Substrate specificity of recombinant osteoclast-specific cathepsin K from rabbits

Biological and Pharmaceutical Bulletin

Volumn 19, Issue 8, 1996, Pages 1026-1031

  Aibe, Kazuhiko ^a   Yazawa, Hidenori ^a   Abe, Kenji ^a   Teramura, Kyoko ^a   Kumegawa, Masayoshi ^b   Kawashima, Hiroyuki ^a   Honda, Kazuo ^a  

^a ASTELLAS PHARMA INC   (Japan)

^b MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

Author keywords

Escherichia coli; expression; osteoclast; proteinase; substrate specificity

Indexed keywords

CATHEPSIN;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ESCHERICHIA COLI; NONHUMAN; OSTEOLYSIS; RABBIT;

EID: 0029786152     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.19.1026     Document Type: Article

References (24)

1. Abbreviations: E-64, L-3-carboxy-2,3-trans-epoxypropionyl-leucyl-amido(4-guanidino)butane; Boc, tert-butyloxycarbonyl; Bz, benzoyl; Z, benzyloxycarbonyl; Suc, succinyl; MCA, 7-(4-methyl)coumarylamide; PCR, polymerase chain reaction; DFP, diisopropyl-fluorophosphate; PMSF, phenylmethylsulfonyl fluoride; PLCPI, pig leucocyte cysteine proteinase inhibitor; DTT, dithiothreitol; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
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