Decreased immunoreactivity for cell-cycle regulator p27(Kip1) in Kaposi's sarcoma correlates with higher stage and extracutaneous involvement

Journal of Pathology

Volumn 191, Issue 4, 2000, Pages 387-393

  Fernández Figueras, María Teresa ^a   Puig, Lluís ^b   Penín, Rosa María ^a   Mate, José Luís ^a   Bigatà, Xavier ^a   Ariza, Aurelio ^a  

^a HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^b HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

Author keywords

AIDS; Cell cycle; HIV; Immunohistochemistry; Kaposi's sarcoma; Ki 67; p27(Kip1)

Indexed keywords

KI 67 ANTIGEN; PROTEIN P27;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CANCER STAGING; CELL CYCLE; CLINICAL ARTICLE; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN HERPESVIRUS 8; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KAPOSI SARCOMA; MALE; PRIORITY JOURNAL; SKIN BIOPSY; VIRUS INFECTION;

CELL COUNT; DOWN-REGULATION; FEMALE; GENE EXPRESSION; GENE PRODUCTS, REX; HIV INFECTIONS; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; MALE; NEOPLASM INVASIVENESS; NEOPLASM STAGING; SARCOMA, KAPOSI;

EID: 0033837554     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-9896(2000)9999:9999<::AID-PATH639>3.0.CO;2-F     Document Type: Article

References (37)

1. The enigmas of Kaposi's sarcoma
2. Kaposi's sarcoma: Advances and perspectives
3. Evidence for multiclonality in multicentric Kaposi's sarcoma
4. Monoclonal origin of multicentric Kaposi's sarcoma lesions
5. The immunoexpression of bcl-2 and p53 in Kaposi's sarcoma
6. Differential expression of p53 and Ki67 proteins in classic and iatrogenic Kaposi's sarcoma
7. Cyclin D1 and retinoblastoma protein expression in Kaposi's sarcoma
8. Immunohistochemical detection of Bcl-2 in AIDS-associated and classical Kaposi's sarcoma
9. Cip/Kip cyclin-dependent kinase inhibitors: Brakes of the cell cycle engine during development
10. Cancer prognostics: Past, present and p27
11. Mutation of cell cycle regulators. Biological and clinical implications
12. p27kip1: A multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers
13. Role of p27(Kipl) and cyclin-dependent kinase 2 in the proliferation of non-small cell lung cancer
14. Impact of the cyclin dependent kinase inhibitor p27(Kip1) on adhesion-dependent resistance of tumour cells to anticancer agents
15. Cyclin-dependent kinase inhibitor p27(Kip1) expression and interaction with other cell cycle-associated proteins in mammary carcinoma
16. Distinct altered patterns of p27(Kip1) gene expression in benign prostatic hyperplasia and prostatic carcinoma
17. Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases
18. Prognostic significance of p27(Kip1) expression in colorectal cancer: A clinicopathological characterization
19. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
20. p27 expression and gastric carcinoma
21. Aberrant p27(Kip1) expression in endocrine and other tumors
22. Expression of the cell cycle inhibitor P27(Kipl) is a new prognostic marker associated with survival in epithelial ovarian tumors
23. Reduced levels of the cell-cycle inhibitor p27(Kipl) in epithelial dysplasia and carcinoma of the oral cavity
24. Kaposi's sarcoma. A clinicopathologic review and differential diagnosis
25. Role of ubiquitinproteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
26. DNA mehtylation regulates p27(Kip1) expression in rodent pituitary lines
27. Translational control of p27(Kip1) accumulation during the cell cycle
28. Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia and pituitary tumors
29. Inhibiting CDK inhibitors: New lessons from DNA tumor viruses
30. Coupling herpesvirus to angiogenesis
31. The fight of viruses against apoptosis
32. A Bcl-2 homolog encoded by Kaposi's sarcoma-associated virus, human herpes virus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak
33. G-protein coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator
34. Cyclin encoded by KS herpesvirus
35. Degradation of p27Kip cdk inhibitor triggered by Kaposi's sarcoma virus cyclin-cdk6 complex
36. Modulation of p27(Kip1) levels by the cyclin encoded by Kaposi's sarcoma-associated herpesvirus
37. Tumorigenesis and metastasis of neoplastic Kaposi's sarcoma cell line in immunodeficient mice blocked by a human pregnancy hormone