CXC chemokines IP-10 and Mig expression and direct migration of pulmonary CD8+/CXCR3+ T cells in the lungs of patients with HIV infection and T-cell alveolitis

American Journal of Respiratory and Critical Care Medicine

Volumn 162, Issue 4 I, 2000, Pages 1466-1473

  Agostini, Carlo ^a   Facco, Monica ^a   Siviero, Marta ^a   Carollo, Davide ^a   Galvan, Silvia ^a   Cattelan, Anna Maria ^a   Zambello, Renato ^a   Trentin, Livio ^a   Semenzato, Gianpietro ^a,b  

^a UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHEMOKINE; CHEMOKINE RECEPTOR; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 15;

ADULT; ARTICLE; CHEMOTAXIS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIGAND BINDING; LUNG ALVEOLITIS; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; LYMPHOCYTE MIGRATION; LYMPHOCYTIC INFILTRATION; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

EID: 0033769729     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.162.4.2003130     Document Type: Article

References (31)

1. Role of bronchoalveolar lavage in predicting survival of patients with human immunodeficiency virus infection
2. HIV and pulmonary immune responses
3. Lymphocytic alveolitis, bronchoalveolar lavage viral load, and outcome in Human Immuno-deficiency Virus infection
4. Expression of TNF receptors by T cells and membrane TNF-alpha by alveolar macrophages suggests a role for TNF-alpha in the regulation of the local immune responses in the lung of HIV-1-infected patients
5. CD8 T-cell infiltration in extravascular tissues of patients with human immunodeficiency virus infection: Interleukin-15 upmodulates costimulatory pathways involved in the antigen-presenting cells-T-cell interaction
6. Chemokines
7. Chemokines-chemotactic cytokines that mediate inflammation
8. Recent advances in chemokines and chemokine receptors
9. Chemotactic cytokines: From the molecular level to clinical use
10. Mig and IP-10: CXC chemokines that target lymphocytes
11. Production of interferon-gamma by lung lymphocytes in HIV-infected individuals
12. Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling
13. Involvement of the IP-10 chemokine in sarcoid granulomatous reactions
14. The T cell-specific CXC chemokines IP-10, Mig, and I-TAC are expressed by activated human bronchial epithelial cells
15. Technical recommendations and guidelines for bronchoalveolar lavage (BAL). Report of the European Society of Pneumology Task Group on BAL
16. The expanding universe of T-cell subsets: Th1, Th2, and more
17. IL-15 induces the expression of chemokines and their receptors in T lymphocytes
18. Interleukin-15 triggers activation and growth of the CD8 T-cell pool in extravascular tissues of patients with acquired immunodeficiency syndrome
19. Chemoattractant factors (IP-10, MIP-1alpha, IL-16) mRNA expression in mononuclear cells from different tissues during acute SIVmac251 infection of macaques
20. RANTES, IFN-gamma, CCR1, and CCR5 mRNA expression in peripheral blood, lymph node, and bronchoalveolar lavage mononuclear cells during primary simian immunodeficiency virus infection of macaques
21. Skewing of the T-cell receptor repertoire in the lung of patients with HIV-1 infection
22. Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells in vitro and in the SCID mouse-human rheumatoid arthritis model in vivo
23. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions
24. CCR5+ and CXCR3+ T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesions
25. Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15
26. Human IP-10 selectively promotes dominance of polyclonally activated and environmental antigen-driven IFN-gamma over IL-4 responses
27. CD8+ T lymphocytes in the lung of acquired immunodeficiency syndrome patients harbor human immunodeficiency virus type 1
28. HIV load in highly purified CD8+ T cells retrieved from pulmonary and blood compartments
29. Mechanism of human immunodeficiency virus type 1 localization in CD4-negative thymocytes: Differentiation from a CD4-positive precursor allows productive infection
30. Tissue infiltration in a CD8 lymphocytosis syndrome associated with human immunodeficiency virus-1 infection has the phenotypic appearance of an antigenically driven response
31. Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors