Cornea-responsive medullary dorsal horn neurons: Modulation by local opoids and projections to thalamus and brain stem

Journal of Neurophysiology

Volumn 84, Issue 2, 2000, Pages 1050-1061

  Hirata, Harumitsu ^a   Takeshita, Shinichiro ^a   Hu, James W ^b   Bereiter, David A ^a  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; MORPHINE SULFATE; NALOXONE; OPIATE AGONIST; OPIATE ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA; DRUG EFFECT; EYELID REFLEX; MALE; NERVE CELL; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; TRIGEMINAL NUCLEUS;

EID: 0033841549     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.2000.84.2.1050     Document Type: Article

References (66)

1. Delta-opioid receptor immunoreactivity: Distribution in brainstem and spinal cord, and relationship to biogenic amines and enkephalin
2. Morphine and somatostatin analogue reduce c-fos expression in trigeminal subnucleus caudalis produced by corneal stimulation in the rat
3. Thalamic projections of corneal-responsive neurons from medullary dorsal horn in the rat
4. The NMDA receptor antagonist MK-801 reduces Fos-like immunoreactivity in central trigeminal neurons and blocks select endocrine and autonomic responses to corneal stimulation in the rat
5. Caudal portions of the spinal trigeminal complex are necessary for autonomic responses and display Fos-like immunoreactivity after corneal stimulation in the cat
6. Corneal pain evoked by thermal stimulation
7. Parasympathetic innervation of rat peri-orbital smooth muscle: Prejunctional cholinergic inhibition of sympathetic neurotransmission without direct postjunctional actions
8. The organization of trigeminotectal and trigeminothalamic neurons in rodents: A double-labeling study with fluorescent dyes
9. Effects of systemic morphine on lamina I spinothalamic tract neurons in the cat
10. Morphine administered in the substantia gelatinosa of the spinal trigeminal nucleus caudalis inhibits nociceptive activities in the spinal trigeminal nucleus oralis
11. Effects of systemic morphine on the activity of convergent neurons of spinal trigeminal nucleus oralis in the rat
12. Effect of trigeminal subnucleus caudalis cold block on the cerebrovascular-evoked responses of rostral trigeminal complex neurons
13. Electrophysiological studies on the effects of intrathecal morphine on nociceptive neurones in the rat dorsal horn
14. Immunohistochemical localization of μ-opioid receptors in the central nervous system of the rat
15. Presynaptic excitability changes produced in brain stem endings of tooth pulp afferents by raphe and other central and peripheral influences
16. Effects of morphine micro-injections into the trigeminal sensory complex on the formalin test in the rat
17. Spinal and trigeminal mechanisms of nociception
18. Electrophysiology of opioids
19. A role for the basal ganglia in nicotinic modulation of the blink reflex
20. Organization of trigeminothalamic tracts and other thalamic afferent systems of the brainstem in the rat: Presence of gelatinos a neurons with thalamic connections
21. Inputs to trigeminal brain stem neurons from facial, oral, tooth pulp and pharyngolarygeal tissues. II. Role of trigeminal nucleus caudalis in modulating responses to innocuous and noxious stimuli
22. Kappa-opioid receptors also increase potassium conductance
23. μ-opioid agonists inhibit spinal trigeminal substantia gelatinosa neurons in guinea pig and rat
24. Distribution of Fos-like immunoreactivity in the caudal brainstem of the rat following noxious chemical stimulation of the temporomandibular joint
25. Responses of medullary dorsal horn neurons to corneal stimulation by CO2 pulses: Intensity encoding, effects of morphine thalamic projections in the rat
26. Response properties of nociceptive and non-nociceptive neurons in the rat's trigeminal subnucleus caudalis (medullary dorsal horn) related to cutaneous and deep craniofacial afferent stimulation and modulation by diffuse noxious inhibitory controls
27. Effects of spinal kappa-opioid receptor agonists on the responsiveness of nociceptive superficial dorsal horn neurons
28. Ascending and descending internuclear connections of the trigeminal sensory nuclei in the cat. A study with the retrograde and anterograde horseradish peroxidase technique
29. Intersubnuclear connections within the rat trigeminal brainstem complex
30. Effects of iontophoresed opioids on physiologically characterized laminae I and II dorsal horn neurons in the cat spinal cord
31. Comparison of thermal sensitivity of the forehead, lip, conjunctiva and cornea
32. Actions of opioids on excitatory and inhibitory transmission in substantia gelatinosa of adult rat spinal cord
33. Axonal transport studies of the sensory trigeminal complex
34. Sensory nerves of the cornea and cutaneous sensibility
35. Antidromic activation of neurones as an analytic tool in the study of the central nervous system
36. Adrenalectomy enhances Fos-like immunoreactivity within the spinal trigeminal nucleus induced by noxious thermal stimulation of the cornea
37. Lamina-specific effects of morphine and naloxone in dorsal horn spinal cord in vitro
38. Immunohistochemical localization of the cloned kappa-1 receptor in the rat CNS and pituitary
39. The central projections of trigeminal primary afferent neurons in the cat as determined by the transganglionic transport of horseradish peroxidase
40. Corneal sensory pathway in the rat: A horseradish peroxidase tracing study
41. Differential distribution of Fos-like immunoreactivity in the spinal trigeminal nucleus after noxious and innocuous thermal and chemical stimulation of rat cornea
42. Encoding of corneal input in two distinct regions of the spinal trigeminal nucleus in the rat: Cutaneous receptive field properties, responses to thermal and chemical stimulation, modulation by diffuse noxious inhibitory controls, and projections to the parabrachial area
43. Differential effects of morphine on corneal-responsive neurons in rostral versus caudal regions of spinal trigeminal nucleus in the rat
44. The medullary dorsal horn: A target for the expression of opiate effects on the perceived intensity of noxious heat
45. Corneal and periocular representation within the trigeminal sensory complex in the cat studied with transganglionic transport of horseradish peroxidase
46. Trigeminal projections to the peribrachial region in the muskrat
47. The trigeminally evoked blink reflex. I. Neuronal circuits
48. The interstitial system of the spinal trigeminal tract in the rat: Anatomical evidence for morphological and functional heterogeneity
49. Anatomy of central nervous system pathways related to head pain
50. Analgesia for orofacial nociception produced by morphine microinjection into the spinal trigeminal complex
51. Actions of morphine and met-enkephalin-amide on nociceptor driven neurones in substantia gelatinosa and deeper dorsal horn
52. Hyperpolarizing influence of trigeminal nucleus caudalis on primary afferent preterrninals in trigeminal nucleus oralis
53. The neurobiology of facial and dental pain: Present knowledge, future directions
54. Oral and facial representation within the medullary and upper cervical dorsal horns in the cat
55. Oral and facial representation in the trigeminal principal and rostral spinal nuclei of the cat
56. Studies on pain conduction in the trigeminal nerve. A contribution to the surgical treatment of facial pain
57. Distribution of Fos-like immunoreactivity in the medullary and upper cervical dorsal horn produced by stimulation of dural blood vessels in the rat
58. Somatotopic and laminar organization of Foslike immunoreactivity in the medullary and cervical dorsal horn induced by noxious facial stimulation in the rat
59. Lacrimal preganglionic neurons form a subdivision of the superior salivatory nucleus of rat: Transneuronal labelling by pseudorabies virus
60. Opioid-mediated inhibition from the subnucleus caudaiis of spinal trigeminal nucleus to the neurons in the subnucleus oralis
61. Opioids modulate N-methyl-D-aspartic acid (NMDA)-evoked responses of trigeminothalamic neurons
62. Lamina-specific alterations of C fibre evoked activity by morphine in the dorsal horn of the rat spinal cord
63. Pharmacology and mechanisms of opioid analgesic activity
64. Opioids modulate N-methyl-D-aspartic acid (NMDA)-evoked responses of neurons in the superficial and deeper dorsal horn of the medulla (trigeminal nucleus caudalis)