Dendritic cells are recruited into the airway epithelium during the inflammatory response to a broad spectrum of stimuli

Journal of Experimental Medicine

Volumn 184, Issue 6, 1996, Pages 2429-2432

  McWilliam, Andrew S ^a   Napoli, Sylvia ^a   Marsh, Amanda M ^a   Pemper, Francis L ^a   Nelson, Delia J ^a   Pimm, Carolyn L ^a   Stumbles, Philip A ^a   Wells, Timothy N C ^a,b   Holt, Patrick G ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; CHEMOATTRACTANT; CHEMOKINE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; OVALBUMIN; VIRUS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; CHEMOTAXIS; CONTROLLED STUDY; DENDRITIC CELL; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY EPITHELIUM; SENSITIZATION; VIRUS INFECTION;

ANIMALS; ANTIGENS; BORDETELLA PERTUSSIS; CHEMOKINES; DENDRITIC CELLS; EPITHELIUM; INFLAMMATION; MORAXELLA (BRANHAMELLA) CATARRHALIS; MUCOUS MEMBRANE; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEISSERIACEAE INFECTIONS; OVALBUMIN; RATS; RATS, INBRED STRAINS; RESPIRATORY TRACT INFECTIONS; RESPIROVIRUS; RESPIROVIRUS INFECTIONS; T-LYMPHOCYTES; WHOOPING COUGH;

EID: 0030458141     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.184.6.2429     Document Type: Article

References (15)

1. Janeway, C.A. 1992. The immune response evolved to discriminate infectious nonself from noninfectious self. Immunol. Today. 13:11-16.
2. Steinman, R.M. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9:271-296.
3. Holt, P.G., M.A. Schon-Hegrad, and J. Oliver. 1988. MHC class II antigen-bearing dendritic cells in pulmonary tissues of the rat: regulation of antigen presentation activity by endogenous macrophage populations. J. Exp. Med. 167:262-274.
4. Schon-Hegrad, M.A., J. Oliver, P.G. McMenamin, and P.G. Holt. 1991. Studies on the density, distribution, and surface phenotype of intraepithelial class II MHC antigen (Ia)-bearing dendritic cells (DC) in the conducting airways. J. Exp. Med. 173:1345-1356.
5. Hart, D.N.J, and J.W. Fabre. 1981. Demonstration and characterization of Ia-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues, but not brain J. Exp. Med. 154:347-361.
6. Chen, H.-D., C. Ma, J.-T. Yuan, Y.-K. Wang, and W.K. Silvers. 1986. Occurrence of donor Langerhans cells in mouse and rat chimeras and their replacement in skin grafts. J. Invest. Dermatol. 86:630-633.
7. Possum, S. 1989. Dendritic leukocytes: features of their in vivo physiology. Res. Immunol. 140:883-891.
8. Holt, P.G., S. Haining, D.J. Nelson, and J.D. Sedgwick. 1994. Origin and steady-state turnover of class II MHC-bearing dendritic cells in the epithelium of the conducting airways. J. Immunol. 153:256-261.
9. Mason, D.W., R.P. Arthur, M.J. Dallman., J.R. Green., G.P. Spickett, and M.L. Thomas. 1983. Functions of rat T-lymphocyte subsets isolated by means of monoclonal antibodies. Immunol. Rev. 74:57-82.
10. Hünig, T., H.J. Wallny, J.K. Hartley, A. Lawetzky, and G. Tiefenthaler. 1989. A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes. J. Exp. Med. 169:73-86.
11. Damoiseaux, J.G., E.A. Dopp, J.J. Neefjes, R.H. Beelen, and C.D. Dijkstra. 1989. Heterogeneity of macrophages in the rat evidenced by variability in determinants: two new anti-rat macrophage antibodies against a heterodimer of 160 and 95 kd (CD11/CD18). J. Leukocyte Biol. 46:556-564.
12. Sekiya, S., S. Gotoh, T. Yamashita, T. Watanabe, S. Saitoh, and F. Sendo. 1989. Selective depletion of rat neutrophils by in vivo administration of a monoclonal antibody. J. Leukocyte Biol. 46:96-102.
13. McWilliam, A.S., D. Nelson, J.A. Thomas, and P.G. Holt. 1994. Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces. J. Exp. Med. 179:1331-1336.
14. Sozzani, S., F. Sallusto, W. Luini, D. Zhou, L. Piemonti, P. Allavena, J. Van Damme, S. Valitutti, A. Lanzavecchia, and A. Mantovani. 1995. Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines. J. Immunol. 155:3292-3295.
15. Ibrahim, M.A.A., B.M. Chain, and D.R. Katz. 1995. The injured cell: the role of the dendritic cell system as a sentinel receptor pathway. Immunol. Today. 16:181-186.