Role of the M2 subunit of ribonucleotide reductase in regulation by hydroxyurea of the activity of the anti-HIV-1 agent 2',3'-dideoxyinosine

Biochemical Pharmacology

Volumn 56, Issue 1, 1998, Pages 105-112

  Gao, Wen Yi ^a,c   Zhou, Bing Sen ^b   Johns, David G ^a   Mitsuya, Hiroaki ^a   Yen, Yun ^b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Antiviral drugs; Combination therapy; Dideoxynucleosides; Drug resistance; HIV 1 mutants; HIV 1 replication

Indexed keywords

DIDANOSINE; HYDROXYUREA; MESSENGER RNA; RIBONUCLEOTIDE REDUCTASE;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG POTENTIATION; DRUG RESISTANCE; ENZYME SUBUNIT; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; VIRUS REPLICATION;

ANTI-HIV AGENTS; BASE SEQUENCE; CELL CYCLE; CELL DIVISION; CELL LINE; DIDANOSINE; DNA PRIMERS; DNA REPLICATION; DRUG SYNERGISM; ENZYME INHIBITORS; HUMANS; HYDROXYUREA; REVERSE TRANSCRIPTASE INHIBITORS; RIBONUCLEOTIDE REDUCTASES; RNA, MESSENGER;

EID: 0031721513     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00127-0     Document Type: Article

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