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Volumn 12, Issue 1, 2000, Pages 41-50
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The role of P-glycoprotein in determining the oral absorption and clearance of the NK2 antagonist, UK-224,671
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Author keywords
Oral absorption; P glycoprotein; Transgenic mice; UK 224,671
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Indexed keywords
CYTOCHROME P450 ISOENZYME;
GLYCOPROTEIN P;
NEUROKININ 2 RECEPTOR ANTAGONIST;
UK 224671;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ANIMAL EXPERIMENT;
ARTICLE;
CELL STRAIN CACO 2;
CONTROLLED STUDY;
DRUG ABSORPTION;
DRUG BIOAVAILABILITY;
DRUG CLEARANCE;
DRUG EXCRETION;
DRUG METABOLISM;
EPITHELIUM CELL;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
INTESTINE ABSORPTION;
MALE;
MOUSE;
NONHUMAN;
PHARMACOKINETICS;
PRIORITY JOURNAL;
RAT;
TRANSGENIC MOUSE;
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EID: 0033730609
PISSN: 09280987
EISSN: None
Source Type: Journal
DOI: 10.1016/S0928-0987(00)00144-5 Document Type: Article |
Times cited : (38)
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References (27)
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