Transforming growth factor β induces anchorage-independent growth of NRK fibroblasts via a connective tissue growth factor-dependent signaling pathway

Cell Growth and Differentiation

Volumn 8, Issue 1, 1997, Pages 61-68

  Kothapalli, Devashish ^a   Frazier, Kendall S ^a   Welply, Annemarie ^b   Segarini, Patricia R ^b   Grotendorst, Gary R ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b FIBROGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL STIMULATION; CELL TRANSFORMATION; CHICKEN; CONNECTIVE TISSUE; CONTROLLED STUDY; FIBROBLAST; GENE EXPRESSION; MINK; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

ANIMALS; CELL ADHESION; CELL DIVISION; CELL LINE; DNA, ANTISENSE; FIBROBLASTS; GROWTH SUBSTANCES; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOGENS; RATS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 0031014983     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Celeste, A. J., Ianazzi, J. A., Taylor, R. C., Hewick, R. M., Rosen, V., Wang, E. A., and Wozney, J. M. Identification of transforming growth factor β family members present in bone-inductive protein purified from bovine bone. Proc. Natl. Acad. Sci. USA, 87: 9843-9847, 1990.
2. Wozney, J. M., Rosen, V., Byrne, M., Celeste, A. J., Moutsatsos, I., and Wang, E. A. Growth factors influencing bone development. J. Cell. Sci. Suppl., 13: 149-156, 1990.
3. Wozney, J. M. The bone morphogenetic protein family and osteogenesis. Mol. Reprod. Dev., 32: 160-167, 1992.
4. Centrella, M., Horowitz, M. C., Wozney, J. M., and McCarthy, T. L. Transforming growth factor β gene family members and bone. Endocr. Rev., 15: 27-38, 1994.
5. Ignotz, R. A., and Massagué, J. Transforming growth factor-β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J. Biol. Chem., 261: 4337-4345, 1986.
6. Roberts, A. B., Sporn, M. B., Assoian, R. K., Smith, J. M., Roche, N. S., Wakefield, L. M., Heine, U. I., Liotta, L. A., Falanga, V., Kehrl, J. H., and Fauci, A. S. Transforming growth factor type β: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc. Natl. Acad. Sci. USA, 83: 4167-4171, 1986.
7. Raghow, R., Postlethwaite, A. E., Keski-Oja, J., Moses, H. L., and Kang, A. H. Transforming growth factor β increases steady state levels of type 1 procollagen and fibronectin mRNAs post translationally in cultured fibroblasts. J. Clin. Invest., 79: 1285-1288, 1987.
8. Penttinen, R. P., Kobayashi, S., and Bornstein, P. Transforming growth factor β increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability. Proc. Natl. Acad. Sci. USA, 85: 1105-1108, 1988.
9. Massagué, J. The transforming growth factor-β family. Annu. Rev. Cell Biol., 6: 597-641, 1990.
10. Assoian, R. K., Grotendorst, G. R., Miller, D. V., and Sporn, M. B. Cellular transformation by coordinated action of three peptide growth factors from human platelets. Nature (Lond.), 309: 804-806, 1984.
11. DeLarco, J. E., and Todaro, G. J. Growth factors from murine sarcoma virus-transformed cells. Proc. Natl. Acad. Sci., USA, 75: 4001-4005, 1978.
12. Roberts, A. B., Lamb, L. C., Newton, D. L., Sporn, M. B., DeLarco, J. E., and Todaro, G. J. Transforming growth factors: isolation of polypeptides from virally and chemically transformed cells by acid/ethanol extraction. Proc. Natl. Acad. Sci. USA, 77: 3494-3498, 1980.
13. Guadagno, T. M., and Assoian, R. K. G1/S control of anchorage-independent growth in the fibroblast cell cycle. J. Cell Biol., 115: 1419-1425, 1991.
14. Assoian, R. K., Guadagno, T. M., and Dalton, S. L. Attachment control of fibroblast proliferation. In: M. S. Oka and R. G. Rupp (eds.), Cell Biology and Biotechnology, pp. 11-25. New York: Springer-Verlag, 1993.
15. Guadagno, T. M., Ohtsubo, M., Roberts, J. M., and Assoian, R. K. A link between cyclin A expression and adhesion-dependent cell cycle progression. Science (Washington DC), 262: 1572-1575, 1993.
16. Bradham, D. M., Igarashi, A., Potter, R. L., and Grotendorst, G. R. Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J. Cell Biol., 114: 1285-1294, 1991.
17. Bork, P. The modular architecture of a new family of growth regulators related to connective tissue growth factor. FEBS Lett., 327: 125-130, 1993.
18. Igarashi, A., Okochi, H., Bradham, D. M., and Grotendorst, G. R. Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. Mol. Biol. Cell, 4: 637-645, 1993.
19. Grotendorst, G. R., Okochi, H., and Hayashi, N. A novel transforming growth factor β-response element controls the expression of the connective tissue growth factor gene. Cell Growth & Differ., 7: 469-480, 1996.
20. Frazier, K., Williams, S., Kothapalli, D., Klapper, H., and Grotendorst, G. R. Stimulation of fibroblast cell growth, matrix production and granulation tissue formation by connective tissue growth factor. J. Invest. Dermatol., 107: 404-411, 1996.
21. Roberts, A. B., Anzano, M. A., Lamb, L. C., Smith, J. M., Frolik, C. A., Marquardt, H., Todaro, G. J., and Sporn, M. B. Isolation from murine sarcoma cells of novel transforming growth factors potentiated by EGF. Nature (Lond.), 295: 417-419, 1982.
22. Anzano, M. A., Roberts, A. B., Meyers, C. A., Komoriya, A., Lamb, L. C., Smith, J. M., and Sporn, M. B. Synergistic interaction of two classes of transforming growth factors from murine sarcoma cells. Cancer Res., 42: 4776-4778, 1982.
23. Frolik, C. A., Dart, L. L., Meyers, C. A., Smith, D. M., and Sporn, M. B. Purification and initial characterization of a type β transforming growth factor from human placenta. Proc. Natl. Acad. Sci. USA, 80: 3676-3680, 1983.
24. iα1 J. Biol. Chem., 268: 19851-19857, 1993.
25. Leof, E. B., Proper, J. A., Gouston, A. S., Shipley, G. D., DiCorleto, P. E., and Moses, H. L. Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor β: a proposed model for indirect mitogenesis involving autocrine activity. Proc. Natl. Acad. Sci. USA, 83: 2453-2457, 1986.
26. Battegay, E. J., Raines, E. W., Seifert, R. A., Bowen-Pope, D. F., and Ross, R. TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine platelet-derived growth factor loop. Cell, 63: 515-524, 1990.
27. Ishikawa, O., Leroy, E. C., and Trojanowska, M. Mitogenic effect of TGF-β1 on human fibroblasts involves induction of platelet-derived growth factor a receptors. J. Cell. Physiol., 145: 181-186, 1990.
28. O'Brien, T. P., Yang, G. P., Sanders, L., and Lau, L. F. Expression of cyr61, a growth factor-inducible immediate-early gene. Mol. Cell. Biol., 10: 3569-3577, 1990.
29. Kireeva, M. L., Mo, F., Yang, G. P., and Lau, L. F. Cyr61, a product of a growth factor-inducible immediate early gene, promotes cell proliferation, migration and adhesion. Mol. Cell. Biol., 16: 1326-1334, 1996.
30. Assoian, R. K., Boardman, L. A., and Drosinos, S. A preparative Suspension culture system permitting quantitation of anchorage-independent growth by direct radiolabeling of cellular DNA. Anal. Biochem., 177: 95-99, 1989.
31. Ogawa, Y., and Seyedin, S. M. Purification of transforming growth factor β1 and β2 from bovine bone and cell culture assays. Methods Enzymol., 198: 317-327, 1991.
32. Soma, Y., and Grotendorst, G. R. TGF-β stimulates primary human skin fibroblast DNA synthesis via an autocrine production of PDGF-related peptides. J. Cell. Physiol., 140: 246-253, 1989.
33. 4. Nature (Lond.), 227: 680-685, 1970.
34. Okamura, H., Sigal, C. T., Alland, L., and Resh, M. D. Rapid high-resolution Western blotting. Methods Enzymol., 254: 535-550, 1995.
35. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual, Ed. 2, pp. 1.42-1.45. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
36. Feigner, P. L., Gadek, T. R., Holm, M., Roman, R., Chan, H. W., Wenz, M., Northrop, J. P., Ringold, G. M., and Danielsen, M. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl. Acad. Sci. USA, 84: 7413-7417, 1987.
37. Strauss, W. M. Preparation of genomic DNA from mammalian tissue. In: F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (eds.), Current Protocols in Molecular Biology, Vol. 2, Suppl. 13, pp. 2.2.1-2.2.3. New York: John Wiley & Sons, 1995.