An inhibitory monoclonal antibody to human cytochrome P450 2A6 defines its role in the metabolism of coumarin, 7-ethoxycoumarin and 4-nitroanisole in human liver

Pharmacogenetics

Volumn 9, Issue 2, 1999, Pages 229-237

  Sai, Yang ^a   Jian Yang, Tian ^a   Krausz, Kristopher W ^a   Gonzalez, Frank J ^b   Gelboin, Harry V ^a,b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

4 Nitroanisole; 4 Nitrophenol; 7 Ethoxycoumarin; Coumarin; Human CYP2A6; Human liver microsomes; Inhibitory monoclonal antibody; Phenanthrene

Indexed keywords

4 NITROANISOLE; 4 NITROPHENOL; 7 ETHOXYCOUMARIN; COUMARIN; CYTOCHROME P450; MONOCLONAL ANTIBODY; PHENANTHRENE; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CROSS REACTION; DRUG METABOLISM; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; HYBRIDOMA; IMMUNIZATION; IMMUNOBLOTTING; LIVER METABOLISM; LIVER MICROSOME; MOUSE; MYELOMA CELL; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; SPLEEN CELL;

ANIMALS; ANISOLES; ANTIBODIES, MONOCLONAL; ARYL HYDROCARBON HYDROXYLASES; CATALYSIS; COUMARINS; CROSS REACTIONS; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HUMANS; HYBRIDOMAS; MICE; MICE, INBRED BALB C; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES;

ANIMALIA; UNIDENTIFIED BACULOVIRUS;

EID: 0032812611     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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