Inhibitory monoclonal antibodies to human cytochrome P450 1A2: Analysis of phenacetin O-deethylation in human liver

Pharmacogenetics

Volumn 8, Issue 5, 1998, Pages 375-382

  Yang, Tian J ^a   Sai, Yang ^a   Krausz, Kristopher W ^a   Gonzalez, Frank J ^a   Gelboin, Harry V ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

2A6; 2C19; Human Liver microsomes; Human P450 1A2; Inhibitory monoclonal antibodies; Phenacetin 0 deethylation

Indexed keywords

7 ETHOXYCOUMARIN; CAFFEINE; CARCINOGEN; CHLORZOXAZONE; CLOMIPRAMINE; CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; ENVIRONMENTAL CHEMICAL; ETHOXYCOUMARIN; MONOCLONAL ANTIBODY; MUTAGENIC AGENT; PARAXANTHINE; PHENACETIN; PHENACETIN O DEETHYLASE; PHENANTHRENE; RESORUFIN; THEOBROMINE; THEOPHYLLINE; WARFARIN;

ANTIBODY SPECIFICITY; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME POLYMORPHISM; HUMAN; HUMAN CELL; HYBRIDOMA; IMMUNOBLOTTING; LIVER MICROSOME; PHARMACOGENETICS; PRIORITY JOURNAL; PROTEIN CONTENT;

ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; ISOENZYMES; LIVER; MICROSOMES, LIVER; PHENACETIN; PHENANTHRENES; SUBSTRATE SPECIFICITY;

EID: 0031717524     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199810000-00002     Document Type: Article

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