Evidence for the involvement of two pathways in activation of extracellular signal-regulated kinase (Erk) and cell proliferation by Gi and Gq protein-coupled receptors in osteoblast-like cells

Journal of Bone and Mineral Research

Volumn 15, Issue 9, 2000, Pages 1697-1706

  Caverzasio, J ^a   Palmer, G ^a   Suzuki, A ^a   Bonjour, J P ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Lysophosphatidic acid; Mitogen activated protein kinase; Proliferation; Prostaglandin F(2 )

Indexed keywords

ADAPTOR PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; LYSOPHOSPHATIDIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN F2 ALPHA; RAS PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNOPRECIPITATION; MITOGENESIS; MOUSE; NONHUMAN; OSTEOBLAST; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

EID: 0033843748     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2000.15.9.1697     Document Type: Article

References (38)

1. Aluminum potentiates the effect of fluoride on tyrosine phosphorylation and osteoblast replication in vitro and bone mass in vivo
2. Mechanism of the mitogenic effect of fluoride on osteoblast-like cells: Evidences for a G protein-dependent tyrosine phosphorylation process
3. Fluoroaluminate induces pertussis toxin-sensitive protein phosphorylation: Differences in MC3T3-E1 osteoblastic and NIH3T3 fibroblastic cells
4. Mitogenic signaling via G protein-coupled receptors
5. Signaling from G-protein-coupled receptors to mitogen-activated protein (MAP)-kinase cascades
6. Cell growth control by G protein-coupled receptors: From signal transduction to signal integration
7. Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts
8. Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation
9. Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions
10. A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
11. Angiotensin II controls p21ras activity via pp60c-src
12. Role of c-Src tyrosine kinase in G protein-coupled receptor- and G beta gamma subunit-mediated activation of mitogen-activated protein kinases
13. Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors
14. Genetic evidence for a tyrosine kinase cascade preceding the mitogen-activated protein kinase cascade in vertebrate G protein signaling
15. Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells
16. Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway
17. Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
18. G beta gamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation
19. Gi-mediated activation of the Ras/MAP kinase pathway involves a 100 kDa tyrosine-phosphorylated Grb2 SH3 binding protein, but not Src nor Shc
20. Prostaglandin F2alpha stimulates tyrosine phosphorylation and mitogen-activated protein kinase in osteoblastic MC3T3-E1 cells via protein kinase C activation
21. Tyrosine kinases of the Src family participate in signaling to MAP kinase from both Gq and Gi-coupled receptors
22. Lysophosphatidic acid (LPA) is a potent mitogen for bone cells
23. Prostaglandin E1 and F2 alpha stimulate differentiation and proliferation, respectively, of clonal osteoblastic MC3T3-E1 cells by different second messengers in vitro
24. Activation of Src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts
25. G protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase. Shc adapter protein signaling complexes
26. Angiotensin II activates pp60c-src in vascular smooth muscle cells
27. Bombesin, bradykinin, vasopressin, and phorbol esters rapidly and transiently activate Src family tyrosine kinases in Swiss 3T3 cells. Dissociation from tyrosine phosphorylation of p125 focal adhesion kinase
28. The heterotrimeric Gq protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes
29. G protein-coupled receptors control vascular smooth muscle cell proliferation via pp60c-src and p21ras
30. Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase
31. Angiotensin II activates at least two tyrosine kinases in rat liver epithelial cells. Separation of the major calcium-regulated tyrosine kinase from p125FAK
32. Regulation of alkaline phosphatase activity by p38 MAP kinase in response to activation of Gi protein-coupled receptors by epinephrine in osteoblast-like cells
33. Fluoroaluminate induces activation and association of Src and Pyk2 tyrosine kinases in osteoblastic MC3T3-E1 cells
34. Heterotrimeric G proteins as fluoride targets in bone
35. The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades
36. Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
37. PI 3-kinase gamma and protein kinase C-zeta mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor
38. A potential role for extracellular signal-regulated kinases in prostaglandin F2alpha-induced protein synthesis in smooth muscle cells