Effects of morphine microinjections into the trigeminal sensory complex on the formalin test in the rat

Experimental Neurology

Volumn 142, Issue 2, 1996, Pages 331-339

  Duale, Christian ^a   Luccarini, Philippe ^a   Cadet, Remi ^a   Woda, Alain ^a  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FORMALDEHYDE; MORPHINE;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CONTROLLED STUDY; HISTOLOGY; INTRACEREBRAL DRUG ADMINISTRATION; MALE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD; TRIGEMINAL NUCLEUS;

EID: 0030560755     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1996.0202     Document Type: Article

References (58)

1. 1. ABBOTT, F. V., AND R. MELZACK. 1982. Brainstem lesions dissociate neural mechanisms of morphine analgesia in different kinds of pain. Brain Res. 251: 149-155.
2. 2. AIGOUY, L., J. C. FONDRAS, J. PAJOT, P. SCHOEFFLER, AND A. WODA. 1992. Intrathecal midazolam versus intrathecal morphine in orofacial nociception: an experimental study in rats. Neurosci. Lett. 139: 97-99.
3. 3. ANDERSEN, R. K., J. P. LUND, AND E. PUIL. 1978. Enkephalin and substance P effects related to trigeminal pain. Can. J. Physiol. Pharmacol. 56: 216-222.
4. 4. ARVIDSSON, J., K. PFALLER, AND S. GMEINER. 1992. The ganglionic origins and central projections of primary sensory neurons innervating the upper and lower lips in the rat. Somatosens. Motor Res. 9: 199-209.
5. 5. ATWEH, S. F., AND M. J. KUHAR. 1977. Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla. Brain Res. 124: 53-67.
6. 6. AZERAD, J., A. WODA, AND D. ALBE-FESSARD. 1982. Physiological properties of neurons in different parts of the cat trigeminal sensory complex. Brain Res. 246: 7-21.
7. 7. CADET, R., L. AIGOUY, AND A. WODA. 1995. Enhanced nociceptive behaviour following conditioning injection of formalin in the perioral area of the rat. Brain Res. 676: 189-195.
8. 8. CLAVELOU, P., J. PAJOT, R. DALLEL, AND P. RABOISSON. 1989. Application of the formalin test to the study of orofacial pain in the rat. Neurosci. Lett. 103: 349-353.
9. 9. CLAVELOU, P., R. DALLEL, T. ORLIAGUET, A. WODA, AND P. RABOISSON. 1995. The orofacial formalin test in rats: effects of various formalin concentrations. Pain 62: 295-301.
10. 10. DALLEL, R., P. RABOISSON, P. AUROY, AND A. WODA. 1988. The rostral part of the trigeminal sensory complex is involved in orofacial nociception. Brain Res. 448: 7-19.
11. 11. DALLEL, R., P. CLAVELOU, AND A. WODA. 1989. Effects of tractotomy on nociceptive reactions induced by tooth pulp stimulation in the rat. Exp. Neurol. 106: 78-84.
12. 12. DALLEL, R., P. RABOISSON, A. WODA, AND B. J. SESSLE. 1990. Properties of nociceptive and non-nociceptive neurons in trigeminal subnucleus oralis of the rat. Brain Res. 521: 95-106.
13. 13. DALLEL, R., P. RABOISSON, P. CLAVELOU, M. SAADE, AND A. WODA. 1995. Evidence for a peripheral origin of the tonic nociceptive response to subcutaneous formalin. Pain 61: 11-16.
14. 14. DICKENSON, A. H., AND D. LEBARS. 1987. Supraspinal morphine and descending inhibitions acting on the dorsal horn of the rat. J. Physiol. (London) 384: 81-107.
15. 15. EISENBERG, E., B. P. VOS, AND A. M. STRASSMAN. 1993. The NMDA antagonist Memantine blocks pain behavior in a rat-model of formalin-induced facial pain. Pain 54: 301-307.
16. 16. FRENK, H., A. LIBAN, R. BALAMUTH, AND G. URCA. 1982. Opiate and non-opiate aspects of morphine induced seizures. Brain Res. 253: 253-261.
17. 17. GOBEL, S., AND M. B. PURVIS. 1972. Anatomical studies of the organization of the spinal V nucleus: the deep bundles and the spinal V tract. Brain Res. 48: 27-44.
18. 18. GOBEL, S., S. HOCKFIELD, AND M. A. RUDA. 1981. Anatomical similarities between medullary and spinal dorsal horns. In Oral-Facial Sensory and Motor Functions (Y. Kawamura and R. Dubner, Eds.), pp. 211-223. Quintessence, Tokyo.
19. 19. GRAHAM, S. H., F. R. SHARP, AND W. DILLON. 1988. Intraoral sensation in patient with brain stem lesions: role of the rostral spinal trigeminal nuclei in pons. Neurology 38: 1529-1533.
20. 20. HALEY, J. E., A. F. SULLIVAN, AND A. H. DICKENSON. 1990. Evidence for spinal N-Methyl-D-Aspartate receptor involvement in prolonged chemical nociception in the rat. Brain Res. 518: 218-226.
21. 21. HAYASHI, H., R. SUMINO, AND B. J. SESSLE. 1984. Functional organization of trigeminal subnucleus interpolaris: nociceptive and innocuous afferent inputs, projections to thalamus, cerebellum, and spinal cord, and descending modulation from periaqueductal gray. J. Neurophysiol. 51: 890-905.
22. 22. HILL, R. G., T. E. SALT, AND C. M. PEPPER. 1982. Comparison of the effectiveness of intravenous morphine at attenuating the nociceptive responses of medullary dorsal horn and thalamic neurones. Life Sci. 31: 2331-2334.
23. 23. IKEGAMI, S., AND H. KAWAMURA. 1979. Avoidance conditioning to tooth pulp stimulation in the cat after bulbar transection. Physiol. Behav. 23: 593-596.
24. 24. JACQUIN, M. F., R. A. STENNETT, W. E. RENEHAN, AND R. W. RHOADES. 1988. Structure-function relationships in the rat brainstem subnucleus interpolaris: II. Low and high threshold trigeminal primary afferents. J. Comp. Neurol. 267: 107-130.
25. 25. JESSEL, T. M., AND L. L. IVERSEN. 1977. Opiate analgesics inhibit substance P release from rat trigeminal nucleus. Nature 268: 549-551.
26. 26. JONES, S. L., AND G. F. GEBHART. 1988. Inhibition of spinal nociceptive transmission from the midbrain, pons and medulla in the rat: activation of descending inhibition by morphine, glutamate and electrical stimulation. Brain Res. 460: 281-296.
27. 27. KHACHATURIAN, H., M. E. LEWIS, AND S. J. WATSON. 1983. Enkephalin systems in diencephalon and brainstem of the rat. J. Comp. Neurol. 220: 310-320.
28. 28. KHAYYAT, G. F., Y. J. YU, AND R. B. KING. 1975. Response patterns to noxious and non-noxious stimuli in rostral trigeminal relay nuclei. Brain Res. 97: 47-60.
29. 29. KLEIN, B. G., B. R. MISRA, AND C. F. WHITE. 1991. Orofacial pain sensitivity in adult rats following neonatal infraorbital nerve transection. Behav. Brain Res. 46: 197-201.
30. 30. LUCCARINI, P., R. CADET, M. SAADE, AND A. WODA. 1995. Antinociceptive effect of morphine microinjections into the spinal trigeminal subnucleus oralis. NeuroReport 6: 365-368.
31. 31. MARFURT, C. F., AND D. F. TURNER. 1984. The central projections of tooth pulp afferent neurons in the rat as determined by the transganglionic transport of Horseradish Peroxidase. J. Comp. Neurol. 223: 535-547.
32. 32. MATTHEWS, M. A., T. V. HERNANDEZ, AND S. L. LILES. 1987. Immunocytochemistry of enkephalin and serotonin distribution in restricted zones of the rostral trigeminal spinal subnuclei: comparisons with subnucleus caudalis. Synapse 1: 512-529.
33. 33. MOKHA, S. S. 1993. Morphine differentially modulates nociceptive input in the superficial versus the deeper dorsal horn of the medulla (trigeminal nucleus caudalis) in the rat. Brain Res. 626: 318-321.
34. 8 in the rat lower brainstem. J. Comp. Neurol. 261: 193-208.
35. 35. OLIVERAS, J. L., W. MAIXNER, R. DUBNER, M. C. BUSHNELL, G. H. DUNCAN, AND D. A. THOMAS, AND R. BATES. 1986a. Dorsal horn opiate administration attenuates the perceived intensity of noxious heat stimulation in behaving monkey. Brain Res. 371: 368-371.
36. 36. OLIVERAS, J. L., W. MAIXNER, R. DUBNER, M. C. BUSHNELL, D. R. JR. KENSHALO, G. DUNCAN, D. A. THOMAS, AND R. BATES. 1986b. The medullary dorsal horn: a target for the expression of opiate effects on the perceived intensity of noxious heat. J. Neurosci. 6: 3086-3093.
37. 37. PAXINOS, G., AND C. WATSON. 1986. The rat brain in stereotaxic coordinates, 2nd ed. Academic Press, Sidney.
38. 38. PICKOFF-MATUK, J. F., J. P. ROSENFELD, AND J. G. BROTON. 1986. Lesions of the mid-spinal trigeminal complex are effective in producing perioral thermal hypoalgesia. Brain Res. 382: 291-298.
39. 39. RABOISSON, P., R. DALLEL, AND A. WODA. 1989. Responses of neurones in the ventrobasal complex of the thalamus to orofacial noxious stimulation after large trigeminal tractotomy. Exp. Brain Res. 77: 569-576.
40. 40. RABOISSON, P., P. BOURDIOL, R. DALLEL, P. CLAVELOU, AND A. WODA. 1991. Response of trigeminal subnucleus oralis nociceptive neurons to subcutaneous formalin in the rat. Neurosci. Lett. 125: 179-182.
41. 41. RABOISSON, P., R. DALLEL, P. CLAVELOU, B. J. SESSLE, AND A. WODA. 1995. Effects of subcutaneous formalin on the activity of trigeminal brainstem nociceptive neurons in the rat. J. Neurophysiol. 73: 496-505.
42. 42. ROSENFELD, J. P., C. PICKREL, AND J. G. BROTON. 1983. Analgesia for orofacial nociception produced by morphine microinjection into the spinal trigeminal complex. Pain 15: 145-155.
43. 43. SAR, M., W. E. STUMPF, R. J. MILLER, K. J. CHANG, AND P. CUATRECASAS. 1978. Immunohistochemical localization of enkephalin in rat brain and spinal cord. J. Comp. Neurol. 182: 17-38.
44. 44. SESSLE, B. J. 1987. The neurobiology of facial and dental pain: Present knowledge, future directions. J. Dent. Res. 66: 962-981.
45. 45. SHIGENAGA, Y., T. OKAMOTO, T. NISHIMORI, I. D. NASUTION, I. C. CHEN, K. TSURU, A. YOSHIDA, K. TABUCHI, M. HOSOI, AND H. TSURU. 1986. Oral and facial representation in the trigeminal principal and rostral spinal nuclei of the cat. J. Comp. Neurol. 244: 1-18.
46. 46. STRASSMAN, A. M., AND B. P. VOS. 1993. Somatotopic and laminar organization of Fos-like immunoreactivity in the medullary and upper cervical dorsal horn induced by noxious facial stimulation in the rat. J. Comp. Neurol. 331: 495-516.
47. 47. SUAREZ-ROCA, H., L. ABDULLAH, J. ZUNIGA, S. MADISON, AND W. MAIXNER. 1992. Multiphasic effect of morphine on the release of substance P from rat trigeminal nucleus slices. Brain Res. 579: 187-194.
48. 48. TALLAKSEN-GREENE, S. J., A. B. YOUNG, J. B. PENNEY, AND A. J. BEITZ. 1992. Excitatory amino-acid binding sites in the trigeminal principal sensory and spinal trigeminal nuclei of the rat. Neurosci. Lett. 141: 79-83.
49. 49. THOMAS, D. A., AND D. L. HAMMOND. 1995. Microinjection of morphine into the rat medullary dorsal horn produces a dosedependent increase in facial scratching. Brain Res. 695: 267-270.
50. 50. THOMAS, D. A., G. M. WILLIAMS, K. IWATA, D. R. KENSHALO, AND R. DUBNER. 1993. Multiple effects of morphine on facial scratching in monkeys. Anesth. Analg. 77: 933-935.
51. 51. UHL, G. R., R. R. GOODMAN, M. J. KUHAR, S. R. CHILDERS, AND S. H. SNYDER. 1979. Immunohistochemical mapping of enkephalin containing cell bodies, fibers and nerve terminals in the brain stem of the rat. Brain Res. 166: 75-94.
52. 52. UJIHARA, H., M. SASA, Y. FUJITA, AND S. TAKAORI. 1987. Opioid-mediated inhibition from the subnucleus caudalis of spinal trigeminal nucleus to the neurons in the subnucleus oralis. Brain Res. 418: 52-57.
53. 53. VYKLICKY, L., O. KELLER, P. JASTREBOFF, L. JR VYKLICKY, AND S. M. BUTKHUZI. 1977. Spinal trigeminal tractotomy and nociceptive reactions evoked by tooth pulp stimulation in the cat. J. Physiol. (Paris) 73: 379-386.
54. 54. YAKSH, T. L., AND T. A. RUDY. 1978. Narcotic analgetics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques. Pain 4: 299-359.
55. 55. YONEHARA, N., T. SHIBUTANI, H. Y. TSAI, AND R. INOKI. 1986. Effects of opioids and opioid peptide on the release of substance P-like material induced by tooth pulp stimulation in the trigeminal nucleus caudalis of the rabbit. Eur. J. Pharmacol. 129: 209-216.
56. 56. YOUNG, R. F. 1982. Effect of trigeminal tractotomy on dental sensation in humans. J. Neurosurg. 56: 812-818.
57. 57. YOUNG, R. F., AND K. M. PERRYMAN. 1986. Neuronal responses of the rostral trigeminal brain stem nuclei of macaque monkeys after chronic trigeminal tractotomy. J. Neurosurg. 65: 508-516.
58. 58. ZIMMERMAN, M. 1983. Ethical guidelines for investigation of experimental pain in conscious animals. Pain 16: 109-110.