Recombinant human adenovirus with rat MIP-2 gene insertion causes prolonged PMN recruitment to the murine brain

European Journal of Neuroscience

Volumn 8, Issue 9, 1996, Pages 1803-1811

  Bell, M D ^a   Taub, D D ^b   Kunkel, S J ^c   Strieter, R M ^c   Foley, R ^d   Gauldie, J ^d   Perry, V H ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b SAIC FREDERICK INC   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d MCMASTER UNIVERSITY   (Canada)

Author keywords

Blood brain barrier; Chemokines; Inflammation; Tachyphylaxis

Indexed keywords

BETA GALACTOSIDASE; CHEMOATTRACTANT; MACROPHAGE INFLAMMATORY PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CELL TYPE; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DEMYELINATION; EXPRESSION VECTOR; FOAM CELL; GENE INSERTION; HUMAN ADENOVIRUS; INFLAMMATION; LEUKOCYTE; MACROPHAGE; MOUSE; NERVE CELL DEGENERATION; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS; TACHYPHYLAXIS; TRANSGENE; VIRUS RECOMBINANT; VIRUS REPLICATION;

EID: 0029784344     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1996.tb01324.x     Document Type: Article

References (23)

1. Addison, C. L., Braciak, T., Ralston, R., Muller, W. J., Gauldie, J. and Graham, F. L. (1995) Intra-tumoral injection of an adenovirus expressing interleukin-2 induces regression and immunity in a murine breast cancer model. Proc. NatI Acad. Sci. USA, in press.
2. Akli, S., Caillaud, C., Vigne, E., Stratford-Perricaudet, L. D., Poenaru, L., Perricaudet, M., Kahn, A. and Peschanski, M. R. (1993) Transfer of a foreign gene into the brain using adenovirus vectors. Nature Genet., 3, 224-228.
3. Andersson, P. B., Perry, V. H. and Gordon, S. (1991) The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration. Neuroscience, 42, 201-214.
4. Andersson, P. B., Perry, V. H. and Gordon, S. (1992a) The acute inflammatory response to lipopolysaccharide in CNS parenchyma differs from that in other body tissues. Neuroscience, 48, 169-186.
5. Andersson, P. B., Perry, V. H. and Gordon, S. (1992b) Intracerebral injection of proinflammatory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system. J. Exp. Med., 176, 255-259.
6. Austyn, J. M. and Gordon, S. (1981) F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur. J. Immimol., 11, 805-815.
7. Bajocchi, G., Feldman, S. H., Crystal, R. G. and Mastrangeli, A. (1993) Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors. Nature Genet., 3, 229-234.
8. Baumgarten, A., Melrose, G. J. H. and Vagg, W. J. (1970) Interactions between histamine and bradykinin assessed by continuous recording of increased vascular permeability. J. Physiol. (Land.), 208, 669-675.
9. Bhattacharya, A., Dorf, M. E. and Springer, T. A. (1981) A shared alloantigenic determinant on I-A and I-E subregions: evidence for I region gene duplication. J. Immunol., 127, 2488-2495.
10. Braciak, T. A., Mittal, S. K., Graham, F. L., Richards, C. D. and Gauldie, J. (1993) Construction of recombinant human type-5 adenoviruses expressing rodent IL-6 genes - an approach to investigate in vivo cytokine function. J. Immunol., 151, 5145-5153.
11. Byrnes, A. P., Rusby, J. E., Wood, M. J. A. and Charlton, H. M. (1995) Adenovirus gene transfer causes inflammation in the brain. Neuroscience, 66, 1015-1024.
12. Cobbold, S. P., Jayasuriya, A., Nash, A., Prospero, T. D. and Waldmann, H. (1984) Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo. Nature, 312, 548-551.
13. Colditz, I. G. (1991) Desensitisation mechanisms regulating plasma leakage and neutrophil emigration. In Gordon, J. (ed.), Vascular Endothelium: Interactions with Circulating Cells. Elsevier Science Publishers, Amsterdam, pp. 175-187.
14. Jaffe, H. A, Danel, C., Longenecker, G., Metzger, M., Setogucni, Y., Rosenfeld, M. A., Gant, T. W., Thorgeirsson, S. S., Stralford-Perricaudet, L. D. and Perricaudet, M. (1992) Adenovirus-mediated in vivo gene transfer and expression in normal rat liver. Nature Genet., 1, 372-378.
15. Kass-Eisler, A., Falck-Pedersen, E., Elfenbeim, D. H., Alvira, M., Buttrick, P. M. and Leinwand, L. A. (1994) The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer. Gene Therapy, 1, 395-402.
16. Kochanek, P. M. and Hallenbeck, J. M. (1992 Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke. Stroke, 23, 1367-1379.
17. Le Gal La Salle, G., Robert, J. J., Berrard, S., Ridoux, V., Stratford-Perricaudet, L. D., Perricaudet, M. and Mallet, J. (1993) An adenovirus vector for gene transfer into neurons and glia in the brain. Science, 259, 988-990.
18. Lemarchand, P., Jaffe, H. A., Danel, C., Cid, M. C., Kleinman, H. K., Stratford-Perricaudet, L. D., Perricaudet, M., Pavirani, A., Lecocq, J. and Crystal, R. G. (1992) Adenovirus-mediated transfer of a recombinant human a1-antitrypsin cDNA to human endothelial cells. Proc. Natl Acad. Sci. USA, 89, 6482-6488.
19. Lewis, T. and Grant, R. T. (1924) Vascular reactions of the skin to injury. Blood, 11, 209-265.
20. Locksley, R. M., Wilson, C. B. and Klebanoff, S. J. (1983) Increased respiratory burst in myeloperoxidase-deficient monocytes. Blood, 62, 902-909.
21. Lucas, N. W., Strieter, R. M., Standiford, T. J. and Kunkel, S. J. (1995) Characterisation of chemokine function in animal models of disease. Immunomethods, in press.
22. McGeer, P. L., Walker, D. G., Akiyama, H., Yasuhara, O. and McGeer, E. G. (1994) Involvement of microglia in Alzheimer's disease. Neuropathol. Appl. Neurobiol., 20, 191-192.
23. McLean, I. W. and Nakane, P. K. (1974) Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy. J. Histochem. Cytochem., 22, 1077-1083.