Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing β-(5',6',7'-trimethoxy-2'-indolyl)acryloyl group

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 7, 2000, Pages 1637-1643

  Amishiro, Nobuyoshi ^a   Nagamura, Satoru ^a   Kobayashi, Eiji ^a   Okamoto, Akihiko ^a   Gomi, Katsushige ^a   Okabe, Masami ^a   Saito, Hiromitsu ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DUOCARMYCIN A; DUOCARMYCIN B2; PYRINDAMYCIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SYNTHESIS; HELA CELL; HUMAN CELL; INFRARED SPECTROMETRY; LEUKOCYTE COUNT; MOUSE; NONHUMAN; SARCOMA 180; THROMBOCYTE COUNT; THROMBOCYTOPENIA; XENOGRAFT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL DIVISION; HELA CELLS; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; LEUKOCYTE COUNT; MALE; MICE; NEOPLASMS, EXPERIMENTAL; PLATELET COUNT; PYRROLES; PYRROLIDINONES; TIME FACTORS; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

MURINAE;

EID: 0033920155     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00086-9     Document Type: Article

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