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Volumn 18, Issue 6, 2000, Pages 544-554

Growth factor receptor tyrosine kinases: Cell adhesion kinase family suggests a novel signaling mechanism in cancer

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ALPHA ACTININ; CADHERIN; COLLAGEN; COLLAGENASE; DISCOIDIN; EPHRIN; FIBRONECTIN; FOCAL ADHESION KINASE; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; HLA ANTIGEN; HORMONE; IMMUNOGLOBULIN; INTEGRIN; MEMBRANE PROTEIN; MESSENGER RNA; NEUROTRANSMITTER; NEUROTROPHIN RECEPTOR; PAXILLIN; PROTEIN P53; PROTEIN S; PROTEIN TYROSINE KINASE; TALIN; VINCULIN; VITRONECTIN;

EID: 0033915130     PISSN: 07357907     EISSN: None     Source Type: Journal    
DOI: 10.3109/07357900009012194     Document Type: Review
Times cited : (25)

References (99)
  • 1
    • 0029101707 scopus 로고
    • The role of growth factor receptors in central nervous system development and neoplasia
    • Weiner HL: The role of growth factor receptors in central nervous system development and neoplasia. Neurosurgery 37:179-193, 1995.
    • (1995) Neurosurgery , vol.37 , pp. 179-193
    • Weiner, H.L.1
  • 2
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • Clark EA, Brugge JS: Integrins and signal transduction pathways: the road taken. Science 268:233-239, 1995.
    • (1995) Science , vol.268 , pp. 233-239
    • Clark, E.A.1    Brugge, J.S.2
  • 3
    • 0031310941 scopus 로고    scopus 로고
    • An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors
    • Shrivastava A, Radziejewski C, Campbell E, et al: An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors. Mol Cell 1:25-34, 1997.
    • (1997) Mol Cell , vol.1 , pp. 25-34
    • Shrivastava, A.1    Radziejewski, C.2    Campbell, E.3
  • 4
    • 0031309902 scopus 로고    scopus 로고
    • The discoidin domain receptor tyrosine kinases are activated by collagen
    • Vogel W, Gish GD, Alves F, et al: The discoidin domain receptor tyrosine kinases are activated by collagen. Mol Cell 1:13-23. 1997.
    • (1997) Mol Cell , vol.1 , pp. 13-23
    • Vogel, W.1    Gish, G.D.2    Alves, F.3
  • 5
    • 0026793456 scopus 로고
    • Growth factor signaling by receptor tyrosine kinases
    • Schlessinger J, Ullrich A: Growth factor signaling by receptor tyrosine kinases. Neuron 9:383-391, 1992.
    • (1992) Neuron , vol.9 , pp. 383-391
    • Schlessinger, J.1    Ullrich, A.2
  • 6
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • Ullrich A, Schlessinger J: Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212, 1990.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 7
    • 0026578026 scopus 로고
    • Growth factor signaling: Where is the specificity?
    • Chao MV: Growth factor signaling: where is the specificity? Cell 68:995-997, 1992.
    • (1992) Cell , vol.68 , pp. 995-997
    • Chao, M.V.1
  • 8
    • 0031470553 scopus 로고    scopus 로고
    • Direct binding and activation of receptor tyrosine kinases by collagen
    • Schlessinger J: Direct binding and activation of receptor tyrosine kinases by collagen. Cell 91:869-872, 1997.
    • (1997) Cell , vol.91 , pp. 869-872
    • Schlessinger, J.1
  • 9
    • 0023885305 scopus 로고
    • The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
    • Hanks SK, Quinn AM, Hunter T: The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 241:42-52, 1988.
    • (1988) Science , vol.241 , pp. 42-52
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 10
    • 0030485340 scopus 로고    scopus 로고
    • Pediatric brain tumors express multiple receptor tyrosine kinases including novel cell adhesion kinases
    • Weiner HL, Rothman M, Miller DC, et al: Pediatric brain tumors express multiple receptor tyrosine kinases including novel cell adhesion kinases. Pediatr Neurosurg 25:64-72, 1996.
    • (1996) Pediatr Neurosurg , vol.25 , pp. 64-72
    • Weiner, H.L.1    Rothman, M.2    Miller, D.C.3
  • 11
    • 0024788997 scopus 로고
    • The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family
    • Wilks AF, Kurban RR, Hovens CM, et al: The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family. Gene 85:67-74, 1989.
    • (1989) Gene , vol.85 , pp. 67-74
    • Wilks, A.F.1    Kurban, R.R.2    Hovens, C.M.3
  • 12
    • 0028913076 scopus 로고
    • The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases
    • Stitt TN, Conn G, Gore M. et al: The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases. Cell 80:661-670, 1995.
    • (1995) Cell , vol.80 , pp. 661-670
    • Stitt, T.N.1    Conn, G.2    Gore, M.3
  • 13
    • 0025857391 scopus 로고
    • The trk proto-oncogene encodes a receptor for nerve growth factor
    • Klein R, Jing SQ, Nanduri V, et al: The trk proto-oncogene encodes a receptor for nerve growth factor. Cell 65:189-197, 1991.
    • (1991) Cell , vol.65 , pp. 189-197
    • Klein, R.1    Jing, S.Q.2    Nanduri, V.3
  • 14
    • 0028129144 scopus 로고
    • Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors
    • Beckmann MP, Cerretti DP, Baum P, et al: Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors. EMBO J 13:3757-3762, 1994.
    • (1994) EMBO J , vol.13 , pp. 3757-3762
    • Beckmann, M.P.1    Cerretti, D.P.2    Baum, P.3
  • 15
    • 0028067458 scopus 로고
    • Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases
    • Cheng HJ, Flanagan JG: Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases. Cell 79:157-168, 1994.
    • (1994) Cell , vol.79 , pp. 157-168
    • Cheng, H.J.1    Flanagan, J.G.2
  • 16
    • 0028110068 scopus 로고
    • Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity
    • Davis S, Gale NW, Aldrich TH, et al: Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity. Science 266:816-819, 1994.
    • (1994) Science , vol.266 , pp. 816-819
    • Davis, S.1    Gale, N.W.2    Aldrich, T.H.3
  • 17
    • 0028355291 scopus 로고
    • B61 is a ligand for the ECK receptor protein-tyrosine kinase
    • Bartley TD, Hunt RW, Welcher AA, et al: B61 is a ligand for the ECK receptor protein-tyrosine kinase. Nature 368:558-560, 1994.
    • (1994) Nature , vol.368 , pp. 558-560
    • Bartley, T.D.1    Hunt, R.W.2    Welcher, A.A.3
  • 18
    • 0029851690 scopus 로고    scopus 로고
    • Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands
    • Holland SJ, Gale NW, Mbamalu G, et al: Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands. Nature 383:722-725, 1996.
    • (1996) Nature , vol.383 , pp. 722-725
    • Holland, S.J.1    Gale, N.W.2    Mbamalu, G.3
  • 19
    • 0028985212 scopus 로고
    • Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6
    • Varnum BC, Young C, Elliott G, et al: Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6. Nature 373:623-626, 1995.
    • (1995) Nature , vol.373 , pp. 623-626
    • Varnum, B.C.1    Young, C.2    Elliott, G.3
  • 20
    • 15844380040 scopus 로고    scopus 로고
    • Agrin acts via a MuSK receptor complex
    • Glass DJ, Bowen DC, Stitt TN, et al: Agrin acts via a MuSK receptor complex. Cell 85:513-523, 1996.
    • (1996) Cell , vol.85 , pp. 513-523
    • Glass, D.J.1    Bowen, D.C.2    Stitt, T.N.3
  • 21
    • 15844365303 scopus 로고    scopus 로고
    • GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF
    • Jing S, Wen D, Yu Y, et al: GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF. Cell 85:1113-1124, 1996.
    • (1996) Cell , vol.85 , pp. 1113-1124
    • Jing, S.1    Wen, D.2    Yu, Y.3
  • 22
    • 15844418441 scopus 로고    scopus 로고
    • Characterization of multicomponent receptor for GDNF
    • Treanor JJ, Goodman L, de SF, et al: Characterization of multicomponent receptor for GDNF [see comments] Nature 382:80-83, 1996.
    • (1996) Nature , vol.382 , pp. 80-83
    • Treanor, J.J.1    Goodman, L.2    De, S.F.3
  • 23
    • 0030460424 scopus 로고    scopus 로고
    • Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
    • Davis S, Aldrich TH, Jones PF, et al: Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning [see comments] Cell 87:1161-1169, 1996.
    • (1996) Cell , vol.87 , pp. 1161-1169
    • Davis, S.1    Aldrich, T.H.2    Jones, P.F.3
  • 24
    • 15144358851 scopus 로고    scopus 로고
    • Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
    • Maisonpierre PC, Suri C, Jones PF, et al: Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis [see comments] Science 277:55-60, 1997.
    • (1997) Science , vol.277 , pp. 55-60
    • Maisonpierre, P.C.1    Suri, C.2    Jones, P.F.3
  • 25
    • 0026730310 scopus 로고
    • Neurotrophin receptors: A window into neuronal differentiation
    • Chao MV: Neurotrophin receptors: a window into neuronal differentiation. Neuron 9:583-593, 1992.
    • (1992) Neuron , vol.9 , pp. 583-593
    • Chao, M.V.1
  • 26
    • 0025805606 scopus 로고
    • An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system
    • Lai C, Lemke G: An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system. Neuron 6:691-704, 1991.
    • (1991) Neuron , vol.6 , pp. 691-704
    • Lai, C.1    Lemke, G.2
  • 27
    • 0028325796 scopus 로고
    • Multiple tyrosine protein kinases in rat hippocampal neurons: Isolation of Ptk-3, a receptor expressed in proliferative zones of the developing brain
    • Sanchez MP, Tapley P, Saini SS, et al: Multiple tyrosine protein kinases in rat hippocampal neurons: isolation of Ptk-3, a receptor expressed in proliferative zones of the developing brain. Proc Natl Acad Sci USA 91:1819-1823, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1819-1823
    • Sanchez, M.P.1    Tapley, P.2    Saini, S.S.3
  • 28
    • 0027287428 scopus 로고
    • Molecular cloning of the murine JAKI protein tyrosine kinase and its expression in the mouse central nervous system
    • Yang X, Chung D, Cepko CL: Molecular cloning of the murine JAKI protein tyrosine kinase and its expression in the mouse central nervous system. J Neurosci 13:3006-3017, 1993.
    • (1993) J Neurosci , vol.13 , pp. 3006-3017
    • Yang, X.1    Chung, D.2    Cepko, C.L.3
  • 29
    • 0026025755 scopus 로고
    • Growth factors in development, transformation, and tumorigenesis
    • Cross M, Dexter TM: Growth factors in development, transformation, and tumorigenesis. Cell 64:271-280, 1991.
    • (1991) Cell , vol.64 , pp. 271-280
    • Cross, M.1    Dexter, T.M.2
  • 30
    • 0027461752 scopus 로고
    • Cloning and growth of multipotential neural precursors: Requirements for proliferation and differentiation
    • Kilpatrick TJ, Bartlett PF: Cloning and growth of multipotential neural precursors: requirements for proliferation and differentiation. Neuron 10:255-265, 1993.
    • (1993) Neuron , vol.10 , pp. 255-265
    • Kilpatrick, T.J.1    Bartlett, P.F.2
  • 31
    • 0026015023 scopus 로고
    • Signal transduction and the fate of the R7 photoreceptor in Drosophila
    • Rubin GM: Signal transduction and the fate of the R7 photoreceptor in Drosophila. Trends Genet 7:372-377, 1991.
    • (1991) Trends Genet , vol.7 , pp. 372-377
    • Rubin, G.M.1
  • 32
    • 0027317743 scopus 로고
    • Five novel avian Eph-related tyrosine kinases are differentially expressed
    • Sajjadi FG, Pasquale EB: Five novel avian Eph-related tyrosine kinases are differentially expressed. Oncogene 8:1807-1813, 1993.
    • (1993) Oncogene , vol.8 , pp. 1807-1813
    • Sajjadi, F.G.1    Pasquale, E.B.2
  • 33
    • 0027955017 scopus 로고
    • Identification and chromosomal mapping of a receptor tyrosine kinase with a putative phospholipid binding sequence in its ectodomain
    • Perez JL, Shen X, Finkernagel S, et al: Identification and chromosomal mapping of a receptor tyrosine kinase with a putative phospholipid binding sequence in its ectodomain. Oncogene 9:211-219, 1994.
    • (1994) Oncogene , vol.9 , pp. 211-219
    • Perez, J.L.1    Shen, X.2    Finkernagel, S.3
  • 34
    • 0029987919 scopus 로고    scopus 로고
    • Identification of two isoforms of the Cak receptor kinase that are coexpressed in breast tumor cell lines
    • Perez JL, Jing SQ, Wong TW: Identification of two isoforms of the Cak receptor kinase that are coexpressed in breast tumor cell lines. Oncogene 12:1469-1477, 1996.
    • (1996) Oncogene , vol.12 , pp. 1469-1477
    • Perez, J.L.1    Jing, S.Q.2    Wong, T.W.3
  • 35
    • 0027955470 scopus 로고
    • Structure and expression of the Tyro 10 receptor tyrosine kinase
    • Lai C, Lemke G: Structure and expression of the Tyro 10 receptor tyrosine kinase. Oncogene 9:877-883, 1994.
    • (1994) Oncogene , vol.9 , pp. 877-883
    • Lai, C.1    Lemke, G.2
  • 36
    • 0027304064 scopus 로고
    • NEP: A novel receptor-like tyrosine kinase expressed in proliferating neuroepithelia
    • Zerlin M, Julius MA, Goldfarb M: NEP: a novel receptor-like tyrosine kinase expressed in proliferating neuroepithelia. Oncogene 8:2731-2739, 1993.
    • (1993) Oncogene , vol.8 , pp. 2731-2739
    • Zerlin, M.1    Julius, M.A.2    Goldfarb, M.3
  • 37
    • 0028271497 scopus 로고
    • Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors
    • Resnicoff M, Sell C, Rubini M, et al: Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors. Cancer Res 54:2218-2222, 1994.
    • (1994) Cancer Res , vol.54 , pp. 2218-2222
    • Resnicoff, M.1    Sell, C.2    Rubini, M.3
  • 38
    • 0026526516 scopus 로고
    • A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes
    • Reynolds BA, Tetzlaff W, Weiss S: A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. J Neurosci 12:4565-4574, 1992.
    • (1992) J Neurosci , vol.12 , pp. 4565-4574
    • Reynolds, B.A.1    Tetzlaff, W.2    Weiss, S.3
  • 39
    • 0027491410 scopus 로고
    • bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells
    • Vescovi AL, Reynolds BA, Fraser DD, et al: bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells. Neuron 11:951-966, 1993.
    • (1993) Neuron , vol.11 , pp. 951-966
    • Vescovi, A.L.1    Reynolds, B.A.2    Fraser, D.D.3
  • 40
    • 0023182049 scopus 로고
    • A common progenitor for neurons and glia persists in rat retina late in development
    • Turner DL, Cepko CL: A common progenitor for neurons and glia persists in rat retina late in development. Nature 328:131-136, 1987.
    • (1987) Nature , vol.328 , pp. 131-136
    • Turner, D.L.1    Cepko, C.L.2
  • 41
    • 0024509580 scopus 로고
    • Glial cell diversification in the rat optic nerve
    • Raff MC: Glial cell diversification in the rat optic nerve. Science 243:1450-1455, 1989.
    • (1989) Science , vol.243 , pp. 1450-1455
    • Raff, M.C.1
  • 42
    • 0027437634 scopus 로고
    • Molecular cloning of trkE, a novel trk-related putative tyrosine kinase receptor isolated from normal human keratinocytes and widely expressed by normal human tissues
    • Di Marco E, Cutuli N, Guerra L, et al: Molecular cloning of trkE, a novel trk-related putative tyrosine kinase receptor isolated from normal human keratinocytes and widely expressed by normal human tissues. J Biol Chem 268:24290-24295, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 24290-24295
    • Di Marco, E.1    Cutuli, N.2    Guerra, L.3
  • 43
    • 0022641294 scopus 로고
    • A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences
    • Martin ZD, Hughes SH, Barbacid M: A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences. Nature 319:743-748, 1986.
    • (1986) Nature , vol.319 , pp. 743-748
    • Martin, Z.D.1    Hughes, S.H.2    Barbacid, M.3
  • 44
    • 0023663896 scopus 로고
    • Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells
    • Di Fiore P, Pierce JH, Fleming TP, et al: Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells. Cell 51:1063-1070, 1987.
    • (1987) Cell , vol.51 , pp. 1063-1070
    • Di Fiore, P.1    Pierce, J.H.2    Fleming, T.P.3
  • 45
    • 0020533055 scopus 로고
    • Simian sarcoma virus one gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor
    • Doolittle RF, Hunkapiller MW, Hood LE, et al: Simian sarcoma virus one gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor. Science 221:275-277, 1983.
    • (1983) Science , vol.221 , pp. 275-277
    • Doolittle, R.F.1    Hunkapiller, M.W.2    Hood, L.E.3
  • 46
    • 0021281324 scopus 로고
    • Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
    • Downward J, Yarden Y, Mayes E, et al: Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences. Nature 307:521-527, 1984.
    • (1984) Nature , vol.307 , pp. 521-527
    • Downward, J.1    Yarden, Y.2    Mayes, E.3
  • 47
    • 0028332782 scopus 로고
    • Fibroblast growth factor receptor gene expression and immunoreactivity are elevated in human glioblastoma multiforme
    • Morrison RS, Yamaguchi F, Bruner JM, et al: Fibroblast growth factor receptor gene expression and immunoreactivity are elevated in human glioblastoma multiforme. Cancer Res 54:2794-2799, 1994.
    • (1994) Cancer Res , vol.54 , pp. 2794-2799
    • Morrison, R.S.1    Yamaguchi, F.2    Bruner, J.M.3
  • 48
    • 0025201337 scopus 로고
    • Immunohistochemical localization of basic fibroblast growth factor in astrocytomas
    • Zagzag D, Miller DC, Sato Y, et al: Immunohistochemical localization of basic fibroblast growth factor in astrocytomas. Cancer Res 50:7393-7398, 1990.
    • (1990) Cancer Res , vol.50 , pp. 7393-7398
    • Zagzag, D.1    Miller, D.C.2    Sato, Y.3
  • 49
    • 0023429079 scopus 로고
    • Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification
    • Wong AJ, Bigner SH, Bigner DD, et al: Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. Proc Nat Acad Sci USA 84:6899-6903, 1987.
    • (1987) Proc Nat Acad Sci USA , vol.84 , pp. 6899-6903
    • Wong, A.J.1    Bigner, S.H.2    Bigner, D.D.3
  • 50
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
    • Plate KH, Breier G, Weich HA, et al: Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359:845-848, 1992.
    • (1992) Nature , vol.359 , pp. 845-848
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3
  • 51
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
    • Millauer B, Shawver LK, Plate KH, et al: Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 367:576-579, 1994.
    • (1994) Nature , vol.367 , pp. 576-579
    • Millauer, B.1    Shawver, L.K.2    Plate, K.H.3
  • 52
    • 0026772431 scopus 로고
    • Platelet-derived growth factor and its receptors in human glioma tissue: Expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops
    • Hermanson M, Funa K, Hartman M, et al: Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. Cancer Res 52:3213-3219, 1992.
    • (1992) Cancer Res , vol.52 , pp. 3213-3219
    • Hermanson, M.1    Funa, K.2    Hartman, M.3
  • 53
    • 0024379685 scopus 로고
    • Insulin and insulin-like growth factor I in brain tumors: Binding and in vitro effects
    • Glick RP, Gettleman R, Patel K, et al: Insulin and insulin-like growth factor I in brain tumors: binding and in vitro effects. Neurosurgery 24:791-797, 1989.
    • (1989) Neurosurgery , vol.24 , pp. 791-797
    • Glick, R.P.1    Gettleman, R.2    Patel, K.3
  • 54
    • 0021932240 scopus 로고
    • Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
    • Libermann TA, Nusbaum HR, Razon N, et al: Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature 313: 144-147, 1985.
    • (1985) Nature , vol.313 , pp. 144-147
    • Libermann, T.A.1    Nusbaum, H.R.2    Razon, N.3
  • 55
    • 0025790916 scopus 로고
    • Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo
    • Ekstrand AJ, James CD, Cavenee WK, et al: Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res 51:2164-2172, 1991.
    • (1991) Cancer Res , vol.51 , pp. 2164-2172
    • Ekstrand, A.J.1    James, C.D.2    Cavenee, W.K.3
  • 56
    • 0026793260 scopus 로고
    • Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors
    • Fleming TP, Saxena A, Clark WC, et al: Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors. Cancer Res 52:4550-4553, 1992.
    • (1992) Cancer Res , vol.52 , pp. 4550-4553
    • Fleming, T.P.1    Saxena, A.2    Clark, W.C.3
  • 57
    • 0025214980 scopus 로고
    • Basic fibroblast growth factor-like activity and receptors are expressed in a human glioma cell line
    • published erratum appears in Cancer Res 1990 Aug 1; 50(15):4825
    • Morrison RS, Gross JL, Herblin WF, et al: Basic fibroblast growth factor-like activity and receptors are expressed in a human glioma cell line [published erratum appears in Cancer Res 1990 Aug 1; 50(15):4825] Cancer Res 50:2524-2529, 1990.
    • (1990) Cancer Res , vol.50 , pp. 2524-2529
    • Morrison, R.S.1    Gross, J.L.2    Herblin, W.F.3
  • 58
    • 0027157692 scopus 로고
    • A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain
    • Johnson JD, Edman JC, Rutter WJ: A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain. Proc Natl Acad Sci USA 90:5677-5681, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5677-5681
    • Johnson, J.D.1    Edman, J.C.2    Rutter, W.J.3
  • 59
    • 0027442939 scopus 로고
    • Structure, expression and chromosomal mapping of TKT from man and mouse: A new subclass of receptor tyrosine kinases with a factor VIII- like domain
    • Karn T. Holtrich U, Brauninger A, et al: Structure, expression and chromosomal mapping of TKT from man and mouse: a new subclass of receptor tyrosine kinases with a factor VIII- like domain. Oncogene 8:3433-3440, 1993.
    • (1993) Oncogene , vol.8 , pp. 3433-3440
    • Karn, T.1    Holtrich, U.2    Brauninger, A.3
  • 60
    • 0028799694 scopus 로고
    • Distinct structural characteristics of discoidin I subfamily receptor tyrosine kinases and complementary expression in human cancer
    • Alves F, Vogel W, Mossie K, et al: Distinct structural characteristics of discoidin I subfamily receptor tyrosine kinases and complementary expression in human cancer. Oncogene 10:609-618, 1995.
    • (1995) Oncogene , vol.10 , pp. 609-618
    • Alves, F.1    Vogel, W.2    Mossie, K.3
  • 61
    • 0028954535 scopus 로고
    • Mapping of the NEP receptor tyrosine kinase gene to human chromosome 6p21.3 and mouse chromosome 17C
    • Edelhoff S, Sweetser DA, Disteche CM: Mapping of the NEP receptor tyrosine kinase gene to human chromosome 6p21.3 and mouse chromosome 17C. Genomics 25:309-311, 1995.
    • (1995) Genomics , vol.25 , pp. 309-311
    • Edelhoff, S.1    Sweetser, D.A.2    Disteche, C.M.3
  • 62
    • 0029792637 scopus 로고    scopus 로고
    • The genomic structure of discoidin receptor tyrosine kinase
    • Playford MP, Butler RJ, Wang XC, et al: The genomic structure of discoidin receptor tyrosine kinase. Genome Res 6:620-627, 1996.
    • (1996) Genome Res , vol.6 , pp. 620-627
    • Playford, M.P.1    Butler, R.J.2    Wang, X.C.3
  • 63
    • 0030566840 scopus 로고    scopus 로고
    • Receptor protein tyrosine kinase DDR is up-regulated by p53 protein
    • Sakuma S, Saya H, Tada M, et al: Receptor protein tyrosine kinase DDR is up-regulated by p53 protein. FEBS Lett 398:165-169, 1996.
    • (1996) FEBS Lett , vol.398 , pp. 165-169
    • Sakuma, S.1    Saya, H.2    Tada, M.3
  • 64
    • 0029032929 scopus 로고
    • Radiation induction of the receptor tyrosine kinase gene Ptk-3 in normal rat astrocytes
    • Sakuma S, Saya H, Ijichi A, et al: Radiation induction of the receptor tyrosine kinase gene Ptk-3 in normal rat astrocytes. Radiat Res 143:1-7, 1995.
    • (1995) Radiat Res , vol.143 , pp. 1-7
    • Sakuma, S.1    Saya, H.2    Ijichi, A.3
  • 65
    • 0028832062 scopus 로고
    • Expression patterns of the novel receptor-like tyrosine kinase, DDR, in human breast tumours
    • Barker KT, Martindale JE, Mitchell PJ, et al: Expression patterns of the novel receptor-like tyrosine kinase, DDR, in human breast tumours. Oncogene 10:569-575, 1995.
    • (1995) Oncogene , vol.10 , pp. 569-575
    • Barker, K.T.1    Martindale, J.E.2    Mitchell, P.J.3
  • 66
    • 0030787169 scopus 로고    scopus 로고
    • Overexpression of protein tyrosine kinases in human esophageal cancer
    • Nemoto T, Ohashi K, Akashi T, et al: Overexpression of protein tyrosine kinases in human esophageal cancer. Pathobiology 65: 195-203, 1997.
    • (1997) Pathobiology , vol.65 , pp. 195-203
    • Nemoto, T.1    Ohashi, K.2    Akashi, T.3
  • 67
    • 0026770377 scopus 로고
    • Integrins: Versitality, modulation and signaling in cell adhesion
    • Hynes RO: Integrins: versitality, modulation and signaling in cell adhesion. Cell 69:11-25, 1992.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 68
    • 0028817908 scopus 로고
    • Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex
    • Plopper G, McNamee H, Dike L, et al: Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex. Mol Biol Cell 6:1349-1365, 1995.
    • (1995) Mol Biol Cell , vol.6 , pp. 1349-1365
    • Plopper, G.1    McNamee, H.2    Dike, L.3
  • 69
    • 0026445719 scopus 로고
    • Tyrosine phosphorylation of pazillin and 125FAK acompanies cell adhesion to extracellular matrix: A role in cytoskelelal assembly
    • Burridge K, Turner CE, Romer LH: Tyrosine phosphorylation of pazillin and 125FAK acompanies cell adhesion to extracellular matrix: a role in cytoskelelal assembly. J Cell Biol 119:893-903, 1992.
    • (1992) J Cell Biol , vol.119 , pp. 893-903
    • Burridge, K.1    Turner, C.E.2    Romer, L.H.3
  • 70
    • 0031003706 scopus 로고
    • The role of conserved amino acid motifs within the integrin beta-3 cytoplasmic domain in triggering focal adhesion kinase phosphorylation
    • Tahiliani PD, Singh L, Auer KL, et al: The role of conserved amino acid motifs within the integrin beta-3 cytoplasmic domain in triggering focal adhesion kinase phosphorylation. J Biol Chem 272:7892-7898, 1995.
    • (1995) J Biol Chem , vol.272 , pp. 7892-7898
    • Tahiliani, P.D.1    Singh, L.2    Auer, K.L.3
  • 71
    • 0029971297 scopus 로고    scopus 로고
    • A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125 FAK
    • Richardson A, Parsons JT: A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125 FAK. Nature 380:538-540, 1996.
    • (1996) Nature , vol.380 , pp. 538-540
    • Richardson, A.1    Parsons, J.T.2
  • 72
    • 0029034873 scopus 로고
    • Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, an Src homology 3-containing molecule having multiple Src homology 2-binding motifs
    • Nojima Y, Morino N, Mimura T, et al: Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, an Src homology 3-containing molecule having multiple Src homology 2-binding motifs. J Biol Chem 270:15398-15402, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 15398-15402
    • Nojima, Y.1    Morino, N.2    Mimura, T.3
  • 73
    • 0029664531 scopus 로고    scopus 로고
    • Induction of p130Cas signaling complex formation upon integrin-mediated cell adhesion: A role for Src family kinases
    • Vuori K, Hirai H, Aizawa S, et al: Induction of p130Cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases. Mol Cell Biol 16:2606-2613, 1996.
    • (1996) Mol Cell Biol , vol.16 , pp. 2606-2613
    • Vuori, K.1    Hirai, H.2    Aizawa, S.3
  • 74
    • 0028889436 scopus 로고    scopus 로고
    • Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas
    • Polte TR, Hanks SK: Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas. Proc Natl Acad Sci USA 92:10678-10682, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.92 , pp. 10678-10682
    • Polte, T.R.1    Hanks, S.K.2
  • 75
    • 0029120440 scopus 로고
    • Reduced cell motilily and enhanced focal adhesion contact formation in cell from FAK-deficient mice
    • Ilic D, Furuta Y, Kanazawa S, et al: Reduced cell motilily and enhanced focal adhesion contact formation in cell from FAK-deficient mice. Nature 377:539-544, 1995.
    • (1995) Nature , vol.377 , pp. 539-544
    • Ilic, D.1    Furuta, Y.2    Kanazawa, S.3
  • 76
    • 0029741102 scopus 로고    scopus 로고
    • Inhibition of focal adhesion kinase (FAK) signaling focal adhesions decreases cell motility and proliferation
    • Gilmore AP, Romer LH: Inhibition of focal adhesion kinase (FAK) signaling focal adhesions decreases cell motility and proliferation. Mol Biol Cell 7:1209-1224, 1996.
    • (1996) Mol Biol Cell , vol.7 , pp. 1209-1224
    • Gilmore, A.P.1    Romer, L.H.2
  • 77
    • 0029039421 scopus 로고
    • Overexpression of focal adhesion kinase (pp125FAK) in invasive human tumors
    • Owens LV, Xu L, Craven RJ, et al: Overexpression of focal adhesion kinase (pp125FAK) in invasive human tumors. Cancer Res 55:2752-2755, 1995.
    • (1995) Cancer Res , vol.55 , pp. 2752-2755
    • Owens, L.V.1    Xu, L.2    Craven, R.J.3
  • 78
    • 0028122650 scopus 로고
    • Focal adhesion kinase and associated proteins
    • Schaller M, Parsons T: Focal adhesion kinase and associated proteins. Curr Opin Cell Biol 6:705-710, 1994.
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 705-710
    • Schaller, M.1    Parsons, T.2
  • 79
    • 0029087478 scopus 로고
    • Modulation of cell spreading and migration by pp125 FAK phosphorylation
    • Sankar S, Mahooti-Brooks N, Hu G, et al: Modulation of cell spreading and migration by pp125 FAK phosphorylation. Am J Pathol 147:601-608, 1995.
    • (1995) Am J Pathol , vol.147 , pp. 601-608
    • Sankar, S.1    Mahooti-Brooks, N.2    Hu, G.3
  • 80
    • 0029929675 scopus 로고    scopus 로고
    • Migration of brain tumor cells on extracellular matrix proteins in vitro correlates with tumor type and grade, and involve alpha-v and beta-1 integrins
    • Friedlander D, Zagzag D, Shiff B, et al: Migration of brain tumor cells on extracellular matrix proteins in vitro correlates with tumor type and grade, and involve alpha-v and beta-1 integrins. Cancer Res 56:1939-1947, 1996.
    • (1996) Cancer Res , vol.56 , pp. 1939-1947
    • Friedlander, D.1    Zagzag, D.2    Shiff, B.3
  • 81
    • 0030465547 scopus 로고    scopus 로고
    • Diffuse brain invasion of glioma cells requires beta-1 integrins
    • Paulus W, Baur I, Beuller AS, et al: Diffuse brain invasion of glioma cells requires beta-1 integrins. Lab Invest 75:819-826, 1996.
    • (1996) Lab Invest , vol.75 , pp. 819-826
    • Paulus, W.1    Baur, I.2    Beuller, A.S.3
  • 82
    • 0033118450 scopus 로고    scopus 로고
    • Prostatic carcinoma cell migration via alpha-v-beta-3 integrin is modulated by it focal adhesion kinase pathway
    • Zheng DQ, Woodard AS, Fornaro M, et al: Prostatic carcinoma cell migration via alpha-v-beta-3 integrin is modulated by it focal adhesion kinase pathway. Cancer Res 59:1655-1664, 1999.
    • (1999) Cancer Res , vol.59 , pp. 1655-1664
    • Zheng, D.Q.1    Woodard, A.S.2    Fornaro, M.3
  • 83
    • 0029848157 scopus 로고    scopus 로고
    • Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells
    • Xu LH, Owens LV, Sturge GC, et al: Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells. Cell Growth Diff 7:413-418, 1996.
    • (1996) Cell Growth Diff , vol.7 , pp. 413-418
    • Xu, L.H.1    Owens, L.V.2    Sturge, G.C.3
  • 84
    • 0029739950 scopus 로고    scopus 로고
    • Control of adhesion dependent cell survival by focal adhesion kinase
    • Frisch SM, Vouri K, Ruoslahti E, et al: Control of adhesion dependent cell survival by focal adhesion kinase. J Cell Biol 134: 793-799, 1996.
    • (1996) J Cell Biol , vol.134 , pp. 793-799
    • Frisch, S.M.1    Vouri, K.2    Ruoslahti, E.3
  • 87
    • 0028331263 scopus 로고
    • Tyrosine kinase cativity, cytoskeletal organization, and motility in human vascular endothelial cells
    • Romer LH, McLean N, Turner CE, et al: Tyrosine kinase cativity, cytoskeletal organization, and motility in human vascular endothelial cells. Mol Biol Cell 5:349-361, 1994.
    • (1994) Mol Biol Cell , vol.5 , pp. 349-361
    • Romer, L.H.1    McLean, N.2    Turner, C.E.3
  • 88
    • 0029795243 scopus 로고    scopus 로고
    • Focal adhesion kinase pp125FAK expression, activation and association with paxillian and p50CSK in human metastatic prostate carcinoma
    • Tremblay L, Hauck W, Aprikian AG, et al: Focal adhesion kinase pp125FAK expression, activation and association with paxillian and p50CSK in human metastatic prostate carcinoma. Int J Cancer 68:164-171, 1996.
    • (1996) Int J Cancer , vol.68 , pp. 164-171
    • Tremblay, L.1    Hauck, W.2    Aprikian, A.G.3
  • 89
    • 0029050683 scopus 로고
    • Requirement of the NPXY motif in the integrin beta-3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo
    • Filardo EJ, Brooks PC, Deming SI, et al: Requirement of the NPXY motif in the integrin beta-3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo. J Cell Biol 130:1-10, 1995.
    • (1995) J Cell Biol , vol.130 , pp. 1-10
    • Filardo, E.J.1    Brooks, P.C.2    Deming, S.I.3
  • 90
    • 0029051006 scopus 로고
    • Expression and function of beta-1 and alpha-v-beta-3 integrins in ovarian cancer
    • Cannistra SA, Ottensmeier C, Niloff J, et al: Expression and function of beta-1 and alpha-v-beta-3 integrins in ovarian cancer. Gynecol Oncol 58:216-225, 1995.
    • (1995) Gynecol Oncol , vol.58 , pp. 216-225
    • Cannistra, S.A.1    Ottensmeier, C.2    Niloff, J.3
  • 91
    • 0029937529 scopus 로고    scopus 로고
    • Integrin alph-v-beta-3 expression by bone-residing breast cancer metastases
    • Liapis H, Flath A, Kitazawa S: Integrin alph-v-beta-3 expression by bone-residing breast cancer metastases Diagn Mol Pathol 5: 127-135, 1996.
    • (1996) Diagn Mol Pathol , vol.5 , pp. 127-135
    • Liapis, H.1    Flath, A.2    Kitazawa, S.3
  • 92
    • 0025012050 scopus 로고
    • Integrin distribution in malignant melanoma: Association of the beta-3 subunit with tumor progression
    • Albelda SM, Mette SA, Elder DE, et al: Integrin distribution in malignant melanoma: association of the beta-3 subunit with tumor progression. Cancer Res 50:6757-6764, 1990.
    • (1990) Cancer Res , vol.50 , pp. 6757-6764
    • Albelda, S.M.1    Mette, S.A.2    Elder, D.E.3
  • 93
    • 0026542056 scopus 로고
    • Integrin expression in human melanoma cells with differing invasive and metastatic properties
    • Gehlsen KR, Davis GE, Sriramarao P: Integrin expression in human melanoma cells with differing invasive and metastatic properties. Clin Exp Metast 10:111-120, 1992.
    • (1992) Clin Exp Metast , vol.10 , pp. 111-120
    • Gehlsen, K.R.1    Davis, G.E.2    Sriramarao, P.3
  • 94
    • 85037957093 scopus 로고    scopus 로고
    • Molecular events implicated in brain tumor angiogenesis and invasion
    • in press
    • Zagzag D, Friedlander DR, Grumet M, et al: Molecular events implicated in brain tumor angiogenesis and invasion. Pediatr Neurosurg (in press).
    • Pediatr Neurosurg
    • Zagzag, D.1    Friedlander, D.R.2    Grumet, M.3
  • 95
    • 0031309902 scopus 로고    scopus 로고
    • The discoidin domain receptor tyrosine kinases are activated by collagen
    • Vogel W, Gish GD, Alves F, et al: The discoidin domain receptor tyrosine kinases are activated by collagen. Mol Cell 1:13-23, 1997.
    • (1997) Mol Cell , vol.1 , pp. 13-23
    • Vogel, W.1    Gish, G.D.2    Alves, F.3
  • 96
    • 0032907677 scopus 로고    scopus 로고
    • Angiotensin II signal transduction in vascular smooth muscle: Pathways activated by specific tyrosine kinases
    • Berk BC: Angiotensin II signal transduction in vascular smooth muscle: pathways activated by specific tyrosine kinases. J Am Soc Nephrol 11:62-68, 1999.
    • (1999) J Am Soc Nephrol , vol.11 , pp. 62-68
    • Berk, B.C.1
  • 97
    • 0032583122 scopus 로고    scopus 로고
    • Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways
    • Gu J, Tamura M, Yamada KM, et al: Tumor suppressor PTEN inhibits integrin-and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways. J Cell Biol 143:1375-1383, 1998.
    • (1998) J Cell Biol , vol.143 , pp. 1375-1383
    • Gu, J.1    Tamura, M.2    Yamada, K.M.3
  • 98
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • Tamura M, Gu J, Matsumoto K, et al: Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 280:1614-1617, 1998.
    • (1998) Science , vol.280 , pp. 1614-1617
    • Tamura, M.1    Gu, J.2    Matsumoto, K.3
  • 99
    • 0029995767 scopus 로고    scopus 로고
    • Glioma invasion in the central nervous system
    • Giese A, Westphal M: Glioma invasion in the central nervous system. Neurosurgery 39:235-250, 1996.
    • (1996) Neurosurgery , vol.39 , pp. 235-250
    • Giese, A.1    Westphal, M.2


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