Adaptation to sulfonamide resistance in Neisseria meningitidis may have required compensatory changes to retain enzyme function: Kinetic analysis of dihydropteroate synthases from N. meningitidis expressed in a knockout mutant of Escherichia coli

Journal of Bacteriology

Volumn 179, Issue 3, 1997, Pages 831-837

  Fermér, Christian ^a   Swedberg, Göte ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DIHYDROPTEROATE SYNTHASE; DNA; ENZYME; LEUCINE; PHENYLALANINE; SULFONAMIDE;

ADAPTATION; ARTICLE; DRUG RESISTANCE; ENZYME ACTIVITY; ENZYME KINETICS; ESCHERICHIA COLI; GENE; MOLECULAR CLONING; NEISSERIA MENINGITIDIS; NONHUMAN; PHENOTYPE; PLASMID; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

EID: 0031035201     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.179.3.831-837.1997     Document Type: Article

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