Antigen presentation in the lung

American Journal of Respiratory and Critical Care Medicine

Volumn 162, Issue 4 II, 2000, Pages

  Holt, Patrick G ^a,b  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; STEROID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; CONFERENCE PAPER; DENDRITIC CELL; DISEASE PREDISPOSITION; IMMUNE RESPONSE; IMMUNOMODULATION; INFLAMMATORY DISEASE; LUNG; NEUROSECRETORY CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

EID: 0033763038     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.162.supplement_3.15tac2     Document Type: Conference Paper

References (50)

1. Ia-positive dendritic cells form a tightly meshed network within the human airway epithelium
2. + (T6), HLA-DR-expressing cells, presumably Langerhans cells, in nasal mucosa
3. Studies on the density, distribution, and surface pheontype of intraepithelial class II major histocompatibility complex antigen (Ia)-bearing dendritic cells (DC) in the conducting airways
4. MHC class II antigen-bearing dendritic cells in pulmonary tissues of the rat: Regulation of antigen presentation activity by endogenous macrophage populations
5. Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages
6. Defective regional immunity in the respiratory tract of neonates is attributable to hyporesponsiveness of local dendritic cells to activation signals
7. Characterization of accessory molecules in murine lung dendritic cell function: Roles for CD80, CD86, CD54, and CD40L
8. Resting respiratory tract dendritic cells preferentially stimulate Th2 responses and require obligatory cytokine signals for induction of Th1 immunity
9. Human lung dendritic cells have an immature phenotype with efficient mannose receptors
10. Origin and steady-state turnover of class II MHC-bearing dendritic cells in the epithelium of the conducting airways
11. Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces
12. Inflammatory infiltration of the upper airway epithelium during Sendai virus infection: Involvement of epithelial dendritic cells
13. Dendritic cells are recruited into the airway epithelium during the inflammatory response to a broad spectrum of stimuli
14. The antigen-presenting activities of Ia+ dendritic cells shift dynamically from lung to lymph node after an airway challenge
15. Interstitial lung macrophages interact with dendritic cells to present antigenic peptides derived from particulate antigens to T cells
16. Ontogeny of Ia+ accessory cells in fetal newborn rat lung
17. Regulation of the immunostimulatory activity of rat pulmonary interstitial dendritic cells by cell-cell interactions and cytokines
18. Comparison of lung dendritic cells and B cells in stimulating naive antigen-specific T cells
19. The dendritic cell system and its role in immunogenicity
20. The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class II-restricted CD4+ T cell-dependent immune deviation resulting in selective suppression of IgE production
21. Cytokine modulation of the immunosuppressive phenotype of pulmonary alveolar macrophages via regulation of nitric oxide production
22. Macrophage-derived nitric oxide regulates T-cell activation via reversible disruption of the Jak3/Stat5 signalling pathway
23. Alveolar macrophages from humans and rodents selectively inhibit T-cell proliferation but permit T-cell activation and cytokine secretion
24. Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice
25. Regulation of IgE production in presensitised animals: In vivo elimination of alveolar macrophages preferentially increases IgE responses to inhaled allergen
26. Modulation of airway intraepithelial dendritic cells following exposure to steroids
27. Increased numbers of dendritic cells in the bronchial mucosa of atopic asthmatic patients: Downregulation by inhaled corticosteroids
28. Airway inflammation in asthma and chronic obstructive pulmonary disease with special emphasis on the antigen-presenting dendritic cell: Influence of treatment with fluticasone propionate
29. Beta2-antagonists prevent Th1 development by selective inhibition of interleukin 12
30. Accumulation of Langerhans' cells on the epithelial surface of the lower respiratory tract in normal subjects in association with cigarette smoking
31. Cigarette smoking-induced changes in the number and differentiated state of pulmonary dendritic cells/Langerhans cells
32. Dendritic cells and macrophages in lung allografts: A role in chronic rejection?
33. Antigen presenting cells in the nasal mucosa of patients with allergic rhinitis during allergen provocation
34. Fluctuation of the number of CD-1 (T6)-positive dendritic cells, presumably Langerhans cells, in the nasal mucosa of patients with an isolated grass-pollen allergy before, during, and after the grass-pollen season
35. Dendritic cells in normal and asthmatic airways: Expression of the α subunit of the high affinity immunoglobulin E receptor (FcεRI-α)
36. The role of allergy in the development of asthma
37. Immunohistochemical characterisation of the cellular infiltration in asthmatic bronchi
38. Dendritic cells are required for the development of chronic eosinophilic airway inflammation in response to inhaled antigen in sensitized mice
39. GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice
40. Regulation of rat pulmonary dendritic cell immunostimulatory activity by alveolar epithelial cell-derived granulocyte macrophage colony-stimulating factor
41. Immunological/physiological relationships in asthma: Potential regulation by lung macrophages
42. Alveolar macrophage accessory cell function in bronchial asthma
43. Development of the airway intraepithelial dendritic cell network in the rat from class II MHC (Ia) negative precursors: Differential regulation of Ia expression at different levels of the respiratory tract
44. Development of long term tolerance versus sensitisation to environmental allergens during the perinatal period
45. Transplacental priming of the human immune system to environmental allergens: Universal skewing of initial T-cell responses towards the Th-2 cytokine profile
46. Development of allergen-specific T-cell memory in atopic and normal children
47. Th-2-polarised immunological memory to inhalant allergens in atopics is established during infancy and early childhood
48. Regulation of Th-cell responses to inhalant allergen during early childhood
49. The inflammation-repair cycle in asthma: The pivotal role of the airway epithelium
50. Pulmonary response to inhaled antigen: Neuroimmune interactions promote the recruitment of dendritic cells to the lung and the cellular immune response to inhaled antigen