Sulfonamide resistance: Mechanisms and trends

Drug Resistance Updates

Volumn 3, Issue 3, 2000, Pages 155-160

  Sköld, Ola ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBENZOIC ACID; DIHYDROPTEROATE SYNTHASE; FOLIC ACID; SULFONAMIDE;

BACTERIAL INFECTION; CAMPYLOBACTER; DRUG BINDING; DRUG SELECTIVITY; ESCHERICHIA COLI; GENE MUTATION; GENE SEQUENCE; MYCOBACTERIUM LEPRAE; NEISSERIA MENINGITIDIS; NONHUMAN; PNEUMOCYSTIS CARINII; PRIORITY JOURNAL; SHORT SURVEY; STAPHYLOCOCCUS; STREPTOCOCCUS PNEUMONIAE;

EID: 0033853659     PISSN: 13687646     EISSN: None     Source Type: Journal    
DOI: 10.1054/drup.2000.0146     Document Type: Article

References (42)

1. Ein beitrag zur chemotherapie der bakteriellen infektionen
2. Trimethoprim-sulfamethoxazole-associated blood dyscrasias Ten years experience of the Swedish spontaneous reporting system
3. Drug-related blood dyscrasias in a Swedish reporting system, 1985-1994
4. The relation of ρ-aminobenzoic acid to the mechanism of the action of sulphanilamide
5. The biosynthesis of folic acid II. Inhibition by sulfonamides
6. Characterization of mutationally altered dihydropteroate synthase and its ability to form a sulfonamide-containing dihydrofolate analog
7. The characteristics and significance of sulfonamides as substrates for Escherichio coli dihydropteroate synthase
8. Mechanisms of resistance of Escherichia coli to sulfonamides
9. R-Factor-Mediated Resistance to sulfonamides by a plasmid-borne, drug-resistant dihydropteroate synthase
10. Cloning, sequencing, and enhanced expression of the dihydropteroate synthase gene of Escherichia coli MC 4100
11. Characterization of a mutationally altered dihydropteroate synthase contributing to sulfathiazole resistance in Escherichia coli
12. Point mutations in the dihydropteroate synthase gene causing sulfonamide resistance
13. Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase
14. Functional cloning of the dihydropteroate synthase gene of Staphylococcus haemolyticus
15. Structure and function of the dihydropteroate synthase from Staphylococcus aureus
16. The multifunctional folic acid synthesis fas gene of Pneumocystis carinii encodes dihydroneopterin aldolase, hydroxymethyldihydropterin pyrophosphokinase and dihydropteroate synthase
17. Dihydropteroate synthase polymorphisms in Pneumocystis carinii
18. Failure of cotrimoxazole in Pneumocystis carinii infection and mutations in dihydropteroate synthase gene
19. Effects of mutations in Pneumocystis carinii dihydropteroate synthase gene on outcome of AIDS-associated P carinii pneumonia
20. High-Level Resistance to trimethoprim in clinical isolates of Campylobacter jejuni by acquisition of foreign genes (dfr 1 and dfr 9) expressing drug-insensitive dihydrofolate reductases
21. Sulfonamide resistance in clinical isolates of Campylobacter Jejuni: Mutational changes in the chromosomal dihydropteroate synthase
22. Sulfonamide resistance in Streptococcus pneumoniae: DNA sequence of the gene encoding dihydropteroate synthase and characterization of the enzyme
23. Mechanisms of sulfonamide resistance in clinical isolates of Streptococcus pneumoniae
24. Novel expansions of the gene encoding dihydropteroate synthase in trimethoprim-sulfamethoxazole-resistant Streptococcus pneumoniae
25. Insertions in dihydroptheroate synthase of Streptococcus pneumoniae are sufficient for development of sulfonamide resistance and lead to limited consequences for enzyme characteristics
26. Chemoprophylaxis and sulfonamide resistant streptococci
27. Sulfonamide resistance in Streptococcus pyogenes is associated with differences in the amino acid sequence of its chromosomal dihydropteroate synthase
28. Diaminodiphenylsulfone resistance in Mycobacterium leprae due to mutations in the dihydropteroate synthase gene
29. Transformational exchanges in the dihydropteroate synthase gene of Neisseria meningitidis: A novel mechanism for acquisition of sulfonamide resistance
30. Cloning and characterization of a DNA fragment that confers sulfonamide resistance in a Serogroup B, Serotype 15 Strain of Neisseria meningitidis
31. Sulfonamide resistance in Neisseria meningitidis as defined by site-directed mutagenesis could have its origin in other species
32. Adaptation to sulfonamide resistance in Neisseria meningitidis may have required compensatory changes to retain enzyme function: Kinetic analysis of dihydropteroate synthases from N. Meningitidis expressed in a knockout mutant of Escherichia coli
33. Additive effects of a two amino acid insertion and a single amino acid substitution in dihydropteroate synthase for the development of a sulfonamide resistant Neisseria meningitidis
34. Sulfonamide resistance mechanism in Escherichia coli R-plasmids can determine sulfonamide-resistant dihydropteroate synthases
35. R-factor-mediated resistance to sulfonamides by a plasmid-borne, drug-resistant dihydropteroate synthase
36. Plasmid-borne sulfonamide resistance determinants studied by restriction enzyme analysis
37. Site-specific recombination promotes linkage between trimethoprim- and sulfonamide-resistance genes. Sequence characterization of dfr 5 and sul 1 and a recombination active locus of Tn21
38. RSF1010 and a conjugative plasmid contain sul2, one of two known genes for plasmid-borne sulfonamide resistance dihydropteroate synthase
39. Molecular nature of a streptomycin and sulfonamide resistance plasmid (pBPI) prevalent in clinical Escherichia coli strains and integration of an ampicillin resistance transposon (TnA)
40. Genetic analyses of sulfonamide resistance and its dissemination in gram-negative bacteria illustrate new aspects of R plasmid evolution
41. On the mechanism of the development of multi-drug-resistant clones of Shigella