Stimulation of osteoclast differentiation in vitro by mouse oncostatin M, leukaemia inhibitory factor, cardiotrophin-1 and interleukin 6: Synergy with dexamethasone

Cytokine

Volumn 12, Issue 6, 2000, Pages 613-621

  Richards, Carl D ^a   Langdon, Carrie ^a   Deschamps, Paula ^a   Pennica, Diane ^b   Shaughnessy, Stephen G ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b GENENTECH INC   (United States)

Author keywords

Bone metabolism; Cytokines; Dexame; Osteoblasts; Osteoclasts

Indexed keywords

CARDIOTROPHIN 1; DEXAMETHASONE; INDOMETACIN; INTERLEUKIN 6; LEUKEMIA INHIBITORY FACTOR; MESSENGER RNA; ONCOSTATIN M;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CALVARIA; CELL DIFFERENTIATION; FEMALE; MOUSE; NONHUMAN; OSTEOCLAST; PRIORITY JOURNAL;

ANIMALIA; MURINAE; UNIDENTIFIED AGENTS;

EID: 0033923617     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1999.0635     Document Type: Article

References (50)

1. Martin TJ, Romas E, Gillespie MT. Interleukins in the control of osteoclast differentiation. Crit Rev Eukaryotic Gene Expression. 8:1998;107-123.
2. Suda T, Nakamura I, Jimi E, Takahashi N. Regulation of osteoclast function. J. Bone Miner Res. 12:1997;869-879.
3. Heymann D, Guicheux J, Gouin F, Passuti N, Daculsi G. Cytokines, growth factors and osteoclasts. Cytokine. 10:1998;155-168.
4. Tamura T, Udagawa N, Takahashi N, Miyaura C, Tanaka S, Yamada Y, Koishihara Y, Ohsugi Y, Kumaki K, Taga T, Kishimoto T, Suda T. Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6. Proc Natl Acad Sci USA. 90:1993;11924-11928.
5. Ishimi Y, Miyaura C, Jin CH, Akatsu T, Abe E, Nakamura Y, Yamaguchi A, Yoshiki S, Matsuda T, Hirano T, Kishimoto T, Suda T. IL-6 is produced by osteoblasts and induces bone resporption. J Immunol. 145:1990;3297-3303.
6. Jilka RL, Hangoc G, Girasole G, Passeri G, Williams DC, Manolagas SC. Increased osteoclast development after estrogen loss:mediation by interleukin-6. Science. 257:1992;88-91.
7. Reid IR, Lowe C, Cornish J, Skinner JM, Hilton DJ, Willson TA, Gearing DP, Martin TJ. Leukemia inhibitory factor: a novel bone-active cytokine. Endocrinology. 126:1990;1416-1420.
8. Girasole G, Passeri G, Jilka RL, Manolagas SC. Interleukin-11: a new cytokine critical for osteoclast development. J Clin Invest. 93:1994;1516-1524.
9. Jay PR, Centrella M, Lorenzo J, Bruce AG, Horowitz MC. Oncostatin-M: a new bone active cytokine that activates osteoblasts and inhibits bone resorption. Endocrinology. 137:1996;1151.
10. Lorenzo JA, Sousa SL, Leahy CL. Leukemia inhibitory factor (LIF) inhibits basal bone resorption in fetal rat long bone cultures. Cytokine. 2:1990;266-271.
11. Yoshimura A, Ichihara M, Kinjyo I, Moriyama M, Copeland NG, Gilbert DJ, Jenkins NA, Hara T, Miyajima A. Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway. EMBO J. 15:1996;1055-1063.
12. Ichihara M, Kim H, Murate T, Miyajima A. Oncostatin M and leukemia inhibitory factor do not use the same functional receptor in mice. Blood. 90:1997;165-173.
13. Richards CD, Kerr C, Tanaka M, Hara T, Miyajima A, Pennica D, Botelho F, Langdon CM. Regulation of tissue inhibitor of metalloproteinase-1 in fibroblasts and acute phase proteins in hepatocytes in vitro by mouse oncostatin M, cardiotrophin-1, and IL-6. J Immunol. 159:1997;2431-2437.
14. Lindberg RA, Juan TSC, Welcher AA, Sun Y, Cupples R, Guthrie B, Fletcher FA. Cloning and characterization of a specific receptor for mouse oncostatin M. Mol Cell Biol. 18:1998;3357-3367.
15. Akatsu T, Takahashi N, Udagawa N, Imamura K, Yamaguchi A, Sato K, Nagata N, Suda T. Role of prostaglandins in interleukin-1-induced bone resorption in mice in vitro. J Bone Miner. 6:1991;183-190.
16. Geisterfer M, Richards C, Gauldie J. Cytokines oncostatin M and interleukin 1 regulate the expression of the IL-6 receptor (gp80, gp130). Cytokine. 7:1995;503-509.
17. Cichy J, Rose-John S, Potempa J, Pryjma J, Travis J. Oncostatin M stimulates the expression and release of the IL-6 receptor in human hepatoma hepG2 cells. J Immunol. 159:1997;5648-5653.
18. Brown TJ, Rowe JM, Liu J, Shoyab M. Regulation of interleukin-6 expression by oncostatin M. J Immunol. 147:1991;2175-2180.
19. 2in induction of IL-6 expression in human fibroblasts. Cytokine. 6:1994;40-47.
20. Littlewood AJ, Russell J, Harvey GR, Hughes DE, Russell RGG, Gowen M. The modulation of the expression of IL-6 and its receptor in human osteoblasts in vitro. Endocrinology. 129:1991;1513-1520.
21. Bellido T, Borba VZC, Roberson P, Manolagas SC. Activation of the janus kinase/STAT (signal transducer and activator of transcription) signal transduction pathway by interleukin-6type cytokines promotes osteoblast differentiation. Endocrinology. 138:1997;3666-3676.
22. Ray A, Prefontaine KE, Ray P. Down-modulation of interleukin-6 gene expression by 17β-estradiol in the absence of high affinity binding by the estrogen receptor. J Biol Chem. 269:1998;12940-12946.
23. Ray P, Ghosh SK, Zhang D, Ray A. Repression of interleukin-6 gene expression by 17β-estradiol: inhibition of the DNA-binding activity of the transcription factors NF-1L-6 and NFκB by the estrogen receptor. FEBS Letts. 409:1997;79-85.
24. Heymann D, Guicheux J, Gouin F, Cottrel M, Daculsi G. Oncostatin M stimulates macrophage-polykaryon formation in long-term human bone-marrow cultures. Cytokine. 10:1998;98-109.
25. Schooltink H, Schmitz-Van de Leur H, Heinrich PC, Rose-John S. Up-regulation of the interleukin-6-signal transducing protein (gp130) by interleukin-6 and dexamethasone in HepG2 cells. FEBS Letts. 297:1992;263-265.
26. Udagawa N, Takahashi N, Katagiri T, Tamura T, Wada S, Findlay DM, Martin TJ, Hirota H, Taga T, Kishimoto TJ, Suda T. Interleukin (IL)-6 induction of osteoclasts differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors. J Exp Med. 182:1995;1461-1468.
27. Murakami-Mori K, Mori S, Tetsuya T, Kishimoto T, Nakamura S. Enhancement of gp130-mediated tyrosine phosphorylation of STAT3 and its DNA-binding activity in dexamethasone-treated AIDS-associated Kaposi's sarcoma cells. J Immunol. 158:1997;5518-5526.
28. 3or parathyroid hormone. J Biol Chem. 274:1999;19301-19308.
29. Yasuda H, Shima N, Nakagawa N, Yamaguchi K, Kinosaki M, Mochizuki S, Tomoyasu A, Yano K, Goto M, Murakami A, Tsuda E, Morinaga T, Higashio K, Udagawa N, Takahashi N, Suda T. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA. 95:1998;3597-3602.
30. Lacey DL, Timms E, Tan H-L, Kelley MJ, Dunstan CR, Burgess T, Elliott R, Colombero A, Elliott G, Scully S, Hsu H, Sullivan J, Hawkins N, Davy E, Capparelli C, Eli A, Qian Y-X, Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, Delaney J, Boyle WJ. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell. 93:1998;165-176.
31. Wong BR, Josien R, Choi Y. TRANCE is a TNF family member that regulates dendritic cell and osteoclast function. J Leukoc Biol. 65:1999;715-724.
32. Simonet WS, Lacey DL, Dunstan CR, Kelley M, Chang M-S, Luthy R, Nguyen HQ, Wooden S, Bennett L, Boone T, Shimamoto G, DeRose M, Elliott R, Colombero A, Tan H-L, Trail G, Sullivan J, Davy E, Bucay N, Renshaw-Greg L, Hughes TM, Hill D, Pattison W, Campell P, Sander S, Van G, Tarpley J, Derby P, Lee R, Boyle WJ. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell. 89:1997;309-319.
33. Auguste P, Guillet C, Fourcin M, Olivier C, Veziers J. Signaling of type II oncostatin M receptor. J Biol Chem. 272:1997;15760-15764.
34. Botelho F, Edwards D, Richards CD. Oncostatin M stimulates c-Fos to bind a transcriptionally responsive AP-1 element within the tissue inhibitor of metalloproteinase-1 promoter. J Biol Chem. 273:1998;5211-5218.
35. Pennica D, King KL, Shaw KJ, Luis E, Rullamas J, Luoh S, Darbonne WC, Knutzon DS, Yen R, Chien KR, Baker JB, Wood WI. Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy. Proc Natl Acad Sci USA. 92:1995;1142-1146.
36. Pennica D, Wood WI, Chien KR. Cardiotrophin-1: a multifunctional cytokine that signals via lif receptor-gp130 dependent pathways. Cyt Growth Fact Rev. 7:1996;81-91.
37. Pennica D, Shaw KJ, Swanson TA, Moore MW, Shelton DL, Zioncheck KA, Rosenthal A, Taga T, Paoni NF, Wood WL. Cardiotropin-1: biological activities and binding to the leukemia inhibitory factor receptor/gp130 signalling complex. J Biol Chem. 270:1995;10915-10922.
38. Romas E, Udagawa N, Zhou H, Tamura T, Saito M, Taga T, Hilton DJ, Suda T, Ng KW, Martin TJ. The role of gp130-mediated signals in osteoclast development: regulation of interleukin 11 production by osteoblasts and distribution of its receptor in bone marrow cultures. J Exp Med. 183:1996;2581-2591.
39. Haynesworth SE, Baber MA, Caplan AI. Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: effects of dexamethasone and IL-1α J Cell Physiol. 166:1996;585-592.
40. Onoe Y, Miyaura C, Kaminakayashiki T, Nagai Y, Noguchi K, Chen Q, Seo H, Ohta H, Nozawa S, Kudo I, Suda T. IL-13 and IL-4 inhibit bone resorption by suppressing cyclooxygenase-2-dependent prostaglandin synthesis in osteoblasts. J Immunol. 156:1996;758-764.
41. Tang K, Capparelli C, Stein JL, Stein GS, Lian JB, Huber AC, Braverman LE, DeVito WJ. Acidic fibroblast growth factor inhibits osteoblast differentiation in vitro: altered expression of collagenase, cell growth-related, and mineralization-associated genes. J Cell Biochem. 61:1996;152-166.
42. Breen EC, Ignotz RA, McCabe L, Stein JL, Stein GS, Lian JB. TGFβ alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype. J Cell Physiology. 160:1998;323-335.
43. Bennet A, Chen T, Feldman D, Hintz R, Roesenfeld RG. Characterization of insulin-like growth factor receptors on cultured rat bone cells:regulation of receptor concentration by glucocorticoids. Endocrinology. 115:1984;1577-1583.
44. Wada S, Akatsu T, Tamura T, Takahashi N, Suda T, Nagata N. Glucocorticoid regulation of calcitonin receptor in mouse osteoclast-like multinucleated cells. J Bone Miner Res. 9:1994;1705-1712.
45. Delany AM, Jeffrey JJ, Rydziel S, Canalis E. Cortisol increases interstitial collagenase expression in osteoblasts by post-transcriptional mechanisms. J Biol Chem. 270:1995;26607-26612.
46. Weinstein RS, Jilka RL, Parfitt AM, Manolagas SC. Inhibition of osteoblastogenesis and promotion of apoptosis of osyteoblasts and osteocytes by glucocorticoids: possible mechanisms of their deleterious effects on bone. J Clin Invest. 102:1998;274-282.
47. Richards C, Langdon C, Pennica D, Gauldie J. Murine cardiotrophin-1 stimulates the acute-phase response in rat hepatocytes and H35 hepatoma cells. J Interferon Cytokine Res. 16:1996;69-75.
48. Aarden LA, De Groot ER, Schaap OL, Lansdorp PM. Production of hybridoma growth factor by human monocytes. Eur J Immunol. 17:1987;1411-1416.
49. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 65:1983;55-63.
50. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:1987;156-159.