The effects of dioxin on reproduction and development

Industrial Health

Volumn 38, Issue 3, 2000, Pages 259-268

  Yonemoto, J ^a  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

Author keywords

Breast milk; Developmental effects; Dioxin; Reproductive effects; Risk assessment; TCDD

Indexed keywords

BREAST MILK; DOSIMETRY; HUMAN; LACTATION; LONGEVITY; NONHUMAN; PREGNANCY; REPRODUCTIVE TOXICITY; REVIEW; RISK ASSESSMENT; TERATOGENESIS; THYROID FUNCTION;

ANIMALIA; MAMMALIA;

EID: 0033836863     PISSN: 00198366     EISSN: None     Source Type: Journal    
DOI: 10.2486/indhealth.38.259     Document Type: Review

References (79)

1. WHO revises the Tolerable Daily Intake (TDI) for dioxins
2. Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDD), dibenzofurans (PCDFs) and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs)
3. Evidence for the role of the Ah receptor in response to dioxin
4. How important is the protein phosphorylation pathway in the toxic expression of the dioxin-type chemicals?
5. Developmental effects of dioxins
6. Toxicology of dioxins and related compounds
7. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds as antiestrogens: Characterization and mechanism of action
8. In utero exposure to low dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin alters reproductive development of female Long Evance hooded rat offspring
9. Subchronic effects of 2,3,7,8-TCDD or PCBs on thyroid hormone metabolism: Use in risk assessment
10. Short- and long-term biochemical effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Long-Evans rats
11. Dioxin reduces transforming growth factor-alpha in human keratinocytes
12. TCDD induced altered expression of growth factors may have a role in producing cleft palate and enhancing the incidence of clefts after coadministration of retinoic acid and TCDD
13. The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the hepatic estrogen and glucocorticoid receptors in congenic strains of Ah responsive and Ah nonresponsive C57BL/6J mice
14. Decreased ligand binding to the hepatic glucocorticoid and EGF receptors after 2,3,4,7,8-pentachlorodibenzofuran and 1,2,4,7,8-hexachlorodibenzofuran treatment of pregnant mice
15. Interactive regulation of Ah and glucocorticoid receptors in the synergistic induction of cleft palate by TCDD and hydrocortisone
16. Ovarian hormones enhance 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated increases in cell proliferation and preneoplastic foci in a two-stage model for rat hepatocarcinogenesis
17. TCDD-induced hyperplasia of the ureteral epithelium produces hydronephrosis in murine fetuses
18. Effects of TCDD on embryonic ureteric epithelial EGF receptor expression and cell proliferation
19. Dioxins and the Ah receptor: Probes to uncover processes in neuroendocrine development
20. Characterization of the peak period of sensivity for the induction of hydronephrosis in C57BL/6N mice following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
21. Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the golden Syrian hamster
22. Comparative developmental toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
23. Hydronephrosis in mice exposed to TCDD-contaminated breast milk: Identification of the peak period of sensitivity and assessment of potential recovery
24. TCDD alters medial epithelial cell differentiation during palatogenesis
25. Comparison of the effects of TCDD and hydrocortisone on growth factor expression provide insight into the synergistic interaction occurring in embryonic palates
26. Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor
27. Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon (AhR)-null mice
28. In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin: 1. Effects on androgenic status
29. In utero and lactational exposured of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin: 2. Effects of spermatogenesis and reproductive capability
30. In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin: 3. Effects on spermatogenesis and reproductive capability
31. Perinatal TCDD exposure alters sex differentiation in both female and male LE hooded rats
32. Exposure to TCDD during development permanently alters reproductive function in male LE rats and hamsters: Reduced ejaculated and epididymal sperm numbers and sex accessory gland weights in offspring with normal androgen status
33. A Dose-Respose analysis of the reproductive effects of a single gestational dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male Long Evans hooded rat offspring
34. In utero and lactational exposure of the male Holtzman rat to 2,3,7,8-tetrachlorodibenzo-p-dioxin: Decreased epididymal and ejaculated sperm numbers without alterations in sperm transit rate
35. Effects of developmental exposure to indole-3-carbinol or 2,3,7,8-tetrachlorodibenzo-p-dioxin on reproductive potential of male rat offspring
36. Effects of in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on responsiveness of the male rat reproductive system to testosterone stimulation in adulthood
37. In utero and lactational exposure of the male rat to 2,3,7,8-tetrachlorodibenzo-p-dioxin: Impaired prostate growth and development without inhibited androgen production
38. In utero and lactational exposure of the male rat to 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs prostate development
39. In utero and lactational exposure of the male rat to 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs prostate development. 1. Effects on gene expression
40. Partial demasculinization and feminization of sex behavior in male rats by in utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin is not associated with alterations in estrogen receptor binding or volumes of sexually differentiated brain nuclei
41. In utero and lactational exposure of female Holtzman rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin: Modulation of the estrogen signal
42. Alterations to the pituitary-gonadal axis in the peripubertal female rat exposed in utero and through lactation to 2,3,7,8-tetrachlorodibenzo-p-dioxin
43. Reproductive toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male rats: Different effects of in utero versus lactational exposure
44. Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: Effects of development of the male and female reproductive system of the mouse
45. Hormonal interactions in the effects of halogenated aromatic hydrocarbons on the developing brain
46. Vulnerability of the developing brain to thyroid abnormalities: Environmental insults to the thyroid system
47. Effects of gestational and lactational exposure to coplanar polychlorinated biphenyl (PCB) congeners or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on thyroid hormone concentrations in weanling rats
48. Lymphocyte stem cell alterations following perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
49. Towards an integrated view of thymopoiesis
50. Perinatal thymocyte antigen expression and postnatal immune development altered by gestational exposure to tetrachlorodibenzo-p-dioxin (TCDD)
51. Alterations in the developing immune system of the F344 rat after perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: I [correction of II]. Effects on the fetus and the neonate
52. Alterations in the developing immune system of the F344 rat after perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: II. Effects on the pup and the adult
53. Persistent suppression of delayed-type hypersensitivity in adult F344 rats after perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
54. P27 (Kip 1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells
55. Temperature regulation and metabolism in rats exposed perinatally to dioxin: Permanent change in regulated body temperature?
56. Autonomic and behavioral thermoregulation in golden hamsters exposed perinatally to dioxin
57. Thermoregulation in rats exposed perinatally to dioxin: Core temperature stability to altered ambient temperature, behavioral thermo-regulation, and febrile response to lipopolysaccharide
58. Paternal serum dioxin and reproductive outcomes among veterans of Operation Ranch Hand
59. Reproductive effects of herbicide exposure in Vietnam: Recent studies by the Vietnamese and others
60. Review of recent Vietnamese studies on the carcinogenic and teratogenic effects of phenoxy herbicide exposure
61. Change in sex rato with exposure to dioxin [letter]
62. Perinatal exposure to chlorinated dioxins and related chemicals on thyroid hormone status in Japanese breast-fed infants
63. Effects of perinatal exposure to PCBs and dioxins on early human development
64. Effects of perinatal PCB and dioxin exposure and early feeding mode on child development
65. Effects of environmental exposure to polychlorinated biphenyls and dioxins on growth and development in young children
66. Plasma polychlorinated biphenyl levels in Dutch preschool children either breast-fed or formula-fed during infancy
67. Effects of environmental exposure to polychlorinated biphenyls and dioxins on birth size and growth in Dutch children
68. Perinatal exposure to polychlorinated biphenyls and dioxins and its effect on neonatal neurological development
69. Neurological condition in 18-month-old children perinatally exposed to polychlorinated biphenyls and dioxins
70. Neurological condition in 42-month-old children in relation to pre-postnatal exposure to polychlorinated biphenyls and dioxins
71. Effects of dioxins and polychlorinated biphenyls on thyroid hormone status of pregnant women and their infants
72. Effects of environmental exposure to polychlorinated biphenyls and dioxins on cognitive abilities in Dutch children at 42 months of age
73. Immunologic effects of background prenatal and postnatal exposure to dioxins and polychlorinated biphenyls in Dutch infants
74. 2,3,7,8-tetrachlorodibenzo-p-dioxin in pregnant Long Evans rats: Disposition to maternal and embryo/fetal tissues
75. Acute administration of 2,3,7,8-tetraclorodibenzo-p-dioxin (TCDD) in Long Evans rats: Comparison of fetal tissue levels and adverse developmental effects
76. Developmental and reproductive effects of low-dose, steady-state maternal 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) administration
77. Alternative models for low-dose analysis of biochemical and immunological endpoints for tetrachlorodibenzo-p-dioxin
78. Characterizing dose-response I: Critical assessment of the benchmark dose concept