-
1
-
-
0025355830
-
Disposition of pravastatin sodium, a tissue-selective HMG-CoA reductase inhibitor, in healthy subjects
-
1. Singhvi SM, Pan HY, Morrison RA, Willard DA (1990) Disposition of pravastatin sodium, a tissue-selective HMG-CoA reductase inhibitor, in healthy subjects. Br J Clin Pharmacol 29: 239-243
-
(1990)
Br J Clin Pharmacol
, vol.29
, pp. 239-243
-
-
Singhvi, S.M.1
Pan, H.Y.2
Morrison, R.A.3
Willard, D.A.4
-
2
-
-
0026694388
-
Pharmacokinetics of fluvastatin after single and multiple doses in normal volunteers
-
2. Tse FL, Jaffe JM, Troendle A (1992) Pharmacokinetics of fluvastatin after single and multiple doses in normal volunteers. J Clin Pharmacol 32: 630-638
-
(1992)
J Clin Pharmacol
, vol.32
, pp. 630-638
-
-
Tse, F.L.1
Jaffe, J.M.2
Troendle, A.3
-
3
-
-
0028168962
-
Clinical pharmacokinetics of pravastatin
-
3. Quion JA, Jones PH (1994) Clinical pharmacokinetics of pravastatin. Clin Pharmacokinet 27: 94-103
-
(1994)
Clin Pharmacokinet
, vol.27
, pp. 94-103
-
-
Quion, J.A.1
Jones, P.H.2
-
4
-
-
0008551902
-
Selective in vitro P450 inhibition profile by fluvastatin indicates its potential in vivo drug interactions
-
4. Transon C, Leemann T, Dayer P (1993) Selective in vitro P450 inhibition profile by fluvastatin indicates its potential in vivo drug interactions. Clin Pharmacol Ther 53: 188
-
(1993)
Clin Pharmacol Ther
, vol.53
, pp. 188
-
-
Transon, C.1
Leemann, T.2
Dayer, P.3
-
6
-
-
0032937343
-
The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: Effect on human cytochrome P-450 and implications for metabolic drug interactions
-
6. Fischer V, Johanson L, Heitz F, Tullman R, Graham E, Baldeck JP, Robinson WT (1999) The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: effect on human cytochrome P-450 and implications for metabolic drug interactions. Drug Metab Dispos 27: 410-416
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 410-416
-
-
Fischer, V.1
Johanson, L.2
Heitz, F.3
Tullman, R.4
Graham, E.5
Baldeck, J.P.6
Robinson, W.T.7
-
7
-
-
0025771262
-
Biotransformation of pravastatin sodium in humans
-
7. Everett DW, Chando TJ, Didonato GC, Singhvi SM, Pan HY, Weinstein SH (1991) Biotransformation of pravastatin sodium in humans. Drug Metab Dispos 19: 740-748
-
(1991)
Drug Metab Dispos
, vol.19
, pp. 740-748
-
-
Everett, D.W.1
Chando, T.J.2
Didonato, G.C.3
Singhvi, S.M.4
Pan, H.Y.5
Weinstein, S.H.6
-
8
-
-
0032911163
-
Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver
-
8. Jacobsen W, Kirchner G, Hallensleben K, Mancinelli L, Deters M, Hackbarth I, Benet LZ, Sewing KF, Christians U (1999) Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver. Drug Metab Dispos 27: 173-179
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 173-179
-
-
Jacobsen, W.1
Kirchner, G.2
Hallensleben, K.3
Mancinelli, L.4
Deters, M.5
Hackbarth, I.6
Benet, L.Z.7
Sewing, K.F.8
Christians, U.9
-
9
-
-
0023924549
-
In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sulphonamides and quinolines
-
9. Back DJ, Tjia JF, Karbwang J, Colbert J (1988) In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sulphonamides and quinolines. Br J Clin Pharmacol 26: 23-29
-
(1988)
Br J Clin Pharmacol
, vol.26
, pp. 23-29
-
-
Back, D.J.1
Tjia, J.F.2
Karbwang, J.3
Colbert, J.4
-
10
-
-
0000732707
-
Effect of azole antifungals on human microsomal metabolism of diclofenac and midazolam
-
175P
-
10. Hargreaves JA, Jezequel A, Houston JB (1994) Effect of azole antifungals on human microsomal metabolism of diclofenac and midazolam. Br J Clin Pharmacol 38: 175P
-
(1994)
Br J Clin Pharmacol
, vol.38
-
-
Hargreaves, J.A.1
Jezequel, A.2
Houston, J.B.3
-
11
-
-
0029877219
-
Warfarin-fluconazole. I. Inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: In vitro studies
-
11. Kunze KL, Wienkers LC, Thummel KE, Trager WF (1996) Warfarin-fluconazole. I. Inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: in vitro studies. Drug Metab Dispos 24: 414-421
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 414-421
-
-
Kunze, K.L.1
Wienkers, L.C.2
Thummel, K.E.3
Trager, W.F.4
-
12
-
-
0025760346
-
Effect of fluconazole on the disposition of phenytoin
-
12. Blum RA, Wilton JH, Hilligoss DM, Gardner MJ, Henry EB, Harrison NJ, Schentag JJ (1991) Effect of fluconazole on the disposition of phenytoin. Clin Pharmacol Ther 49: 420-425
-
(1991)
Clin Pharmacol Ther
, vol.49
, pp. 420-425
-
-
Blum, R.A.1
Wilton, J.H.2
Hilligoss, D.M.3
Gardner, M.J.4
Henry, E.B.5
Harrison, N.J.6
Schentag, J.J.7
-
13
-
-
0029996292
-
Warfarin-fluconazole. II. A metabolically based drug interaction: In vivo studies
-
13. Black DJ, Kunze KL, Wienkers LC, Gidal BE, Seaton TL, McDonnell ND, Evans JS, Bauwens JE, Trager WF (1996) Warfarin-fluconazole. II. A metabolically based drug interaction: in vivo studies. Drug Metab Dispos 24: 422-428
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 422-428
-
-
Black, D.J.1
Kunze, K.L.2
Wienkers, L.C.3
Gidal, B.E.4
Seaton, T.L.5
McDonnell, N.D.6
Evans, J.S.7
Bauwens, J.E.8
Trager, W.F.9
-
14
-
-
0028568243
-
Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole
-
14. Varhe A, Olkkola KT, Neuvonen PJ (1994) Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole. Clin Pharmacol Ther 56: 601-607
-
(1994)
Clin Pharmacol Ther
, vol.56
, pp. 601-607
-
-
Varhe, A.1
Olkkola, K.T.2
Neuvonen, P.J.3
-
15
-
-
0029981350
-
Fluconazole, but not terbinafine, enhances the effects of triazolam by inhibiting its metabolism
-
15. Varhe A, Olkkola KT, Neuvonen PJ (1996) Fluconazole, but not terbinafine, enhances the effects of triazolam by inhibiting its metabolism. Br J Clin Pharmacol 41: 319-323
-
(1996)
Br J Clin Pharmacol
, vol.41
, pp. 319-323
-
-
Varhe, A.1
Olkkola, K.T.2
Neuvonen, P.J.3
-
16
-
-
0029664974
-
The effects of the systemic antimycotics, itraconazole and fluconazole, on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam
-
16. Olkkola KT, Ahonen J, Neuvonen PJ (1996) The effects of the systemic antimycotics, itraconazole and fluconazole, on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam. Anesth Analg 82: 511-516
-
(1996)
Anesth Analg
, vol.82
, pp. 511-516
-
-
Olkkola, K.T.1
Ahonen, J.2
Neuvonen, P.J.3
-
17
-
-
0026088892
-
Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. I. Efficacy in modifying plasma lipoproteins and adverse event profile in 8245 patients with moderate hypercholesterolemia
-
17. Bradford RH, Shear CL, Chremos AN, Dujovne C, Downton M, Franklin FA, Gould AL, Hesney M, Higgins J, Hurley DP (1991) Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. I. Efficacy in modifying plasma lipoproteins and adverse event profile in 8245 patients with moderate hypercholesterolemia. Arch Intern Med 151: 43-49
-
(1991)
Arch Intern Med
, vol.151
, pp. 43-49
-
-
Bradford, R.H.1
Shear, C.L.2
Chremos, A.N.3
Dujovne, C.4
Downton, M.5
Franklin, F.A.6
Gould, A.L.7
Hesney, M.8
Higgins, J.9
Hurley, D.P.10
-
18
-
-
18844469085
-
Expanded clinical evaluation of lovastatin (EXCEL) study results: IV. Additional perspectives on the tolerability of lovastatin
-
18. Dujovne CA, Chremos AN, Pool JL, Schnaper H, Bradford RH, Shear CL, Higgins J, Downton M, Franklin FA, Nash DT (1991) Expanded clinical evaluation of lovastatin (EXCEL) study results: IV. Additional perspectives on the tolerability of lovastatin. Am J Med 91: 25S-30S
-
(1991)
Am J Med
, vol.91
-
-
Dujovne, C.A.1
Chremos, A.N.2
Pool, J.L.3
Schnaper, H.4
Bradford, R.H.5
Shear, C.L.6
Higgins, J.7
Downton, M.8
Franklin, F.A.9
Nash, D.T.10
-
19
-
-
0003194008
-
Rhabdomyolysis seen with simvastatin 160 mg
-
19. Anonymous (1997) Rhabdomyolysis seen with simvastatin 160 mg. Reactions 653: 2
-
(1997)
Reactions
, vol.653
, pp. 2
-
-
-
20
-
-
0031717471
-
An automated method for the simultaneous determination of pravastatin and its main metabolite in human plasma by high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry
-
20. Kawabata K, Matsushima N, Sasahara K (1998) An automated method for the simultaneous determination of pravastatin and its main metabolite in human plasma by high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry. Biomed Chromatogr 12: 271-275
-
(1998)
Biomed Chromatogr
, vol.12
, pp. 271-275
-
-
Kawabata, K.1
Matsushima, N.2
Sasahara, K.3
-
21
-
-
0024601252
-
Assay of fluconazole by megabore capillary gas-liquid chromatography with nitrogen-selective detection
-
21. Harris SC, Wallace JE, Foulds G, Rinaldi MG (1989) Assay of fluconazole by megabore capillary gas-liquid chromatography with nitrogen-selective detection. Antimicrob Agents Chemother 33: 714-716
-
(1989)
Antimicrob Agents Chemother
, vol.33
, pp. 714-716
-
-
Harris, S.C.1
Wallace, J.E.2
Foulds, G.3
Rinaldi, M.G.4
-
22
-
-
0026729632
-
Determination of fluconazole in human serum by solid-phase extraction and reversed-phase high-performance liquid chromatography
-
22. Inagaki K, Takagi J, Lor E, Okamoto MP, Gill MA (1992) Determination of fluconazole in human serum by solid-phase extraction and reversed-phase high-performance liquid chromatography. Ther Drug Monit 14: 306-311
-
(1992)
Ther Drug Monit
, vol.14
, pp. 306-311
-
-
Inagaki, K.1
Takagi, J.2
Lor, E.3
Okamoto, M.P.4
Gill, M.A.5
-
23
-
-
0031954328
-
Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid
-
23. Kantola T, Kivistö KT, Neuvonen PJ (1998) Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid. Clin Pharmacol Ther 63: 397-402
-
(1998)
Clin Pharmacol Ther
, vol.63
, pp. 397-402
-
-
Kantola, T.1
Kivistö, K.T.2
Neuvonen, P.J.3
-
24
-
-
0026598851
-
Small intestinal cytochromes P450
-
24. Kaminsky LS, Fasco MJ (1992) Small intestinal cytochromes P450. Crit Rev Toxicol 21: 407-422
-
(1992)
Crit Rev Toxicol
, vol.21
, pp. 407-422
-
-
Kaminsky, L.S.1
Fasco, M.J.2
-
25
-
-
0027996327
-
Terfenadine metabolism in human liver. In vitro inhibition by macrolide antibiotics and azole antifungals
-
25. Jurima-Romet M, Crawford K, Cyr T, Inaba T (1994) Terfenadine metabolism in human liver. In vitro inhibition by macrolide antibiotics and azole antifungals. Drug Metab Dispos 22: 849-857
-
(1994)
Drug Metab Dispos
, vol.22
, pp. 849-857
-
-
Jurima-Romet, M.1
Crawford, K.2
Cyr, T.3
Inaba, T.4
-
26
-
-
0031803373
-
Different effects of itraconazole on the pharmacokinetics of fluvastatin and lovastatin
-
26. Kivistö KT, Kantola T, Neuvonen PJ (1998) Different effects of itraconazole on the pharmacokinetics of fluvastatin and lovastatin. Br J Clin Pharmacol 46: 49-53
-
(1998)
Br J Clin Pharmacol
, vol.46
, pp. 49-53
-
-
Kivistö, K.T.1
Kantola, T.2
Neuvonen, P.J.3
-
27
-
-
0031736655
-
Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: Are the statins mechanistically similar?
-
27. Christians U, Jacobsen W, Floren LC (1998) Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar? Pharmacol Ther 80: 1-34
-
(1998)
Pharmacol Ther
, vol.80
, pp. 1-34
-
-
Christians, U.1
Jacobsen, W.2
Floren, L.C.3
-
28
-
-
0031980141
-
A model for the prediction of digoxin-drug interactions at the renal tubular cell level
-
28. Woodland C, Ito S, Koren G (1998) A model for the prediction of digoxin-drug interactions at the renal tubular cell level. Ther Drug Monit 20: 134-138
-
(1998)
Ther Drug Monit
, vol.20
, pp. 134-138
-
-
Woodland, C.1
Ito, S.2
Koren, G.3
-
29
-
-
0029758869
-
Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid
-
29. Neuvonen PJ, Jalava KM (1996) Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid. Clin Pharmacol Ther 60: 54-61
-
(1996)
Clin Pharmacol Ther
, vol.60
, pp. 54-61
-
-
Neuvonen, P.J.1
Jalava, K.M.2
-
30
-
-
0031892901
-
Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole
-
30. Neuvonen PJ, Kantola T, Kivistö KT (1998) Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole. Clin Pharmacol Ther 63: 332-341
-
(1998)
Clin Pharmacol Ther
, vol.63
, pp. 332-341
-
-
Neuvonen, P.J.1
Kantola, T.2
Kivistö, K.T.3
-
31
-
-
0031670167
-
Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations
-
31. Kantola T, Kivistö KT, Neuvonen PJ (1998) Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations. Clin Pharmacol Ther 64: 177-182
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 177-182
-
-
Kantola, T.1
Kivistö, K.T.2
Neuvonen, P.J.3
-
32
-
-
0031847115
-
Effect of itraconazole on the pharmacokinetics of atorvastatin
-
32. Kantola T, Kivistö KT, Neuvonen PJ (1998) Effect of itraconazole on the pharmacokinetics of atorvastatin. Clin Pharmacol Ther 64: 58-65
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 58-65
-
-
Kantola, T.1
Kivistö, K.T.2
Neuvonen, P.J.3
-
33
-
-
0031718706
-
The interaction of diltiazem with lovastatin and pravastatin
-
33. Azie NE, Brater DC, Becker PA, Jones DR, Hall SD (1998) The interaction of diltiazem with lovastatin and pravastatin. Clin Pharmacol Ther 64: 369-377
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 369-377
-
-
Azie, N.E.1
Brater, D.C.2
Becker, P.A.3
Jones, D.R.4
Hall, S.D.5
-
35
-
-
0031957174
-
Fluconazole but not itraconazole decreases the metabolism of losartan to E-3174
-
35. Kaukonen KM, Olkkola KT, Neuvonen PJ (1998) Fluconazole but not itraconazole decreases the metabolism of losartan to E-3174. Eur J Clin Pharmacol 53: 445-449
-
(1998)
Eur J Clin Pharmacol
, vol.53
, pp. 445-449
-
-
Kaukonen, K.M.1
Olkkola, K.T.2
Neuvonen, P.J.3
-
36
-
-
0030030061
-
Reversal effect of itraconazole on adriamycin and etoposide resistance in human leukemia cells
-
36. Kurosawa M, Okabe M, Kara N, Kawamura K, Suzuki S, Sakurada K, Asaka M (1996) Reversal effect of itraconazole on adriamycin and etoposide resistance in human leukemia cells. Ann Hematol 72: 17-21
-
(1996)
Ann Hematol
, vol.72
, pp. 17-21
-
-
Kurosawa, M.1
Okabe, M.2
Kara, N.3
Kawamura, K.4
Suzuki, S.5
Sakurada, K.6
Asaka, M.7
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