Magnitude of structural changes of the T-cell receptor binding regions determine the strength of T-cell antagonism: Molecular dynamics simulations of HLA-DR4 (DRB1*0405) complexed with analogue peptide

Protein Engineering

Volumn 13, Issue 6, 2000, Pages 423-429

  Toh, Hidehiro ^a   Kamikawaji, Nobuhiro ^a   Tana, Takeshi ^a   Muta, Shigeru ^a   Sasazuki, Takehiko ^a   Kuhara, Satoru ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Analogue peptide; HLA class II molecule; Molecular dynamics simulation; Recognition; T cell receptor

Indexed keywords

HLA DR4 ANTIGEN; PEPTIDE; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; HUMAN; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE;

EID: 0033939649     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/13.6.423     Document Type: Article

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