Exploiting nonneural cells to rebuild the nervous system: From bone marrow to brain

Neuroscientist

Volumn 6, Issue 5, 2000, Pages 353-361

  Azizi, S A ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Bone marrow stromal cells; Gene therapy; Mesenchymal stem cells; Neural transplantation; Stem cells

Indexed keywords

GENE PRODUCT; LEVODOPA;

ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL TRANSPLANTATION; CENTRAL NERVOUS SYSTEM; DEGENERATIVE DISEASE; GENE THERAPY; HUMAN; HUMAN CELL; MESENCHYME CELL; NEUROLOGIC DISEASE; NONHUMAN; PARKINSON DISEASE; RAT; STROMA CELL;

EID: 0033810744     PISSN: 10738584     EISSN: None     Source Type: Journal    
DOI: 10.1177/107385840000600509     Document Type: Article

References (57)

1. Neural transplantation - An experimental tool with clinical possibilities
2. Better cells for brain repair
3. Neural stem-like cells: Developmental lessons with therapeutic potential
4. Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease
5. Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats - Similarities to astrocyte grafts
6. Xenotransplantation of porcine fetal ventral mesencephalon in a rat model of Parkinson's disease: Functional recovery and graft morphology
7. Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient
8. Embryonic stem cell-derived glial precursors: A source of myelinated transplants
9. Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord
10. Scientific and ethical concerns in neural fetal tissue transplants
11. Why do neural transplants survive? An examination of some metabolic pathophysiological considerations in neural transplantation
12. Improved graft survival and striatal innervation by microtransplantation of fetal nigral cell suspensions in the rat Parkinson's model
13. The use of non-neural cells for gene delivery
14. Double transduction with GTP cyclohydrolase In and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts
15. In vivo release of dopa and dopamine from genetically engineered cells grafted to the denervated rat striatum
16. Survival of genetically engineered, adult derived rat astrocytes grafted into the 6-hydroxydopamine lesioned adult rat striatum
17. Morphological and neurochemical features of cultured primary skin fibroblasts of Fischer 344 rats following striatal implantation
18. Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease
19. Brain-derived neurotrophic factor-transduced fibroblasts: Production of BDNF and effects of grafting to the adult rat brain
20. Dopaminergic neurons protected from degeneration by GDNF gene therapy
21. Marrow stromal cells as stem cells for nonhematopoietic tissues
22. Ueber entzundung und eiterung
23. Fibroblast precursors in normal and irradiated mouse hematopoietic organs
24. Multilineage potential of adult human mesenchymal stem cells
25. Cardiomyocytes can be generated from marrow stromal cells in vitro
26. Can old cells learn new tricks?
27. Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice
28. Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta
29. Muscle regeneration by bone marrow-derived myogenic progenitors
30. Dystrophin expression in the mdx mouse restored by stem cell transplantation
31. Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice
32. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
33. Adult bone marrow stromal cells differentiate into neural cells in vitro
34. An in vitro pathway from embryonic stem cells to neurons and glia
35. Retinoic acid enhances neuronal proliferation and astroglial differentiation in cultures of CNS stem cell-derived precursors
36. Isolation and cloning of multipotential stem cells from the embryonic human CNS and establishment of transplantable human neural stem cell lines by epigenetic stimulation
37. Mice cloned from embryonic stem cells
38. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
39. Hematopoietic potential of stem cells isolated from murine skeletal muscle
40. Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo
41. Bone marrow as a potential source of hepatic oval cells
42. Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex
43. 'Global' cell replacement is feasible via neural stem cell transplantation: Evidence from the dysmyelinated shiverer mouse brain
44. Multipotential marrow stromal cells transduced to produce L-DOPA: Engraftment in a rat model of Parkinson's disease
45. Generation of DOPA-producing astrocytes by retroviral transduction of the human tyrosine hydroxylase gene: In vitro characterization and in vivo effects in the rat Parkinson's model
46. Survival, integration, and differentiation of neural stem cell lines after transplantation to the adult rat striatum
47. Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes
48. Foreign gene expression in an organotypic culture of cortical anlage after in vivo electroporation
49. Limits of neurogenesis in primates
50. Neurogenesis in the adult human hippocampas
51. Neurogenesis in the neocortex of adult primates
52. Neural substrates for the effects of rehabilitative training on motor recovery after ischemic infarct
53. Adult brain retains the potential to generate oligodendroglial progenitors with extensive myelination capacity
54. Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination
55. Immortalized postnatally-derived cerebellar progenitors can engraft and participate in development of multiple structures at multiple stages along mouse neuroaxis
56. Engraftment of immortalized multipotent progenitor lines into the subependymal germinal zone of adult mice
57. Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow