Kinetics of drug metabolism in rat liver slices: IV. Comparison of ethoxycoumarin clearance by liver slices, isolated hepatocytes, and hepatic microsomes from rats pretreated with known modifiers of cytochrome P-450 activity

Drug Metabolism and Disposition

Volumn 27, Issue 4, 1999, Pages 526-532

  Carlile, David J ^a   Hakooz, Nancy ^a   Houston, J Brian ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHOXYCOUMARIN DEETHYLASE; BETA NAPHTHOFLAVONE; CYTOCHROME P450; ETHOXYCOUMARIN; PHENOBARBITAL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; ENZYME ACTIVITY; LIVER CELL; LIVER METABOLISM; LIVER MICROSOME; LIVER SLICE; MALE; METABOLIC RATE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BETA-NAPHTHOFLAVONE; CELL SEPARATION; COUMARINS; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME ACTIVATION; ENZYME INHIBITORS; KINETICS; LIVER; MALE; MICROSOMES, LIVER; PHENOBARBITAL; RATS; RATS, SPRAGUE-DAWLEY; TRIAZOLES;

ANIMALIA;

EID: 0032919386     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

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