Evidence for common genetic elements in allergic disease

Journal of Allergy and Clinical Immunology

Volumn 106, Issue 5 SUPPL., 2000, Pages

  Barnes, Kathleen C ^a  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Allergic rhinitis; Asthma; Phenotype

Indexed keywords

ALLERGIC DISEASE; ALLERGIC RHINITIS; ASTHMA; ATOPIC DERMATITIS; GENETIC SUSCEPTIBILITY; HUMAN; MAST CELL; PRIORITY JOURNAL; REVIEW;

EID: 0033695434     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1067/mai.2000.110150     Document Type: Article

References (79)

1. Demonstration of a common major gene with pleiotropic effects on immunoglobulin E levels and allergy
2. A genetic study of immunoglobulin E
3. Association of asthma with serum IgE levels and skin-test reactivity to allergens
4. Genetic and environmental risk factors for asthma: A cotwin-control study
5. Molecular studies of human response to allergens
6. Immunochemical and genetic studies of Amb.t. V (Ra5G), an Ra5 homologue from giant ragweed pollen
7. Specific IgE antibody responses to ragweed allergens Ra5S and Ra5G associated with distinct HLA-DR beta genes
8. Association of HLA-DR3 with human immune response to Lol p I and Lol p II allergens in allergic subjects
9. The specificity and regulation of T-cell responsiveness to allergens
10. HLA-DR2
11. Genetics of atopy and IgE
12. Epitope analysis of HLA-DR-restricted helper T-cell responses to Der p II, a major allergen molecule of Dermatophagoides pteronyssinus
13. Inflammatory mediators in late antigen-induced rhinitis
14. The influx of inflammatory cells into nasal washings during the late response to antigen challenge: Effect of systemic steroid pretreatment
15. Eosinophilic inflammation in asthma
16. Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects: The mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal inflammation
17. Bronchial epithelial cytokine production in asthmatics and nonasthmatics
18. Mucosal inflammation and asthma
19. T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma
20. One airway, one disease
21. Epidemiology and natural history of asthma, allergic rhinitis, and atopic dermatitis (eczema)
22. Airway hyperresponsiveness in allergic rhinitis: A risk factor for asthma
23. Rhinitis is ubiquitous in allergic asthmatics
24. Atopic dermatitis in early infancy predicts allergic airway disease at 5 years
25. A survey of childhood asthma in Aberdeen
26. Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases
27. Genetic dissection of complex traits
28. Symptoms and objective measures to define the asthma phenotype
29. Characterization of the MODY3 phenotype: Early-onset diabetes caused by an insulin secretion defect
30. Linkage of a gene causing high bone mass to human chromosome 11 (11q12-13)
31. Association between genetic variants of mast-cell chymase and eczema
32. Structure, chromosomal assignment, and deduced amino acid sequence of a human gene for mast cell chymase
33. The human mast cell chymase gene (CMA1): Mapping to the cathepsin G/granzyme gene cluster and lineage-restricted expression
34. Atopy and asthma genes-Where do we stand?
35. Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy
36. Association between a sequence variant in the IL-4 gene promoter and FEV(1) in asthma
37. Association of asthma and the interleukin-4 promoter gene in Japanese
38. Investigation of an interleukin-4 promoter polymorphism for associations with asthma and atopy
39. Indication of linkage of serum IgE levels to the interleukin-4 gene and exclusion of the contribution of the (-590 C to T) interleukin-4 promoter polymorphism to IgE variation
40. A polymorphism in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E
41. Interleukin-10 and transforming growth factor-beta promoter polymorphisms in allergies and asthma
42. A new variant of the beta subunit of the high-affinity receptor for immunoglobulin E (Fc epsilon RI-beta E237G): Associations with mensures of atopy and bronchial hyper-responsiveness
43. Atopic dermatitis is associated with a functional mutation in the promoter of the C-C chemokine RANTES
44. A genome-wide search for linkage to asthma: German Asthma Genetics Group
45. A genome-wide search for quantitative trait loci underlying asthma
46. Linkage of chromosome 5q and 11q gene markers to asthma-associated quantitative traits in Australian children
47. Dense mapping of chromosome 12q13.12-q23.3 and linkage to asthma and atopy
48. Linkage of asthma and total serum IgE concentration to markers on chromosome 12q: Evidence from Afro-Caribbean and Caucasian populations
49. Evidence for linkage of chromosome 12q15-q24.1 markers to high total serum IgE concentrations in children of the German Multicenter Allergy Study
50. Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11q
51. Confirmation of genetic linkage between atopic IgE responses and chromosome 11q13
52. Association between atopy and variants of the beta subunit of the high-affinity immunoglobulin E receptor
53. Linkage between severe atopy and chromosome 11q13 in Japanese families
54. Association between high serum total IgE levels and D11S97 on chromosome 11q13 in Japanese subjects
55. Allelic association of gene markers on chromosomes 5q and 11q with atopy and bronchial hyperresponsiveness
56. Linkage of high-affinity IgE receptor gene with bronchial hyperreactivity, even in absence of atopy
57. A genome-wide search for asthma susceptibility loci in ethnically diverse populations: The Collaborative Study on the Genetics of Asthma (CSGA)
58. Genome-wide search for asthma susceptibility loci in a founder population: The Collaborative Study on the Genetics of Asthma
59. Gene-environment interaction: Definitions and study designs
60. Genetic susceptibility to asthma: Bronchial hyperresponsiveness coinherited with a major gene for atopy
61. Evidence for linkage between asthma/atopy in childhood and chromosome 5q31-q33 in a Japanese population
62. Linkage and association of an interleukin 4 gene polymorphism with atopic dermatitis in Japanese families
63. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations
64. Evidence for a locus regulating total serum IgE levels mapping to chromosome 5
65. Genetic regulation of Dermatophagoides pteronyssinus-specific IgE responsiveness: A genome-wide multipoint linkage analysis in families recruited through 2 asthmatic sibs: Collaborative Study on the Genetics of Asthma (CSGA)
66. HLA haplotype segregation in families with allergic asthma
67. Evidence for linkage between the development of asthma in childhood and the T-cell receptor beta chain gene in Japanese
68. Linkage between atopy and the IgE high-affinity receptor gene at 11q13 in atopic dermatitis families
69. Linkage of asthma to markers on chromosome 12 in a sample of 240 families using quantitative phenotype scores
70. Linkage and association of atopic asthma to markers on chromosome 13 in the Japanese population
71. A physical map of the atopy locus on human chromosome 13q14
72. Genetic linkage of T-cell receptor alpha/delta complex to specific IgE responses
73. Suggestive evidence for genetic linkage between IgE phenotypes and chromosome 14q markers
74. Alternative G1m, G2m and G3m allotypes of IGHG genes correlate with atopic and nonatopic pathways of immune regulation in children with bronchial asthma
75. Linkage and allelic association of atopy and markers flanking the IL4-receptor gene
76. Asthma and bronchial hyperresponsiveness linked to the XY long arm pseudoautosomal region
77. Parametric and nonpammetric linkage analysis: A unified multipoint approach
78. A second-generation YAC contig map of human chromosome 12