Calcium-mediated proteolytic damage in white matter of hydrocephalic rats?

Journal of Neuropathology and Experimental Neurology

Volumn 59, Issue 11, 2000, Pages 946-954

  Del Bigio, Marc R ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Axon; Calpain; Hydrocephalus; Kaolin; Proteolytic enzyme

Indexed keywords

CALCIUM ION; CALPAIN; GLYOXAL DERIVATIVE; KAOLIN; PROTEINASE; SPECTRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; CALCIUM SIGNALING; CISTERNA MAGNA; CONTROLLED STUDY; ENZYME ACTIVITY; HISTOPATHOLOGY; HYDROCEPHALUS; IMMUNOBLOTTING; IMMUNOREACTIVITY; NERVE FIBER; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; SIGNAL TRANSDUCTION; WHITE MATTER;

EID: 0033767375     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/59.11.946     Document Type: Article

References (59)

1. Hydrocephalus-induced changes in the composition of cerebrospinal fluid
2. Neuropathological changes caused by hydrocephalus
3. Neonatal hydrocephalus. Mechanisms and consequences
4. Characterization of a distinct set of intraaxonal ultrastructural changes associated with traumatically induced alteration in axolemmal permeability
5. The role of calpain-mediated spectrin proteolysis in traumatically induced axonal injury
6. Mechanisms of calpain proteolysis following traumatic brain injury: Implications for pathology and therapy: A review and update
7. Traumatically induced axonal injury: Pathogenesis and pathobiological implications
8. Are the pathobiological changes evoked by traumatic brain injury immediate and irreversible?
9. Focal axonal injury: The early axonal response to stretch
10. Correlation between electrophysiological effects of mexiletine and ischemic protection in central nervous system white matter
11. Anoxic and ischemic injury of myelinated axons in CNS white matter: From mechanistic concepts to therapeutics
12. Axonal injury caused by focal cerebral ischemia in the rat
13. Magnetic resonance imaging and behavioral analysis of immature rats with kaolin-induced hydrocephalus: Pre- and post-shunting observations
14. Animal models of hydrocephalus: Recent developments
15. Altered diffusion and perfusion in hydrocephalic rat brain: A magnetic resonance imaging analysis
16. Miscellaneous methods
17. Calcium phosphate in osteogenic cells. A critique of the glyoxal bis (2-hydroxyanil) and the dilute silver acetate methods
18. The applicability of a new Schiff base, glyoxal bis (2-hydroxyanil), for the cytochemical localization of ionic calcium
19. Growth associated protein-43 is increased in cerebrum of immature rats following induction of hydrocephalus
20. Protein measurement with the Folin phenol reagent
21. Rapid calpain I activation and cytoskeletal protein degradation following traumatic spinal cord injury: Attenuation with riluzole pretreatment
22. Increased immunoreactivity of brain spectrin in Alzheimer disease: A marker for synapse loss?
23. Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain
24. Cell death, axonal damage, and cell birth in the immature rat brain following induction of hydrocephalus
25. Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates
26. Myelination delay in the cerebral white matter of immature rats with kaolin-induced hydrocephalus is reversible
27. A calpain inhibitor attenuates cortical cytoskeletal protein loss after experimental traumatic brain injury in the rat
28. Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin
29. μ-calpain activation and calpain-mediated cytoskeletal proteolysis following traumatic brain injury
30. Prolonged calpain-mediated spectrin breakdown occurs regionally following experimental brain injury in the rat
31. Evaluation of the glyoxal-bis-(2-hydroxyanil)-method for staining of calcium in model gelatin films and pancreatic islets
32. Calcium, zinc and other elements in islet and exocrine tissue of the rat pancreas as measured by histochemical methods and electron-probe microanalysis. Effects of fasting and tolbutamide
33. Calcium in ischemic cell death
34. Normal and abnormal calcium homeostasis in neurons: A basis for the pathophysiology of traumatic and ischemic central nervous system injury
35. The ependyma: A protective barrier between brain and cerebrospinal fluid
36. Ependyma: Normal and pathological. A review of the literature
37. Do brain fluid ion concentrations change in hydrocephalus? A study on potassium and calcium in rats with congenital hydrocephalus
38. Mechanism of calcium entry during axon injury and degeneration
39. Axotomy-induced axonal degeneration is mediated by calcium influx through ion-specific channels
40. Cytochemical evidence for redistribution of membrane pump calcium-ATPase and ecto-Ca-ATPase activity, and calcium influx in myelinated nerve fibres of the optic nerve after stretch injury
41. Glial calcium: Homeostasis and signaling function
42. Calpain inhibitors as potential treatment for stroke and other neurodegenerative diseases: Recent trends and developments
43. The calpain proteolytic system in neonatal hypoxic-ischemia
44. Immunoblot analyses of the relative contributions of cysteine and aspartic proteases to neurofilament breakdown products following experimental brain injury in rats
45. Lesions of entorhinal cortex produce a calpain-mediated degradation of brain spectrin in dentate gyrus. I. Biochemical studies
46. Dual response of calpain to rat brain postdecapitative ischemia
47. Resealing of transected myelinated mammalian axons in vivo: Evidence for involvement of calpain
48. The localization of mcalpain in myelin: Immunocytochemical evidence in different areas of rat brain and nerves
49. Structure and physiology of calpain, an enigmatic process
50. Increased intracellular calpain detection in experimental focal cerebral ischemia
51. Altered gene expression for calpain/calpastatin system in motor neuron degeneration (Mnd) mutant mouse brain and spinal cord
52. Proteolytic activity is altered in brain tissue of rats upon chronic exposure to ozone
53. Diverse stimuli induce calpain overexpression and apoptosis in C6 glioma cells
54. Effects of brief starvation on brain protease activity
55. Effect of mu-calpain on m-calpain
56. A mechanistic analysis of nondisruptive axonal injury: A review
57. Calpain activation and cytoskeletal protein breakdown in the corpus callosum of head-injured patients
58. Surgical management of neonatal hydrocephalus
59. Medical management of neonatal posthemorrhagic hydrocephalus