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Volumn 76, Issue , 2000, Pages 347-386

Hydroxyurea
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Author keywords

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Indexed keywords

HYDROXYUREA;

EID: 0033909973     PISSN: 02509555     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review
Times cited : (6)

References (200)
  • 1
    • 0019123075 scopus 로고
    • Hydroxyurea as a reference standard in teratological screening. Comparison of the embryotoxic and teratogenic effects following single intraperitoneal or repeated oral administrations to pregnant rats
    • Aliverti, V., Bonanomi, L. & Giavini, E. (1980) Hydroxyurea as a reference standard in teratological screening. Comparison of the embryotoxic and teratogenic effects following single intraperitoneal or repeated oral administrations to pregnant rats. Arch. Toxicol., Suppl. 4, 239-247
    • (1980) Arch. Toxicol. , Issue.SUPPL. 4 , pp. 239-247
    • Aliverti, V.1    Bonanomi, L.2    Giavini, E.3
  • 2
    • 0023114721 scopus 로고
    • The mutagenicity of 5-azacytidine and other inhibitors of replicative DNA synthesis in the L5178y mouse lymphoma cell
    • Amacher, D.E. & Turner, G.N. (1987) The mutagenicity of 5-azacytidine and other inhibitors of replicative DNA synthesis in the L5178Y mouse lymphoma cell. Mutat. Res., 176, 123-131
    • (1987) Mutat. Res. , vol.176 , pp. 123-131
    • Amacher, D.E.1    Turner, G.N.2
  • 3
    • 0003453785 scopus 로고    scopus 로고
    • Bethesda, MD, American Society of Health-System Pharmacists
    • American Hospital Formulary Service (1997) AHFS Drug Information® 97, Bethesda, MD, American Society of Health-System Pharmacists, pp. 766-770
    • (1997) AHFS Drug Information® 97 , pp. 766-770
  • 4
    • 0021333821 scopus 로고
    • Evidence for the involvement of cytochrome P-450-dependent monooxygenase(s) in the formation of genotoxic metabolites from N-hydroxyurea
    • Andrae, U. (1984) Evidence for the involvement of cytochrome P-450-dependent monooxygenase(s) in the formation of genotoxic metabolites from N-hydroxyurea. Biochem. biophys. Res. Commun., 118, 409-415
    • (1984) Biochem. Biophys. Res. Commun. , vol.118 , pp. 409-415
    • Andrae, U.1
  • 5
    • 0018387961 scopus 로고
    • Induction of DNA repair replication by hydroxyurea in human lymphoblastoid cells mediated by liver microsomes and NADPH
    • Andrae, U. & Greim, H. (1979) Induction of DNA repair replication by hydroxyurea in human lymphoblastoid cells mediated by liver microsomes and NADPH. Biochem. biophys. Res. Commun., 87, 50-58
    • (1979) Biochem. Biophys. Res. Commun. , vol.87 , pp. 50-58
    • Andrae, U.1    Greim, H.2
  • 6
    • 0025379349 scopus 로고
    • Myelodysplastic syndrome and secondary acute leukemia after treatment of essential thrombocythemia with hydroxyurea
    • van den Anker-Lugtenburg, P.J. & Sizoo, W. (1990) Myelodysplastic syndrome and secondary acute leukemia after treatment of essential thrombocythemia with hydroxyurea. Am. J. Hematol., 33, 152
    • (1990) Am. J. Hematol. , vol.33 , pp. 152
    • Van Den Anker-Lugtenburg, P.J.1    Sizoo, W.2
  • 7
    • 0022981489 scopus 로고
    • Hypersensitivity of Drosophila mei-4I mutants to hydroxyurea is associated with reduced mitotic chromosome stability
    • Banga, S.S., Shenkar, R. & Boyd, J.B. (1986) Hypersensitivity of Drosophila mei-4I mutants to hydroxyurea is associated with reduced mitotic chromosome stability. Mutat. Res., 163, 157-165
    • (1986) Mutat. Res. , vol.163 , pp. 157-165
    • Banga, S.S.1    Shenkar, R.2    Boyd, J.B.3
  • 8
    • 0023429121 scopus 로고
    • Induction of the SOS response by hydroxyurea in Escherichia coli K12
    • Barbé, J., Villaverde, A. & Guerrero, R. (1987) Induction of the SOS response by hydroxyurea in Escherichia coli K12. Mutat. Res., 192, 105-108
    • (1987) Mutat. Res. , vol.192 , pp. 105-108
    • Barbé, J.1    Villaverde, A.2    Guerrero, R.3
  • 9
    • 0019777355 scopus 로고
    • An exploration of the role of hydroxyurea injection time in fetal growth and terartogenesis in rats
    • Barr, M., Jr & Beaudoin, A.B. (1981) An exploration of the role of hydroxyurea injection time in fetal growth and terartogenesis in rats. Teratology, 24, 163-167
    • (1981) Teratology , vol.24 , pp. 163-167
    • Barr M., Jr.1    Beaudoin, A.B.2
  • 12
    • 0018956014 scopus 로고
    • Studies of hydroxyurea administered by continuous infusion: Toxicity, pharmacokinetics, and cell synchronization
    • Belt, R.J., Haas, C.D., Kennedy, J. & Taylor, S. (1980) Studies of hydroxyurea administered by continuous infusion: Toxicity, pharmacokinetics, and cell synchronization. Cancer, 46, 455-462
    • (1980) Cancer , vol.46 , pp. 455-462
    • Belt, R.J.1    Haas, C.D.2    Kennedy, J.3    Taylor, S.4
  • 13
    • 0031712803 scopus 로고    scopus 로고
    • Multiple skin cancers associated with hydroxyurea therapy
    • Best, P.J.M. & Petitt, R.M. (1998) Multiple skin cancers associated with hydroxyurea therapy. Mayo Clin. Proc., 73, 961-963
    • (1998) Mayo Clin. Proc. , vol.73 , pp. 961-963
    • Best, P.J.M.1    Petitt, R.M.2
  • 14
    • 0015877801 scopus 로고
    • Delayed effects of a single treatment of hydroxyurea to newborn mice
    • Bhide, S.V. & Sirsat, M.V. (1973) Delayed effects of a single treatment of hydroxyurea to newborn mice. Indian J. Cancer, 10, 26-30
    • (1973) Indian J. Cancer , vol.10 , pp. 26-30
    • Bhide, S.V.1    Sirsat, M.V.2
  • 17
    • 0342601969 scopus 로고    scopus 로고
    • London
    • British Medical Association/Royal Pharmaceutical Society of Great Britain (1998) British National Formulary, No. 36, London, p. 377
    • (1998) British National Formulary , Issue.36 , pp. 377
  • 18
    • 25344444824 scopus 로고
    • London, Her Majesty's Stationery Office
    • British Pharmacopoeial Commission (1993) British Pharmacopoeia 1993, London, Her Majesty's Stationery Office, Vols I & II, pp. 343, 954, S68
    • (1993) British Pharmacopoeia 1993 , vol.1-2 , pp. 343
  • 19
    • 0018643050 scopus 로고
    • The mutagenic activity of 61 agents as determined by the micronucleus, Salmonella, and sperm abnormality assays
    • Bruce, W.R. & Heddle, J.A. (1979) The mutagenic activity of 61 agents as determined by the micronucleus, Salmonella, and sperm abnormality assays. Can. J. Genet. Cytol., 21, 319-334
    • (1979) Can. J. Genet. Cytol. , vol.21 , pp. 319-334
    • Bruce, W.R.1    Heddle, J.A.2
  • 20
    • 0018182328 scopus 로고
    • A comparison of behavioral and anatomical measures of hydroxyurea induced abnormalities
    • Brunner, R.L., McLean, M., Vorhees, C.V. & Butcher, R.E. (1978) A comparison of behavioral and anatomical measures of hydroxyurea induced abnormalities. Teratology, 18, 379-384
    • (1978) Teratology , vol.18 , pp. 379-384
    • Brunner, R.L.1    McLean, M.2    Vorhees, C.V.3    Butcher, R.E.4
  • 21
    • 0003601534 scopus 로고    scopus 로고
    • Whitehouse Station, NJ, Merck & Co.
    • Budavari, S., ed. (1996) The Merck Index, 12th Ed., Whitehouse Station, NJ, Merck & Co., p. 833
    • (1996) The Merck Index, 12th Ed. , pp. 833
    • Budavari, S.1
  • 22
    • 0015608879 scopus 로고
    • Postnatal effects in rats of prenatal treatment with hydroxyurea
    • Butcher, R.E., Scott, W.J., Kazmaier, K. & Ritter, E.J. (1973) Postnatal effects in rats of prenatal treatment with hydroxyurea. Teratology, 7, 161-165
    • (1973) Teratology , vol.7 , pp. 161-165
    • Butcher, R.E.1    Scott, W.J.2    Kazmaier, K.3    Ritter, E.J.4
  • 23
    • 0028020235 scopus 로고
    • The induction of chromosomal damage and cell killing in mouse spermatogonial stem cells following combined treatments with hydroxyurea, 3-aminobenzamide and X-rays
    • van Buul, P.P. & Bootsma, A.L. (1994) The induction of chromosomal damage and cell killing in mouse spermatogonial stem cells following combined treatments with hydroxyurea, 3-aminobenzamide and X-rays. Mutat. Res., 311, 217-224
    • (1994) Mutat. Res. , vol.311 , pp. 217-224
    • Van Buul, P.P.1    Bootsma, A.L.2
  • 25
    • 0024543742 scopus 로고
    • Induction of specific locus mutations in mouse spermatogonial stem cells by combined chemical X-ray treatments
    • Cattanach, B.M., Peters, J. & Rasberry, C. (1989) Induction of specific locus mutations in mouse spermatogonial stem cells by combined chemical X-ray treatments. Mutat. Res., 212, 91-101
    • (1989) Mutat. Res. , vol.212 , pp. 91-101
    • Cattanach, B.M.1    Peters, J.2    Rasberry, C.3
  • 26
    • 0014930974 scopus 로고
    • Hydroxyurea: Suppression of two-stage carcinogenesis in mouse skin
    • Chan, P.C., Goldman, A. & Wynder, E.L. (1970) Hydroxyurea: Suppression of two-stage carcinogenesis in mouse skin. Science, 168, 130-132
    • (1970) Science , vol.168 , pp. 130-132
    • Chan, P.C.1    Goldman, A.2    Wynder, E.L.3
  • 27
  • 29
    • 0013934426 scopus 로고
    • The effects of hydroxyurea and related compounds on the rat fetus
    • Chaube, S. & Murphy, M.L. (1966) The effects of hydroxyurea and related compounds on the rat fetus. Cancer Res., 26, 1448-1457
    • (1966) Cancer Res. , vol.26 , pp. 1448-1457
    • Chaube, S.1    Murphy, M.L.2
  • 30
    • 0020682687 scopus 로고
    • Transforming activities of methotrexate, hydroxyurea and 5-fluorouracil in different cell systems
    • Chlopkiewicz, B. & Koziorowska, J.H. (1983) Transforming activities of methotrexate, hydroxyurea and 5-fluorouracil in different cell systems. Neoplasma, 30, 295-302
    • (1983) Neoplasma , vol.30 , pp. 295-302
    • Chlopkiewicz, B.1    Koziorowska, J.H.2
  • 32
    • 0030729450 scopus 로고    scopus 로고
    • Hydroxyurea-related ankle ulcers in patients with myeloproliferative disorders: A case report and review of the literature. Ann
    • Cox, C., Nowicky, D. & Young, R. (1997) Hydroxyurea-related ankle ulcers in patients with myeloproliferative disorders: A case report and review of the literature. Ann. plast. Surg., 39, 546-549
    • (1997) Plast. Surg. , vol.39 , pp. 546-549
    • Cox, C.1    Nowicky, D.2    Young, R.3
  • 33
    • 0030009603 scopus 로고    scopus 로고
    • Combination chemotherapy with hydroxyurea, dacarbazine (DTIC), and etoposide in the treatment of uterine leiomyosarcoma: A Gynecologic Oncology group study
    • Currie, J.L., Blessing, J.A., Muss, H.B., Fowler, J., Berman, M. & Burke, T.W. (1996a) Combination chemotherapy with hydroxyurea, dacarbazine (DTIC), and etoposide in the treatment of uterine leiomyosarcoma: A Gynecologic Oncology Group study. Gynecol. Oncol., 61, 27-30
    • (1996) Gynecol. Oncol. , vol.61 , pp. 27-30
    • Currie, J.L.1    Blessing, J.A.2    Muss, H.B.3    Fowler, J.4    Berman, M.5    Burke, T.W.6
  • 34
    • 0029872510 scopus 로고    scopus 로고
    • Phase II trial of hydroxyurea, dacarbazine (DTIC), and etoposide (VP-16) in mixed mesodermal tumors of the uterus: A Gynecologic Oncology group study
    • Currie, J.L., Blessing, J.A., McGehee, R., Soper, J.T. & Berman, M. (1996b) Phase II trial of hydroxyurea, dacarbazine (DTIC), and etoposide (VP-16) in mixed mesodermal tumors of the uterus: A Gynecologic Oncology Group study. Gynecol. Oncol., 61, 94-96
    • (1996) Gynecol. Oncol. , vol.61 , pp. 94-96
    • Currie, J.L.1    Blessing, J.A.2    McGehee, R.3    Soper, J.T.4    Berman, M.5
  • 35
    • 0032030703 scopus 로고    scopus 로고
    • Short communication. Translocation (1;20)(q32;q13.3) in myelofibrosis following polycythemia vera
    • Davidovitz, Y., Lev, D., Ballin, A., Tsudik, A. & Meytes, D. (1998) Short communication. Translocation (1;20)(q32;q13.3) in myelofibrosis following polycythemia vera. Cancer Genet. Cytogenet., 101, 156-158
    • (1998) Cancer Genet. Cytogenet. , vol.101 , pp. 156-158
    • Davidovitz, Y.1    Lev, D.2    Ballin, A.3    Tsudik, A.4    Meytes, D.5
  • 36
    • 0032504930 scopus 로고    scopus 로고
    • Target cell availability and the successful suppression of HIV by hydroxyurea and didanosine
    • De Boer, R.J., Boucher, C.A. & Perelson, A.S. (1998) Target cell availability and the successful suppression of HIV by hydroxyurea and didanosine. AIDS, 12, 1567-1570
    • (1998) AIDS , vol.12 , pp. 1567-1570
    • De Boer, R.J.1    Boucher, C.A.2    Perelson, A.S.3
  • 37
    • 0023814903 scopus 로고
    • Differential effects of DNA synthesis inhibitors on DNA methylation in normal and transformed cells
    • De Haan, J.B. & Parker, M.I. (1988) Differential effects of DNA synthesis inhibitors on DNA methylation in normal and transformed cells. Anticancer Res., 8, 617-620
    • (1988) Anticancer Res. , vol.8 , pp. 617-620
    • De Haan, J.B.1    Parker, M.I.2
  • 38
    • 0027055260 scopus 로고
    • Pregnancy during myelosuppressive treatment for chronic myelogenous leukaemia
    • Delmer, A., Rio, B., Bauduer, F., Ajchenbaum, F., Marie, J.-P. & Zittoun, R. (1992) Pregnancy during myelosuppressive treatment for chronic myelogenous leukaemia (Letter to the Editor). Br. J. Haematol., 82, 783-784
    • (1992) Br. J. Haematol. , vol.82 , pp. 783-784
    • Delmer, A.1    Rio, B.2    Bauduer, F.3    Ajchenbaum, F.4    Marie, J.-P.5    Zittoun, R.6
  • 39
    • 0020170932 scopus 로고
    • Comparison of teratogenic effects of aspirin and hydroxyurea in the Fischer 344 and Wistar strains
    • DePass, L.R. & Weaver, E.V. (1982) Comparison of teratogenic effects of aspirin and hydroxyurea in the Fischer 344 and Wistar strains. J. Toxicol. environ. Health, 10, 297-305
    • (1982) J. Toxicol. Environ. Health , vol.10 , pp. 297-305
    • DePass, L.R.1    Weaver, E.V.2
  • 40
    • 0019428462 scopus 로고
    • Comparative ultrastructural alterations in rabbit limb-buds after a teratogenic dose of either hydroxyurea or methotrexate
    • DeSesso, J.M. (1981a) Comparative ultrastructural alterations in rabbit limb-buds after a teratogenic dose of either hydroxyurea or methotrexate. Teratology, 23, 197-215
    • (1981) Teratology , vol.23 , pp. 197-215
    • DeSesso, J.M.1
  • 41
    • 0019769753 scopus 로고
    • Amelioration of teratogenesis. I. Modification of hydroxyurea-induced teratogenesis by the antioxidant propyl gallate
    • DeSesso, J.M. (1981b) Amelioration of teratogenesis. I. Modification of hydroxyurea-induced teratogenesis by the antioxidant propyl gallate. Teratology, 24, 19-35
    • (1981) Teratology , vol.24 , pp. 19-35
    • DeSesso, J.M.1
  • 42
    • 0025526401 scopus 로고
    • The nature of the embryo-protective interaction of propyl gallate with hydroxyurea
    • DeSesso, J.M. & Goeringer, G.C. (1990) The nature of the embryo-protective interaction of propyl gallate with hydroxyurea. Reprod. Toxicol., 4, 145-152
    • (1990) Reprod. Toxicol. , vol.4 , pp. 145-152
    • DeSesso, J.M.1    Goeringer, G.C.2
  • 43
    • 0017398784 scopus 로고
    • Drug-induced limb dysplasias in fetal rabbits
    • DeSesso, J.M. & Jordan, R.L. (1977) Drug-induced limb dysplasias in fetal rabbits. Teratology, 15, 199-211
    • (1977) Teratology , vol.15 , pp. 199-211
    • DeSesso, J.M.1    Jordan, R.L.2
  • 44
    • 0028299982 scopus 로고
    • D-Mannitol, a specific hydroxyl free radical scavenger, reduces the developmental toxicity of hydroxyurea in rabbits
    • DeSesso, J.M., Scialli, A.R. & Goeringer, G.C. (1994) D-Mannitol, a specific hydroxyl free radical scavenger, reduces the developmental toxicity of hydroxyurea in rabbits. Teratology; 49, 248-259
    • (1994) Teratology , vol.49 , pp. 248-259
    • DeSesso, J.M.1    Scialli, A.R.2    Goeringer, G.C.3
  • 45
  • 47
    • 0025884871 scopus 로고
    • Rapid development of multiple squamous-cell carcinomas during chronic granulocytic leukemia
    • Disdier, P., Harle, J.R., Grob, J.J., Weiller-Merli, C., Magalon, G. & Weiller, P.J. (1991) Rapid development of multiple squamous-cell carcinomas during chronic granulocytic leukemia. Dermatologica, 183, 47-48
    • (1991) Dermatologica , vol.183 , pp. 47-48
    • Disdier, P.1    Harle, J.R.2    Grob, J.J.3    Weiller-Merli, C.4    Magalon, G.5    Weiller, P.J.6
  • 48
    • 0026755811 scopus 로고
    • An overview of the clinical experience with hydroxyurea
    • Donehower, R.C. (1992) An overview of the clinical experience with hydroxyurea. Semin. Oncol., 19 (Suppl. 9), 11-19
    • (1992) Semin. Oncol. , vol.19 , Issue.SUPPL. 9 , pp. 11-19
    • Donehower, R.C.1
  • 49
    • 0018747775 scopus 로고
    • Combination chemotherapy for acute myelocytic leukemia during pregnancy: Three case reports
    • Doney, K.C., Kraemer, K.G. & Shepard, T.H. (1979) Combination chemotherapy for acute myelocytic leukemia during pregnancy: Three case reports. Cancer Treat. Rep., 63, 369-371
    • (1979) Cancer Treat. Rep. , vol.63 , pp. 369-371
    • Doney, K.C.1    Kraemer, K.G.2    Shepard, T.H.3
  • 53
    • 0027221914 scopus 로고
    • Hydroxyurea exposure alters mouse testicular kinetics and sperm chromatin structure
    • Evenson, D.P. & Jost, L.K. (1993) Hydroxyurea exposure alters mouse testicular kinetics and sperm chromatin structure. Cell Prolif., 26, 147-159
    • (1993) Cell Prolif. , vol.26 , pp. 147-159
    • Evenson, D.P.1    Jost, L.K.2
  • 54
    • 0028177356 scopus 로고
    • The origin of micronuclei induced by cytosine arabinoside and its synergistic interaction with hydroxyurea in human lymphocytes
    • Fenech, M., Rinaldi, J. & Surralles, J. (1994) The origin of micronuclei induced by cytosine arabinoside and its synergistic interaction with hydroxyurea in human lymphocytes. Mutagenesis, 9, 273-277
    • (1994) Mutagenesis , vol.9 , pp. 273-277
    • Fenech, M.1    Rinaldi, J.2    Surralles, J.3
  • 55
    • 0025313486 scopus 로고
    • Mutagenic and recombinogenic consequences of DNA-repair inhibition during treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea in Saccharomyces cerevisiae
    • Ferguson, L.R. (1990) Mutagenic and recombinogenic consequences of DNA-repair inhibition during treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea in Saccharomyces cerevisiae. Mutat. Res., 241, 369-377
    • (1990) Mutat. Res. , vol.241 , pp. 369-377
    • Ferguson, L.R.1
  • 56
    • 0002556839 scopus 로고
    • Mutagenic properties of anticancer drugs
    • Ponder, B.A.J. & Waring, M.J., eds, Lancaster, Kluwer Academic Publisher
    • Ferguson, L.R. (1995) Mutagenic properties of anticancer drugs. In: Ponder, B.A.J. & Waring, M.J., eds, The Genetics of Cancer, Lancaster, Kluwer Academic Publisher, pp. 177-216
    • (1995) The Genetics of Cancer , pp. 177-216
    • Ferguson, L.R.1
  • 57
    • 0029100275 scopus 로고
    • Anticancer drugs: An underestimated risk or an under-utilised resource in mutagenesis
    • Ferguson, L.R. & Denny, W.A. (1995) Anticancer drugs: An underestimated risk or an under-utilised resource in mutagenesis. Mutat. Res., 331, 1-26
    • (1995) Mutat. Res. , vol.331 , pp. 1-26
    • Ferguson, L.R.1    Denny, W.A.2
  • 58
    • 0023946498 scopus 로고
    • 'Petite' mutagenesis by anticancer drugs in Saccharomyces cerevisiae
    • Ferguson, L.R. & Turner, P.M. (1988a) 'Petite' mutagenesis by anticancer drugs in Saccharomyces cerevisiae. Eur. J. Cancer clin. Oncol., 24, 591-596
    • (1988) Eur. J. Cancer Clin. Oncol. , vol.24 , pp. 591-596
    • Ferguson, L.R.1    Turner, P.M.2
  • 59
    • 0023863353 scopus 로고
    • Mitotic crossing-over by anticancer drugs in Saccharomyces cerevisiae strain D5
    • Ferguson, L.R. & Turner, P.M. (1988b) Mitotic crossing-over by anticancer drugs in Saccharomyces cerevisiae strain D5. Mutat. Res., 204, 239-249
    • (1988) Mutat. Res. , vol.204 , pp. 239-249
    • Ferguson, L.R.1    Turner, P.M.2
  • 60
    • 0000195688 scopus 로고
    • Severe developmental malformations
    • Ferm, V.H. (1966) Severe developmental malformations. Arch. Pathol., 81, 174-177
    • (1966) Arch. Pathol. , vol.81 , pp. 174-177
    • Ferm, V.H.1
  • 62
    • 0027446929 scopus 로고
    • Hydroxyurea increases fetal hemoglobin in cultured erythroid cells derived from normal individuals and patients with sickle cell anemia or beta-thalassemia
    • Fibach, E., Burke, K.P., Schechter, A.N., Noguchi, C.T. & Rodgers, G.P. (1993) Hydroxyurea increases fetal hemoglobin in cultured erythroid cells derived from normal individuals and patients with sickle cell anemia or beta-thalassemia. Blood, 81, 1630-1635
    • (1993) Blood , vol.81 , pp. 1630-1635
    • Fibach, E.1    Burke, K.P.2    Schechter, A.N.3    Noguchi, C.T.4    Rodgers, G.P.5
  • 63
    • 0027418413 scopus 로고
    • The combination of hydroxyurea and leucapheresis in the treatment of chronic myeloid leukaemia in pregnancy
    • Fitzgerald, J.M. & McCann, S.R. (1993) The combination of hydroxyurea and leucapheresis in the treatment of chronic myeloid leukaemia in pregnancy. Clin. Lab. Haematol., 15, 63-65
    • (1993) Clin. Lab. Haematol. , vol.15 , pp. 63-65
    • Fitzgerald, J.M.1    McCann, S.R.2
  • 64
    • 0032543747 scopus 로고    scopus 로고
    • Therapeutic advantage of hydroxyurea and didanosine combination therapy in patients previously treated with zidovudine
    • Foli, A., Maserati, R., Minoli, L., Wainberg, M.A., Gallo, R.C., Lisziewicz, J. & Lori, F. (1998) Therapeutic advantage of hydroxyurea and didanosine combination therapy in patients previously treated with zidovudine. AIDS, 12, 1113-1114
    • (1998) AIDS , vol.12 , pp. 1113-1114
    • Foli, A.1    Maserati, R.2    Minoli, L.3    Wainberg, M.A.4    Gallo, R.C.5    Lisziewicz, J.6    Lori, F.7
  • 65
    • 0030064767 scopus 로고    scopus 로고
    • Acute myeloid leukemia evolving from essential thrombocythemia in two patients treated with hydroxyurea
    • Furgerson, J.L., Vukelja, S.J., Baker, W.J. & O'Rourke, T.J. (1996) Acute myeloid leukemia evolving from essential thrombocythemia in two patients treated with hydroxyurea. Am. J. Hematol., 51, 137-140
    • (1996) Am. J. Hematol. , vol.51 , pp. 137-140
    • Furgerson, J.L.1    Vukelja, S.J.2    Baker, W.J.3    O'Rourke, T.J.4
  • 66
    • 0030570423 scopus 로고    scopus 로고
    • Hydroxyurea induces recombination in dividing but not in G1 or G2 cell cycle arrested yeast cells
    • Galli, A. & Schiestl, R.H. (1996) Hydroxyurea induces recombination in dividing but not in G1 or G2 cell cycle arrested yeast cells. Mutat. Res., 354, 69-75
    • (1996) Mutat. Res. , vol.354 , pp. 69-75
    • Galli, A.1    Schiestl, R.H.2
  • 67
    • 0031832041 scopus 로고    scopus 로고
    • Cellular pharmacodynamics and plasma pharmacokinetics of parenterally infused hydroxyurea during a phase I clinical trial in chronic myelogenous leukemia
    • Gandhi, V., Plunkett, W., Kantarjian, H., Talpaz, M., Robertson, L.E. & O'Brien, S. (1998) Cellular pharmacodynamics and plasma pharmacokinetics of parenterally infused hydroxyurea during a phase I clinical trial in chronic myelogenous leukemia. J. clin. Oncol., 16, 2321-2331
    • (1998) J. Clin. Oncol. , vol.16 , pp. 2321-2331
    • Gandhi, V.1    Plunkett, W.2    Kantarjian, H.3    Talpaz, M.4    Robertson, L.E.5    O'Brien, S.6
  • 68
    • 0031721513 scopus 로고    scopus 로고
    • Role of the M2 subunit of ribonucleotide reductase in regulation by hydroxyurea of the activity of the anti-HIV-1 agent 2′,3′-dideoxyinosine
    • Gao, W. Y., Zhou, B.S., Johns, D.G., Mitsuya, H. & Yen, Y. (1998) Role of the M2 subunit of ribonucleotide reductase in regulation by hydroxyurea of the activity of the anti-HIV-1 agent 2′,3′-dideoxyinosine. Biochem. Pharmacol., 56, 105-112
    • (1998) Biochem. Pharmacol. , vol.56 , pp. 105-112
    • Gao, W.Y.1    Zhou, B.S.2    Johns, D.G.3    Mitsuya, H.4    Yen, Y.5
  • 70
    • 0342601926 scopus 로고
    • US Patent No. 2,705,727. Assigned to E.I. du Pont de Nemours & Co., Wilmington, DE
    • Graham, P.J. (1955) Synthesis of Ureas. US Patent No. 2,705,727. Assigned to E.I. du Pont de Nemours & Co., Wilmington, DE
    • (1955) Synthesis of Ureas
    • Graham, P.J.1
  • 71
    • 0032486088 scopus 로고    scopus 로고
    • Fewer chromosome aberrations and earlier apoptosis induced by DNA synthesis inhibitors, a topoisomerase II inhibitor or alkylating agents in human cells with normal compared with mutant p53
    • Greenwood, S.K., Armstrong, M.J., Hill, R.B., Bradt, C.I., Johnson, T.E., Hilliard, C.A. & Galloway, S.M. (1998) Fewer chromosome aberrations and earlier apoptosis induced by DNA synthesis inhibitors, a topoisomerase II inhibitor or alkylating agents in human cells with normal compared with mutant p53. Mutat. Res., 401, 39-53
    • (1998) Mutat. Res. , vol.401 , pp. 39-53
    • Greenwood, S.K.1    Armstrong, M.J.2    Hill, R.B.3    Bradt, C.I.4    Johnson, T.E.5    Hilliard, C.A.6    Galloway, S.M.7
  • 72
    • 0027497147 scopus 로고
    • Nail and skin hyperpigmentation associated with hydroxyurea therapy for polycythemia vera
    • Gropper, C.A., Don, P.C. & Sadjadi, M.M. (1993) Nail and skin hyperpigmentation associated with hydroxyurea therapy for polycythemia vera. Int. J. Dermatol., 32, 731-733
    • (1993) Int. J. Dermatol. , vol.32 , pp. 731-733
    • Gropper, C.A.1    Don, P.C.2    Sadjadi, M.M.3
  • 74
    • 0031923969 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of hydroxyurea
    • Gwilt, P.R. & Tracewell, W.G. (1998) Pharmacokinetics and pharmacodynamics of hydroxyurea. Clin. Pharmacokinet., 34, 347-358
    • (1998) Clin. Pharmacokinet. , vol.34 , pp. 347-358
    • Gwilt, P.R.1    Tracewell, W.G.2
  • 75
    • 0022533130 scopus 로고
    • Chromosomal changes without DNA overproduction in hydroxyurea-treated mammalian cells: Implications for gene amplification
    • Hahn, P., Kapp, L.N., Morgan, W.F. & Painter, R.B. (1986) Chromosomal changes without DNA overproduction in hydroxyurea-treated mammalian cells: Implications for gene amplification. Cancer Res., 46, 4607-4612
    • (1986) Cancer Res. , vol.46 , pp. 4607-4612
    • Hahn, P.1    Kapp, L.N.2    Morgan, W.F.3    Painter, R.B.4
  • 76
    • 0028906754 scopus 로고
    • Partial attenuation of hydroxyurea-induced embryotoxicity by deoxyribonucleotides in mouse and rat embryos treated in vitro
    • Hansen, D.K., Grafton, T.F., Cross, D.R. & James, S.J. (1995) Partial attenuation of hydroxyurea-induced embryotoxicity by deoxyribonucleotides in mouse and rat embryos treated in vitro. Toxicol. in Vitro, 9, 11-19
    • (1995) Toxicol. in Vitro , vol.9 , pp. 11-19
    • Hansen, D.K.1    Grafton, T.F.2    Cross, D.R.3    James, S.J.4
  • 77
    • 0020534259 scopus 로고
    • Induction of micronuclei in the mouse. Revised timing of the final stage of erythropoiesis
    • Hart, J.W. & Hartley-Asp, B. (1983) Induction of micronuclei in the mouse. Revised timing of the final stage of erythropoiesis. Mutat. Res., 120, 127-132
    • (1983) Mutat. Res. , vol.120 , pp. 127-132
    • Hart, J.W.1    Hartley-Asp, B.2
  • 78
    • 0021042686 scopus 로고
    • Salmonella mutagenicity test results for 250 chemicals
    • Haworth, S., Lawlor, T., Mortelmans, K., Speck, W. & Zeiger, E. (1983) Salmonella mutagenicity test results for 250 chemicals. Environ. Mutag., 5 (Suppl. 1), 3-142
    • (1983) Environ. Mutag. , vol.5 , Issue.SUPPL. 1 , pp. 3-142
    • Haworth, S.1    Lawlor, T.2    Mortelmans, K.3    Speck, W.4    Zeiger, E.5
  • 79
    • 0021177912 scopus 로고
    • The influence of deoxycytidine monophosphate (dCMP) on the cytotoxicity of hydroxyurea in the embryonic spinal cord of the mouse
    • Herken, R. (1984) The influence of deoxycytidine monophosphate (dCMP) on the cytotoxicity of hydroxyurea in the embryonic spinal cord of the mouse. Teratology, 30, 83-90
    • (1984) Teratology , vol.30 , pp. 83-90
    • Herken, R.1
  • 80
    • 0021826268 scopus 로고
    • Ultrastructural changes in the neural tube of 10-day-old mouse embryos exposed to colchicine and hydroxyurea
    • Herken, R. (1985) Ultrastructural changes in the neural tube of 10-day-old mouse embryos exposed to colchicine and hydroxyurea. Teratology, 31, 345-352
    • (1985) Teratology , vol.31 , pp. 345-352
    • Herken, R.1
  • 81
    • 0022385486 scopus 로고
    • Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations
    • Hill, A.B. & Schimke, R.T. (1985) Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations. Cancer Res., 45, 5050-5057
    • (1985) Cancer Res. , vol.45 , pp. 5050-5057
    • Hill, A.B.1    Schimke, R.T.2
  • 82
    • 0025779626 scopus 로고
    • Chronic myelomonocytic leukemia transformation in polycythemia vera
    • Holcombe, R.F., Treseler, P.A. & Rosenthal, D.S. (1991) Chronic myelomonocytic leukemia transformation in polycythemia vera. Leukemia, 5, 606-610
    • (1991) Leukemia , vol.5 , pp. 606-610
    • Holcombe, R.F.1    Treseler, P.A.2    Rosenthal, D.S.3
  • 83
    • 0018822521 scopus 로고
    • Effects of inhibitors of DNA synthesis on spontaneous and ultraviolet light-induced sister-chromatid exchanges in Chinese hamster cells
    • Ishii, Y. & Bender, M.A. (1980) Effects of inhibitors of DNA synthesis on spontaneous and ultraviolet light-induced sister-chromatid exchanges in Chinese hamster cells. Mutat. Res., 79, 19-32
    • (1980) Mutat. Res. , vol.79 , pp. 19-32
    • Ishii, Y.1    Bender, M.A.2
  • 84
    • 0020316105 scopus 로고
    • Enhancement of methylnitrosourea skin carcinogenesis by inhibiting cell proliferation with hydroxyurea or skin extracts
    • Iversen, O.H. (1982a) Enhancement of methylnitrosourea skin carcinogenesis by inhibiting cell proliferation with hydroxyurea or skin extracts. Carcinogenesis, 3, 881-889
    • (1982) Carcinogenesis , vol.3 , pp. 881-889
    • Iversen, O.H.1
  • 85
    • 0020321550 scopus 로고
    • Hydroxyurea enhances methylnitrosourea skin carcinogenesis when given shortly before, but not after, the carcinogen
    • Iversen, O.H. (1982b) Hydroxyurea enhances methylnitrosourea skin carcinogenesis when given shortly before, but not after, the carcinogen. Carcinogenesis, 3, 891-894
    • (1982) Carcinogenesis , vol.3 , pp. 891-894
    • Iversen, O.H.1
  • 86
    • 0021017148 scopus 로고
    • Limb deformity induced in chick embryo by hydroxyurea
    • Iwama, M., Sakamoto, Y., Honda, A. & Mori, Y. (1983) Limb deformity induced in chick embryo by hydroxyurea. J. Pharmacobiodyn., 6, 836-843
    • (1983) J. Pharmacobiodyn. , vol.6 , pp. 836-843
    • Iwama, M.1    Sakamoto, Y.2    Honda, A.3    Mori, Y.4
  • 87
    • 0027374033 scopus 로고
    • Hydroxyurea treatment for chronic myeloid leukaemia during pregnancy
    • Jackson, H., Shukri, A. & Ali, K. (1993) Hydroxyurea treatment for chronic myeloid leukaemia during pregnancy. Br. J. Haematol., 85, 203-204
    • (1993) Br. J. Haematol. , vol.85 , pp. 203-204
    • Jackson, H.1    Shukri, A.2    Ali, K.3
  • 88
    • 0030591660 scopus 로고    scopus 로고
    • Genetic activity profiles of anticancer drugs
    • Jackson, M.A., Stack, H.F. & Waters, M.D. (1996) Genetic activity profiles of anticancer drugs. Mutat. Res., 355, 171-208
    • (1996) Mutat. Res. , vol.355 , pp. 171-208
    • Jackson, M.A.1    Stack, H.F.2    Waters, M.D.3
  • 89
    • 0026651238 scopus 로고
    • Enhanced cytogenetic detection of previous in vivo exposure to mutagens in human lymphocytes after treatment with inhibitors of DNA synthesis and DNA repair in vitro
    • Jelmert, Ø., Hansteen, I.-L. & Langård, S. (1992) Enhanced cytogenetic detection of previous in vivo exposure to mutagens in human lymphocytes after treatment with inhibitors of DNA synthesis and DNA repair in vitro. Mutat. Res., 271, 289-298
    • (1992) Mutat. Res. , vol.271 , pp. 289-298
    • Jelmert, Ø.1    Hansteen, I.-L.2    Langård, S.3
  • 90
    • 0031468478 scopus 로고    scopus 로고
    • In vivo production of nitric oxide in rats after administration of hydroxyurea
    • Jiang, J., Jordan, S.J., Barr, D.P., Gunther, M.R., Maeda, H. & Mason, R.P. (1997) In vivo production of nitric oxide in rats after administration of hydroxyurea. Mol. Pharmacol., 52, 1081-1086
    • (1997) Mol. Pharmacol. , vol.52 , pp. 1081-1086
    • Jiang, J.1    Jordan, S.J.2    Barr, D.P.3    Gunther, M.R.4    Maeda, H.5    Mason, R.P.6
  • 91
    • 0032524983 scopus 로고    scopus 로고
    • Selective depletion of DNA precursors: An evolving strategy for potentiation of dideoxynucleoside activity against immunodeficiency virus
    • Johns, D.G. & Gao, W.Y. (1998) Selective depletion of DNA precursors: An evolving strategy for potentiation of dideoxynucleoside activity against immunodeficiency virus. Biochem. Pharmacol., 55, 1551-1556
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1551-1556
    • Johns, D.G.1    Gao, W.Y.2
  • 93
    • 0015496209 scopus 로고
    • Chromatid breakage: Differential effect of inhibitors of DNA synthesis during G2 phase
    • Karon, M. & Benedict, W.F. (1972) Chromatid breakage: Differential effect of inhibitors of DNA synthesis during G2 phase. Science, 178, 62
    • (1972) Science , vol.178 , pp. 62
    • Karon, M.1    Benedict, W.F.2
  • 94
    • 0018613975 scopus 로고
    • A teratogenicity study on hydroxyurea and diphenylhydantoin in cats
    • Khera, K.S. (1979) A teratogenicity study on hydroxyurea and diphenylhydantoin in cats. Teratology, 20, 447-452
    • (1979) Teratology , vol.20 , pp. 447-452
    • Khera, K.S.1
  • 95
    • 0022260692 scopus 로고
    • Synergistic enhancement of the frequency of chromatid aberrations in cultured human lymphocytes by combinations of inhibitors of DNA repair
    • Kihlman, B.A. & Andersson, H.C. (1985) Synergistic enhancement of the frequency of chromatid aberrations in cultured human lymphocytes by combinations of inhibitors of DNA repair. Mutat. Res., 150, 313-325
    • (1985) Mutat. Res. , vol.150 , pp. 313-325
    • Kihlman, B.A.1    Andersson, H.C.2
  • 96
    • 0024352020 scopus 로고
    • Cell cycle dependence of N-methyl-N-nitrosourea-induced tumour development in the proliferating, partially resected urinary bladder
    • Kunze, E., Graewe, T., Scherber, S., Weber, J. & Gellhar, P. (1989) Cell cycle dependence of N-methyl-N-nitrosourea-induced tumour development in the proliferating, partially resected urinary bladder. Br. J. exp. Pathol., 70, 125-142
    • (1989) Br. J. Exp. Pathol. , vol.70 , pp. 125-142
    • Kunze, E.1    Graewe, T.2    Scherber, S.3    Weber, J.4    Gellhar, P.5
  • 97
    • 0020503289 scopus 로고
    • DNA repair replication, DNA breaks and sister-chromatid exchange in human cells treated with adriamycin in vitro
    • Lambert, B., Sten, M., Söderhäll, S., Ringborg, U. & Lewensohn, R. (1983) DNA repair replication, DNA breaks and sister-chromatid exchange in human cells treated with adriamycin in vitro. Mutat. Res., 111, 171-184
    • (1983) Mutat. Res. , vol.111 , pp. 171-184
    • Lambert, B.1    Sten, M.2    Söderhäll, S.3    Ringborg, U.4    Lewensohn, R.5
  • 98
    • 0022706609 scopus 로고
    • Acute leukemia in polycythemia vera
    • Landaw, S.A. (1986) Acute leukemia in polycythemia vera. Semin. Hematol., 23, 156-165
    • (1986) Semin. Hematol. , vol.23 , pp. 156-165
    • Landaw, S.A.1
  • 99
    • 0026695162 scopus 로고
    • Treatment of recurrent gliomas and metastatic brain tumors with a polydrug protocol designed to combat nitrosourea resistance
    • Levin, V.A. & Prados, M.D. (1992) Treatment of recurrent gliomas and metastatic brain tumors with a polydrug protocol designed to combat nitrosourea resistance. J. clin. Oncol., 10, 766-771
    • (1992) J. Clin. Oncol. , vol.10 , pp. 766-771
    • Levin, V.A.1    Prados, M.D.2
  • 100
    • 0023237949 scopus 로고
    • Progressive formation of DNA lesions in cultured Ehrlich ascites tumor cells treated with hydroxyurea
    • Li, J.C. & Kaminskas, E. (1987) Progressive formation of DNA lesions in cultured Ehrlich ascites tumor cells treated with hydroxyurea. Cancer Res., 47, 2755-2758
    • (1987) Cancer Res. , vol.47 , pp. 2755-2758
    • Li, J.C.1    Kaminskas, E.2
  • 101
    • 0030995141 scopus 로고    scopus 로고
    • Is treatment with hydroxyurea leukemogenic in patients with essential thrombocythemia? An analysis of three new cases of leukaemic transformation and review of the literature
    • Liozon, E., Brigaudeau, C., Trimoreau, F., Desangles, F., Fermeaux, V., Praloran, V. & Bordessoule, D. (1997) Is treatment with hydroxyurea leukemogenic in patients with essential thrombocythemia? An analysis of three new cases of leukaemic transformation and review of the literature. Hematol. Cell Ther., 39, 11-18
    • (1997) Hematol. Cell Ther. , vol.39 , pp. 11-18
    • Liozon, E.1    Brigaudeau, C.2    Trimoreau, F.3    Desangles, F.4    Fermeaux, V.5    Praloran, V.6    Bordessoule, D.7
  • 102
    • 0032543873 scopus 로고    scopus 로고
    • HIV-1 suppression by early treatment with hydroxyurea, didanosine, and a protease inhibitor
    • Lisziewicz, J., Jessen, H., Finzi, D., Siliciano, R.F. & Lori, F. (1998) HIV-1 suppression by early treatment with hydroxyurea, didanosine, and a protease inhibitor. Lancet, 352, 199-200
    • (1998) Lancet , vol.352 , pp. 199-200
    • Lisziewicz, J.1    Jessen, H.2    Finzi, D.3    Siliciano, R.F.4    Lori, F.5
  • 103
    • 0024212665 scopus 로고
    • Management of polycythaemia vera, essential thrombocythaemia and myelofibrosis with hydroxyurea
    • Löfvenberg, E. & Wahlin, A. (1988) Management of polycythaemia vera, essential thrombocythaemia and myelofibrosis with hydroxyurea. Eur. J. Haematol., 41, 375-381
    • (1988) Eur. J. Haematol. , vol.41 , pp. 375-381
    • Löfvenberg, E.1    Wahlin, A.2
  • 104
    • 0025009008 scopus 로고
    • Cytogenetic abnormalities and leukemic transformation in hydroxyurea-treated patients with philadelphia chromosome negative chronic myeloproliferative disease
    • Löfvenberg, E., Nordenson, I. & Wahlin, A. (1990) Cytogenetic abnormalities and leukemic transformation in hydroxyurea-treated patients with Philadelphia chromosome negative chronic myeloproliferative disease. Cancer Genet. Cytogenet., 49, 57-67
    • (1990) Cancer Genet. Cytogenet. , vol.49 , pp. 57-67
    • Löfvenberg, E.1    Nordenson, I.2    Wahlin, A.3
  • 105
    • 0030841371 scopus 로고    scopus 로고
    • Didanosine but not high doses of hydroxyurea rescue pigtail macaque from a lethal dose of SIV (smmpbj14)
    • Lori, F., Gallo, R.C., Malykh, A., Cara, A., Romano, J., Markham, P. & Franchini, G. (1997a) Didanosine but not high doses of hydroxyurea rescue pigtail macaque from a lethal dose of SIV (smmpbj14). AIDS Res. hum. Retroviruses, 13, 1083-1088
    • (1997) AIDS Res. Hum. Retroviruses , vol.13 , pp. 1083-1088
    • Lori, F.1    Gallo, R.C.2    Malykh, A.3    Cara, A.4    Romano, J.5    Markham, P.6    Franchini, G.7
  • 108
    • 0031693813 scopus 로고    scopus 로고
    • Pharmacokinetics, safety and anti-human immunodeficiency virus (HIV) activity of hydroxyurea in combination with didanosine
    • Luzzati, R., Di-Perri, G., Fendt, D., Ramarli, D., Broccali, G. & Concia, E. (1998) Pharmacokinetics, safety and anti-human immunodeficiency virus (HIV) activity of hydroxyurea in combination with didanosine (Letter). J. antimicrob. Chemother., 42, 565-566
    • (1998) J. Antimicrob. Chemother. , vol.42 , pp. 565-566
    • Luzzati, R.1    Di-Perri, G.2    Fendt, D.3    Ramarli, D.4    Broccali, G.5    Concia, E.6
  • 109
    • 0031809842 scopus 로고    scopus 로고
    • Fetal hemoglobin and F-cell responses to long-term hydroxyurea treatment in young sickle cell patients
    • Maier-Redelsperger, M., de Montalembert, M., Flahault, A., Neonato, M.G., Ducrocq, R., Masson, M.P., Girot, R. & Elion, J. for the French Study Group on Sickle Cell Disease (1998) Fetal hemoglobin and F-cell responses to long-term hydroxyurea treatment in young sickle cell patients. Blood, 91, 4472-4479
    • (1998) Blood , vol.91 , pp. 4472-4479
    • Maier-Redelsperger, M.1    De Montalembert, M.2    Flahault, A.3    Neonato, M.G.4    Ducrocq, R.5    Masson, M.P.6    Girot, R.7    Elion, J.8
  • 110
    • 0025340286 scopus 로고
    • Mutations induced at the hypoxanthineguanine phosphoribosyltransferase locus of human T-lymphoblasts by perturbations of purine deoxyribonucleoside triphosphate pools
    • Mattano, S.S., Palella, T.D. & Mitchell, B.S. (1990) Mutations induced at the hypoxanthineguanine phosphoribosyltransferase locus of human T-lymphoblasts by perturbations of purine deoxyribonucleoside triphosphate pools. Cancer Res., 50, 4566-4571
    • (1990) Cancer Res. , vol.50 , pp. 4566-4571
    • Mattano, S.S.1    Palella, T.D.2    Mitchell, B.S.3
  • 111
    • 0022620279 scopus 로고
    • Aneuploidy and other genetic effects induced by hydroxyurea in Saccharomyces cerevisiae
    • Mayer, V.W., Goin, C.J. & Zimmermann, F.K. (1986) Aneuploidy and other genetic effects induced by hydroxyurea in Saccharomyces cerevisiae. Mutat. Res., 160, 19-26
    • (1986) Mutat. Res. , vol.160 , pp. 19-26
    • Mayer, V.W.1    Goin, C.J.2    Zimmermann, F.K.3
  • 113
    • 0021601350 scopus 로고
    • Different effects of mutagens on sister chromatid exchange induction in three Chinese hamster cell lines
    • Mehnert, K., Vogel, W., Benz, R. & Speit, G. (1984) Different effects of mutagens on sister chromatid exchange induction in three Chinese hamster cell lines. Environ. Mutag., 6, 573-583
    • (1984) Environ. Mutag. , vol.6 , pp. 573-583
    • Mehnert, K.1    Vogel, W.2    Benz, R.3    Speit, G.4
  • 114
    • 0019404777 scopus 로고
    • Effects of hydroxyurea on hemodynamics of pregnant rabbits: A maternally mediated mechanism of embryotoxicity
    • Millicovsky, G., DeSesso, J.M., Kleinman, L.I. & Clark, K.E. (1981) Effects of hydroxyurea on hemodynamics of pregnant rabbits: A maternally mediated mechanism of embryotoxicity. Am. J. Obstet. Gynecol., 140, 747-752
    • (1981) Am. J. Obstet. Gynecol. , vol.140 , pp. 747-752
    • Millicovsky, G.1    DeSesso, J.M.2    Kleinman, L.I.3    Clark, K.E.4
  • 115
    • 0021720527 scopus 로고
    • Enhancement of the DNA breakage and cytotoxic effects of intercalating agents by treatment with sublethal doses of 1-beta-D-arabinofuranosylcytosine or hydroxyurea in L1210 cells
    • Minford, J., Kerrigan, D., Nichols, M., Shackney, S. & Zwelling, L.A. (1984) Enhancement of the DNA breakage and cytotoxic effects of intercalating agents by treatment with sublethal doses of 1-beta-D-arabinofuranosylcytosine or hydroxyurea in L1210 cells. Cancer Res., 44, 5583-5593
    • (1984) Cancer Res. , vol.44 , pp. 5583-5593
    • Minford, J.1    Kerrigan, D.2    Nichols, M.3    Shackney, S.4    Zwelling, L.A.5
  • 117
    • 0030956535 scopus 로고    scopus 로고
    • A pilot study of hydroxyurea among patients with advanced human immunodeficiency virus (HIV) disease receiving chronic didanosine therapy: Canadian HIV trials network protocol 080
    • Montaner, J.S., Zala, C., Conway, B., Raboud, J., Patenaude, P., Rae, S., O'Shaughnessy, M.V. & Schechter, M.T. (1997) A pilot study of hydroxyurea among patients with advanced human immunodeficiency virus (HIV) disease receiving chronic didanosine therapy: Canadian HIV trials network protocol 080. J. infect. Dis., 175, 801-806
    • (1997) J. Infect. Dis. , vol.175 , pp. 801-806
    • Montaner, J.S.1    Zala, C.2    Conway, B.3    Raboud, J.4    Patenaude, P.5    Rae, S.6    O'Shaughnessy, M.V.7    Schechter, M.T.8
  • 118
    • 0015593351 scopus 로고
    • Psoriasis with hydroxyurea. An 18-month study of 60 patients
    • Moschella, S.L. & Greenwald, M.A. (1973) Psoriasis with hydroxyurea. An 18-month study of 60 patients. Arch. Dermatol., 107, 363-368
    • (1973) Arch. Dermatol. , vol.107 , pp. 363-368
    • Moschella, S.L.1    Greenwald, M.A.2
  • 119
    • 0015268834 scopus 로고
    • Comparative study of carcinogenic activity of hydroxyurea and urethane in XVII-G mice
    • Muranyi-Kovacs, I. & Rudali, G. (1972) Comparative study of carcinogenic activity of hydroxyurea and urethane in XVII-G mice. Rev. Eur. Etud. clin. biol., 17, 93-95
    • (1972) Rev. Eur. Etud. Clin. Biol. , vol.17 , pp. 93-95
    • Muranyi-Kovacs, I.1    Rudali, G.2
  • 120
    • 0007088448 scopus 로고
    • Preliminary survey of hydroxyurea (NSC-32065) as a teratogen
    • Murphy, M.L. & Chaube, S. (1964) Preliminary survey of hydroxyurea (NSC-32065) as a teratogen. Cancer Chemother. Rep., 40, 1-7
    • (1964) Cancer Chemother. Rep. , vol.40 , pp. 1-7
    • Murphy, M.L.1    Chaube, S.2
  • 122
    • 0030784247 scopus 로고    scopus 로고
    • Treatment of polycythemia vera: The use of hydroxyurea and pipobroman in 292 patients under the age of 65 years
    • Najean, Y. & Rain, J.-D. (1997a) Treatment of polycythemia vera: The use of hydroxyurea and pipobroman in 292 patients under the age of 65 years. Blood, 90, 3370-3377
    • (1997) Blood , vol.90 , pp. 3370-3377
    • Najean, Y.1    Rain, J.-D.2
  • 123
    • 0031000705 scopus 로고    scopus 로고
    • 32P alone or in combination with maintenance therapy using hydroxyurea in 461 patients greater than 65 years of age
    • 32P alone or in combination with maintenance therapy using hydroxyurea in 461 patients greater than 65 years of age. Blood, 89, 2319-2327
    • (1997) Blood , vol.89 , pp. 2319-2327
    • Najean, Y.1    Rain, J.D.2
  • 126
    • 0030011932 scopus 로고    scopus 로고
    • Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Nand, S., Stock, W., Godwin, J. & Fisher, S.G. (1996) Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Am. J. Hematol., 52, 42-46
    • (1996) Am. J. Hematol. , vol.52 , pp. 42-46
    • Nand, S.1    Stock, W.2    Godwin, J.3    Fisher, S.G.4
  • 128
    • 0029557303 scopus 로고
    • Anticancer drug toxicity via cytokine production: The hydroxyurea paradigm
    • Navarra, P., Puccetti, P., Riccardi, C. & Preziosi, P. (1995) Anticancer drug toxicity via cytokine production: The hydroxyurea paradigm. Toxicol. Lett., 82-83, 167-171
    • (1995) Toxicol. Lett. , vol.82-83 , pp. 167-171
    • Navarra, P.1    Puccetti, P.2    Riccardi, C.3    Preziosi, P.4
  • 129
    • 0029938532 scopus 로고    scopus 로고
    • The effects of inhibitors of cyclo-oxygenase, lipoxygenase and nitric oxide synthase pathways on the toxicity of hydroxyurea in adrenalectomized rats
    • Navarra, P., Tringali, G. & Preziosi, P. (1996) The effects of inhibitors of cyclo-oxygenase, lipoxygenase and nitric oxide synthase pathways on the toxicity of hydroxyurea in adrenalectomized rats. Toxicol. Lett., 86, 13-18
    • (1996) Toxicol. Lett. , vol.86 , pp. 13-18
    • Navarra, P.1    Tringali, G.2    Preziosi, P.3
  • 131
    • 0031659881 scopus 로고    scopus 로고
    • Hydroxyurea influences adrenocortical function in humans
    • Navarra, P., Tringali, G. & Preziosi, P. (1998) Hydroxyurea influences adrenocortical function in humans. Eur. J. clin. Pharmacol., 54, 491-492
    • (1998) Eur. J. Clin. Pharmacol. , vol.54 , pp. 491-492
    • Navarra, P.1    Tringali, G.2    Preziosi, P.3
  • 132
    • 0022992615 scopus 로고
    • Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells
    • Nyce, J., Liu, L. & Jones, P.A. (1986) Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells. Nucleic Acids Res., 14, 4353-4367
    • (1986) Nucleic Acids Res. , vol.14 , pp. 4353-4367
    • Nyce, J.1    Liu, L.2    Jones, P.A.3
  • 133
    • 0344267743 scopus 로고    scopus 로고
    • Development of acute promyelocytic leukemia with isochromosome 17q after BCR/ABL positive chronic myeloid leukemia
    • Ören, H., Düzovali, O., Yüksel, E., Sakizli, M. & Irken, G. (1999) Development of acute promyelocytic leukemia with isochromosome 17q after BCR/ABL positive chronic myeloid leukemia. Cancer Genet. Cytogenet., 109, 141-143
    • (1999) Cancer Genet. Cytogenet. , vol.109 , pp. 141-143
    • Ören, H.1    Düzovali, O.2    Yüksel, E.3    Sakizli, M.4    Irken, G.5
  • 134
    • 0014219895 scopus 로고
    • Radiobiology. Repair replication in Hela cells after large doses of X-irradiation
    • Painter, R.B. & Cleaver, J.E. (1967) Radiobiology. Repair replication in HeLa cells after large doses of X-irradiation. Nature, 216, 369-370
    • (1967) Nature , vol.216 , pp. 369-370
    • Painter, R.B.1    Cleaver, J.E.2
  • 137
    • 0021707283 scopus 로고
    • Enhancement of induced sister chromatid exchange and chromosomal aberrations by inhibitors of DNA repair processes
    • Palitti, F., Tanzarella, C., Degrassi, F., De Salvia, R. & Fiore, M. (1984a) Enhancement of induced sister chromatid exchange and chromosomal aberrations by inhibitors of DNA repair processes. Toxicol. Pathol., 12, 269-273
    • (1984) Toxicol. Pathol. , vol.12 , pp. 269-273
    • Palitti, F.1    Tanzarella, C.2    Degrassi, F.3    De Salvia, R.4    Fiore, M.5
  • 138
    • 0021667632 scopus 로고
    • Potentiation of induced sister chromatid exchanges and chromatid-type aberrations by inhibitors of DNA synthesis and repair in G2
    • Palitti, F., Degrassi, F., De Salvia, R., Tanzarella, C. & Fiore, M. (1984b) Potentiation of induced sister chromatid exchanges and chromatid-type aberrations by inhibitors of DNA synthesis and repair in G2. Basic Life Sci., 29A, 313-318
    • (1984) Basic Life Sci. , vol.29 A , pp. 313-318
    • Palitti, F.1    Degrassi, F.2    De Salvia, R.3    Tanzarella, C.4    Fiore, M.5
  • 139
    • 0025739951 scopus 로고
    • Use of hydroxyurea in chronic myeloid leukemia during pregnancy: A case report
    • Patel, M., Dukes, I.A.F. & Hull, J.D. (1991) Use of hydroxyurea in chronic myeloid leukemia during pregnancy: A case report. Am. J. Obstet. Gynecol., 165, 565-566
    • (1991) Am. J. Obstet. Gynecol. , vol.165 , pp. 565-566
    • Patel, M.1    Dukes, I.A.F.2    Hull, J.D.3
  • 141
    • 0017656182 scopus 로고
    • Sister chromatid exchange and chromosome aberration analysis with the use of several carcinogens and noncarcinogens
    • Popescu, N.C., Turnbull, D. & DiPaolo, J.A. (1977) Sister chromatid exchange and chromosome aberration analysis with the use of several carcinogens and noncarcinogens. J. natl Cancer Inst., 59, 289-293
    • (1977) J. Natl Cancer Inst. , vol.59 , pp. 289-293
    • Popescu, N.C.1    Turnbull, D.2    DiPaolo, J.A.3
  • 145
    • 0014668437 scopus 로고
    • Does hydroxyurea inhibit chromosome repair in cultured human lymphocytes?
    • Prempree, T. & Merz, T. (1969) Does hydroxyurea inhibit chromosome repair in cultured human lymphocytes? Nature, 224, 603-604
    • (1969) Nature , vol.224 , pp. 603-604
    • Prempree, T.1    Merz, T.2
  • 149
    • 0024449308 scopus 로고
    • Skin lesions simulating chronic dermatomyositis during long-term hydroxyurea therapy
    • Richard, M., Truchetet, F., Friedel, J., Leclech, C. & Heid, E. (1989) Skin lesions simulating chronic dermatomyositis during long-term hydroxyurea therapy. J. Am. Acad. Dermatol., 21, 797-799
    • (1989) J. Am. Acad. Dermatol. , vol.21 , pp. 797-799
    • Richard, M.1    Truchetet, F.2    Friedel, J.3    Leclech, C.4    Heid, E.5
  • 151
    • 0021956183 scopus 로고
    • DNA repair synthesis induced by N-hydroxyurea, acetohydroxamic acid, and N-hydroxyurethane in primary rat hepatocyte cultures: Comparative evaluation using the autoradiographic and the bromodeoxyuridine density-shift method
    • Rossberger, S. & Andrae, U. (1985) DNA repair synthesis induced by N-hydroxyurea, acetohydroxamic acid, and N-hydroxyurethane in primary rat hepatocyte cultures: Comparative evaluation using the autoradiographic and the bromodeoxyuridine density-shift method. Mutat. Res., 145, 201-207
    • (1985) Mutat. Res. , vol.145 , pp. 201-207
    • Rossberger, S.1    Andrae, U.2
  • 152
    • 0003594289 scopus 로고    scopus 로고
    • Frankfurt, Rote Liste Service GmbH
    • Rote Liste Sekretariat (1998) Rote Liste 1998, Frankfurt, Rote Liste Service GmbH, pp. 86-106, 86-115
    • (1998) Rote Liste 1998 , pp. 86-106
  • 153
    • 0342623128 scopus 로고    scopus 로고
    • London, The Pharmaceutical Press [MicroMedex Online: Health Care Series]
    • Royal Pharmaceutical Society of Great Britain (1999) Martindale, The Extra Pharmacopoeia, 13th Ed., London, The Pharmaceutical Press [MicroMedex Online: Health Care Series]
    • (1999) Martindale, The Extra Pharmacopoeia, 13th Ed.
  • 156
    • 0031443344 scopus 로고    scopus 로고
    • Nitric oxide generation from hydroxyurea via copper-catalyzed peroxidation and implications for pharmacological actions of hydroxyurea
    • Sato, K., Akaike, T., Sawa, T., Miyamoto, Y., Suga, M., Ando, M. & Maeda, H. (1997) Nitric oxide generation from hydroxyurea via copper-catalyzed peroxidation and implications for pharmacological actions of hydroxyurea. Jpn. J. Cancer Res., 88, 1199-1204
    • (1997) Jpn. J. Cancer Res. , vol.88 , pp. 1199-1204
    • Sato, K.1    Akaike, T.2    Sawa, T.3    Miyamoto, Y.4    Suga, M.5    Ando, M.6    Maeda, H.7
  • 157
    • 0031002235 scopus 로고    scopus 로고
    • Hydroxyurea for treatment of unresectable and recurrent meningiomas. II. Decrease in the size of meningiomas in patients treated with hydroxyurea
    • Schrell, U.M., Rittig, M.G., Anders, M., Koch, U.H., Marschalek, R., Kiesewetter, F. & Fahlbusch, R. (1997) Hydroxyurea for treatment of unresectable and recurrent meningiomas. II. Decrease in the size of meningiomas in patients treated with hydroxyurea. J. Neurosurg., 86, 840-844
    • (1997) J. Neurosurg. , vol.86 , pp. 840-844
    • Schrell, U.M.1    Rittig, M.G.2    Anders, M.3    Koch, U.H.4    Marschalek, R.5    Kiesewetter, F.6    Fahlbusch, R.7
  • 158
    • 0015135814 scopus 로고
    • DNA synthesis inhibition and cell death associated with hydroxyurea teratogenesis in rat embryos
    • Scott, W.J., Ritter, E.J. & Wilson, J.G. (1971) DNA synthesis inhibition and cell death associated with hydroxyurea teratogenesis in rat embryos. Dev. Biol., 26, 306-315
    • (1971) Dev. Biol. , vol.26 , pp. 306-315
    • Scott, W.J.1    Ritter, E.J.2    Wilson, J.G.3
  • 159
    • 0029982591 scopus 로고    scopus 로고
    • Hydroxyurea therapy in children severely affected with sickle cell disease
    • Scott, J.P., Hillery, C.A., Brown, E.R., Misiewicz, V. & Labotka, R.J. (1996) Hydroxyurea therapy in children severely affected with sickle cell disease. J. Pediatr., 128, 820-828
    • (1996) J. Pediatr. , vol.128 , pp. 820-828
    • Scott, J.P.1    Hillery, C.A.2    Brown, E.R.3    Misiewicz, V.4    Labotka, R.J.5
  • 160
    • 0022573722 scopus 로고
    • Treatment of polycythemia vera with hydroxyurea
    • Sharon, R., Tatarsky, I. & Ben-Arieh, Y. (1986) Treatment of polycythemia vera with hydroxyurea. Cancer, 57, 718-720
    • (1986) Cancer , vol.57 , pp. 718-720
    • Sharon, R.1    Tatarsky, I.2    Ben-Arieh, Y.3
  • 161
    • 0017286171 scopus 로고
    • Recombination and hydroxyurea inhibition of DNA synthesis in yeast meiosis
    • Simchen, G., Idar, D. & Kassir, Y. (1976) Recombination and hydroxyurea inhibition of DNA synthesis in yeast meiosis. Mol. Gen. Genet., 144, 21-27
    • (1976) Mol. Gen. Genet. , vol.144 , pp. 21-27
    • Simchen, G.1    Idar, D.2    Kassir, Y.3
  • 162
    • 0030791371 scopus 로고    scopus 로고
    • No therapeutic advantage from didanosine (ddI) and hydroxyurea versus ddi alone in patients with HIV infection
    • Simonelli, C., Comar, M., Zanussi, S., De Paoli, P., Tirelli, U. & Giacca, M. (1997) No therapeutic advantage from didanosine (ddI) and hydroxyurea versus ddI alone in patients with HIV infection. AIDS, 11, 1299-1300
    • (1997) AIDS , vol.11 , pp. 1299-1300
    • Simonelli, C.1    Comar, M.2    Zanussi, S.3    De Paoli, P.4    Tirelli, U.5    Giacca, M.6
  • 163
    • 0026742822 scopus 로고
    • Hydroxyurea-induced cell death in human T lymphoma cells as related to imbalance in DNA/protein cycle and deoxyribonucleotide pools and DNA strand breaks
    • Skog, S., Heiden, T., Eriksson, S., Wallström, B. & Tribukait, B. (1992) Hydroxyurea-induced cell death in human T lymphoma cells as related to imbalance in DNA/protein cycle and deoxyribonucleotide pools and DNA strand breaks. Anticancer Drugs, 3, 379-386
    • (1992) Anticancer Drugs , vol.3 , pp. 379-386
    • Skog, S.1    Heiden, T.2    Eriksson, S.3    Wallström, B.4    Tribukait, B.5
  • 164
    • 8944224535 scopus 로고    scopus 로고
    • Detection of in vitro clastogens and spindle poisons by the mouse lymphoma assay using the microwell method: Interim report of an international collaborative study
    • Sofuni, T., Honma, M., Hayashi, M., Shimada, H., Tanaka, N., Wakuri, S., Awogi, T., Yamamoto, K.I, Nishi, Y. & Nakadate, M. (1996) Detection of in vitro clastogens and spindle poisons by the mouse lymphoma assay using the microwell method: Interim report of an international collaborative study. Mutagenesis, 11, 349-355
    • (1996) Mutagenesis , vol.11 , pp. 349-355
    • Sofuni, T.1    Honma, M.2    Hayashi, M.3    Shimada, H.4    Tanaka, N.5    Wakuri, S.6    Awogi, T.7    Yamamoto, K.I.8    Nishi, Y.9    Nakadate, M.10
  • 166
    • 0026704782 scopus 로고
    • Experience with hydroxyurea as a radiosensitizer in carcinoma of the cervix
    • Stehman, F.B. (1992) Experience with hydroxyurea as a radiosensitizer in carcinoma of the cervix. Semin. Oncol., 19, 48-52
    • (1992) Semin. Oncol. , vol.19 , pp. 48-52
    • Stehman, F.B.1
  • 167
    • 0031214203 scopus 로고    scopus 로고
    • Hydroxyurea, 5-fluorouracil infusion, and cisplatin adjunct to radiation therapy in cervical carcinoma: A phase I-II trial of the Gynecologic Oncology Group
    • Stehman, F.B., Bundy, B.N., Kucera, P.R., Deppe, G., Reddy, S. & O'Connor, D.M. (1997) Hydroxyurea, 5-fluorouracil infusion, and cisplatin adjunct to radiation therapy in cervical carcinoma: A phase I-II trial of the Gynecologic Oncology Group. Gynecol. Oncol., 66, 262-267
    • (1997) Gynecol. Oncol. , vol.66 , pp. 262-267
    • Stehman, F.B.1    Bundy, B.N.2    Kucera, P.R.3    Deppe, G.4    Reddy, S.5    O'Connor, D.M.6
  • 168
    • 0031982894 scopus 로고    scopus 로고
    • Acute myeloid leukemia and myelodysplastic syndromes following essential thrombocythemia treated with hydroxyurea: High proportion of cases with 17p deletion
    • Sterkers, Y., Preudhomme, C., Laï, J.-L., Demory, J.-L., Caulier, M.-T., Wattel, E., Borderssoule, D., Bauters, F. & Fenaux, P. (1998) Acute myeloid leukemia and myelodysplastic syndromes following essential thrombocythemia treated with hydroxyurea: High proportion of cases with 17p deletion. Blood, 91, 616-622
    • (1998) Blood , vol.91 , pp. 616-622
    • Sterkers, Y.1    Preudhomme, C.2    Laï, J.-L.3    Demory, J.-L.4    Caulier, M.-T.5    Wattel, E.6    Borderssoule, D.7    Bauters, F.8    Fenaux, P.9
  • 170
    • 0342623127 scopus 로고    scopus 로고
    • Stuttgart, Medpharm Scientific Publishers [MicroMedex Online: Health Care Series]
    • Swiss Pharmaceutical Society, ed. (1999) Index Nominum, International Drug Directory, 16th Ed., Stuttgart, Medpharm Scientific Publishers [MicroMedex Online: Health Care Series]
    • (1999) Index Nominum, International Drug Directory, 16th Ed.
  • 172
    • 0030859996 scopus 로고    scopus 로고
    • Achievement of a complete cytogenetic response with hydroxyurea in a patient with chronic myelogenous leukemia
    • Tanaka, M., Yamazaki, Y., Kondo, E., Hattori, M., Tsushita, K. & Utsumi, M. (1997) Achievement of a complete cytogenetic response with hydroxyurea in a patient with chronic myelogenous leukemia. Leuk. Res., 21, 465-468
    • (1997) Leuk. Res. , vol.21 , pp. 465-468
    • Tanaka, M.1    Yamazaki, Y.2    Kondo, E.3    Hattori, M.4    Tsushita, K.5    Utsumi, M.6
  • 173
    • 0032529679 scopus 로고    scopus 로고
    • Is hydroxyurea leukemagenic in essential thrombocythemia?
    • discussion 1460-1461
    • Tefferi, A. (1998) Is hydroxyurea leukemagenic in essential thrombocythemia? (Letter to the Editor). Blood, 92, 1459-1460; discussion 1460-1461
    • (1998) Blood , vol.92 , pp. 1459-1460
    • Tefferi, A.1
  • 175
    • 0015832752 scopus 로고
    • Teratogenicity of hydroxyurea in rhesus monkeys
    • Theisen, C.T., Fradkin, R. & Wilson, J.G. (1973) Teratogenicity of hydroxyurea in rhesus monkeys. Teratology, 7, A29
    • (1973) Teratology , vol.7
    • Theisen, C.T.1    Fradkin, R.2    Wilson, J.G.3
  • 177
    • 0016729499 scopus 로고
    • Hydroxyurea
    • Timson, J. (1975) Hydroxyurea. Mutat. Res., 32, 115-132
    • (1975) Mutat. Res. , vol.32 , pp. 115-132
    • Timson, J.1
  • 178
    • 0025338571 scopus 로고
    • Hypoxanthine enhances hydroxyurea-induced sister-chromatid exchanges in Chinese hamster ovary cells
    • Tohda, H. & Oikawa, A. (1990) Hypoxanthine enhances hydroxyurea-induced sister-chromatid exchanges in Chinese hamster ovary cells. Mutat. Res., 230, 235-240
    • (1990) Mutat. Res. , vol.230 , pp. 235-240
    • Tohda, H.1    Oikawa, A.2
  • 181
    • 0018413125 scopus 로고
    • Morphological transformation, DNA damage, and chromosomal aberrations induced by a direct DNA perturbation of synchronized Syrian hamster embryo cells
    • Tsutsui, T., Barrett, J.C. & Ts'o, P.O.P. (1979) Morphological transformation, DNA damage, and chromosomal aberrations induced by a direct DNA perturbation of synchronized Syrian hamster embryo cells. Cancer Res., 39, 2356-2365
    • (1979) Cancer Res. , vol.39 , pp. 2356-2365
    • Tsutsui, T.1    Barrett, J.C.2    Ts'o, P.O.P.3
  • 185
    • 0031803081 scopus 로고    scopus 로고
    • Chronic hydroxyurea-induced dermatomyositis-like eruption with severe dermal elastosis
    • Velez, A., Lopez-Rubio, F. & Moreno, J.C. (1998) Chronic hydroxyurea-induced dermatomyositis-like eruption with severe dermal elastosis. Clin. exp. Dermatol., 23, 94-95
    • (1998) Clin. Exp. Dermatol. , vol.23 , pp. 94-95
    • Velez, A.1    Lopez-Rubio, F.2    Moreno, J.C.3
  • 186
    • 0030771289 scopus 로고    scopus 로고
    • Absence of viral rebound after treatment of HIV-infected patients with didanosine and hydroxycarbamide
    • Vila, J., Nugier, F., Bargues, G., Vallet, T., Peyramond, D., Hamedi-Sangsari, F. & Seigneurin, J.M. (1997) Absence of viral rebound after treatment of HIV-infected patients with didanosine and hydroxycarbamide. Lancet, 350, 635-636
    • (1997) Lancet , vol.350 , pp. 635-636
    • Vila, J.1    Nugier, F.2    Bargues, G.3    Vallet, T.4    Peyramond, D.5    Hamedi-Sangsari, F.6    Seigneurin, J.M.7
  • 187
    • 0029923839 scopus 로고    scopus 로고
    • Pharmacokinetics of hydroxyurea in patients infected with human immunodeficiency virus type I
    • Villani, P., Maserati, R., Regazzi, M.B., Giacchino, R. & Lori, F. (1996) Pharmacokinetics of hydroxyurea in patients infected with human immunodeficiency virus type I. J. clin. Pharmacol., 36, 117-121
    • (1996) J. Clin. Pharmacol. , vol.36 , pp. 117-121
    • Villani, P.1    Maserati, R.2    Regazzi, M.B.3    Giacchino, R.4    Lori, F.5
  • 188
    • 0018667261 scopus 로고
    • A developmental test battery for neurobehavioral toxicity in rats: A preliminary analysis using monosodium glutamate calcium carrageenan, and hydroxyurea
    • Vorhees, C.V., Butcher, R.E., Brunner, R.L. & Sobotka, T.J. (1979) A developmental test battery for neurobehavioral toxicity in rats: A preliminary analysis using monosodium glutamate calcium carrageenan, and hydroxyurea. Toxicol. appl. Pharmacol., 50, 267-282
    • (1979) Toxicol. Appl. Pharmacol. , vol.50 , pp. 267-282
    • Vorhees, C.V.1    Butcher, R.E.2    Brunner, R.L.3    Sobotka, T.J.4
  • 189
    • 0020610868 scopus 로고
    • Developmental toxicity of phychotoxicity of FD and C red dye no. 40 (allura red AC) in rats
    • Vorhees, C.V., Butcher, R.E., Brunner, R.L., Wootten, V. & Sobotka, T.J. (1983) Developmental toxicity of phychotoxicity of FD and C red dye No. 40 (allura red AC) in rats. Toxicology, 28, 207-217
    • (1983) Toxicology , vol.28 , pp. 207-217
    • Vorhees, C.V.1    Butcher, R.E.2    Brunner, R.L.3    Wootten, V.4    Sobotka, T.J.5
  • 190
    • 0028956292 scopus 로고
    • Clinical and laboratory effects of long-term administration of hydroxyurea to patients with sickle-cell/beta-thalassaemia
    • Voskaridou, E., Kalotychou, V. & Loukopoulos, D. (1995) Clinical and laboratory effects of long-term administration of hydroxyurea to patients with sickle-cell/beta-thalassaemia. Br. J. Haematol., 89, 479-484
    • (1995) Br. J. Haematol. , vol.89 , pp. 479-484
    • Voskaridou, E.1    Kalotychou, V.2    Loukopoulos, D.3
  • 191
    • 0029680548 scopus 로고    scopus 로고
    • Phase I trial of high-dose infusional hydroxyurea, high-dose infusional 5-fluorouracil and recombinant interferon-alpha-2a in patients with advanced malignancies
    • Wadler, S., Haynes, H., Schechner, R., Rozenblit, A. & Wiernik, P.H. (1996) Phase I trial of high-dose infusional hydroxyurea, high-dose infusional 5-fluorouracil and recombinant interferon-alpha-2a in patients with advanced malignancies. Invest. New Drugs, 13, 315-320
    • (1996) Invest. New Drugs , vol.13 , pp. 315-320
    • Wadler, S.1    Haynes, H.2    Schechner, R.3    Rozenblit, A.4    Wiernik, P.H.5
  • 192
    • 0023930086 scopus 로고
    • Mouse lymphoma L5178Y thymidine kinase locus assay of 50 compounds
    • Wangenheim, J. & Bolcsfoldi, G. (1988) Mouse lymphoma L5178Y thymidine kinase locus assay of 50 compounds. Mutagenesis, 3, 193-205
    • (1988) Mutagenesis , vol.3 , pp. 193-205
    • Wangenheim, J.1    Bolcsfoldi, G.2
  • 193
    • 0021036484 scopus 로고
    • A comparison of the in vivo and in vitro response of mammalian embryos to a teratogenic insult
    • Warner, C. W., Sadler, T. W., Shockey, J. & Smith, M.K. (1983) A comparison of the in vivo and in vitro response of mammalian embryos to a teratogenic insult. Toxicology, 28, 271-282
    • (1983) Toxicology , vol.28 , pp. 271-282
    • Warner, C.W.1    Sadler, T.W.2    Shockey, J.3    Smith, M.K.4
  • 194
    • 0028276190 scopus 로고
    • Acute leukaemia after hydroxyurea therapy in polycythemia vera and allied disorders: Prospective study of efficacy and leukaemogenicity with therapeutic implications
    • Weinfeld, A., Swolin, B. & Westin, J. (1994) Acute leukaemia after hydroxyurea therapy in polycythemia vera and allied disorders: Prospective study of efficacy and leukaemogenicity with therapeutic implications. Eur. J. Haematol., 52, 134-139
    • (1994) Eur. J. Haematol. , vol.52 , pp. 134-139
    • Weinfeld, A.1    Swolin, B.2    Westin, J.3
  • 196
    • 0023279929 scopus 로고
    • Hydroxyurea in the treatment of polycythemia vera: A prospective study of 100 patients over a 20-year period
    • West, W.O. (1987) Hydroxyurea in the treatment of polycythemia vera: A prospective study of 100 patients over a 20-year period. South. med. J., 80, 323-327
    • (1987) South. Med. J. , vol.80 , pp. 323-327
    • West, W.O.1
  • 197
    • 0029105299 scopus 로고
    • Effects of acetaminophen and hydroxyurea on spermatogenesis and sperm chromatin structure in laboratory mice
    • Wiger, R., Hongslo, J.K., Evenson, D.P., De Angelis, P., Schwartze, P.E. & Holme, J.A. (1995) Effects of acetaminophen and hydroxyurea on spermatogenesis and sperm chromatin structure in laboratory mice. Reprod. Toxicol., 9, 21-33
    • (1995) Reprod. Toxicol. , vol.9 , pp. 21-33
    • Wiger, R.1    Hongslo, J.K.2    Evenson, D.P.3    De Angelis, P.4    Schwartze, P.E.5    Holme, J.A.6
  • 198
    • 0343471843 scopus 로고
    • Teratogenic causation in man and its evaluation in non-human primates
    • Motulsky, A.G. & Lenz, W., eds, Amsterdam, Excerpta Medica
    • Wilson, J.G. (1974) Teratogenic causation in man and its evaluation in non-human primates. In: Motulsky, A.G. & Lenz, W., eds, Birth Defects. Proceedings of 4th International Conference, Amsterdam, Excerpta Medica, pp. 191-203
    • (1974) Birth Defects. Proceedings of 4th International Conference , pp. 191-203
    • Wilson, J.G.1
  • 199
    • 0016492795 scopus 로고
    • Comparative distribution and embryotoxicity of hydroxyurea in pregnant rats and rhesus monkeys
    • Wilson, J.G., Scott, W.J., Ritter, E.J. & Fradkin, R. (1975) Comparative distribution and embryotoxicity of hydroxyurea in pregnant rats and rhesus monkeys. Teratology, 11, 169-178
    • (1975) Teratology , vol.11 , pp. 169-178
    • Wilson, J.G.1    Scott, W.J.2    Ritter, E.J.3    Fradkin, R.4
  • 200
    • 0020531394 scopus 로고
    • Induction of mitotic recombination by UV and diepoxybutane and its enhancement by hydroxyurea in Saccharomyces cerevisiae
    • Zaborowska, D., Swietlinska, Z. & Zuk, J. (1983) Induction of mitotic recombination by UV and diepoxybutane and its enhancement by hydroxyurea in Saccharomyces cerevisiae. Mutat. Res., 120, 21-26
    • (1983) Mutat. Res. , vol.120 , pp. 21-26
    • Zaborowska, D.1    Swietlinska, Z.2    Zuk, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.