Cytochemical and ultrastructural examination of apoptotic odontoclasts induced by bisphosphonate administration

Cell and Tissue Research

Volumn 301, Issue 3, 2000, Pages 375-387

  Watanabe, Jun Ichi ^a   Amizuka, Norio ^a   Noda, Tadashi ^a   Ozawa, Hidehiro ^a  

^a NIIGATA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Bisphosphonate; Deciduous teeth; Odontoclast; Rabbit; Ultrastructure

Indexed keywords

ACID PHOSPHATASE; BISPHOSPHONIC ACID DERIVATIVE; CATHEPSIN K; INCADRONIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; CYTOCHEMISTRY; DECIDUOUS TOOTH; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; TOOTH DEVELOPMENT;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0033837292     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410000242     Document Type: Article

References (60)

1. Substrate specificity of recombinant osteoclast-specific cathepsin K from rabbits
2. Bisphosphonates used for the treatment of bone disorders inhibit squalene synthase and cholesterol biosynthesis
3. Preliminary observation of a form of coherence therapy for osteoporosis
4. Immunoelectron microscope localization of snRNA, hnRNA, and ribosomal proteins in mouse spermatogenesis
5. Nuclear ribonucleo-protein-containing structures undergo severe rearrangement during spontaneous thymocyte apoptosis. A morphological study by electron microscopy
6. Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis
7. Effects of bisphosphonates on proliferation and viability of mouse bone marrow-derived macrophages
8. Correlation of DNA fragmentation and chromatin condensation in apoptotic nuclei of the Ser 6 mouse retina
9. The therapeutic use of bisphosphonates
10. Alkaline phosphatase activity with the nuclear pore in normal and neoplastic salivary gland tissue
11. Electron microscopic and histochemical studies of the mononuclear odontoclast of the human
12. 2MBP-coated bone
13. Diphosphonate: History and mechanism of action
14. Bisphosphonates - Pharmacology and use in the treatment of tumor induced hypercalcemia and metastatic bone disease
15. The ultrastructure of nuclear envelope of amphibian oocytes: A reinvestigation.I. The mature oocyte
16. Ultrastructure and acid phosphatase cytochemis-try of odontoclasts: Effects of parathyroid extract
17. Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gammadichloromethylene) triphosphate, by mammalian cells in vitro
18. The resorption processes of human deciduous teeth studied by light microscopy, microradiography and electron microscorpy
19. Identification of programmed cell death in situ via specific binding of nuclear DNA fragmentation
20. Immunohistochemical localization of cathepsin B, D, and L in the rat osteoclast
21. Localizasion of cathepsin B, D, and L in the rat osteoclasts by immuno-light and -electron microscopy
22. Ultrastructure of multinucleated giant cell apoptosis in foreign-body glanuloma
23. Bisphosphonates promote apoptosis m murine osteoclasts in vitro and in vivo
24. Inhibitory effect of topical administration of bisphosphonate (risedronate) on root resorption incident to orthodontic tooth movement in rats
25. Analysis of apoptosis morphology in Epstein-Barr virus positive and negative Burkittt's lymphoma cell
26. Ultrastructural and cytochemical observation of apoptotic osteoclasts induced by bisphosphonate
27. The binding of pyrophosphate and diphosphonate and two diphosphonate by hydroxyapatite crystals
28. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
29. Electron microscope studies on the origin of annulate lamellae in oocytes of Necturus
30. The structure and function of annulate lamellae: Porous cytoplasmic and intranuclear membranes
31. Localization of cathepsin K in human osteoclasts by In situ hybridization and immunohistochemistry
32. Nuclear reorganisation in ram spermatids
33. Migration and phenotype transformation of osteoclast precursors into mature osteoclasts: The effect of a bisphosphonate
34. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras
35. Ultrastructural and cytochemical study of odonto-clasts in physiologic root resorption of human deciduous teeth
36. Morphological and functional properties of odontoclasts on dentine resorption
37. Bone acid phosphatase: Tartrate-resistant acid phosphatase as a marker of osteoclast function
38. Bisphosphonates act on osteoblastic cells and inhibit osteoclast formation in mouse marrow cultures
39. Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease
40. Detection of collagenase mRNA in odontoclasts of bovine root-resorbing tissue by in situ hybridization
41. Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum
42. Odontoclastic resorption at the pulpal surface of coronal dentin prior to the shedding of human deciduous teeth
43. Odontoclastic resorption of the superficial nonmineralized layer of predentine in the shedding of human deciduous teeth
44. Cytodifferentiation of the odontoclast prior to the shedding of human deciduous teeth: An ultrastructural and cytochemical study
45. Bisphosphonates act on rat bone resorption through the mediation of osteoblasts
46. Immunocytochemical localization of collagenase in isolated mouse bone cells
47. Biochemical and immunohistochemistry studies on collagenase in resorbing bone in tissue culture
48. Isolation and characterization of collagenase synthesized by mouse bone cells in culture
49. Degratiative processes of connective tissue proteins with special emphasis on collagenolysis and bone resorption
50. Immunocytochemical localization of cathepsin B and G in odontoclasts of human deciduous teeth
51. Dentin resorption mediated by odontoclasts in physiological root resorption of human deciduous teeth
52. Cytodifferentiation and degeneration of odontoclasts in physiologic root resorption of kitten deciduous teeth
53. Cellular roles in physiological root resorption of deciduous teeth in the cat
54. Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure
55. Negative staining and adenosine triphos-phatase activity of annulate lamella of newt oocytes
56. Protein-tyrosine phosphatase activity regulates osteoclast formation and function: Inhibition by alendronate
57. Structure-activity relationships of various bisphosphonates
58. Effect of YM175 on hypercalcemia induced by human squamous cell carcinoma of oral cavity
59. Endocy-tosis in odontoclasts and osteoclasts using microperoxidase as a tracer
60. Observation of odontoclasts in the human deciduous teeth by tartrate-resistant acid phosphatase activity