메뉴 건너뛰기




Volumn 14, Issue 3 B, 2000, Pages 464-472

In glaucoma, should enthusiasm about neuroprotection be tempered by the experience obtained in other neurodegenerative disorders?

Author keywords

Glaucoma pharmacology; Glaucomatous excavation; Intraocular pressure; Normal tension glaucoma; Optic nerve head; Visual field defects

Indexed keywords

CASPASE; CYTOCHROME C; EXCITOTOXIN; GLUTAMIC ACID; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

EID: 0033911287     PISSN: 0950222X     EISSN: None     Source Type: Journal    
DOI: 10.1038/eye.2000.132     Document Type: Article
Times cited : (15)

References (90)
  • 1
    • 0019523221 scopus 로고
    • Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage
    • Quigley HA, Addicks EM, Green WR, Maumenee AE. Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage. Arch Ophthalmol 1981;99:635-49.
    • (1981) Arch Ophthalmol , vol.99 , pp. 635-649
    • Quigley, H.A.1    Addicks, E.M.2    Green, W.R.3    Maumenee, A.E.4
  • 2
    • 0018632223 scopus 로고
    • The histology of human glaucoma cupping and optic nerve damage: Clinicopathologic correlation in 21 eyes
    • Quigley HA, Green WR. The histology of human glaucoma cupping and optic nerve damage: clinicopathologic correlation in 21 eyes. Ophthalmology 1979;86:1803-30.
    • (1979) Ophthalmology , vol.86 , pp. 1803-1830
    • Quigley, H.A.1    Green, W.R.2
  • 4
    • 0029129202 scopus 로고
    • Comparison of ganglion cell loss and cone loss in experimental glaucoma
    • Wygnanski T, Desatnik H, Quigley HA, Glovinsky Y. Comparison of ganglion cell loss and cone loss in experimental glaucoma. Am J Ophthalmol 1995;120:184-9.
    • (1995) Am J Ophthalmol , vol.120 , pp. 184-189
    • Wygnanski, T.1    Desatnik, H.2    Quigley, H.A.3    Glovinsky, Y.4
  • 5
    • 0017066793 scopus 로고
    • Glaucomatous cupping of the human optic disk: A neurohistologic study
    • Vrabec F. Glaucomatous cupping of the human optic disk: a neurohistologic study. Graefes Arch Clin Exp Ophthalmol 1976;198:223-34.
    • (1976) Graefes Arch Clin Exp Ophthalmol , vol.198 , pp. 223-234
    • Vrabec, F.1
  • 6
    • 0017939256 scopus 로고
    • The disc and the field in glaucoma
    • Drance SM. The disc and the field in glaucoma. Ophthalmology 1978;85:209-14.
    • (1978) Ophthalmology , vol.85 , pp. 209-214
    • Drance, S.M.1
  • 7
    • 0027475589 scopus 로고
    • Progression of disc and field damage in early glaucoma
    • Zeyen TG, Caprioli J. Progression of disc and field damage in early glaucoma. Arch Ophthalmol 1993;111:62-5.
    • (1993) Arch Ophthalmol , vol.111 , pp. 62-65
    • Zeyen, T.G.1    Caprioli, J.2
  • 8
    • 0020042426 scopus 로고
    • Optic nerve damage in human glaucoma. III. Quantitative correlation of nerve fiber loss and visual field defect in glaucoma, ischemic neuropathy, papilledema, and toxic neuropathy
    • Quigley HA, Addicks E, Green WR. Optic nerve damage in human glaucoma. III. Quantitative correlation of nerve fiber loss and visual field defect in glaucoma, ischemic neuropathy, papilledema, and toxic neuropathy. Arch Ophthalmol 1982;100:135-46.
    • (1982) Arch Ophthalmol , vol.100 , pp. 135-146
    • Quigley, H.A.1    Addicks, E.2    Green, W.R.3
  • 9
    • 0024402107 scopus 로고
    • Retinal ganglion cell atrophy correlated with automated perimetry in human eyes with glaucoma
    • Quigley HA, Dunkelberger GR, Green WR. Retinal ganglion cell atrophy correlated with automated perimetry in human eyes with glaucoma. Am J Ophthalmol 1989;107:453-64.
    • (1989) Am J Ophthalmol , vol.107 , pp. 453-464
    • Quigley, H.A.1    Dunkelberger, G.R.2    Green, W.R.3
  • 11
    • 0000898764 scopus 로고
    • Hemorrhage of the optic disc and neurosensorial dysacousia
    • Susanna R, Bassetto FL. Hemorrhage of the optic disc and neurosensorial dysacousia. J Glaucoma 1992;1:248-53.
    • (1992) J Glaucoma , vol.1 , pp. 248-253
    • Susanna, R.1    Bassetto, F.L.2
  • 13
    • 0030737499 scopus 로고    scopus 로고
    • The logic of prevention of glaucomatous damage progression
    • Haefliger IO, Flammer J. The logic of prevention of glaucomatous damage progression. Curr Opin Ophthalmol 1997;8:64-7.
    • (1997) Curr Opin Ophthalmol , vol.8 , pp. 64-67
    • Haefliger, I.O.1    Flammer, J.2
  • 15
    • 0032799037 scopus 로고    scopus 로고
    • Ganglion cell death in glaucoma: What do we really know?
    • Osborne NN, Melena J, Nash M. Ganglion cell death in glaucoma: what do we really know? Br J Ophthalmol 1999;83:980-6.
    • (1999) Br J Ophthalmol , vol.83 , pp. 980-986
    • Osborne, N.N.1    Melena, J.2    Nash, M.3
  • 16
    • 0029908754 scopus 로고    scopus 로고
    • Retinal ganglion cell death in glaucoma: The how, the why, and the maybe
    • Nickells RW. Retinal ganglion cell death in glaucoma: the how, the why, and the maybe. J Glaucoma 1996;5:345-56.
    • (1996) J Glaucoma , vol.5 , pp. 345-356
    • Nickells, R.W.1
  • 17
    • 0032797074 scopus 로고    scopus 로고
    • Apoptosis of retinal ganglion cells in glaucoma: An update of the molecular pathways involved in cell death
    • Nickells RW. Apoptosis of retinal ganglion cells in glaucoma: an update of the molecular pathways involved in cell death. Surv Ophthalmol 1999;43:S151-61.
    • (1999) Surv Ophthalmol , vol.43
    • Nickells, R.W.1
  • 18
    • 0032776942 scopus 로고    scopus 로고
    • An experimental basis for implicating excitotoxicity in glaucomatous optic neuropathy
    • Vorwerk CK. An experimental basis for implicating excitotoxicity in glaucomatous optic neuropathy. Surv Ophthalmol 1999;43:S142-50.
    • (1999) Surv Ophthalmol , vol.43
    • Vorwerk, C.K.1
  • 19
    • 0031937195 scopus 로고    scopus 로고
    • A proposed role for excitotoxicity in glaucoma
    • Dreyer E. A proposed role for excitotoxicity in glaucoma. J Glaucoma 1998;7:62-7.
    • (1998) J Glaucoma , vol.7 , pp. 62-67
    • Dreyer, E.1
  • 20
    • 0030844267 scopus 로고    scopus 로고
    • Glaucoma, apoptosis, and neuroprotection
    • McKinnon SJ. Glaucoma, apoptosis, and neuroprotection. Curr Opin Ophthalmol 1997;8:28-37.
    • (1997) Curr Opin Ophthalmol , vol.8 , pp. 28-37
    • McKinnon, S.J.1
  • 21
    • 0032967382 scopus 로고    scopus 로고
    • The role of excitotoxicity in neurodegenerative disease: Implications for therapy
    • Doble A. The role of excitotoxicity in neurodegenerative disease: implications for therapy. Pharmacol Ther 1999;81:163-221.
    • (1999) Pharmacol Ther , vol.81 , pp. 163-221
    • Doble, A.1
  • 24
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis: An overview of cell death
    • Majno G, Joris J. Apoptosis, oncosis, and necrosis: an overview of cell death. Am J Pathol 1995;146:3-15.
    • (1995) Am J Pathol , vol.146 , pp. 3-15
    • Majno, G.1    Joris, J.2
  • 25
    • 0012583724 scopus 로고    scopus 로고
    • Mechanism of neuronal apoptosis
    • Haefliger IO, editor. Philadelphia, New York: Lippincott-Raven
    • Monard D. Mechanism of neuronal apoptosis. In: Haefliger IO, editor. Nitric oxide and endothelin in the pathogenesis of glaucoma. Philadelphia, New York: Lippincott-Raven, 1998:213-20.
    • (1998) Nitric Oxide and Endothelin in the Pathogenesis of Glaucoma , pp. 213-220
    • Monard, D.1
  • 26
    • 0021346318 scopus 로고
    • Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and macromolecular synthesis
    • Wyllie A, Morris RG, Smith AL, Dunlop D. Chromatin cleavage in apoptosis: association with condensed chromatin morphology and macromolecular synthesis. J Pathol 1984;142:67-77.
    • (1984) J Pathol , vol.142 , pp. 67-77
    • Wyllie, A.1    Morris, R.G.2    Smith, A.L.3    Dunlop, D.4
  • 27
    • 0026735829 scopus 로고
    • Fragmentation of DNA in the retina of chicken embryos coincides with retinal ganglion cell death
    • Ilschner SU, Waring P. Fragmentation of DNA in the retina of chicken embryos coincides with retinal ganglion cell death. Biochem Biophys Res Commun 1992;183:1056-61.
    • (1992) Biochem Biophys Res Commun , vol.183 , pp. 1056-1061
    • Ilschner, S.U.1    Waring, P.2
  • 28
    • 0028310855 scopus 로고
    • Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats
    • Berkelaar M, Clark DB, Wang YC, Bray GM, Aguayo AJ. Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. J Neurosci 1994;14:4368-74.
    • (1994) J Neurosci , vol.14 , pp. 4368-4374
    • Berkelaar, M.1    Clark, D.B.2    Wang, Y.C.3    Bray, G.M.4    Aguayo, A.J.5
  • 31
    • 0029069797 scopus 로고
    • Programmed cell death of retinal ganglion cells during experimental glaucoma
    • Garcia-Valenzuela E, Shareef S, Walsh J, Sharma SC. Programmed cell death of retinal ganglion cells during experimental glaucoma. Exp Eye Res 1995;61:33-44.
    • (1995) Exp Eye Res , vol.61 , pp. 33-44
    • Garcia-Valenzuela, E.1    Shareef, S.2    Walsh, J.3    Sharma, S.C.4
  • 32
    • 0018877393 scopus 로고
    • Chronic experimental glaucoma in primates. II. Effect of extended intraocular pressure elevation on optic nerve head and axonal transport
    • Quigley HA, Addicks EM. Chronic experimental glaucoma in primates. II. Effect of extended intraocular pressure elevation on optic nerve head and axonal transport. Invest Ophthalmol Vis Sci 1980;19:137-52.
    • (1980) Invest Ophthalmol Vis Sci , vol.19 , pp. 137-152
    • Quigley, H.A.1    Addicks, E.M.2
  • 33
    • 0026580615 scopus 로고
    • Cell death in rat retina after pressure-induced ischemia-reperfusion insult: Electron microscopy study. II. Outer nuclear layer
    • Buchi ER. Cell death in rat retina after pressure-induced ischemia-reperfusion insult: electron microscopy study. II. Outer nuclear layer. Jpn J Ophthalmol 1991;36:62-8.
    • (1991) Jpn J Ophthalmol , vol.36 , pp. 62-68
    • Buchi, E.R.1
  • 34
    • 0026483301 scopus 로고
    • Cell death in the rat retina after a pressure-induced ischemia-reperfusion insult: An electron microscopy study. I. Ganglion cell layer and inner nuclear layer
    • Buchi ER. Cell death in the rat retina after a pressure-induced ischemia-reperfusion insult: an electron microscopy study. I. Ganglion cell layer and inner nuclear layer. Exp Eye Res 1992;55:605-13.
    • (1992) Exp Eye Res , vol.55 , pp. 605-613
    • Buchi, E.R.1
  • 35
    • 0030755980 scopus 로고    scopus 로고
    • TUNEL-positive ganglion cells in human primary open-angle glaucoma
    • Kerrigan A. TUNEL-positive ganglion cells in human primary open-angle glaucoma. Arch Ophthalmol 1997;115:1031-5.
    • (1997) Arch Ophthalmol , vol.115 , pp. 1031-1035
    • Kerrigan, A.1
  • 36
    • 0029870073 scopus 로고    scopus 로고
    • Apoptosis of retinal ganglion cells in anterior optic neuropathy
    • Levin LA, Louhab A. Apoptosis of retinal ganglion cells in anterior optic neuropathy. Arch Ophthalmol 1996;114:488-91.
    • (1996) Arch Ophthalmol , vol.114 , pp. 488-491
    • Levin, L.A.1    Louhab, A.2
  • 37
    • 0022519440 scopus 로고
    • Brain derived neurorrophic factor supports the survival of cultured rat retinal ganglion cells
    • Johnson JE, Barde YA, Schwab M, Thoenen H. Brain derived neurorrophic factor supports the survival of cultured rat retinal ganglion cells. J Neurosci 1986;6:3031-8.
    • (1986) J Neurosci , vol.6 , pp. 3031-3038
    • Johnson, J.E.1    Barde, Y.A.2    Schwab, M.3    Thoenen, H.4
  • 38
    • 0028324822 scopus 로고
    • Effects of ocular injury and administration of brain derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells
    • Mansour-Robaey S, Clark DB, Wang YC, Bray GM, Aguayo AJ. Effects of ocular injury and administration of brain derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells. Proc Natl Acad Sci USA 1994;91:1632-6.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1632-1636
    • Mansour-Robaey, S.1    Clark, D.B.2    Wang, Y.C.3    Bray, G.M.4    Aguayo, A.J.5
  • 39
    • 0343460209 scopus 로고
    • Orthograde and retrograde axoplasmic transport during acute ocular hypertension in the monkey
    • Minckler DS, Bunt AH, Johanson GW. Orthograde and retrograde axoplasmic transport during acute ocular hypertension in the monkey. Invest Ophthalmol Vis Sci 1977;16:42-41.
    • (1977) Invest Ophthalmol Vis Sci , vol.16 , pp. 42-141
    • Minckler, D.S.1    Bunt, A.H.2    Johanson, G.W.3
  • 40
    • 0016240481 scopus 로고
    • Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerve
    • Anderson DR, Hendrickson A. Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerve. Invest Ophthalmol Vis Sci 1974:13:771-83.
    • (1974) Invest Ophthalmol Vis Sci , vol.13 , pp. 771-783
    • Anderson, D.R.1    Hendrickson, A.2
  • 41
    • 0017130467 scopus 로고
    • A light microscopic, autoradiographic study of axoplasmic transport in the optic nerve head during ocular hypotony, increased intraocular pressure, and papilledema
    • Minckler DS, Tso MO, Zimmerman LE. A light microscopic, autoradiographic study of axoplasmic transport in the optic nerve head during ocular hypotony, increased intraocular pressure, and papilledema. Am J Ophthalmol 1976;82:741-57.
    • (1976) Am J Ophthalmol , vol.82 , pp. 741-757
    • Minckler, D.S.1    Tso, M.O.2    Zimmerman, L.E.3
  • 42
    • 0017123773 scopus 로고
    • The dynamics and location of axonal transport blockade by acute intraocular pressure elevation in primate optic nerve
    • Quigley HA, Anderson DR. The dynamics and location of axonal transport blockade by acute intraocular pressure elevation in primate optic nerve. Invest Ophthalmol Vis Sci 1976;15:606-16.
    • (1976) Invest Ophthalmol Vis Sci , vol.15 , pp. 606-616
    • Quigley, H.A.1    Anderson, D.R.2
  • 43
    • 0017894234 scopus 로고
    • Radioautographic and cytochemical ultrastructure studies of axoplasmic transport in the monkey optic nerve head
    • Minckler DS, Bunt A, Klock IB. Radioautographic and cytochemical ultrastructure studies of axoplasmic transport in the monkey optic nerve head. Invest Ophthalmol Vis Sci 1978;17:33-50.
    • (1978) Invest Ophthalmol Vis Sci , vol.17 , pp. 33-50
    • Minckler, D.S.1    Bunt, A.2    Klock, I.B.3
  • 44
    • 0018348640 scopus 로고
    • Blockage of rapid axonal transport: Effect of intraocular pressure elevation in primate optic nerve
    • Quigley HA, Guy J, Anderson DR. Blockage of rapid axonal transport: effect of intraocular pressure elevation in primate optic nerve. Arch Ophthalmol 1979;97:525-31.
    • (1979) Arch Ophthalmol , vol.97 , pp. 525-531
    • Quigley, H.A.1    Guy, J.2    Anderson, D.R.3
  • 45
    • 0021924918 scopus 로고
    • Blockage at two points of axonal transport in glaucomatous eyes
    • Sakugawa M, Chihara E. Blockage at two points of axonal transport in glaucomatous eyes. Graefes Arch Clin Exp Ophthalmol 1985;223:214-8.
    • (1985) Graefes Arch Clin Exp Ophthalmol , vol.223 , pp. 214-218
    • Sakugawa, M.1    Chihara, E.2
  • 46
    • 0025817410 scopus 로고
    • Selective effects of experimental glaucoma on axonal transport by retinal ganglion cells to the dorsal lateral geniculate nucleus
    • Dandona L, Hendrickson A, Quigley HA. Selective effects of experimental glaucoma on axonal transport by retinal ganglion cells to the dorsal lateral geniculate nucleus. Invest Ophthalmol Vis Sci 1991;32:1593-9.
    • (1991) Invest Ophthalmol Vis Sci , vol.32 , pp. 1593-1599
    • Dandona, L.1    Hendrickson, A.2    Quigley, H.A.3
  • 47
    • 0016632271 scopus 로고
    • Slow axonal protein transport and visual function following retinal and optic nerve ischemia
    • Levy NS. Slow axonal protein transport and visual function following retinal and optic nerve ischemia. Invest Ophthalmol Vis Sci 1975;14:91-7.
    • (1975) Invest Ophthalmol Vis Sci , vol.14 , pp. 91-97
    • Levy, N.S.1
  • 48
    • 0017074102 scopus 로고
    • The effect of interruption of the short posterior ciliary arteries on slow axoplasmic transport and histology within the optic nerve of the rhesus monkey
    • Levy NS. The effect of interruption of the short posterior ciliary arteries on slow axoplasmic transport and histology within the optic nerve of the rhesus monkey. Invest Ophthalmol Vis Sci 1976;15:495-9.
    • (1976) Invest Ophthalmol Vis Sci , vol.15 , pp. 495-499
    • Levy, N.S.1
  • 49
    • 0019173257 scopus 로고
    • Optic nerve fast axonal transport abnormalities in primates: Occurrence after short posterior ciliary artery occlusion
    • Radius RL. Optic nerve fast axonal transport abnormalities in primates: occurrence after short posterior ciliary artery occlusion. Arch Ophthalmol 1980;98:2018-20.
    • (1980) Arch Ophthalmol , vol.98 , pp. 2018-2020
    • Radius, R.L.1
  • 50
    • 0019813454 scopus 로고
    • Morphology of axonal transport abnormalities in primate eyes
    • Radius RL. Morphology of axonal transport abnormalities in primate eyes. Br J Ophthalmol 1981;65:767-77.
    • (1981) Br J Ophthalmol , vol.65 , pp. 767-777
    • Radius, R.L.1
  • 51
    • 0019841314 scopus 로고
    • Pressure-induced optic nerve axonal transport interruption in cat eyes
    • Radius RL, Bade B. Pressure-induced optic nerve axonal transport interruption in cat eyes. Arch Ophthalmol 1981;99:2163-5.
    • (1981) Arch Ophthalmol , vol.99 , pp. 2163-2165
    • Radius, R.L.1    Bade, B.2
  • 52
    • 0027477946 scopus 로고
    • Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?
    • Beal MF, Hyman BT, Koroshetz W. Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases? Trends Neurosci 1993;16:125-31.
    • (1993) Trends Neurosci , vol.16 , pp. 125-131
    • Beal, M.F.1    Hyman, B.T.2    Koroshetz, W.3
  • 53
    • 0025242960 scopus 로고
    • Oxidation reactions in Parkinson's disease
    • Olanow CW. Oxidation reactions in Parkinson's disease. Neurology 1990;40(Suppl 3):32-3.
    • (1990) Neurology , vol.40 , Issue.SUPPL. 3 , pp. 32-33
    • Olanow, C.W.1
  • 54
    • 0028924168 scopus 로고
    • Oxidative stress in Parkinson's disease
    • Schapira AH. Oxidative stress in Parkinson's disease. Neuropathol Appl Neurobiol 1995;21:3-9.
    • (1995) Neuropathol Appl Neurobiol , vol.21 , pp. 3-9
    • Schapira, A.H.1
  • 55
    • 0032902973 scopus 로고    scopus 로고
    • Oxidative metabolism, apoptosis and perinatal brain injury
    • Taylor DL, Edwards D, Mehmet H. Oxidative metabolism, apoptosis and perinatal brain injury. Brain Pathol 1999;9:93-117.
    • (1999) Brain Pathol , vol.9 , pp. 93-117
    • Taylor, D.L.1    Edwards, D.2    Mehmet, H.3
  • 56
    • 0028905988 scopus 로고
    • Distribution of glutamate receptor subtypes in the vertebrate retina
    • Peng YW, Blackstone CD, Huganir RL, Yau KW. Distribution of glutamate receptor subtypes in the vertebrate retina. Neuroscience 1995;66:483-97.
    • (1995) Neuroscience , vol.66 , pp. 483-497
    • Peng, Y.W.1    Blackstone, C.D.2    Huganir, R.L.3    Yau, K.W.4
  • 58
    • 0026455172 scopus 로고
    • Interrelationship between retinal ischaemic damage and turnover and metabolism of putative amino acid neurotransmitters, glutamate and GABA
    • Robin LN, Kalloniatis M. Interrelationship between retinal ischaemic damage and turnover and metabolism of putative amino acid neurotransmitters, glutamate and GABA. Doc Ophthalmol 1992;80:273-300.
    • (1992) Doc Ophthalmol , vol.80 , pp. 273-300
    • Robin, L.N.1    Kalloniatis, M.2
  • 61
    • 0025942891 scopus 로고
    • N-methyl-D-aspartate antagonists prevent kainate neurotoxicity in rat retinal ganglion cells in vitro
    • Sucher NJ, Aizenman E, Lipton SA. N-methyl-D-aspartate antagonists prevent kainate neurotoxicity in rat retinal ganglion cells in vitro. J Neurosci 1991;11:966-71.
    • (1991) J Neurosci , vol.11 , pp. 966-971
    • Sucher, N.J.1    Aizenman, E.2    Lipton, S.A.3
  • 63
    • 0030987654 scopus 로고    scopus 로고
    • Elevated gamma-aminobutyric acid, glutamate, and vascular endothelial growth factor levels in the vitreous of patients with proliferative diabetic retinopathy
    • Ambati J, Chalam KV, Chawla DK, D'Angio CT, Guillet EG, Rose SJ, et al. Elevated gamma-aminobutyric acid, glutamate, and vascular endothelial growth factor levels in the vitreous of patients with proliferative diabetic retinopathy. Arch Ophthalmol 1997;115:1161-6.
    • (1997) Arch Ophthalmol , vol.115 , pp. 1161-1166
    • Ambati, J.1    Chalam, K.V.2    Chawla, D.K.3    D'Angio, C.T.4    Guillet, E.G.5    Rose, S.J.6
  • 68
    • 0027418959 scopus 로고
    • Foveal ganglion cell loss is size dependent in experimental glaucoma
    • Glovinsky Y, Quigley HA, Pease ME. Foveal ganglion cell loss is size dependent in experimental glaucoma. Invest Ophthalmol Vis Sci 1993;34:395-400.
    • (1993) Invest Ophthalmol Vis Sci , vol.34 , pp. 395-400
    • Glovinsky, Y.1    Quigley, H.A.2    Pease, M.E.3
  • 69
    • 0028073925 scopus 로고
    • Selective cell death in glaucoma: Does it really occur?
    • Morgan JE. Selective cell death in glaucoma: does it really occur? Br J Ophthalmol 1994;78:875-8.
    • (1994) Br J Ophthalmol , vol.78 , pp. 875-878
    • Morgan, J.E.1
  • 70
    • 0020971493 scopus 로고
    • Optic nerve axons and acquired alterations in the appearance of the optic disc
    • Wirtschafter JP. Optic nerve axons and acquired alterations in the appearance of the optic disc. Trans Am Ophthalmol Soc 1983;81:1034-91.
    • (1983) Trans Am Ophthalmol Soc , vol.81 , pp. 1034-1091
    • Wirtschafter, J.P.1
  • 71
    • 0342590239 scopus 로고
    • Large retinal ganglion cells are more susceptible to excitotoxicity and hypoxic injury than small cells
    • Caprioli J, Kitano S. Large retinal ganglion cells are more susceptible to excitotoxicity and hypoxic injury than small cells [abstract]. Invest Ophthalmol Vis Sci 1993;34(Suppl):1429.
    • (1993) Invest Ophthalmol Vis Sci , vol.34 , Issue.SUPPL. , pp. 1429
    • Caprioli, J.1    Kitano, S.2
  • 72
    • 0028206584 scopus 로고
    • Greater sensitivity of larger retinal ganglion cells to NMDA-mediated cell death
    • Dreyer EB, Pan ZH, Storm S, Lipton S. Greater sensitivity of larger retinal ganglion cells to NMDA-mediated cell death. Neuroreport 1994;6:629-31.
    • (1994) Neuroreport , vol.6 , pp. 629-631
    • Dreyer, E.B.1    Pan, Z.H.2    Storm, S.3    Lipton, S.4
  • 73
  • 74
    • 0025806264 scopus 로고
    • Calcium channel antagonists attenuate NMDA receptor-mediated neurotoxicity of retinal ganglion cells in culture
    • Sucher NJ. Calcium channel antagonists attenuate NMDA receptor-mediated neurotoxicity of retinal ganglion cells in culture. Brain Res 1991;551:297-302.
    • (1991) Brain Res , vol.551 , pp. 297-302
    • Sucher, N.J.1
  • 75
    • 0028097733 scopus 로고
    • The quantity of calcium that appears to induce neonatal death
    • Eimerl S, Schramm M. The quantity of calcium that appears to induce neonatal death. J Neurochem 1994;62:1223-6.
    • (1994) J Neurochem , vol.62 , pp. 1223-1226
    • Eimerl, S.1    Schramm, M.2
  • 76
    • 0027474041 scopus 로고
    • 2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration
    • 2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration. J Neurosci 1993;13:1993-2000.
    • (1993) J Neurosci , vol.13 , pp. 1993-2000
    • Hartley, D.1    Kurth, M.2    Bjerkness, L.3    Weiss, J.4    Choi, D.5
  • 77
    • 0027508237 scopus 로고
    • Prospects for clinically tolerated NMDA antagonists: Open-channel blockers and alternative redox states of nitric oxide
    • Lipton SA. Prospects for clinically tolerated NMDA antagonists: open-channel blockers and alternative redox states of nitric oxide. Trends Neurosci 1993;16:527-32.
    • (1993) Trends Neurosci , vol.16 , pp. 527-532
    • Lipton, S.A.1
  • 78
  • 79
    • 0024623852 scopus 로고
    • Selective modulation of NMDA responses by reduction and oxidation
    • Aizenman E, Lipton SA, Loring RH. Selective modulation of NMDA responses by reduction and oxidation. Neuron 1989;2:1257-63.
    • (1989) Neuron , vol.2 , pp. 1257-1263
    • Aizenman, E.1    Lipton, S.A.2    Loring, R.H.3
  • 80
    • 0010433344 scopus 로고    scopus 로고
    • NO-related species can protect from focal cerebral ischemia/reperfusion
    • Krieglstein J, Oberpichler-Schwenk H, editors. Stuttgart: Wissenschaftliche Verlagsgesellschaft
    • Lipton SA, Wang YF. NO-related species can protect from focal cerebral ischemia/reperfusion. In: Krieglstein J, Oberpichler-Schwenk H, editors. Pharmacology of cerebral ischemia. Stuttgart: Wissenschaftliche Verlagsgesellschaft, 1996.
    • (1996) Pharmacology of Cerebral Ischemia
    • Lipton, S.A.1    Wang, Y.F.2
  • 81
    • 0026632865 scopus 로고
    • Effect of nitric oxide production on the redox modulatory site of NMDA receptor-channel complex
    • Lei SZ, Pan ZH, Aggarwal SK, Chen HS, Hartman J, Sucher NJ, et al. Effect of nitric oxide production on the redox modulatory site of NMDA receptor-channel complex. Neuron 1992;8:1087-99.
    • (1992) Neuron , vol.8 , pp. 1087-1099
    • Lei, S.Z.1    Pan, Z.H.2    Aggarwal, S.K.3    Chen, H.S.4    Hartman, J.5    Sucher, N.J.6
  • 82
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurological disorders
    • Lipton SA. Excitatory amino acids as a final common pathway for neurological disorders. N Engl J Med 1994;330:613-22.
    • (1994) N Engl J Med , vol.330 , pp. 613-622
    • Lipton, S.A.1
  • 84
    • 0032078973 scopus 로고    scopus 로고
    • Nitrate therapy may retard glaucomatous optic neuropathy, perhaps through modulation of glutamate receptors
    • Zurakowski D, Vorwerk CK, Gorla M. Nitrate therapy may retard glaucomatous optic neuropathy, perhaps through modulation of glutamate receptors. Vision Res 1998;38:1489-94.
    • (1998) Vision Res , vol.38 , pp. 1489-1494
    • Zurakowski, D.1    Vorwerk, C.K.2    Gorla, M.3
  • 85
    • 0026701712 scopus 로고
    • Excitatory amino acid antagonists and their potential for the treatment of ischaemic brain damage in man
    • McCulloch J. Excitatory amino acid antagonists and their potential for the treatment of ischaemic brain damage in man. Br J Clin Pharmacol 1992;34:106-14.
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 106-114
    • McCulloch, J.1
  • 87
    • 0024365739 scopus 로고
    • The role of excitatory amino acids and NMDA receptors in traumatic brain injury
    • Faden AI, Demediuk P, Panter SS, Vink R. The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science 1989;244:798-800.
    • (1989) Science , vol.244 , pp. 798-800
    • Faden, A.I.1    Demediuk, P.2    Panter, S.S.3    Vink, R.4
  • 88
    • 0032967382 scopus 로고    scopus 로고
    • The role of excitotoxicity in neurodegenerative disease: Implications for therapy
    • Doble A. The role of excitotoxicity in neurodegenerative disease: implications for therapy. Pharmacol Ther 1999;81:163-221.
    • (1999) Pharmacol Ther , vol.81 , pp. 163-221
    • Doble, A.1
  • 89
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group
    • Bensimon G, Lacomblez L, Meininger V. A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. N Engl J Med 1994;330:585-91.
    • (1994) N Engl J Med , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 90
    • 0029977337 scopus 로고    scopus 로고
    • Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II
    • Lacomblez L, Bensimon G, Leigh PN, Guillet P, Meininger V. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II. Lancet 1996;347:425-31.
    • (1996) Lancet , vol.347 , pp. 425-431
    • Lacomblez, L.1    Bensimon, G.2    Leigh, P.N.3    Guillet, P.4    Meininger, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.