SOS and Mayday: Multiple inducible mutagenic pathways in Escherichia coli

Molecular Microbiology

Volumn 30, Issue 5, 1998, Pages 905-910

  Humayun, M Zafri ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIFAMPICIN; STREPTOMYCIN;

DNA DAMAGE; DNA REPAIR; DNA REPLICATION; ENVIRONMENT; ESCHERICHIA COLI; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RECA GENE; REVIEW; RNA TRANSLATION; STRESS; ULTRAVIOLET RADIATION;

BACTERIAL PROTEINS; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MUTAGENESIS; PROTEIN BIOSYNTHESIS; REC A RECOMBINASES; SOS RESPONSE (GENETICS); ULTRAVIOLET RAYS;

ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0031739299     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1998.01120.x     Document Type: Review

References (39)

1. Bailone, A., Sommer, S., Knezevic, J., and Devoret, R. (1991) A RecA protein deficient in its interaction with the UmuDC complex. Biochimie 73: 479-484.
2. Boe, L. (1992) Translational errors as the cause of mutations in Escherichia coli. Mol Gen Genet 231: 469-471.
3. Bridges, B.A., and Timms, A.R. (1997) Mutation in Escherichia coli under starvation conditions: a new pathway leading to small deletions in strains defective in mismatch correction. EMBO J 16: 3349-3356.
4. Brotcorne-Lannoye, A., and Maenhaut-Michel, G. (1986) Role of RecA protein in untargeted UV mutagenesis of bacteriophage lambda: evidence for the requirement for the dinB gene. Proc Natl Acad Sci USA 83: 3904-3908.
5. Bruck, I., Woodgate, R., McEntee, K., and Goodman, M.F. (1996) Purification of a soluble UmuD′C complex from Escherichia coli. Cooperative binding of UmuD′C to single-stranded DNA. J Biol Chem 271: 10767-10774.
6. Cairns, J. (1998) Mutation and cancer: the antecedents to our studies of adaptive mutation. Genetics 148: 1433-1440.
7. Christensen, J.R., LeClerc, J.E., Valone, T.P., Christensen, R.B., and Lawrence, C.W. (1988) UmuC function is not essential for the production of all targeted lad mutations induced by ultraviolet light. J Mol Biol 203: 635-641.
8. Connolly, D.M., and Winkler, M.E. (1989) Genetic and physiological relationships among the miaA gene, 2-methylthio-N6-(delta 2-isopentenyl)-adenosine tRNA modification, and spontaneous mutagenesis in Escherichia coli K-12. J Bacteriol 171: 3233-3246.
9. Connolly, D.M., and Winkler, M.E. (1991) Structure of Escherichia coli K-12 miaA and characterization of the mutator phenotype caused by miaA insertion mutations. J Bacteriol 173: 1711-1721.
10. Fijalkowska, I.J., Dunn, R.L., and Schaaper, R.M. (1997) Genetic requirements and mutational specificity of the Escherichia coli SOS mutator activity. J Bacteriol 179: 7435-7445.
11. Foster, P.L. (1998) Adaptive mutation: has the unicorn landed? Genetics 148: 1453-1459.
12. Friedberg, E.C., Walker, G.C., and Siede, W. (1995) DNA Repair and Mutagenesis. Washington, DC: American Society for Microbiology Press.
13. Hall, B.G. (1998) Adaptive mutagenesis at ebgR is regulated by PhoPQ. J Bacteriol 180: 2862-2865.
14. Kim, S.R., Maenhaut-Michel, G., Yamada, M., Yamamoto, Y., Matsui, K., Sofuni, T., et al. (1997) Multiple pathways for SOS-induced mutagenesis in Escherichia coli: an over-expression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA. Proc Natl Acad Sci USA 94: 13792-13797.
15. Kulaeva, O.I., Koonin, E.V., McDonald, J.P., Randall, S.K., Rabinovich, N., Connaughton, J.F., et al. (1996) Identification of a DinB/UmuC homolog in the archeon Sulfolobus solfataricus. Mutat Res 357: 245-253.
16. Kunz, B.A., Kohalmi, S.E., Kunkel, T.A., Mathews, C.K., Mcintosh, E.M., and Reidy, J.A. (1994) Deoxynucleoside triphosphate levels: a critical factor in the maintenance of genetic stability. Mutat Res 318: 1-64.
17. Lackey, D., Krauss, S.W., and Linn, S. (1985) Characterization of DNA polymerase I*, a form of DNA polymerase I found in Escherichia coli expressing SOS functions. J Biol Chem 260: 3178-3184.
18. Livneh, Z., Cohen-Fix, O., Skaliter, R., and Elizur, T. (1993) Replication of damaged DNA and the molecular mechanism of ultraviolet light mutagenesis. Crit Rev Biochem Molec Biol 28: 465-513.
19. McDonald, J.P., Levine, A.S., and Woodgate, R. (1997) The Saccharomyces cerevisiae RAD30 gene, a homologue of Escherichia coli dinB and umuC, is DNA damage inducible and functions in a novel error-free postreplication repair mechanism. Genetics 147: 1557-1568.
20. Michaels, M.L., Cruz, C., and Miller, J.H. (1990) mutA and mutC: two mutator loci in Escherichia coli that stimulate transversions. Proc Natl Acad Sci USA 87: 9211-9215.
21. Moses, R.E., Byford, A., and Hejna, J.A. (1992) Replisome pausing in mutagenesis. Chromosoma 102: 5157-5160.
22. Murphy, H.S., and Humayun, M.Z. (1997) Escherichia coli cells expressing a mutant glyV (glycine tRNA) gene have a UVM-constitutive phenotype: implications for mechanisms underlying the mutA or mutC mutator effect. J Bacteriol 179: 7507-7514.
23. Murphy, H.S., Palejwala, V.A., Rahman, M.S., Dunman, P.M., Wang, G., and Humayun, M.Z. (1996) Role of mismatch repair in the Escherichia coli UVM response. J Bacteriol 178: 6651-6657.
24. Nair, J., Vaca, C.E., Velic, I., Mutanen, M., Valsta, L.M., and Bartsch, H. (1997) High dietary omega-6 polyunsaturated fatty acids drastically increase the formation of etheno-DNA base adducts in white blood cells of female subjects. Cancer Epidemiol Biomarkers Prev 6: 597-601.
25. Napolitano, R.L., Lambert, I.B., and Fuchs, R.P. (1997) SOS factors involved in translesion synthesis. Proc Natl Acad Sci USA 94: 5733-5738.
26. Ohmori, H., Hatada, E., Qiao, Y., Tsuji, M., and Fukuda, R. (1995) dinP, a new gene in Escherichia coli, whose product shows similarities to UmuC and its homologues. Mutat Res 347: 1-7.
27. Opperman, T., Murli, S., and Walker, G.C. (1996) The genetic requirements for UmuDC-mediated cold sensitivity are distinct from those for SOS mutagenesis. J Bacteriol 178: 4400-4411.
28. Palejwala, V.A., Rzepka, R.W., and Humayun, M.Z. (1993) UV irradiation of Escherichia coli modulates mutagenesis at a site-specific ethenocytosine residue on M13 DNA. Evidence for an inducible recA-independent effect. Biochemistry 32: 4112-4120.
29. Palejwala, V.A., Wang, G., Murphy, H.S., and Humayun, M.Z. (1995) Functional recA, lexA, umuD, umuC, polA, and polB genes are not required for the Escherichia coli UVM response. J Bacteriol 177: 6041-6048.
30. Qiu, Z., and Goodman, M.F. (1997) The Escherichia coli polB locus is identical to dinA, the structural gene for DNA polymerase II. Characterization of Pol II purified from a polB mutant. J Biol Chem 272: 8611-8617.
31. Rahman, M.S., Dunman, P.M., Wang, G., Murphy. H.S., and Humayun, M.Z. (1996) Effect of UVM induction on mutation fixation at non-pairing and mispairing DNA lesions. Mol Microbiol 22: 747-755.
32. Rajagopalan, M., Lu, C., Woodgate, R., O'Donnell, M., Goodman, M.F., and Echols, H. (1992) Activity of the purified mutagenesis proteins UmuC, UmuD′ and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. Proc Natl Acad Sci USA 89: 10777-10781.
33. Rosenberg, S.M., Thulin, C., and Harris, R.S. (1998) Transient and heritable mutators in adaptive evolution in the lab and in nature. Genetics 148: 1559-1566.
34. Slupksa, M.M., Baikalov, C., Lloyd, R., and Miller, J.H. (1996) Mutator tRNAs are encoded by the Escherichia coli mutator genes mutA and mutC: a novel pathway for mutagenesis. Proc Natl Acad Sci USA 93: 4380-4385.
35. Smith, B.T., and Walker. G.C. (1998) Mutagenesis and More: umuDC and the Escherichia coli SOS Response. Genetics 148: 1599-1610.
36. Sommer, S., Knezevic, J., Bailone, A., and Devoret, R. (1993) Induction of only one SOS operon, umuDC, is required for SOS mutagenesis in Escherichia coli. Mol Gen Genet 239: 137-144.
37. Sweasy, J.B., Witkin, E.M., Sinha, N., and Maniscalco, V.R. (1990) RecA protein of Escherichia coli has a third essential role in SOS mutator activity. J Bacteriol 172: 3030-3036.
38. Taddei, F., Halliday, J.A., Matic, I., and Radman, M. (1997) Genetic analysis of mutagenesis in aging Escherichia coli colonies. Mol Gen Genet 256: 277-281.
39. Wandt, G., Kubis, S., and Quinones, A. (1997) Treatment with DNA-damaging agents increases expression of polA′-′lacZ gene fusions in Escherichia coli K-12. Mol Gen Genet 254: 98-103.