Hydroxyurea-related ankle ulcers in patients with myeloproliferative disorders: A case report and review of the literature

Annals of Plastic Surgery

Volumn 39, Issue 5, 1997, Pages 546-549

  Cox, Christopher ^a   Nowicky, David ^a   Young, Rod ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOPURINOL; AMITRIPTYLINE; DIGOXIN; FUROSEMIDE; HYDROXYUREA; LEVOTHYROXINE; OMEPRAZOLE; PENTOXIFYLLINE;

ADULT; ANKLE; ARTICLE; CANCER CHEMOTHERAPY; CASE REPORT; CHRONIC MYELOID LEUKEMIA; DISEASE ASSOCIATION; HUMAN; MALE; MYELOPROLIFERATIVE DISORDER; PRIORITY JOURNAL; SKIN TRANSPLANTATION; SKIN ULCER; SPLIT THICKNESS SKIN GRAFT;

EID: 0030729450     PISSN: 01487043     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000637-199711000-00017     Document Type: Article

References (11)

1. Sinclair WK, Hydroxyurea : differential lethal effects on cultured mammalian cells during the cell cycle. Science 1965;150:1729-1731
2. Donehower RC, Hydroxyurea. In: Chabner BA, Longo DL, eds. Cancer chemotherapy. 2nd ed. Philadelphia: JB Lippincott, 1996:253-261
3. Thelander L, Reichard P. Reduction of ribonudeotides. Annu Rev Biochein 1979;48:133-158
4. Plucinski TM, Fager RS, Reddy GPV. Allosteric interaction of components of the complex is responsible for enzyme cross-inhibition. Mol Pharmacol 1990;38:114-120
5. Kennedy BJ, Smith LR, Goltz RW. Skin changes second- ary to hydroxyurea therapy. Arch Dermatol 1972;111: 183-187
6. Renfro L, Kamiao H, Raphael B, et al. Ulcerative lichen. planu-like dermatitis associated with hydraxyurea. J Am Acad Dermatol 1991;24:143-145
7. Montefusco I, Alimena G, Gastaldi R, et al. Unusual derlmatologic toxicity of long term therapy with hydroxyin chronic myelogenous leukemia. Tumori 1986;72: 317-321
8. Nguyen TV, Margolis DJ, Hydraxyutea and lower leg ulcers. Cutis 1993;52:217-219
9. Iwama H, Kawakubo K, Nehashi Y, et al. [A lower-leg ulcer during therapy for essential thrombocythemia]. Gan To Kagaku Ryoho 1996;23(7):937-939
10. Masuoka H, Kobayashi M, Kaito K, et al. [Bilateral ankle ulcers with hydrooxyurea therapy for chronic myelogenous leukemia]. Rinsho Ketsueki 1995;36:156-158
11. Farber E, Baserga R. Differential effects of hydroxyurea on survival of proliferating cells in vivo. Cancer Res 1969;20: 136-139