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Volumn 30, Issue 6, 2000, Pages 619-625

An inhibitory monoclonal antibody to human cytochrome P450 that specifically binds and inhibits P4502C9II, an allelic variant of P4502C9 having a single amino acid change Arg144 Cys

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DICLOFENAC; MONOCLONAL ANTIBODY; PHENANTHRENE; TOLBUTAMIDE;

EID: 0033922921     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/004982500406444     Document Type: Article
Times cited : (7)

References (31)
  • 1
    • 0023354424 scopus 로고    scopus 로고
    • Expression of P1-450 and P3-450 DNA coding sequences as enzymatically active cytochromes P-450 in mammalian cells
    • BATTULA, N., SAGARA, J. and GELBOIN, H. V., 1987, Expression of P1-450 and P3-450 DNA coding sequences as enzymatically active cytochromes P-450 in mammalian cells. Proceedings of the National Academy of Sciences, USA, 12, 4073-4077.
    • Proceedings of the National Academy of Sciences, USA , vol.12 , pp. 4073-4077
    • Battula, N.1    Sagara, J.2    Gelboin, H.V.3
  • 2
    • 0030627339 scopus 로고    scopus 로고
    • Use of cDNA-expressed human cytochrome P450 enzymes to study potential drug-drug interactions
    • CRESPI, C. L. AND PENMAN, B. W., 1997, Use of cDNA-expressed human cytochrome P450 enzymes to study potential drug-drug interactions. Advances in Pharmacology, 43, 171-188.
    • (1997) Advances in Pharmacology , vol.43 , pp. 171-188
    • Crespi, C.L.1    Penman, B.W.2
  • 4
    • 0027759647 scopus 로고
    • Monoclonal antibodies and cytochrome P450
    • GELBOIN, H. V., 1993, Monoclonal antibodies and cytochrome P450. Pharmacological Reviews, 45, 413-453.
    • (1993) Pharmacological Reviews , vol.45 , pp. 413-453
    • Gelboin, H.V.1
  • 8
    • 0030661662 scopus 로고    scopus 로고
    • A monoclonal antibody inhibitory to human P450 2D6: A paradigm for use in combinatorial determination of individual P450 role in specific drug tissue metabolism
    • GELBOIN, H. V., KRAUSZ, K. W., SHOU, M., GONZALEZ, F. J. and YANG, T. J., 1997, A monoclonal antibody inhibitory to human P450 2D6: a paradigm for use in combinatorial determination of individual P450 role in specific drug tissue metabolism. Pharmacogenetics, 7, 469-477.
    • (1997) Pharmacogenetics , vol.7 , pp. 469-477
    • Gelboin, H.V.1    Krausz, K.W.2    Shou, M.3    Gonzalez, F.J.4    Yang, T.J.5
  • 11
    • 0030587544 scopus 로고    scopus 로고
    • Allelic variants of human cytochrome P450 2C9: Baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms
    • HAINING, R. L., HUNTER, A. P., VERONESE, M. E., TRAGER, W. F. and RETTIE, A. E., 1996, Allelic variants of human cytochrome P450 2C9: baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms. Archives of Biochemistry and Biophysics, 333, 447-458.
    • (1996) Archives of Biochemistry and Biophysics , vol.333 , pp. 447-458
    • Haining, R.L.1    Hunter, A.P.2    Veronese, M.E.3    Trager, W.F.4    Rettie, A.E.5
  • 12
    • 0032793249 scopus 로고    scopus 로고
    • Polymorphic human cytochrome P450 enzymes: An opportunity for individualized drug treatment
    • INGELMAN-SUNDBERG, M., OSCARSON, M. and MCLELLAN, R. A., 1999, Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment. Trends in Pharmacological Sciences, 20, 342-349.
    • (1999) Trends in Pharmacological Sciences , vol.20 , pp. 342-349
    • Ingelman-Sundberg, M.1    Oscarson, M.2    McLellan, R.A.3
  • 14
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • KOHLER, G. and MILSTEIN, C., 1975, Continuous cultures of fused cells secreting antibody of predefined specificity. Nature, 7, 495-497.
    • (1975) Nature , vol.7 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 15
    • 0031841377 scopus 로고    scopus 로고
    • Cytochrome P 450 2C9: An enzyme of major importance in human drug metabolism
    • MINERS, J. O. and BIRKETT, D. J. 1998, Cytochrome P 450 2C9: an enzyme of major importance in human drug metabolism. British Journal of Clinical Pharmacology, 45, 525-538.
    • (1998) British Journal of Clinical Pharmacology , vol.45 , pp. 525-538
    • Miners, J.O.1    Birkett, D.J.2
  • 17
    • 0030868490 scopus 로고    scopus 로고
    • Genetic analysis of CYP2C9 polymorphism in a Japanese population
    • NASU, K., KUBOTA, T. and ISHIZAKI, T., 1997, Genetic analysis of CYP2C9 polymorphism in a Japanese population. Pharmacogenetics, 7, 405-409.
    • (1997) Pharmacogenetics , vol.7 , pp. 405-409
    • Nasu, K.1    Kubota, T.2    Ishizaki, T.3
  • 19
    • 0030834058 scopus 로고    scopus 로고
    • Human cytochrome P450 enzymes: Status report summarizing their reactions, substrates, inducers, and inhibitors
    • RENDIC, S. and DI CARLO, F. J., 1997, Human cytochrome P450 enzymes: status report summarizing their reactions, substrates, inducers, and inhibitors. Drug Metabolism Reviews, 29, 413-580.
    • (1997) Drug Metabolism Reviews , vol.29 , pp. 413-580
    • Rendic, S.1    Di Carlo, F.J.2
  • 21
    • 0032812611 scopus 로고    scopus 로고
    • An inhibitory monoclonal antibody to human cytochrome P450 2A6 defines its role in the metabolism of coumarin, 7-ethoxycoumarin and 4-nitroanisole in human liver
    • SAI, Y., YANG, T. J., KRAUSZ, K. W., GONZALEZ, F. J. and GELBOIN, H. V., 1999, An inhibitory monoclonal antibody to human cytochrome P450 2A6 defines its role in the metabolism of coumarin, 7-ethoxycoumarin and 4-nitroanisole in human liver. Pharmacogenetics, 9, 229-237.
    • (1999) Pharmacogenetics , vol.9 , pp. 229-237
    • Sai, Y.1    Yang, T.J.2    Krausz, K.W.3    Gonzalez, F.J.4    Gelboin, H.V.5
  • 22
    • 0028085833 scopus 로고
    • Regio- and stereo-selective metabolism of phenanthrene by twelve cDNA expressed human, rodent, and rabbit cytochromes P-450
    • SHOU, M., KORZEKWA, K. R., KRAUSZ, K. W., CRESPI, C. L., GONZALEZ, F. J. and GELBOIN, H. V., 1994, Regio- and stereo-selective metabolism of phenanthrene by twelve cDNA expressed human, rodent, and rabbit cytochromes P-450. Cancer Letters, 83, 305-313.
    • (1994) Cancer Letters , vol.83 , pp. 305-313
    • Shou, M.1    Korzekwa, K.R.2    Krausz, K.W.3    Crespi, C.L.4    Gonzalez, F.J.5    Gelboin, H.V.6
  • 27
    • 0031757521 scopus 로고    scopus 로고
    • Comparative studies on the catalytic roles of cytochrome P450 2C9 and its Cys- and Leu-variants in the oxidation of warfarin, flurbiprofen, and diclofenac by human liver microsomes
    • YAMAZAKI, H., INOUE, K., CHIBA, K., OZAWA, N., KAWAI, T., SUZUKI, Y., GOLDSTEIN, J. A., GUENGERICH, F. P. and SHIMADA, T., 1998, Comparative studies on the catalytic roles of cytochrome P450 2C9 and its Cys- and Leu-variants in the oxidation of warfarin, flurbiprofen, and diclofenac by human liver microsomes. Biochemical Pharmacology, 56, 243-251.
    • (1998) Biochemical Pharmacology , vol.56 , pp. 243-251
    • Yamazaki, H.1    Inoue, K.2    Chiba, K.3    Ozawa, N.4    Kawai, T.5    Suzuki, Y.6    Goldstein, J.A.7    Guengerich, F.P.8    Shimada, T.9
  • 29
    • 0033010360 scopus 로고    scopus 로고
    • Eight inhibitory monoclonal antibodies define the role of individual P450s in human liver microsomal diazepam, 7-ethoxycoumarin and imipramine metabolism
    • YANG, T. J., KRAUSZ, K. W., SAI, Y., GONZALEZ, F. J. and GELBOIN, H. V., 1999, Eight inhibitory monoclonal antibodies define the role of individual P450s in human liver microsomal diazepam, 7-ethoxycoumarin and imipramine metabolism. Drug Metabolism and Disposition, 27, 102-109.
    • (1999) Drug Metabolism and Disposition , vol.27 , pp. 102-109
    • Yang, T.J.1    Krausz, K.W.2    Sai, Y.3    Gonzalez, F.J.4    Gelboin, H.V.5
  • 30
    • 0031717524 scopus 로고    scopus 로고
    • Inhibitory monoclonal antibodies to human cytochrome P450 1A2: Analysis of phenacetin o-deethylation in human liver
    • YANG, T. J., SAI, Y., KRAUSZ, K. W., GONZALEZ, F. J. and GELBOIN, H. V., 1998b, Inhibitory Monoclonal Antibodies to Human cytochrome P450 1A2: analysis of phenacetin o-deethylation in human liver. Pharmacogenetics, 8, 375-382.
    • (1998) Pharmacogenetics , vol.8 , pp. 375-382
    • Yang, T.J.1    Sai, Y.2    Krausz, K.W.3    Gonzalez, F.J.4    Gelboin, H.V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.