Novel histamine H3 receptor antagonists: Synthesis and evaluation of formamidine and S-methylisothiourea derivatives

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 2, 1997, Pages 305-311

  Goto, Tomokazu ^a   Sakashita, Hiroshi ^a   Murakami, Kazuki ^a   Sugiura, Masanori ^a   Kondo, Takao ^a   Fukaya, Chikara ^a  

^a Green Cross Company   (South Korea)

Author keywords

AQ0145; formamidine derivative; histamine H3 receptor antagonist; S methylisothiourea derivative

Indexed keywords

FORMAMIDINE; HISTAMINE H1 RECEPTOR; HISTAMINE H2 RECEPTOR; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; N (1 ADAMANTYL) N',N' [3 (1H IMIDAZOL 4(5) YL)PENTAMETHYLENE]FORMAMIDINE; N (1 ADAMANTYL) N',N' [3 (4(5) 1H IMIDAZOLYL)PENTAMETHYLENE]FORMAMIDINE; THIOPERAMIDE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG; AMIDINE; ANTIHISTAMINIC AGENT; DRUG DERIVATIVE; PIPERIDINE DERIVATIVE; S METHYLISOTHIOPSEUDOURONIUM; S-METHYLISOTHIOPSEUDOURONIUM;

ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; GUINEA PIG; HEART RIGHT ATRIUM; ILEUM; NONHUMAN; RAT; ANIMAL; BRAIN CORTEX; CHEMISTRY; METABOLISM; SYNTHESIS;

AMIDINES; ANIMALS; CEREBRAL CORTEX; GUINEA PIGS; HISTAMINE ANTAGONISTS; ISOTHIURONIUM; PIPERIDINES; RATS; RECEPTORS, HISTAMINE H1; RECEPTORS, HISTAMINE H2; RECEPTORS, HISTAMINE H3;

EID: 0030933889     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.305     Document Type: Article

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