A monoclonal antibody inhibitory to human P450 2D6: A paradigm for use in combinatorial determination of individual P450 role in specific drug tissue metabolism

Pharmacogenetics

Volumn 7, Issue 6, 1997, Pages 469-477

  Gelboin, H V ^a   Krausz, K W ^a   Shou, M ^a   Gonzalez, F J ^a   Yang, T J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Bufuralol; Dextromethorphan; Human P40 2D6; Inhibitory monoclonal antibodies; P450 2C8 9 19; P450 function in human tissue

Indexed keywords

BUFURALOL; CYTOCHROME P450 ISOENZYME; DEXTROMETHORPHAN; MONOCLONAL ANTIBODY; OXYGENASE; PHENANTHRENE;

ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; LIVER MICROSOME; PRIORITY JOURNAL;

EID: 0030661662     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199712000-00005     Document Type: Article

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