The deficit syndrome and eye tracking disorder may reflect distinct subtype within the syndrome of schizophrenia

Schizophrenia Bulletin

Volumn 26, Issue 4, 2000, Pages 855-866

  Ross, David E ^a,b  

^a MARYLAND PSYCHIATRIC RESEARCH CENTER   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Deficit syndrome; Eye movements; Schizophrenia; Smooth pursuit

Indexed keywords

ARTICLE; COGNITION; EYE MOVEMENT DISORDER; HUMAN; MENTAL DISEASE; NEGATIVE SYNDROME; PATHOPHYSIOLOGY; PERFORMANCE; PRIORITY JOURNAL; RISK FACTOR; SCHIZOPHRENIA; SMOOTH PURSUIT EYE MOVEMENT;

EID: 0033762733     PISSN: 05867614     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.schbul.a033500     Document Type: Article

References (108)

1. Parallel organization of functionally segregated circuits linking basal ganglia and cortex
2. Awareness of illness in schizophrenia and schizoaffective and mood disorders
3. The Scale for the Assessment of Negative Symptoms (SANS): Conceptual and theoretical foundations
4. Schizophrenia susceptibility and chromosome 6p24-22
5. Eye tracking dysfunction is a putative phenotypic susceptibility marker of schizophrenia and maps to a locus on chromosome 6p in families with multiple occurrence of the disease
6. Smooth pursuit eye tracking, neuropsychological test performance, and computed tomography in schizophrenia
7. Smooth pursuit eye tracking and neuro-psychological performance in healthy volunteers: Exploring a possible genetic marker for vulnerability to schizophrenia
8. Auditory P300 and eye tracking dysfunction in schizophrenic pedigrees
9. Magnetic resonance imaging in schizophrenia: Altered brain morphology associated with P300 abnormalities and eye tracking dysfunction
10. Effects of clozapine on positive and negative symptoms in outpatients with schizophrenia
11. Structural abnormalities in deficit and nondeficit schizophrenia
12. Domains of psychopathology: An approach for the reduction of heterogeneity in schizophrenia
13. Clinical correlates of the deficit syndrome of schizophrenia
14. Neuropsychological impairments in deficit vs. non-deficit forms of schizophrenia
15. The neurological evaluation scale (NES): A structured instrument for the assessment of neurological signs in schizophrenia
16. Attentional impairments in deficit and nondeficit forms of schizophrenia
17. Visual information-processing impairments in deficit and nondeficit schizophrenia
18. Strong inference, theory, testing and the neuroanatomy of schizophrenia
19. Deficit and nondeficit forms of schizophrenia: The concept
20. Pursuit eye movements in chronic schizophrenics: Relationship between increased saccades and negative symptoms
21. Smooth-pursuit eye movement dysfunction and liability for schizophrenia: Implications for genetic modeling
22. Pursuit gain and saccadic intrusions in first degree relatives of probands with schizophrenia
23. An experimental study of the ocular reactions of the insane from photographic records
24. Family history and deficit form in schizophrenia
25. Antecedents, symptom progression, and long-term outcome of the deficit syndrome in schizophrenia
26. Testing systems for assessment of negative symptoms in schizophrenia
27. Infants at risk for schizophrenia: Sequelae of a genetic neurointegrative defect. A review and replication analysis of pandysmaturation in the Jerusalem Infant Development Study
28. Relationship between smooth pursuit eye-tracking and cognitive performance in schizophrenia
29. Smooth pursuit eye movements and neuropsychological tests in schizophrenic patients: Possible involvement of attentional components
30. Linkage analyses of schizophrenia to chromosome 6p24-p22: An attempt to replicate
31. Mixture distributions in psychiatric research
32. Familial prevalence and coaggregation of schizotypy indicators: A multitrait family study
33. Schizophrenia susceptibility and chromosome 6p24-22
34. Significance and meaning of neurological signs in schizophrenia
35. Deviant eye tracking in twins discordant for psychosis: A replication
36. Abnormal-pursuit eye movements in schizophrenia: Evidence for a genetic indicator
37. A single dominant gene can account for eye tracking dysfunctions and schizophrenia in offspring of discordant twins
38. Smooth pursuit eye tracking in twins: A critical commentary
39. Eye-tracking patterns in schizophrenia
40. Eye-tracking dysfunctions in schizophrenic patients and their relatives
41. Pursuit eye movement dysfunctions in schizophrenia: Family evidence for specificity
42. Electro-oculographic recording and scoring of smooth pursuit and saccadic eye tracking: A parametric study using monozygotic twins
43. Eye tracking and psychopathology: New procedures applied to a sample of normal monozygotic twins
44. Smooth-pursuit eye tracking in first-episode psychotic patients and their relatives
45. Clinical, neuropsychological, and brain structural correlates of smooth-pursuit eye tracking performance in chronic schizophrenia
46. The Positive and Negative Syndrome Scale (PANSS): Rationale and Standardization
47. Eye tracking, schizophrenic symptoms, and schizotypal personality disorder
48. Eye tracking, attention, and schizotypal symptoms in nonpsychotic relatives of patients with schizophrenia
49. Smooth pursuit eye tracking dysfunction and negative symptoms in schizophrenia
50. The structure of schizotypy: A pilot multitrait twin study
51. The clinical correlates of neurological soft signs in chronic schizophrenia
52. The deficit syndrome in the DSM-IV Field Trial: I. Alcohol and other drug abuse
53. The deficit syndrome in the DSM-IV Field Trial: II. Depressive episodes and persecutory beliefs
54. Case identification and stability of the deficit syndrome of schizophrenia
55. Depressive symptoms and the deficit syndrome of schizophrenia
56. The Schedule for the Deficit Syndrome: An instrument for research in schizophrenia
57. Summer birth and the deficit syndrome of schizophrenia
58. The deficit syndrome in the Suffolk County Mental Health Project
59. Comparison of efficacy of social skills training for deficit and nondeficit negative symptoms in schizophrenia
60. Eye tracking in relation to age, sex, and illness
61. Blood flow activation differences during an auditory task in schizophrenic patients with and without primary negative symptoms
62. Attentional and eye tracking deficits correlate with negative symptoms in schizophrenia
63. Normal eye tracking is associated with abnormal morphology of medial temporal lobe structures in schizophrenia
64. Eye tracking dysfunction and schizophrenia: A critical perspective
65. Relatives of unipolar and b polar patients have normal pursuit
66. Brain morphology, dopamine and eye tracking in first episode schizophrenia: Prevalence and clinical correlates
67. Correlation of Wisconsin Card Sorting Test performance with eye tracking in schizophrenia
68. A quantitative analysis of smooth pursuit eye tracking in monozygotic twins discordant for schizophrenia
69. Saccadic reaction times in acute and remitted schizophrenics
70. Children at risk for schizophrenia: The Jerusalem Infant Development Study: II. Neurobehavioral deficits at school age
71. Eye movements of teenage child ten of schizophrenics: A possible inherited marker of susceptibility to the disease
72. The deficit state in first-episode schizophrenia
73. An international two-stage genome-wide search for schizophrenia susceptibility genes
74. Schizophrenia susceptibility and chromosome 6p24-22
75. The Brief Psychiatric Rating Scale in psychopharmacologic research
76. Association of working memory deficit and eye tracking dysfunction in schizophrenia
77. No evidence for linkage of chromosome 6p markers to schizophrenia in Southern African Bantu-speaking families
78. Eye-tracking dysfunction in offspring from the New York High-Risk Project: Diagnostic specificity and the role of attention
79. Association between eye tracking disorder in schizophrenia and poor sensory integration
80. Mixture analysis of smooth pursuit eye movements in schizophrenia
81. Eye tracking disorder in schizophrenia is characterized by specific ocular motor defects and is associated with the deficit syndrome
82. Specific measures account for most of the variance in qualitative ratings of smooth pursuit eye movements in schizophrenia
83. Association of abnormal smooth pursuit eye movements with the deficit syndrome in schizophrenic patients
84. Abnormal smooth pursuit eye movements in schizophrenic patients are associated with cerebral glucose metabolism in oculomotor regions
85. Early expression of smooth-pursuit eye movement abnormalities in children of schizophrenic parents
86. Neurological soft signs in schizophrenia
87. Neurological abnormalities in patients with schizophrenia or schizophreniform disorder at first admission to hospital: Correlations with computerized tomography and regional cerebral blood flow findings
88. Neurological examination abnormalities in neuroleptic-naive patients with first-break schizophrenia: Preliminary results
89. Additional support for schizophrenia linkage on chromosomes 6 and 8: A multicenter study
90. Evaluation of a susceptibility gene for schizophrenia on chromosome 6p by multipoint affected sib-pair linkage analysis
91. Deficits in sensory gating in schizophrenic patients and their relatives: Evidence obtained with auditory evoked responses
92. Impaired smooth pursuit eye movement: Vulnerability marker for schizotypal personality disorder in a normal volunteer population
93. Clinical, psychophysiological, and neurological characteristics of volunteers with impaired smooth pursuit eye movements
94. Eye movement impairment and schizotypal psychopathology
95. Smooth pursuit eye tracking impairment: Relation to other 'markers' of schizophrenia and psychological correlates
96. Eye tracking impairment in clinically identified patients with schizotypal personality disorder
97. A potential vulnerability locus for schizophrenia on chromosome 6p24-22: Evidence for genetic heterogeneity
98. Mixture analysis of pursuit eye-tracking dysfunction in schizophrenia
99. Eye tracking dysfunction in schizophrenia: Characterization of component eye movement abnormalities, diagnostic specificity and the role of attention
100. Limbic system abnormalities identified in schizophrenia using positron emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome
101. Oculomotor abnormalities and their clinical correlates in schizophrenia
102. Smooth pursuit eye movements to extraretinal motion signals: Deficits in relatives of patients with schizophrenia
103. Eye tracking impairment: Attentional and psychometric correlates in psychiatric patients
104. Phenomenological correlates of metabolic activity in 18 patients with chronic schizophrenia
105. Borna disease virus antibodies and the deficit syndrome of schizophrenia