     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.740490.x     Document Type: Article
Times cited : (82)

References (88)
  • 1
    • 0029025083 scopus 로고
    • Presence of exon splicing silencers within human immunodeficiency virus type 1 tat exon 2 and tat-rev exon 3: Evidence for inhibition mediated by cellular factors
    • Amendt B. A., Si Z. H., and Stoltzfus C. M. (1995) Presence of exon splicing silencers within human immunodeficiency virus type 1 tat exon 2 and tat-rev exon 3: evidence for inhibition mediated by cellular factors. Mol. Cell. Biol 15, 4606-4615.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 4606-4615
    • Amendt, B.A.1    Si, Z.H.2    Stoltzfus, C.M.3
  • 2
    • 0026488111 scopus 로고
    • Structure and novel exons of the human tau gene
    • Andreadis A., Brown W. M., and Kosik K. (1992) Structure and novel exons of the human tau gene. Biochemistry 31, 10626-10633.
    • (1992) Biochemistry , vol.31 , pp. 10626-10633
    • Andreadis, A.1    Brown, W.M.2    Kosik, K.3
  • 3
    • 0027300702 scopus 로고
    • The exon trapping assay partly discriminates against alternatively spliced exons
    • Andreadis A., Nisson P., Kosik K. S., and Watkins P. (1993) The exon trapping assay partly discriminates against alternatively spliced exons. Nucleic Acids Res. 21, 2217-2221.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 2217-2221
    • Andreadis, A.1    Nisson, P.2    Kosik, K.S.3    Watkins, P.4
  • 4
    • 0029078383 scopus 로고
    • Relative exon affinities and suboptimal splice site signals lead to non-equivalence of two cassette exons
    • Andreadis A., Broderick J. A., and Kosik K. S. (1995) Relative exon affinities and suboptimal splice site signals lead to non-equivalence of two cassette exons. Nucleic Acids Res. 23, 3585-3593.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 3585-3593
    • Andreadis, A.1    Broderick, J.A.2    Kosik, K.S.3
  • 6
    • 0028895417 scopus 로고
    • Exon recognition in vertebrate splicing
    • Berget S. M. (1995) Exon recognition in vertebrate splicing. J. Biol. Chem. 270, 2411-2414.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2411-2414
    • Berget, S.M.1
  • 8
    • 0022365608 scopus 로고
    • The distribution of tau in the mammalian central nervous system
    • Binder L. I., Frankfurter A., and Rebhun L. I. (1986) The distribution of tau in the mammalian central nervous system. J. Cell Biol. 101, 1371-1378.
    • (1986) J. Cell Biol. , vol.101 , pp. 1371-1378
    • Binder, L.I.1    Frankfurter, A.2    Rebhun, L.I.3
  • 9
    • 0029382603 scopus 로고
    • Finding splice sites within a wilderness of RNA
    • Black D. L. (1995) Finding splice sites within a wilderness of RNA. RNA 1, 763-771.
    • (1995) RNA , vol.1 , pp. 763-771
    • Black, D.L.1
  • 10
    • 0029922250 scopus 로고    scopus 로고
    • Tau is enriched on dynamic microtubules in the distal region of growing axons
    • Black M. M., Slaughter T., Moshiah S., Obrocka M., and Fischer I. (1996) Tau is enriched on dynamic microtubules in the distal region of growing axons. J. Neurosci. 16, 3601-3619.
    • (1996) J. Neurosci. , vol.16 , pp. 3601-3619
    • Black, M.M.1    Slaughter, T.2    Moshiah, S.3    Obrocka, M.4    Fischer, I.5
  • 11
    • 0028785525 scopus 로고
    • Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain
    • Brandt R., Léger J., and Lee G. (1995) Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain. J. Cell Biol. 131, 1327-1340.
    • (1995) J. Cell Biol. , vol.131 , pp. 1327-1340
    • Brandt, R.1    Léger, J.2    Lee, G.3
  • 12
    • 0030992812 scopus 로고    scopus 로고
    • The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo
    • Buckanovich R. J. and Darnell R. B. (1997) The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo. Mol. Cell. Biol. 17, 3194-3201.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3194-3201
    • Buckanovich, R.J.1    Darnell, R.B.2
  • 13
    • 0038401969 scopus 로고    scopus 로고
    • Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity
    • Cáceres J. F., Misteli T., Screaton G. R., Spector D. L., and Krainer A. R. (1997) Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity. J. Cell Biol. 138, 225-238.
    • (1997) J. Cell Biol. , vol.138 , pp. 225-238
    • Cáceres, J.F.1    Misteli, T.2    Screaton, G.R.3    Spector, D.L.4    Krainer, A.R.5
  • 14
    • 0028232359 scopus 로고
    • A novel bipartite splicing enhancer modulates the differential processing of the human fibronectin EDA exon. 1994
    • Caputi M., Casari G., Guenzi S., Tagliabue R., Sidoli A., Mello C. A., and Baralle F. E. (1994) A novel bipartite splicing enhancer modulates the differential processing of the human fibronectin EDA exon. 1994. Nucleic Acids Res. 22, 1018-1022.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 1018-1022
    • Caputi, M.1    Casari, G.2    Guenzi, S.3    Tagliabue, R.4    Sidoli, A.5    Mello, C.A.6    Baralle, F.E.7
  • 15
    • 0030279439 scopus 로고    scopus 로고
    • Directing alternative splicing: Cast and scenarios
    • Chabot B. (1996) Directing alternative splicing: cast and scenarios. Trends Genet. 12, 472-478.
    • (1996) Trends Genet. , vol.12 , pp. 472-478
    • Chabot, B.1
  • 16
    • 0030952320 scopus 로고    scopus 로고
    • An intron element modulating 5′ splice site selection in the hnRNP A1 pre-mRNA interacts with hnRNP A1
    • Chabot B., Blanchette M., Lapierre I., and La Branche H. (1997) An intron element modulating 5′ splice site selection in the hnRNP A1 pre-mRNA interacts with hnRNP A1. Mol. Cell. Biol. 17, 1776-1786.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1776-1786
    • Chabot, B.1    Blanchette, M.2    Lapierre, I.3    La Branche, H.4
  • 17
    • 0028800302 scopus 로고
    • Conserved intron elements repress splicing of a neuron-specific src exon in vitro
    • Chan R. C. and Black D. L. (1995) Conserved intron elements repress splicing of a neuron-specific src exon in vitro. Mol. Cell. Biol. 15, 6377-6385.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6377-6385
    • Chan, R.C.1    Black, D.L.2
  • 21
    • 0030802124 scopus 로고    scopus 로고
    • Multiple interdependent sequence elements control splicing of a fibroblast growth factor receptor 2 alternative exon
    • Del Gatto F., Plet A., Gesnel M.-C., Fort C., and Breathnach R. (1997) Multiple interdependent sequence elements control splicing of a fibroblast growth factor receptor 2 alternative exon. Mol. Cell. Biol. 17, 5106-5116.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5106-5116
    • Del Gatto, F.1    Plet, A.2    Gesnel, M.-C.3    Fort, C.4    Breathnach, R.5
  • 22
    • 0032962535 scopus 로고    scopus 로고
    • hnRNP A1 recruited to an exon in vivo can function as an exon splicing silencer
    • Del Gatto-Konczak F., Olive M., Gesnel M. C., and Breathnach R. (1999) hnRNP A1 recruited to an exon in vivo can function as an exon splicing silencer. Mol. Cell. Biol. 19, 251-260.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 251-260
    • Del Gatto-Konczak, F.1    Olive, M.2    Gesnel, M.C.3    Breathnach, R.4
  • 23
    • 0028341660 scopus 로고
    • Conservation of regulated alternative splicing and identification of functional domains in vertebrate homologs to the Drosophila splicing regulator, suppressor-of-white-apricot
    • Denhez F. and Lafyatis R. (1994) Conservation of regulated alternative splicing and identification of functional domains in vertebrate homologs to the Drosophila splicing regulator, suppressor-of-white-apricot. J. Biol. Chem. 269, 16170-16179.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16170-16179
    • Denhez, F.1    Lafyatis, R.2
  • 24
    • 0021760092 scopus 로고
    • A comprehensive set of sequence analysis programs for the VAX
    • Devereux J. R., Haeberli P., and Smithies O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12, 387-395.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 387-395
    • Devereux, J.R.1    Haeberli, P.2    Smithies, O.3
  • 25
    • 0027978832 scopus 로고
    • Microfilament-associated growth cone component depends upon tau for its intracellular localization
    • DiTella M., Feiguin F., Morfini G., and Cáceres A. (1994) Microfilament-associated growth cone component depends upon tau for its intracellular localization. Cell Motil. Cytoskeleton 29, 117-130.
    • (1994) Cell Motil. Cytoskeleton , vol.29 , pp. 117-130
    • DiTella, M.1    Feiguin, F.2    Morfini, G.3    Cáceres, A.4
  • 26
    • 0023937193 scopus 로고
    • Regulation of microtubule protein levels during cellular morphogenesis in nerve growth factor-treated PC12 cells
    • Drubin D. G., Kobayashi S., Kellogg D., and Kirschner M. (1988) Regulation of microtubule protein levels during cellular morphogenesis in nerve growth factor-treated PC12 cells. J. Cell Biol. 106, 1583-1591.
    • (1988) J. Cell Biol. , vol.106 , pp. 1583-1591
    • Drubin, D.G.1    Kobayashi, S.2    Kellogg, D.3    Kirschner, M.4
  • 27
    • 0033545946 scopus 로고    scopus 로고
    • Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements
    • D'Souza I., Poorkaj P., Hong M., Nochlin D., Lee V. M., Bird T. D., and Schellenberg G. D. (1999) Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements. Proc. Natl. Acad. Sci. USA 96, 5598-5603.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5598-5603
    • D'Souza, I.1    Poorkaj, P.2    Hong, M.3    Nochlin, D.4    Lee, V.M.5    Bird, T.D.6    Schellenberg, G.D.7
  • 28
    • 0025343074 scopus 로고
    • Myosin light chain 1/3 gene alternative splicing: Cis regulation is based upon a hierarchical compatibility between splice sites
    • Gallego M. E. and Nadal-Ginard B. (1990) Myosin light chain 1/3 gene alternative splicing: cis regulation is based upon a hierarchical compatibility between splice sites. Mol. Cell. Biol. 10, 2133-2144.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 2133-2144
    • Gallego, M.E.1    Nadal-Ginard, B.2
  • 29
    • 0024745894 scopus 로고
    • Multiple isoforms of human microtubule-associated protein tau: Sequences and localization in neurofibrillary tangles of Alzheimer's disease
    • Goedert M., Spillantini M. G., Jakes R., Rutherford D., and Crowther R. A. (1989a) Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 3, 519-526.
    • (1989) Neuron , vol.3 , pp. 519-526
    • Goedert, M.1    Spillantini, M.G.2    Jakes, R.3    Rutherford, D.4    Crowther, R.A.5
  • 30
    • 0024387161 scopus 로고
    • Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: Differential expression of tau protein isoforms in human brain
    • Goedert M., Spillantini M. G., Potier M. C., Ulrich J., and Crowther R. A. (1989b) Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein isoforms in human brain. EMBO J. 8, 393-399.
    • (1989) EMBO J. , vol.8 , pp. 393-399
    • Goedert, M.1    Spillantini, M.G.2    Potier, M.C.3    Ulrich, J.4    Crowther, R.A.5
  • 31
    • 0026512915 scopus 로고
    • Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system
    • Goedert M., Spillantini M. G., and Crowther R. A. (1992) Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system. Proc. Natl. Acad. Sci. USA 89, 1983-1987.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1983-1987
    • Goedert, M.1    Spillantini, M.G.2    Crowther, R.A.3
  • 32
    • 0032214501 scopus 로고    scopus 로고
    • Tau mutations cause frontotemporal dementia
    • Goedert M., Crowther R. A., and Spillantini M. G. (1998) Tau mutations cause frontotemporal dementia. Neuron 21, 955-958.
    • (1998) Neuron , vol.21 , pp. 955-958
    • Goedert, M.1    Crowther, R.A.2    Spillantini, M.G.3
  • 33
    • 0032549748 scopus 로고    scopus 로고
    • Splicing regulation in neurons: Tinkering with cell-specific control
    • Grabowski P. J. (1998) Splicing regulation in neurons: tinkering with cell-specific control. Cell 92, 709-712.
    • (1998) Cell , vol.92 , pp. 709-712
    • Grabowski, P.J.1
  • 34
    • 0033591225 scopus 로고    scopus 로고
    • 5′ splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10
    • Grover A., Houlden H., Baker M., Adamson J., Lewis J., Prihar G., Pickering-Brown S., Duff K., and Hutton M. (1999) 5′ splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10. J. Biol. Chem. 274, 15134-15143.
    • (1999) J. Biol. Chem. , vol.274 , pp. 15134-15143
    • Grover, A.1    Houlden, H.2    Baker, M.3    Adamson, J.4    Lewis, J.5    Prihar, G.6    Pickering-Brown, S.7    Duff, K.8    Hutton, M.9
  • 35
    • 0027508470 scopus 로고
    • Cis-elements involved in alternative splicing in the rat beta-tropomyosin gene: The 3′-splice site of the skeletal muscle exon 7 is the major site of blockage in nonmuscle cells
    • Guo W. and Helfman D. M. (1993) cis-elements involved in alternative splicing in the rat beta-tropomyosin gene: the 3′-splice site of the skeletal muscle exon 7 is the major site of blockage in nonmuscle cells. Nucleic Acids Res. 21, 4762-4768.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 4762-4768
    • Guo, W.1    Helfman, D.M.2
  • 36
    • 0032561415 scopus 로고    scopus 로고
    • Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly
    • Hasegawa M., Smith M. J., Iijima M., Tabira T., and Goedert M. (1998) Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly. FEBS Lett. 437, 207-210.
    • (1998) FEBS Lett. , vol.437 , pp. 207-210
    • Hasegawa, M.1    Smith, M.J.2    Iijima, M.3    Tabira, T.4    Goedert, M.5
  • 37
    • 0033060662 scopus 로고    scopus 로고
    • FTDP-17 mutations N279K and S305N in tau produce increased splicing of exon 10
    • Hasegawa M., Smith M. J., Iijima M., Tabira T., and Goedert M. (1999) FTDP-17 mutations N279K and S305N in tau produce increased splicing of exon 10. FEBS Lett. 443, 93-96.
    • (1999) FEBS Lett. , vol.443 , pp. 93-96
    • Hasegawa, M.1    Smith, M.J.2    Iijima, M.3    Tabira, T.4    Goedert, M.5
  • 38
    • 0024498630 scopus 로고
    • Structure of the bovine tau gene: Alternatively spaced transcripts generate a gene family
    • Himmler A. (1989) Structure of the bovine tau gene: alternatively spaced transcripts generate a gene family. Mol. Cell. Biol. 9, 1389-1396.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1389-1396
    • Himmler, A.1
  • 39
    • 0024507707 scopus 로고
    • Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains
    • Himmler A., Drechsel D., Kirschner M. W., and Martin D. W. (1989) Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains. Mol. Cell. Biol. 9, 1381-1388.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1381-1388
    • Himmler, A.1    Drechsel, D.2    Kirschner, M.W.3    Martin, D.W.4
  • 40
    • 0027171212 scopus 로고
    • Elements regulating an alternatively spliced exon of the rat fibronectin gene
    • Huh G. S. and Hynes R. O. (1993) Elements regulating an alternatively spliced exon of the rat fibronectin gene. Mol. Cell. Biol. 13, 5301-5314.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5301-5314
    • Huh, G.S.1    Hynes, R.O.2
  • 41
    • 0028308631 scopus 로고
    • Regulation of alternative pre-mRNA splicing by a novel repeated hexanucleotide element
    • Huh G. S. and Hynes R. O. (1994) Regulation of alternative pre-mRNA splicing by a novel repeated hexanucleotide element. Genes Dev. 8, 1561-1574.
    • (1994) Genes Dev. , vol.8 , pp. 1561-1574
    • Huh, G.S.1    Hynes, R.O.2
  • 43
    • 0029952557 scopus 로고    scopus 로고
    • Neuron-specific alternative splicing of nonmuscle myosin II heavy chain B pre-mRNA requires a cis-acting intron sequence
    • Kawamoto S. (1996) Neuron-specific alternative splicing of nonmuscle myosin II heavy chain B pre-mRNA requires a cis-acting intron sequence. J. Biol. Chem. 271, 17613-17616.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17613-17616
    • Kawamoto, S.1
  • 44
    • 0029812945 scopus 로고    scopus 로고
    • Tau binds to the distal axon early in development of polarity in a microtubule-and microfilament-dependent manner
    • Kempf M., Clement A., Faissner A., Lee G., and Brandt R. (1996) Tau binds to the distal axon early in development of polarity in a microtubule-and microfilament-dependent manner. J. Neurosci. 16, 5583-5592.
    • (1996) J. Neurosci. , vol.16 , pp. 5583-5592
    • Kempf, M.1    Clement, A.2    Faissner, A.3    Lee, G.4    Brandt, R.5
  • 45
    • 0031922880 scopus 로고    scopus 로고
    • Frasier syndrome is caused by defective alternative splicing of WT1 leading to an altered ratio of WT1 +/-KTS splice isoforms
    • Klamt B., Koziell A., Poulat F., Wieacker P., Scambler P., Berta P., and Gessler M. (1998) Frasier syndrome is caused by defective alternative splicing of WT1 leading to an altered ratio of WT1 +/-KTS splice isoforms. Hum. Mol. Genet. 7, 709-714.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 709-714
    • Klamt, B.1    Koziell, A.2    Poulat, F.3    Wieacker, P.4    Scambler, P.5    Berta, P.6    Gessler, M.7
  • 46
    • 0024641959 scopus 로고
    • Developmentally regulated expression of specific tau sequences
    • Kosik K. S., Orecchio L. D., Bakalis S., and Neve R. L. (1989) Developmentally regulated expression of specific tau sequences. Neuron 2, 1389-1397.
    • (1989) Neuron , vol.2 , pp. 1389-1397
    • Kosik, K.S.1    Orecchio, L.D.2    Bakalis, S.3    Neve, R.L.4
  • 47
    • 0029891101 scopus 로고    scopus 로고
    • The structure and function of proteins involved in mammalian pre-mRNA splicing
    • Krämer A. (1996) The structure and function of proteins involved in mammalian pre-mRNA splicing. Annu. Rev. Biochem. 65, 367-409.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 367-409
    • Krämer, A.1
  • 48
    • 0023905288 scopus 로고
    • The primary structure of the microtubule-associated protein tau
    • Lee G., Cowan N., and Kirschner M. (1988) The primary structure of the microtubule-associated protein tau. Science 239, 285-288.
    • (1988) Science , vol.239 , pp. 285-288
    • Lee, G.1    Cowan, N.2    Kirschner, M.3
  • 49
    • 0024675418 scopus 로고
    • The microtubule binding domain of human tau protein
    • Lee G., Neve R. L., and Kosik K. S. (1989) The microtubule binding domain of human tau protein. Neuron 2, 1615-1624.
    • (1989) Neuron , vol.2 , pp. 1615-1624
    • Lee, G.1    Neve, R.L.2    Kosik, K.S.3
  • 50
    • 0033053790 scopus 로고    scopus 로고
    • SF2 and SRp55 regulation of CD45 exon 4 skipping during T cell activation
    • Lemaire R., Winne A., Sarkissian M., and Lafyatis R. (1999) SF2 and SRp55 regulation of CD45 exon 4 skipping during T cell activation. Eur. J. Immunol. 29, 823-837.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 823-837
    • Lemaire, R.1    Winne, A.2    Sarkissian, M.3    Lafyatis, R.4
  • 51
    • 0029295295 scopus 로고
    • Regulation of alternative 3′ splice site selection by constitutive splicing factors
    • Lin C. H. and Patton J. G. (1995) Regulation of alternative 3′ splice site selection by constitutive splicing factors. RNA 1, 234-245.
    • (1995) RNA , vol.1 , pp. 234-245
    • Lin, C.H.1    Patton, J.G.2
  • 52
    • 0032128255 scopus 로고    scopus 로고
    • Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins
    • Liu H. X., Zhang M., and Krainer A. R. (1998) Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins. Genes Dev. 12, 1998-2012.
    • (1998) Genes Dev. , vol.12 , pp. 1998-2012
    • Liu, H.X.1    Zhang, M.2    Krainer, A.R.3
  • 53
    • 0032435862 scopus 로고    scopus 로고
    • Alternative splicing of pre-mRNA: Developmental consequences and mechanisms of regulation
    • López A. J. (1998) Alternative splicing of pre-mRNA: developmental consequences and mechanisms of regulation. Annu. Rev. Genet. 32, 279-305.
    • (1998) Annu. Rev. Genet. , vol.32 , pp. 279-305
    • López, A.J.1
  • 54
    • 0028853922 scopus 로고
    • Functional implications for the microtubule-associated protein tau: Localization in oligodendrocytes
    • LoPresti P., Szuchet S., Papasozomenos S. C., Zinkowski R. P., and Binder L. I. (1995) Functional implications for the microtubule-associated protein tau: localization in oligodendrocytes. Proc. Natl. Acad. Sci. USA 92, 10369-10373.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10369-10373
    • LoPresti, P.1    Szuchet, S.2    Papasozomenos, S.C.3    Zinkowski, R.P.4    Binder, L.I.5
  • 55
    • 0029767662 scopus 로고    scopus 로고
    • SR proteins and splicing control
    • Manley J. L. and Tacke R. (1996) SR proteins and splicing control. Genes Dev. 10, 1569-1579.
    • (1996) Genes Dev. , vol.10 , pp. 1569-1579
    • Manley, J.L.1    Tacke, R.2
  • 56
    • 0027151934 scopus 로고
    • Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF
    • Mayeda A., Helfman D. M., and Krainer A. R. (1993) Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF. Mol. Cell. Biol. 13, 2993-3001.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2993-3001
    • Mayeda, A.1    Helfman, D.M.2    Krainer, A.R.3
  • 57
    • 0030969572 scopus 로고    scopus 로고
    • A new regulatory protein, ksrp, mediates exon inclusion through an intronic splicing enhancer
    • Min H. S., Turck C. W., Nikolic J. M., and Black D. L. (1997) A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer. Genes Dev. 11, 1023-1036.
    • (1997) Genes Dev. , vol.11 , pp. 1023-1036
    • Min, H.S.1    Turck, C.W.2    Nikolic, J.M.3    Black, D.L.4
  • 58
    • 17144453865 scopus 로고    scopus 로고
    • Human transformer-2-beta gene (SFRS10): Complete nucleotide sequence, chromosomal localization, and generation of a tissue-specific isoform
    • Nayler O., Cap C., and Stamm S. (1998) Human transformer-2-beta gene (SFRS10): complete nucleotide sequence, chromosomal localization, and generation of a tissue-specific isoform. Genomics 53, 191-202.
    • (1998) Genomics , vol.53 , pp. 191-202
    • Nayler, O.1    Cap, C.2    Stamm, S.3
  • 59
    • 0022827447 scopus 로고
    • Identification of cDNA clones for the human microtubule-associated protein, tau, and chromosomal location of the genes for tau and MAP2
    • Neve R. L., Harris R., Kosik K. S., Kurnit D. M., and Donlon T. A. (1986) Identification of cDNA clones for the human microtubule-associated protein, tau, and chromosomal location of the genes for tau and MAP2. J. Mol. Brain Res. 1, 271-280.
    • (1986) J. Mol. Brain Res. , vol.1 , pp. 271-280
    • Neve, R.L.1    Harris, R.2    Kosik, K.S.3    Kurnit, D.M.4    Donlon, T.A.5
  • 60
    • 0031155892 scopus 로고    scopus 로고
    • Microtubule-associated proteins (MAPs) in the peripheral nervous system during development and regeneration
    • Nuñez J. and Fischer I. (1997) Microtubule-associated proteins (MAPs) in the peripheral nervous system during development and regeneration. J. Mol. Neurosci. 8, 207-222.
    • (1997) J. Mol. Neurosci. , vol.8 , pp. 207-222
    • Nuñez, J.1    Fischer, I.2
  • 61
    • 0030786544 scopus 로고    scopus 로고
    • Frontotemporal dementia: Its rediscovery
    • Pasquier F. and Petit H. (1997) Frontotemporal dementia: its rediscovery. Eur. Neurol. 38, 1-6.
    • (1997) Eur. Neurol. , vol.38 , pp. 1-6
    • Pasquier, F.1    Petit, H.2
  • 62
    • 0025856790 scopus 로고
    • Characterization and molecular cloning of polypyrimidine tract-binding protein: A component of a complex necessary for premRNA splicing
    • Patton J. G., Mayer S. A., Tempst P., and Nadal-Ginard B. (1991) Characterization and molecular cloning of polypyrimidine tract-binding protein: a component of a complex necessary for premRNA splicing. Genes Dev. 5, 1237-1251.
    • (1991) Genes Dev. , vol.5 , pp. 1237-1251
    • Patton, J.G.1    Mayer, S.A.2    Tempst, P.3    Nadal-Ginard, B.4
  • 64
    • 0029933504 scopus 로고    scopus 로고
    • Initial splice-site recognition and pairing during pre-mRNA splicing
    • Reed R. (1996) Initial splice-site recognition and pairing during pre-mRNA splicing. Curr. Opin. Genet. Dev. 6, 215-220.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 215-220
    • Reed, R.1
  • 65
    • 0027964987 scopus 로고
    • Complete sequence of the 3′ untranslated region of tau from rat central nervous system: Implications for mRNA heterogeneity
    • Sadot E., Marx R., Barg J., Behar L., and Ginzburg I. (1994) Complete sequence of the 3′ untranslated region of tau from rat central nervous system: implications for mRNA heterogeneity. J. Mol. Biol. 241, 325-331.
    • (1994) J. Mol. Biol. , vol.241 , pp. 325-331
    • Sadot, E.1    Marx, R.2    Barg, J.3    Behar, L.4    Ginzburg, I.5
  • 68
    • 0029958035 scopus 로고    scopus 로고
    • The mammalian homolog of suppressor-of-white-apricot regulates alternative mRNA splicing of CD45 exon 4 and fibronectin IIICS
    • Sarkissian M., Winne A., and Lafyatis R. (1996) The mammalian homolog of suppressor-of-white-apricot regulates alternative mRNA splicing of CD45 exon 4 and fibronectin IIICS. J. Biol. Chem. 271, 31106-31114.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31106-31114
    • Sarkissian, M.1    Winne, A.2    Lafyatis, R.3
  • 70
    • 0028307171 scopus 로고
    • Split genes and RNA splicing
    • Sharp P. A. (1994) Split genes and RNA splicing. Cell 77, 805-815.
    • (1994) Cell , vol.77 , pp. 805-815
    • Sharp, P.A.1
  • 71
    • 0031841948 scopus 로고    scopus 로고
    • The exon splicing silencer in human immunodeficiency virus type 1 Tat exon 3 is bipartite and acts early in spliceosome assembly
    • Si Z. H., Rauch D., and Stolzfus C. M. (1998) The exon splicing silencer in human immunodeficiency virus type 1 Tat exon 3 is bipartite and acts early in spliceosome assembly. Mol. Cell. Biol. 18, 5404-5413.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5404-5413
    • Si, Z.H.1    Rauch, D.2    Stolzfus, C.M.3
  • 72
    • 0024594710 scopus 로고
    • Mutually exclusive splicing of α-tropomyosin exons enforced by an unusual lariat branch point location; implications for constitutive splicing
    • Smith C. W. J. and Nadal-Ginard B. (1989) Mutually exclusive splicing of α-tropomyosin exons enforced by an unusual lariat branch point location; implications for constitutive splicing. Cell 56, 749-758.
    • (1989) Cell , vol.56 , pp. 749-758
    • Smith, C.W.J.1    Nadal-Ginard, B.2
  • 73
    • 0343848018 scopus 로고
    • Alternative splicing in the control of gene expression
    • Kedes L. H. and Stockdale F. E., eds, Alan R. Liss, New York
    • Smith C. W. J., Patton J. G., and Nadal-Ginard B. (1989) Alternative splicing in the control of gene expression, in Cellular and Molecular Biology of Muscle Development (Kedes L. H. and Stockdale F. E., eds), pp. 573-584. Alan R. Liss, New York.
    • (1989) Cellular and Molecular Biology of Muscle Development , pp. 573-584
    • Smith, C.W.J.1    Patton, J.G.2    Nadal-Ginard, B.3
  • 74
    • 0003374626 scopus 로고    scopus 로고
    • Tau protein pathology in neurodegenerative diseases
    • Spillantini M. G. and Goedert M. (1998) Tau protein pathology in neurodegenerative diseases. Trends Neurosci. 21, 428-433.
    • (1998) Trends Neurosci. , vol.21 , pp. 428-433
    • Spillantini, M.G.1    Goedert, M.2
  • 76
    • 0028999992 scopus 로고
    • Identification of positive and negative splicing regulatory elements within the terminal tat-rev exon of human immunodeficiency virus type 1
    • Staffa A. and Cochrane A. (1995) Identification of positive and negative splicing regulatory elements within the terminal tat-rev exon of human immunodeficiency virus type 1. Mol. Cell. Biol. 15, 4597-4605.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4597-4605
    • Staffa, A.1    Cochrane, A.2
  • 77
    • 0031466966 scopus 로고    scopus 로고
    • Novel exonic elements that modulate splicing of the human fibronectin EDA exon
    • Staffa A., Acheson N. H., and Cochrane A. (1997) Novel exonic elements that modulate splicing of the human fibronectin EDA exon. J. Biol. Chem. 272, 33394-33401.
    • (1997) J. Biol. Chem. , vol.272 , pp. 33394-33401
    • Staffa, A.1    Acheson, N.H.2    Cochrane, A.3
  • 78
    • 0028282980 scopus 로고
    • A sequence compilation and comparison of exons that are alternatively spliced in neurons
    • Stamm S., Zhang M. Q., Marr T. G., and Helfman D. M. (1994) A sequence compilation and comparison of exons that are alternatively spliced in neurons. Nucleic Acids Res. 22, 1515-1526.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 1515-1526
    • Stamm, S.1    Zhang, M.Q.2    Marr, T.G.3    Helfman, D.M.4
  • 79
    • 0033593649 scopus 로고    scopus 로고
    • Regulation of the neuron-specific exon of clathrin light chain B
    • Stamm S., Casper D., Hanson V., and Helfman D. M. (1999) Regulation of the neuron-specific exon of clathrin light chain B. Mol. Brain Res. 64, 108-118.
    • (1999) Mol. Brain Res. , vol.64 , pp. 108-118
    • Stamm, S.1    Casper, D.2    Hanson, V.3    Helfman, D.M.4
  • 80
    • 0026003364 scopus 로고
    • Alternative splicing in the neural cell adhesion molecule pre-mRNA: Regulation of exon 18 skipping depends on the 5′-splice site
    • Tacke R. and Goridis C. (1991) Alternative splicing in the neural cell adhesion molecule pre-mRNA: regulation of exon 18 skipping depends on the 5′-splice site. Genes Dev. 5, 1416-1429.
    • (1991) Genes Dev. , vol.5 , pp. 1416-1429
    • Tacke, R.1    Goridis, C.2
  • 81
    • 0031282306 scopus 로고    scopus 로고
    • Post-transcriptional regulation: The dawn of PTB
    • Valcárcel J. and Gebauer F. (1997) Post-transcriptional regulation: the dawn of PTB. Curr. Biol. 7, 705-708.
    • (1997) Curr. Biol. , vol.7 , pp. 705-708
    • Valcárcel, J.1    Gebauer, F.2
  • 82
    • 0030218143 scopus 로고    scopus 로고
    • The SR protein family-pleiotropic functions in pre-mRNA splicing
    • Valcárcel J. and Green M. R. (1996) The SR protein family-pleiotropic functions in pre-mRNA splicing. Trends Biochem. Sci. 21, 296-301.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 296-301
    • Valcárcel, J.1    Green, M.R.2
  • 83
    • 0030595187 scopus 로고    scopus 로고
    • Interaction of U2AF65 RS region with pre-mRNA branch point and promotion of base pairing with U2 snRNA
    • Valcárcel J., Gaur R. K., Singh R., and Green M. R. (1996) Interaction of U2AF65 RS region with pre-mRNA branch point and promotion of base pairing with U2 snRNA. Science 273, 1706-1709.
    • (1996) Science , vol.273 , pp. 1706-1709
    • Valcárcel, J.1    Gaur, R.K.2    Singh, R.3    Green, M.R.4
  • 84
    • 0027469909 scopus 로고
    • A novel tau transcript in cultured human neuroblastoma cells expressing nuclear tau
    • Wang Y., Loomis P. A., Zinkowski R. P., and Binder L. I. (1993) A novel tau transcript in cultured human neuroblastoma cells expressing nuclear tau. J. Cell Biol. 121, 257-267.
    • (1993) J. Cell Biol. , vol.121 , pp. 257-267
    • Wang, Y.1    Loomis, P.A.2    Zinkowski, R.P.3    Binder, L.I.4
  • 85
    • 0031906031 scopus 로고    scopus 로고
    • Splicing of a regulated exon reveals additional complexity in the axonal microtubule-associated protein tau
    • Wei M.-L. and Andreadis A. (1998) Splicing of a regulated exon reveals additional complexity in the axonal microtubule-associated protein tau. J. Neurochem. 70, 1346-1356.
    • (1998) J. Neurochem. , vol.70 , pp. 1346-1356
    • Wei, M.-L.1    Andreadis, A.2
  • 86
    • 0031660618 scopus 로고    scopus 로고
    • Chromosome 17-linked dementias
    • Wilhelmsen K. C. (1998) Chromosome 17-linked dementias. Cell. Mol. Life Sci. 54, 920-924.
    • (1998) Cell. Mol. Life Sci. , vol.54 , pp. 920-924
    • Wilhelmsen, K.C.1
  • 87
    • 0028178987 scopus 로고
    • The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5′ splice site selection in vivo
    • Yang X., Bani M. R., Lu S. J., Rowan S., Ben-David Y., and Chabot B. (1994) The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5′ splice site selection in vivo. Proc. Natl. Acad. Sci. USA 91, 6924-6928.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6924-6928
    • Yang, X.1    Bani, M.R.2    Lu, S.J.3    Rowan, S.4    Ben-David, Y.5    Chabot, B.6
  • 88
    • 0027160003 scopus 로고
    • Distinct functions of sr proteins in alternative pre-mRNA splicing
    • Zahler A. M., Neubarger K. M., Lane W. S., and Roth M. B. (1993) Distinct functions of SR proteins in alternative pre-mRNA splicing. Science 260, 219-222.
    • (1993) Science , vol.260 , pp. 219-222
    • Zahler, A.M.1    Neubarger, K.M.2    Lane, W.S.3    Roth, M.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.