A convenient synthesis of disubstituted guanidines via the Mitsunobu protocol

Synlett

Volumn , Issue 2, 1999, Pages 193-194

  Kim, Hwa Ok ^a   Mathew, Felix ^a   Ogbu, Cyprian ^a  

^a Molecumetics Ltd   (United States)

Author keywords

Disubstituted guanidines; Mitsunobu reaction; Monoalkylated guanylating agents

Indexed keywords

ALCOHOL DERIVATIVE; AMINE; GUANIDINE DERIVATIVE; PYRAZOLE DERIVATIVE; THIOUREA DERIVATIVE;

ARTICLE; REACTION ANALYSIS; SYNTHESIS;

EID: 0032962814     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1999-2584     Document Type: Article

References (13)

1. a) Ogbu, C. O.; Boatman, D.; Eguchi, M.; Cao, B.; Nakanishi, H.; Kahn, M.; Tulinsky, A.; Padmanabhan, K. Abstracts of Papers, 214th National Meeting of the American Chemical Society, Las Vegas, NV; American Chemical Society: Washington, DC, September 1997; MED 60.
2. b) Peptide Secondary Structure Mimetics. Tetrahedron Symposia-in-print no. 50, Kahn, M. Ed., 1993, 49, 3444.
3. c) Kahn, M. Synlett 1993, 821.
4. d) Kim, H. -O.; Lum, C.; Lee, M. S. Tetrahedron Lett. 1997, 38, 4935.
5. e) Kim, H. -O.; Kahn, M. Tetrahedron Lett. 1997, 38, 6483.
6. a) During the preparation of this manuscript, a paper describing the solid phase synthesis of disubstituted guanidines appeared. Dodd, D. S.; Wallace, O. B. Tetrahedron Lett. 1998, 39, 5701.
7. b) Blaskovich, M.; Kahn, M. unpublished results
8. Dodd, D. S.; Kozikowski, A. P. Tetrahedron Lett. 1994, 35, 977
9. Bernatowicz, M. S.; Wu, Y.; Matsueda, G. R. Tetrahedron Lett. 1993, 21, 3389.
10. Ko, S. Y.; Lerpiniere, J.; Christofi, A. M. Synlett 1995, 815.
11. Monache, G. D.; Botta, B; Monache, F. D.; Espinal, R.; De Bonnevaux, S. C.; De Luca, C.; Botta, M.; Corelli, F.; Carmignani, M. J. Med. Chem. 1993, 36, 2956.
12. +).
13. +).