The NMDA receptor antagonist MK-801 reduces Fos-like immunoreactivity in central trigeminal neurons and blocks select endocrine and autonomic responses to corneal stimulation in the rat

Pain

Volumn 64, Issue 1, 1996, Pages 179-189

  Bereiter, David A ^a,b   Bereiter, Dominique F ^b   Hathaway, Charles B ^b  

^a BROWN UNIVERSITY   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

Adrenocorticotropin; c Fos; Catecholamine; Cornea; Nociception; Trigeminal system

Indexed keywords

ALLYL ISOTHIOCYANATE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BLOOD PRESSURE; CATECHOLAMINE BLOOD LEVEL; CONTROLLED STUDY; CORNEA; CORTICOTROPIN BLOOD LEVEL; HEART RATE; IMMUNOCYTOCHEMISTRY; INTRACEREBRAL DRUG ADMINISTRATION; MALE; NOCICEPTION; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; RAT; TRIGEMINAL NERVE;

EID: 0030070939     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3959(95)00095-X     Document Type: Article

References (57)

1. Antoni, F.A., Hypothalamic control of adrenocorticotropin secretion: advances since the discovery of 41-residue corticotropin-releasing factor, Endocrine Rev., 7 (1986) 351-378.
2. Azerad, J., Boucher, Y. and Pollin, B., Occurrence of glutamate in primary sensory trigeminal neurons innervating the rat dental pulp, CR Acad. Sci. Paris, 314 (1992) 469-475.
3. Bazil, M.K. and Gordon, F.J., Spinal NMDA receptors mediate pressor responses evoked from the rostral ventrolateral medulla, Am. J. Physiol., 260 (1991) H267-H275.
4. 3H]GABA, J. Auton. Nerv. Syst., 50 (1994) 109-122.
5. Belmonte, C., Gallar, J., Pozo, M.A. and Rebollo, I., Excitation by irritant chemical substances of sensory afferent units in the cat's cornea, J. Physiol., 437 (1991) 709-725.
6. Belmonte, C. and Giraldez, F., Responses of cat corneal sensory receptors to mechanical and thermal stimulation, J. Physiol., 321 (1981) 355-368.
7. Bereiter, D.A., Microinjections of glutamate within trigeminal subnucleus interpolaris alters adrenal and autonomie function in the cat, Brain Res., 622 (1993) 155-162.
8. Bereiter, D.A., Benetti, A.P. and Thrivikraman, K.V., Thermal nociception potentiates the release of ACTH and norepinephrine by blood loss, Am. J. Physiol., 259 (1990) R1236-1242.
9. Bereiter, D.A. and Bereiter, D.F., NMDA and non-NMDA glutamate receptor subtypes contribute to the expression of c-fos in trigeminal subnucleus caudalis after chemical stimulation of the cornea in the rat, Soc. Neurosci. Abstr., 19 (1993) 110.
10. Bereiter, D.A. and Gann, D.S., Adrenal secretion of catecholamines evoked by chemical stimulation of trigeminal nucleus caudalis in the cat, Neuroscience, 25 (1988) 697-704.
11. Bereiter, D.A., Hathaway, C.B. and Benetti, A.P., Caudal portions of the spinal trigeminal complex are necessary for autonomic responses and display Fos-like immunoreactivity after corneal stimulation in the cat, Brain Res., 657 (1994) 73-82.
12. Beuerman, R.W. and Tanelian, D.L., Corneal pain evoked by thermal stimulation, Pain, 7 (1979) 1-14.
13. Boucher, Y., Pollin, B. and Azerad, J., Microinfusions of excitatory amino acid antagonists into the trigeminal sensory complex antagonize the jaw opening reflex in freely moving rats, Brain Res., 614 (1993) 155-163.
14. Clements, J.R. and Beitz, A.J., An electron microscopic description of glutamate-like immunoreactive axon terminals in the rat principal sensory and spinal trigeminal nuclei, J. Comp. Neurol., 309 (1991) 271-280.
15. Clements, J.R., Magnusson, K.R., Hautman, J. and Beitz, A.J., Rat tooth pulp projections to spinal trigeminal subnucleus caudalis are glutamate-like immunoreactive, J. Comp. Neurol., 309 (1991) 281-288.
16. Dahl, J.B. and Kehlet, H., The value of pre-emptive analgesia in the treatment of postoperative pain, Br. J. Anaesth., 70 (1993) 434-439.
17. Davies, J. and Watkins, J.C., Role of excitatory amino acid receptors in mono- and polysynaptic excitation in the cat spinal cord, Exp. Brain Res., 49 (1983) 280-290.
18. Daw, N.W., Stein, P.S.G. and Fox, K., The role of NMDA receptors in information processing, Annu. Rev. Neurosci., 16 (1993) 207-222.
19. Dickenson, A.H., NMDA receptor antagonists as analgesics. In: H. L. Fields and J. C. Liebeskind (Eds.), Progress in Pain Research and Management, IASP Press, Seattle, WA, 1994, pp. 173-187.
20. Gallar, J., Pozo, M.A., Tuckett, R.P. and Belmonte, C., Response of sensory units with unmyelinated fibres to mechanical, thermal and chemical stimulation of the cat's cornea., J. Physiol., 468 (1993) 609-622.
21. Gann, D.S. and Lilly, M.P., The endocrine response to injury, Prog. Crit. Care Med., 1 (1984) 15-47.
22. Jacquin, M.F., Chiaia, N.L., Haring, J.H. and Rhoades, R.W., Intersubnuclear connections within the rat trigeminal brainstem complex, Somatosens. Motor Res., 7 (1990) 399-420.
23. Jänig, W., Systemic and specific autonomic reactions in pain: efferent, afferent and endocrine components, Eur. J. Anaesthesiol., 2 (1985) 319-346.
24. Jänig, W. and McLachlan, E.M., Characteristics of function-specific pathways in the sympathetic nervous system, Trends Neurosci., 15 (1992) 475-481.
25. Jezova, D., Oliver, C. and Jurcovicova, J., Stimulation of adrenocorticotropin but not prolactin and catecholamine release by N-methyl-aspartic acid, Neuroendocrinology, 54 (1991) 488-492.
26. Kehl, L.J., Gogas, K.R., Lichtblau, L., Pollock, C.H., Mayes, M., Basbaum, A.I. and Wilcox, G.L., The NMDA antagonist MK801 reduces noxious stimulus-induced FOS expression in the spinal cord dorsal horn. In: M.R. Bond, J.E. Charlton and C.J. Woolf (Eds.), Proc. VIth World Congress on Pain. Elsevier, Amsterdam, 1991, pp. 307-311.
27. Kehlet, H., Surgical stress: the role of pain and analgesia, Br. J. Anaesth., 63 (1989) 189-195.
28. Kehlet, H., The surgical stress response: should it be prevented?, Can. J. Surg., 34 (1991) 565-567.
29. Kenshalo, D.R., Comparison of thermal sensitivity of the forehead, lip, conjunctiva and cornea, J. Appl. Physiol., 15 (1960) 987-991.
30. Kubo, T. and Kihara, M., N-Methyl-D-aspartate receptors mediate tonic vasodepressor control in the caudal ventrolateral medulla of the rat, Brain Res., 451 (1988) 366-370.
31. Leibowitz, H.M., Management of inflammation in the cornea and conjunctiva, Ophthalmology, 87 (1980) 753-758.
32. Lu, J., Hathaway, C.B. and Bereiter, D.A., Adrenalectomy enhances Fos-like immunoreactivity within the spinal trigeminal nucleus induced by noxious thermal stimulation of the cornea, Neuroscience, 54 (1993) 809-818.
33. Magnusson, K.R., Larson, A.A., Madl, J.E., Altschuler, R.A. and Beitz, A.J., Co-localization of fixative-modified glutamate and glutaminase in neurons of the spinal trigeminal nucleus of the rat: an immunohistochemical and immunoradiochemical analysis, J. Comp. Neurol., 247 (1986) 477-490.
34. Marfurt, C.F., The central projections of trigeminal primary afferent neurons in the cat as determined by the transganglionic transport of horseradish peroxidase, J. Comp. Neurol., 203 (1981) 785-798.
35. Marfurt, C.F. and Del Toro, D.R., Corneal sensory pathway in the rat: a horseradish peroxidase tracing study, J. Comp. Neurol., 261 (1987) 450-459.
36. Menetrey, D. and Basbaum, A.I., Spinal and trigeminal projections to the nucleus of the solitary tract: a possible substrate for somatovisceral and viscerovisceral reflex activation, J. Comp. Neurol., 255 (1987) 439-450.
37. 3H]glutamate-binding sites in rat brain, J. Neurosci., 5 (1985) 2909-2919.
38. Monassier, L., Tibirica, E., Roegel, J.-C., Mettauer, B., Feldman, J. and Bousquet, P., Prevention by NMDA receptor antagonists of the centrally-evoked increases of cardiac inotropic responses in rabbits, Br. J. Pharmacol., 111 (1994) 1347-1354.
39. Olsen, U.B. and Lund, A., Inhibition by glutamate antagonists, MK-801 and NBQX, of cutaneous-cardiovascular pain reflex in rats, Eur. J. Pharmacol., 203 (1991) 133-135.
40. Panneton, W.M. and Burton, H., Corneal and periocular representation within the trigeminal sensory complex in the cat studied with transganglionic transport of horseradish peroxidase, J. Comp. Neurol., 199 (1981) 327-344.
41. Patchev, V.K., Karalis, K. and Chrousos, G.P., Effects of excitatory amino acid transmitters on hypothalamic corticotropin-releasing hormone (CRH) and arginine-vasopressin (AVP) release in vitro: implications in pituitary-adrenal regulation, Brain Res., 633 (1994) 312-316.
42. Rozsa, A.J. and Beuerman, R.W., Density and organization of free nerve endings in the corneal epithelium of the rabbit, Pain, 14 (1982) 105-120.
43. 3H]MK-801 binding in rat brain, J. Neurochem., 60 (1993) 1344-1353.
44. Slugg, R.M. and Light, A.R., Spinal cord and trigeminal projections to the pontine parabrachial region in the rat as demonstrated With Phaseolus vulgaris leucoagglutinin, J. Comp. Neurol., 339 (1994) 49-61.
45. Somogyi, P., Minson, J.B., Morilak, D., Llewellyn-Smith, I., McIlhinney, J.R.A. and Chalmers, J., Evidence for an excitatory amino acid pathway in the brainstem and for its involvement in cardiovascular control, Brain Res., 496 (1989) 401-407.
46. Strassman, A.M. and Voss, B.P., Somatotopic and laminar organization of Fos-like immunoreactivity in the medullary and cervical dorsal horn induced by noxious facial stimulation in the rat, J. Comp. Neurol., 331 (1993) 495-516.
47. Tallaksen-Greene, S.J., Young, A.B., Penny, J.B. and Beitz, A.J., Excitatory amino acid binding sites in the trigeminal principal sensory and spinal trigeminal nuclei of the rat, Neurosci. Lett., 141 (1992) 79-83.
48. Todd, A.J., Spike, R.C., Price, R.F. and Neilson, M., Immunocytochemical evidence that neurotensin is present in glutamatergic neurons in the superficial dorsal horn of the rat, J. Neurosci., 14 (1994) 774-784.
49. Tolle, T.R., Castro-Lopes, J.M., Evan, G. and Zieglgansberger, W., Ed., C-fos induction in the spinal cord following noxious stimulation: prevention by opiates but not by NMDA antagonists. In: M.R. Bond, I.E. Charlton and C.J. Woolf (Eds.), Proc. VIth World Congress on Pain. Elsevier, Amsterdam, 1991, pp. 299-305.
50. Van den Pol, A.N., Wuarin, J.-P. and Dudek, F.E., Glutamate, the dominant excitatory transmitter in neuroendocrine regulation, Science, 250 (1990) 1276-1278.
51. Wilcox, G.L., Excitatory neurotransmitters and pain. In: M.R. Bond, J.E. Charlton and C.J. Woolf (Eds.), Proc. VIth World Congress on Pain. Elsevier, Amsterdam, 1991, pp. 97-117.
52. Winer, B.J., Statistical Principles in Experimental Design, McGraw-Hill, New York, 1971, pp. 514-603.
53. Wisden, W., Errington, M.L., Williams, S., Dunnett, S.B., Waters, C., Hitchcock, D., Evan, G., Bliss, T.V.P. and Hunt, S.P., Differential expression of immediate early genes in the hippocampus and spinal cord, Neuron, 4 (1990) 603-614.
54. Woolf, C.J. and Chong, M.-S., Preemptive analgesia-treating postoperative pain by preventing the establishment of central sensitization, Anesth. Analg., 77 (1993) 362-379.
55. Woolf, C.J. and Wall, P.D., Relative effectiveness of C primary afferent fibers of different origins in evoking a prolonged facilitation of the flexor reflex in the rat, J. Neurosci., 6 (1986) 1433-1442.
56. Yousef, K.A., Tepper, P.G., Molina, P.E., Abumrad, N.N. and Lang, C.H., Differential control of glucoregulatory hormone response and glucose metabolism by NMDA and kainate, Brain Res., 634 (1994) 131-140.
57. Zander, E. and Weddell, G., Observations on the innervation of the cornea, J. Anat., 85 (1951) 68-99.