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Volumn 30, Issue 10, 2000, Pages 2908-2917
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Sequence analysis of light chain genes from human intestinal plasma cells demonstrates that lambda genes are almost all in-frame and highly mutated and most kappa genes are highly mutated when in-frame and minimally mutated when out-of-frame
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Author keywords
Human; Immunoglobulin gene; Mucosa; Plasma cell
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Indexed keywords
IMMUNOGLOBULIN A;
IMMUNOGLOBULIN LIGHT CHAIN;
IMMUNOGLOBULIN M;
ARTICLE;
B LYMPHOCYTE;
CONFORMATION;
CONTROLLED STUDY;
GENE EXPRESSION;
GENE MUTATION;
GENE REARRANGEMENT;
GERM LINE;
HUMAN;
HUMAN CELL;
IMMUNOGLOBULIN GENE;
INTESTINE CELL;
MUCOSA;
NUCLEOTIDE SEQUENCE;
PLASMA CELL;
PRIORITY JOURNAL;
SEQUENCE ANALYSIS;
SEQUENCE HOMOLOGY;
AGED;
AGED, 80 AND OVER;
AMINO ACID MOTIFS;
AMINO ACID SUBSTITUTION;
BASE SEQUENCE;
COLON;
DNA MUTATIONAL ANALYSIS;
FEMALE;
GENE REARRANGEMENT, B-LYMPHOCYTE, LIGHT CHAIN;
GENES, IMMUNOGLOBULIN;
HUMAN;
ILEUM;
IMMUNOGLOBULINS, KAPPA-CHAIN;
IMMUNOGLOBULINS, LAMBDA-CHAIN;
INTESTINAL MUCOSA;
MALE;
MOLECULAR SEQUENCE DATA;
MUTATION;
PLASMA CELLS;
POINT MUTATION;
SEQUENCE ALIGNMENT;
SEQUENCE HOMOLOGY, NUCLEIC ACID;
SUPPORT, NON-U.S. GOV'T;
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EID: 0033793199
PISSN: 00142980
EISSN: None
Source Type: Journal
DOI: 10.1002/1521-4141(200010)30:10<2908::AID-IMMU2908>3.0.CO;2-E Document Type: Article |
Times cited : (6)
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References (38)
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